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Elsevier电子期刊(40)

在“Elsevier电子期刊”中，命中：40条，耗时：0.0480076 秒

在所有数据库中总计命中：56条

1.Statistical investigation of simulated fed intestinal media composition on the equilibrium solubility of oral drugs

作者：Zhou Zhou ; Claire Dunn ; Ibrahim Khadra ; Clive G. Wilson ; Gavin W. Halbert ; ^{g.w.halbert@strath.ac.uk}

关键词：BCS ; Biopharmaceutics Classification System ; DoE ; Design of Experiment ; FASSIF ; Fasted Simulated Intestinal Fluid ; FESSIF ; Fed Simulated Intestinal Fluid ; IVIVC ; In vitro In vivo correlation

刊名：European Journal of Pharmaceutical Sciences

出版年：2017

2.Dissolution behavior of co-amorphous amino acid-indomethacin mixtures: The ability of amino acids to stabilize the supersaturated state of indomethacin

作者：Rami Ojarinta^a ; ^{rami.ojarinta@uef.fi} ; Aki T. Heikkinen^b ; ^a ; Elina Sievä ; nen^c ; Riikka Laitinen^a

关键词：AA ; amino acid ; ACN ; acetonitrile ; ARG ; arginine ; AUC ; area under the curve ; CA ; co-amorphous ; DMSO ; dimethyl sulfoxide ; DS ; degree of supersaturation ; DSC ; differential scanning calorimetry ; EGF ; excipient gain factor ; FaSSIF ; fasted state simulated intestinal fluid ; FeSSIF ; fed state simulated intestinal fluid ; FTIR ; Fourier transform infrared spectroscopy ; HPLC ; high performance liquid chromatography ; IND ; indomethacin ; PHE ; phenylalanine ; PM ; physical mixture ; SF ; supersaturation factor ; ssN

刊名：European Journal of Pharmaceutics and Biopharmaceutics

出版年：2017

3.Evaluation of different in vitro dissolution tests based on level A in vitro-in vivo correlations for fenofibrate self-emulsifying lipid-based formulations

作者：Aude Pestieau^a ; ^{Aude.Pestieau@ulg.ac.be} ; Sonia Lebrun^b ; Bernard Cahay^b ; Adeline Brouwers^b ; Bruno Streel^b ; Jean-Michel Cardot^c ; Brigitte Evrard^a

关键词：Af ; absorbed API fraction without EHC ; API ; Active Pharmaceutical Ingredient ; AUC ; Area Under the Curve ; BCS ; Biopharmaceutics Classification System ; Cmax ; Maximal Concentration ; CS ; Saturation Concentration ; DSC ; Differential Scanning Calorimetry ; EHC ; EnteroHepatic Circulation ; EMA ; European Medicines Agency ; FaSSGF ; Fasted State Simulated Gastric Fluid ; FaSSIF ; Fasted State Simulated Intestinal Fluid ; FDA ; Food and Drug Administration ; FeSSIF ; Fed State Simulated Intestinal Fluid ; GIT ; Gastro

刊名：European Journal of Pharmaceutics and Biopharmaceutics

出版年：2017

4.Miniaturized INtrinsic DISsolution Screening (MINDISS) assay for preformulation

作者：Jochem Alsenz^a ; ^{jochem.alsenz@roche.com" class="auth_mail" title="E-mail the corresponding author} ; Elisabeth Haenel^a ; Aline Anedda^b ; Pauline Du Castel^a ; Giorgio Cirelli^a

关键词：DIDR ; disk intrinsic dissolution rate ; FaSSIF ; fasted simulated small intestinal fluid ; FeSSIF ; fed simulated small intestinal fluid ; MINDISS ; Miniaturized INtrinsic DISsolution Screening ; PASS ; partially automated solubility screening ; PEEK ; polyetherether ketone ; PRXAH ; piroxicam anhydrate ; PRXMH ; piroxicam monohydrate ; SGF ; simulated gastric fluid ; UPLC ; Ultra Performance Liquid Chromatography

刊名：European Journal of Pharmaceutical Sciences

出版年：2016

5.Evaluation of mesoporous carbon aerogels as carriers of the non-steroidal anti-inflammatory drug ibuprofen

作者：Georgios K. Eleftheriadis^a ; Maria Filippousi^b ; Vassiliki Tsachouridou^c ; ^d ; Maria-Anna Darda^a ; Lamprini Sygellou^d ; Ioanna Kontopoulou^e ; Nikolaos Bouropoulos^e ; Theodore Steriotis^f ; Georgia Charalambopoulou^f ; Ioannis S. Vizirianakis^c ; Gustaaf Van Tendeloo^b ; Dimitrios G. Fatouros^a ; ^{dfatouro@pharm.auth.gr}

关键词：Carbon aerogels ; Poorly soluble drugs ; Simulated intestinal fluids ; Oral delivery

刊名：International Journal of Pharmaceutics

出版年：2016

6.Use of physiologically relevant biopharmaceutics tools within the pharmaceutical industry and in regulatory sciences: Where are we now and what are the gaps?

