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在“Elsevier电子期刊”中，命中：219条，耗时：0.043979 秒

在所有数据库中总计命中：319条

1.Vitamin D3 intake as regulator of insulin degrading enzyme and insulin receptor phosphorylation in diabetic rats

作者：Mohamed Mahmoud Elseweidy ; ^{mmelseweidy@yahoo.com} ; Rawia Sarhan Amin ; Hebatallah Husseini Atteia ; Maha Abdo Ali

关键词：Insulin degrading enzyme ; Insulin receptors phosphorylation ; Insulin resistance ; Glucagon ; Hyperlipidemia

刊名：Biomedicine & Pharmacotherapy

出版年：2017

2.High fat diet induces brain insulin resistance and cognitive impairment in mice

作者：Vishal Kothari^a ; Yuwen Luo^a ; Talia Tornabene^a ; Ann Marie O'Neill^b ; Michael W Greene^a ; Thangiah Geetha^c ; Jeganathan Ramesh Babu^a ; ^{jeganrb@auburn.edu}

关键词：AD ; Alzheimer disease ; APP ; amyloid precursor protein ; CREB ; CAMP-response element binding ; GFAP ; Glial Fibrillary Acidic Protein ; GTT ; glucose tolerance test ; HFD ; high fat diet ; HFS ; high fat diet with sugar ; HOMA ; homeostatic model assessment ; IDE ; insulin degrading enzyme ; IR ; insulin resistance ; ITT ; insulin tolerance test ; PSD ; postsynaptic density ; RQ ; respiratory exchange quotient ; SEM ; standard error of the mean ; T2DM ; type 2 diabetes

刊名：Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease

出版年：2017

3.Worsening of memory deficit induced by energy-dense diet in a rat model of early-Alzheimer's disease is associated to neurotoxic Aβ species and independent of neuroinflammation

作者：Pamela V. Martino Adami^a ; Pablo Galeano^a ; ^b ; Marina L. Wallinger^c ; Celia Quijano^d ; Alejandro Rabossi^e ; Eleonora S. Pagano^c ; Natividad Olivar^f ; Carlos Reyes Toso^c ; Daniel Cardinali^c ; Luis I. Brusco^f ; Sonia Do Carmo^g ; Rafael Radi^d ; Goar Gevorkian^h ; Eduardo M. Castañ ; o^a ; A. Claudio Cuello^g ; Laura Morelli^a ; ^{lmorelli@leloir.org.ar}

关键词：3-TyrNO2 ; 3-nitrotyrosine ; AβN3(pE) ; pyroglutamate-Aβ ; iAβ ; intraneuronal Aβ ; BBB ; blood-brain barrier ; BHI ; Bioenergetic Health Index ; CRTC ; CREB-regulated transcription coactivator ; IDE ; insulin degrading enzyme ; IR ; insulin resistance ; MetS ; metabolic syndrome ; OCR ; oxygen consumption rate ; PGC-1α ; PPARɣ coactivator 1α ; SD ; standard diet ; Sirt1 ; Sirtuin 1 ; SO ; stratum oriens ; SOD ; superoxide dismutase ; SP ; stratum pyramidale ; SRC ; spare respiratory capacity ; T2DM ; type 2 diabetes mellitus ; WA

刊名：Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease

出版年：2017

4.Insights into Substrate Unfolding and Allosteric Regulation of Insulin Degrading Enzyme

作者：Felicia H. Jiang¹ ; Wei-Jen Tang² ; Esmael J. Haddadian³

刊名：Biophysical Journal

出版年：2017

5.Targeting Insulin-Degrading Enzyme to Treat Type 2 Diabetes Mellitus

作者：Wei-Jen Tang¹ ; ^{wtang@uchicago.edu" class="auth_mail" title="E-mail the corresponding author}

关键词：insulin degrading enzyme ; type 2 diabetes mellitus ; Alzheimer's disease ; small molecule inhibitors

刊名：Trends in Endocrinology & Metabolism

出版年：2016

6.Characterization of insulin-degrading enzyme-mediated cleavage of Aβ in distinct aggregation states

作者：Ellen Hubin^a ; ^b ; ^c ; Federica Cioffi^a ; Jef Rozenski^d ; Nico A.J. van Nuland^b ; ^c ; ^{nvnuland@vub.ac.be" class="auth_mail" title="E-mail the corresponding author} ; Kerensa Broersen^a ; ^{k.broersen@utwente.nl" class="auth_mail" title="E-mail the corresponding author}

关键词：Amyloid-beta ; Insulin-degrading enzyme ; Neprilysin ; Alzheimer's disease ; Aggregation ; Aβ cleavage

