搜索页_+half+maximal+effective+concentration

设为首页

收藏本站

网站地图 | English | 公务邮箱

远程访问

NSTL服务站

外文资源

Wiley电子期刊(7)	NATURE电子期刊(1)	ACS电子期刊(23)
SpringerLink电子期刊(78)	Elsevier电子期刊(253)

在“Elsevier电子期刊”中，命中：253条，耗时：小于0.01 秒

在所有数据库中总计命中：362条

1.In vitro combinatory effects of the Alternaria mycotoxins alternariol and altertoxin II and potentially involved miRNAs

作者：Katharina Vejdovszky^a ; Matej Sack^b ; Katharina Jarolim^a ; Georg Aichinger^a ; Mark M. Somoza^b ; Doris Marko^a ; ^{doris.marko@univie.ac.at}

关键词：AOH ; alternariol ; ATX II ; altertoxin II miRNA microRNA ; ddPCR ; droplet digital polymerase chain reaction ; PBS ; phosphate buffered saline ; FBS ; fetal bovine serum ; DMSO ; dimethyl sulfoxide ; EC50 ; half maximal effective concentration ; SEM ; standard error of the mean ; SD ; standard error of the mean

刊名：Toxicology Letters

出版年：2017

2.Synthesis and bioactivities of novel 2-(thioether/sulfone)-5-pyrazolyl-1,3,4-oxadiazole derivatives

作者：Yu-Tao Zheng^a ; ¹ ; Teng-Teng Zhang^a ; ¹ ; Pei-Yi Wang^a ; Zhi-Bing Wu^a ; Lei Zhou^a ; Yi-Qiang Ye^a ; Xiang Zhou^a ; Ming He^a ; Song Yang^a ; ^b ; ^{jhzx.msm@gmail.com}

关键词：Pyrazole ; 13 ; 4-Oxadiazole ; Synthesis ; Antibacterial ; Antifungal

刊名：Chinese Chemical Letters

出版年：2017

3.Targeted osteosarcoma chemotherapy using RGD peptide-installed doxorubicin-loaded biodegradable polymeric micelle

作者：Zhenhua Fang^a ; ¹ ; Yanpeng Sun^b ; ¹ ; Hong Xiao^a ; Peng Li^a ; Ming Liu^a ; Fan Ding^a ; Wusheng Kan^a ; Runsheng Miao^a ; ^{strongspine@163.com}

关键词：Osteosarcoma ; Targeted chemotherapy ; Nanoparticulate drug delivery system ; RGD

刊名：Biomedicine & Pharmacotherapy

出版年：2017

4.Unravelling intrinsic efficacy and ligand bias at G protein coupled receptors: A practical guide to assessing functional data

作者：Lisa A. Stott^a ; David A. Hall^b ; Nicholas D. Holliday^a ; ^{nicholas.holliday@nottingham.ac.uk" class="auth_mail" title="E-mail the corresponding author}

关键词：CRC ; concentration response curve ; EC50 ; effective agonist concentration for 50% maximum response ; Emax ; maximum system response ; GPCR ; G protein coupled receptor ; D2R ; dopamine D2 receptor ; GTPγS ; guanosine 5&prime ; -O-[γ-thio]triphosphate ; KA ; agonist equilibrium dissociation constant ; KE ; concentration of agonist&ndash ; receptor complex which produces a half maximal effect ; MAPK ; mitogen activated protein kinase ; RAi ; relative intrinsic activity ratio ; Rmax ; maximum agonist response ; RT ; total

刊名：Biochemical Pharmacology

出版年：2016

5.Oestrogen reporter transgenic medaka for non-invasive evaluation of aromatase activity

作者：Petra Spirhanzlova^a ; ^c ; Mathilde Leleu^a ; Anthony Sé ; billot^a ; Gregory F. Lemkine^a ; ^{lemkine@watchfrog.fr" class="auth_mail" title="E-mail the corresponding author} ; Taisen Iguchi^b ; Barbara A. Demeneix^c ; Andrew J. Tindall^a

关键词：Tam ; Tamoxifen ; Fad ; Fadrozole ; Dex ; Dexamethasone ; T3 ; 3 ; 3&prime ; 5&prime ; -triiodo-l-thyronine ; EE2 ; 17α-ethinyl oestradiol ; E2 ; 17β-oestradiol ; EC50 ; Effective concentration 50 (half maximal effective concentration) ; T ; Testosterone ; SEM ; Standard error of the mean ; EDCs ; Endocrine disrupting chemicals ; ChgH ; Choriogenin H ; GFP ; Green fluorescent protein ; DMSO ; Dimethyl sulfoxide ; MS222 ; Ethyl 3-aminobenzoate methanesulfonate ; dph ; Day post hatch ; ER ; Oestrogen receptor ; SERM ; Selective oestro

刊名：Comparative Biochemistry and Physiology, Part C

出版年：2016

6.Pharmacokinetics of dietary kaempferol and its metabolite 4-hydroxyphenylacetic acid in rats

作者：Volha Zabela^a ; ^{volha.zabela@unibas.ch} ; Chethan Sampath^b ; ^{chethan@ufl.edu} ; Mouhssin Oufir^a ; ^{mouhssin.oufir@unibas.ch} ; Fahimeh Moradi-Afrapoli^a ; Veronika Butterweck^b ; ¹ ; ^{veronika.butterweck@fhnw.ch} ; Matthias Hamburger^a ; ^{matthias.hamburger@unibas.ch}