作者：Talia Flanagan^a ; ^{Talia.Flanagan@AstraZeneca.com" class="auth_mail" title="E-mail the corresponding author} ; Achiel Van Peer^b ; Anders Lindahl^c

关键词：API ; active pharmaceutical ingredient ; APGI ; Association de Pharmacie Galé ; nique Industrielle ; BCS ; biopharmaceutical classification system ; EFPIA ; European Federation of Pharmaceutical Industry Association ; EMA ; European Medicines Agency ; FaSSIF ; fasted state simulated intestinal fluid ; FeSSIF ; fed state simulated intestinal fluid ; F2 ; dissolution similarity factor ; IND ; investigational new drug application ; IVIVC ; In vitro&ndash ; in vivo correlation ; IVIVR ; In vitro&ndash ; in vivo relation

刊名：European Journal of Pharmaceutical Sciences

出版年：2016

7.Supersaturation of zafirlukast in fasted and fed state intestinal media with and without precipitation inhibitors

作者：Cecilie Maria Madsen^a ; Ben Boyd^b ; Thomas Rades^a ; ^{Thomas.Rades@sund.ku.dk" class="auth_mail" title="E-mail the corresponding author} ; Anette Mü ; llertz^a ; ^c

关键词：Preformulation ; Food effects ; Precipitation inhibitors ; Amorphous ; Biorelevant media ; Bioavailability

刊名：European Journal of Pharmaceutical Sciences

出版年：2016

8.Cocrystals to facilitate delivery of poorly soluble compounds beyond-rule-of-5

作者：Gislaine Kuminek^a ; Fengjuan Cao^a ; Alanny Bahia de Oliveira da Rocha^b ; Simone Gonç ; alves Cardoso^b ; Naí ; r Rodrí ; guez-Hornedo^a ;

关键词：RCM ; Reaction crystallization method ; PSD ; Phase solubility diagram ; FeSSIF ; Fed state simulated intestinal fluid ; [drug]eu ; Drug concentration at the eutectic point ; [coformer]eu ; Coformer concentration at the eutectic point ; Keu ; Eutectic constant ; Keu &equiv ; [coformer]eu/[drug]eu ; Scocrystal ; Cocrystal solubility ; Sdrug ; Drug solubility ; Scoformer ; Solubility of coformer ; ST ; Total solubility in media with solubilizing agents ; ST ; = ; Saq ; + ; Ss ; Saq ; Aqueous solubility at a g

刊名：Advanced Drug Delivery Reviews

出版年：2016

9.Physicochemical properties and in vitro intestinal permeability properties and intestinal cell toxicity of silica particles, performed in simulated gastrointestinal fluids

作者：Kumiko Sakai-Kato ; Masayuki Hidaka ; Keita Un ; Toru Kawanishi ; Haruhiro Okuda

关键词：DDS ; drug delivery system ; PDI ; polydispersity index ; TEM ; transmission electron microscopy ; FaSSGF ; fasted-state simulated gastric fluids ; FeSSGF ; fed-state simulated gastric fluids ; FaSSIF ; fasted-state simulated intestinal fluids ; FeSSIF ; fed-state simulated intestinal fluids ; DMEM ; Dulbecco's modified Eagle's medium ; PBS ; Phosphate buffer saline ; HBSS ; Hanks' balanced salt solution ; FBS ; fetal bovine serum ; TEER ; transepithelial electrical resistance

刊名：Biochimica et Biophysica Acta (BBA)/General Subjects

出版年：March, 2014

10.Anhydrate to hydrate solid-state transformations of carbamazepine and nitrofurantoin in biorelevant media studied in situ using time-resolved synchrotron X-ray diffraction

作者：Johan P. Boetker^a ; Jukka Rantanen^a ; Læ ; rke Arnfast^a ; Maria Doreth^a ; Dhara Raijada^a ; ¹ ; Korbinian Loebmann^a ; Cecilie Madsen^a ; Jamal Khan^b ; Thomas Rades^a ; Anette Mü ; llertz^a ; Adrian Hawley^d ; Diana Thomas^e ; ² ; Ben J. Boyd^b ; ^c ; ^{ben.boyd@monash.edu" class="auth_mail" title="E-mail the corresponding author}

关键词：Carbamazepine ; Nitrofurantoin ; Solution-mediated transformation ; Synchrotron ; PCA ; Micelles

刊名：European Journal of Pharmaceutics and Biopharmaceutics

出版年：2016

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