刊名：Biochimica et Biophysica Acta (BBA) - General Subjects

出版年：2016

7.Diversity of insulin-like peptide signaling system proteins in Calanus finmarchicus (Crustacea; Copepoda) - Possible contributors to seasonal pre-adult diapause

作者：Andrew E. Christie ; ^{crabman@pbrc.hawaii.edu" class="auth_mail" title="E-mail the corresponding author} ; Vittoria Roncalli ; Petra H. Lenz

关键词：Transcriptomics ; Bioinformatics ; Insulin-like peptide (ILP) ; Insulin-like peptide receptor (ILPR) ; Insulin-degrading enzyme (IDE) ; Insulin receptor substrate (IRS) ; Forkhead box protein O (FOXO)

刊名：General and Comparative Endocrinology

出版年：2016

8.Hyperinsulinemia caused by dexamethasone treatment is associated with reduced insulin clearance and lower hepatic activity of insulin-degrading enzyme

作者：André ; Otá ; vio Peres Protzek^a ; Luiz Fernando Rezende^a ; José ; Maria Costa-Jú ; nior^a ; Sandra Mara Ferreira^a ; Ana Paula Gameiro Cappelli^a ; Flá ; via Maria Moura de Paula^a ; Jane Cristina de Souza^a ; Mirian Ayumi Kurauti^a ; Everardo Magalhã ; es Carneiro^a ; Alex Rafacho^b ; ^c ; ¹ ; ^{alex.rafacho@ufsc.br" class="auth_mail" title="E-mail the corresponding author} ; Antonio Carlos Boschero^a ; ¹ ; ^{boschero@unicamp.br" class="auth_mail" title="E-mail the corresponding author}

关键词：AI ; adrenal incidentaloma ; AD ; Alzheimeŕs disease ; AUC ; area-under-curve ; CTL ; saline-treated group ; CNTF ; ciliary neurotrophic factor ; GC ; glucocorticoid-treated group ; ipGTT ; intraperitoneal glucose tolerance test ; ipITT ; intraperitoneal insulin tolerance test ; IR ; insulin resistance ; KITT ; constant rate of glucose decay ; RIA ; radioimmunoassay ; T2DM ; type 2 diabetes mellitus

刊名：Journal of Steroid Biochemistry and Molecular Biology

出版年：2016

9.Changes in astrocyte functional markers and β-amyloid metabolism-related proteins in the early stages of hypercholesterolemia

作者：Y.L. Chen^a ; L.M. Wang^a ; Y. Chen^a ; J.Y. Gao^a ; C. Marshall^b ; Z.Y. Cai^c ; G. Hu^a ; M. Xiao^a ; ^{mingx@njmu.edu.cn" class="auth_mail" title="E-mail the corresponding author}

关键词：AD ; Alzheimer&rsquo ; s disease ; ADAM10 ; a-disintegrin and metalloproteinase 10 ; APOE ; apolipoprotein E ; APP ; amyloid precursor protein ; AQP4 ; aquaporin-4 ; Aβ ; β-amyloid ; BACE1 ; β-site amyloid precursor protein-cleaving enzyme 1 ; BBB ; blood&ndash ; brain barrier ; GFAP ; glial fibrillary acidic protein ; GLT1 ; glutamate transporter 1 ; Iba-1 ; ionized calcium-binding adaptor molecule 1 ; IDE ; insulin-degrading enzyme ; IL-1β ; interleukin-1β ; IL-6 ; interleukin-6 ; LRP1 ; low-density lipoprotein receptor-relat

刊名：Neuroscience

出版年：2016

10.TSPO ligand PK11195 alleviates neuroinflammation and beta-amyloid generation induced by systemic LPS administration

作者：Li Ma^a ; ^b ; ¹ ; Hui Zhang^c ; ¹ ; Na Liu^d ; Pei-qi Wang^a ; Wen-zhi Guo^b ; Qiang Fu^a ; Lin-bo Jiao^b ; Ya-qun Ma^b ; Wei-Dong Mi^a ; ^{mi_wd301@126.com" class="auth_mail" title="E-mail the corresponding author}

关键词：Aβ ; β-amyloid protein ; AD ; Alzheimer&rsquo ; s disease ; APP ; amyloid precursor protein ; BACE ; β-site APP cleaving enzyme ; BDNF ; brain-derived neurophic factor ; COX ; cyclooxygenase ; IDE ; insulin-degrading enzyme ; LPS ; lipopolysaccharide ; MWM ; Morris water maze ; SEM ; standard error of the mean ; TSPO ; translocator protein 18 ; kDa

刊名：Brain Research Bulletin

出版年：2016

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