关键词：AA ; acetic acid ; AIC ; Akaike's information criterion ; AUC ; area under the curve ; AUMC ; area under the first moment curve ; BBB ; blood-brain barrier ; b.w. ; body weight ; C0 ; concentration at time 0 ; CA ; compartmental analysis ; Cals ; calibrators ; CL ; clearance ; Cmax ; maximal concentration ; CV ; coefficient of variation ; FA ; formic acid ; 4-HPAA ; 4-hydroxyphenylacetic acid ; i.p. ; intraperitoneally ; IS ; internal standard ; i.v. ; intravenously ; ke ; elimination rate constant ; LLOQ ; lower limit of quantific

刊名：Fitoterapia

出版年：2016

7.Influence of amine-modified poly(vinyl alcohol)s on vibrating-membrane nebulizer performance and lung toxicity

作者：Moritz Beck-Broichsitter^a ; ^b ; ^{moritz.beck-broichsitter@innere.med.uni-giessen.de" class="auth_mail" title="E-mail the corresponding author} ; Olga Samsonova^b ; Juliane Nguyen^c ; Thomas Schmehl^a ; Werner Seeger^a ; Thomas Kissel^b

关键词：BALF ; bronchoalveolar lavage fluid ; BSA ; bovine serum albumin ; dd ; median geometric droplet diameter (based on the volume distribution) ; DEAPA-PVA ; 3-diethylamino-1-propylamine-modified poly(vinyl alcohol) ; EC50 ; half maximal effective polymer concentration inducing a halfway drop of the determined dd from baseline to a minimal size ; LDH ; lactate dehydrogenase ; p ; probability value ; SD ; standard deviation

刊名：European Journal of Pharmaceutical Sciences

出版年：2016

8.Monitoring genotoxicity in freshwater microcrustaceans: A new application of the micronucleus assay

作者：S. Barka^a ; Z. Ouanes^a ; ^b ; ^{zouhourouanes@yahoo.fr" class="auth_mail" title="E-mail the corresponding author} ; A. Gharbi^a ; I. Gdara^a ; S. Mouelhi^c ; A. Hamza-Chaffai^a

关键词：ANOVA ; analysis of variance ; D. magna ; Daphnia magna ; EC50 ; half maximal effective concentration ; LC50 ; lethal concentration 50% ; MN ; micronucleus ; ROS ; reactive oxygen species

刊名：Mutation Research/Genetic Toxicology and Environmental Mutagenesis

出版年：2016

9.Fragment-wise design of inhibitors to 3C proteinase from enterovirus 71

作者：Caiming Wu^a ; ^b ; ¹ ; Lanjun Zhang^b ; ¹ ; Peng Li^c ; ¹ ; Qixu Cai^b ; ¹ ; Xuanjia Peng^c ; Ke Yin^c ; Xinsheng Chen^c ; Haixia Ren^b ; Shilin Zhong^b ; Yuwei Weng^d ; Yi Guan^e ; Shuhui Chen^c ; Jinzhun Wu^a ; ^{1923731201@qq.com" class="auth_mail" title="E-mail the corresponding author} ; Jian Li^c ; ^{jian_li@wuxiapptec.com" class="auth_mail" title="E-mail the corresponding author} ; Tianwei Lin^b ; ^{twlin@xmu.edu.cn" class="auth_mail" title="E-mail the corresponding author}

关键词：HFMD ; hand ; foot and mouth disease ; 3Cpro ; 3C proteinase ; EV71 ; enterovirus 71 ; HRV ; human rhinovirus ; NMR ; nuclear magnetic resonance ; RP-HPLC ; reverse phase-high pressure liquid chromatography ; TFA ; trifluoroacetic acid ; LC ; liquid chromatography ; MS ; mass spectrometry ; FRET ; fluorescence resonance energy transfer ; DMSO ; dimethyl sulfoxide ; IC50 ; half maximal inhibitory concentration ; EC50 ; half maximal effective concentration ; μM ; micromolar ; r.m.s.d ; root mean square deviation ; DCM ; dichloro

刊名：Biochimica et Biophysica Acta (BBA) - General Subjects

出版年：2016

10.Traditional Japanese medicines inhibit compound action potentials in the frog sciatic nerve

作者：Akitomo Matsushita¹ ; ² ; ³ ; ^{ak10wx48@gmail.com" class="auth_mail" title="E-mail the corresponding author} ; Tsugumi Fujita² ; ³ ; ^{fujitat@cc.saga-u.ac.jp" class="auth_mail" title="E-mail the corresponding author} ; Sena Ohtsubo¹ ; ^{t0m3nyag0@yahoo.co.jp" class="auth_mail" title="E-mail the corresponding author} ; Eiichi Kumamoto ; ² ; ⁴

关键词：CAP ; compound action potential ; IC50 ; half-maximal inhibitory concentration ; nH ; Hill coefficient ; TRP ; transient receptor potential ; TRPA1 ; TRP ankyrin-1 ; TRPV1 ; TRP vanilloid-1

刊名：Journal of Ethnopharmacology

出版年：2016

按检索点细分(253)

关键词(62)

文摘(178)

按出版年细分(253)

2027年及以后(14)

2017年(3)

2016年(35)

2015年(14)

2013年(26)

2012年(22)

2011年(12)

2010年(12)

2009年(5)

2008年(8)

2007年(1)

2006年(5)

2005年(5)

2004年(12)

2003年(4)

2002年(4)

2001年(6)

2000年(9)

2000年及以前(56)

地址：北京市海淀区学院路29号邮编：100083

电话：办公室：(+86 10)66554848；文献借阅、咨询服务、科技查新：66554700