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Elsevier电子期刊(70)

在“Elsevier电子期刊”中，命中：70条，耗时：0.0529407 秒

在所有数据库中总计命中：92条

1.Statistical investigation of simulated fed intestinal media composition on the equilibrium solubility of oral drugs

作者：Zhou Zhou ; Claire Dunn ; Ibrahim Khadra ; Clive G. Wilson ; Gavin W. Halbert ; ^{g.w.halbert@strath.ac.uk}

关键词：BCS ; Biopharmaceutics Classification System ; DoE ; Design of Experiment ; FASSIF ; Fasted Simulated Intestinal Fluid ; FESSIF ; Fed Simulated Intestinal Fluid ; IVIVC ; In vitro In vivo correlation

刊名：European Journal of Pharmaceutical Sciences

出版年：2017

2.Dissolution behavior of co-amorphous amino acid-indomethacin mixtures: The ability of amino acids to stabilize the supersaturated state of indomethacin

作者：Rami Ojarinta^a ; ^{rami.ojarinta@uef.fi} ; Aki T. Heikkinen^b ; ^a ; Elina Sievä ; nen^c ; Riikka Laitinen^a

关键词：AA ; amino acid ; ACN ; acetonitrile ; ARG ; arginine ; AUC ; area under the curve ; CA ; co-amorphous ; DMSO ; dimethyl sulfoxide ; DS ; degree of supersaturation ; DSC ; differential scanning calorimetry ; EGF ; excipient gain factor ; FaSSIF ; fasted state simulated intestinal fluid ; FeSSIF ; fed state simulated intestinal fluid ; FTIR ; Fourier transform infrared spectroscopy ; HPLC ; high performance liquid chromatography ; IND ; indomethacin ; PHE ; phenylalanine ; PM ; physical mixture ; SF ; supersaturation factor ; ssN

刊名：European Journal of Pharmaceutics and Biopharmaceutics

出版年：2017

3.A novel microdialysis-dissolution/permeation system for testing oral dosage forms: A proof-of-concept study

作者：Sophia Yui Kau Fong ; Jessie Poulsen ; Martin Brandl ; Annette Bauer-Brandl ; ^{annette.bauer@sdu.dk}

关键词：D/P system ; dissolution/permeation system ; DSC ; differential scanning calorimetry ; FaSSIF ; fasted state simulated intestinal fluid ; HCS ; hydrocortisone ; IS ; internal standard ; Jss ; steady-state flux ; LLOD ; lower limit of detection ; LLOQ ; lower limit of quantification ; M-D/P system ; microdialysis-dissolution/permeation system ; MWCO ; molecular weight cut-off ; PBS ; phosphate buffer saline ; QC ; quality control ; RSD ; relative standard deviation ; UHPLC-UV ; Ultra-High-Performance Liquid Chromatography-

刊名：European Journal of Pharmaceutical Sciences

出版年：2017

4.Evaluation of different in vitro dissolution tests based on level A in vitro-in vivo correlations for fenofibrate self-emulsifying lipid-based formulations

作者：Aude Pestieau^a ; ^{Aude.Pestieau@ulg.ac.be} ; Sonia Lebrun^b ; Bernard Cahay^b ; Adeline Brouwers^b ; Bruno Streel^b ; Jean-Michel Cardot^c ; Brigitte Evrard^a

关键词：Af ; absorbed API fraction without EHC ; API ; Active Pharmaceutical Ingredient ; AUC ; Area Under the Curve ; BCS ; Biopharmaceutics Classification System ; Cmax ; Maximal Concentration ; CS ; Saturation Concentration ; DSC ; Differential Scanning Calorimetry ; EHC ; EnteroHepatic Circulation ; EMA ; European Medicines Agency ; FaSSGF ; Fasted State Simulated Gastric Fluid ; FaSSIF ; Fasted State Simulated Intestinal Fluid ; FDA ; Food and Drug Administration ; FeSSIF ; Fed State Simulated Intestinal Fluid ; GIT ; Gastro

刊名：European Journal of Pharmaceutics and Biopharmaceutics

出版年：2017

5.Miniaturized INtrinsic DISsolution Screening (MINDISS) assay for preformulation

作者：Jochem Alsenz^a ; ^{jochem.alsenz@roche.com" class="auth_mail" title="E-mail the corresponding author} ; Elisabeth Haenel^a ; Aline Anedda^b ; Pauline Du Castel^a ; Giorgio Cirelli^a

关键词：DIDR ; disk intrinsic dissolution rate ; FaSSIF ; fasted simulated small intestinal fluid ; FeSSIF ; fed simulated small intestinal fluid ; MINDISS ; Miniaturized INtrinsic DISsolution Screening ; PASS ; partially automated solubility screening ; PEEK ; polyetherether ketone ; PRXAH ; piroxicam anhydrate ; PRXMH ; piroxicam monohydrate ; SGF ; simulated gastric fluid ; UPLC ; Ultra Performance Liquid Chromatography

刊名：European Journal of Pharmaceutical Sciences

出版年：2016

6.Evaluation of mesoporous carbon aerogels as carriers of the non-steroidal anti-inflammatory drug ibuprofen

作者：Georgios K. Eleftheriadis^a ; Maria Filippousi^b ; Vassiliki Tsachouridou^c ; ^d ; Maria-Anna Darda^a ; Lamprini Sygellou^d ; Ioanna Kontopoulou^e ; Nikolaos Bouropoulos^e ; Theodore Steriotis^f ; Georgia Charalambopoulou^f ; Ioannis S. Vizirianakis^c ; Gustaaf Van Tendeloo^b ; Dimitrios G. Fatouros^a ; ^{dfatouro@pharm.auth.gr}

关键词：Carbon aerogels ; Poorly soluble drugs ; Simulated intestinal fluids ; Oral delivery

刊名：International Journal of Pharmaceutics

出版年：2016

7.Formulation and characterization of self-nanoemulsifying drug delivery systems containing monoacyl phosphatidylcholine

作者：Thuy Tran^a ; Xi Xi^a ; Thomas Rades^a ; Anette Mü ; llertz^a ; ^b ; ^{anette.mullertz@sund.ku.dk" class="auth_mail" title="E-mail the corresponding author}

关键词：Cryo-TEM ; cryogenic transmission electron microscopy ; DoE ; design of experiments ; FaSSGFTDC ; fasted-state simulated gastric fluid containing sodium taurodeoxycholate ; FaMIF ; fasted-state median intestinal fluid ; LC ; long-chain ; LPC ; Lipoid S LPC 80 ; MAPC ; monoacyl phosphatidylcholine ; MC ; medium-chain ; PC ; phosphatidylcholine ; SNEDDS ; self-nanoemulsifying drug delivery systems

刊名：International Journal of Pharmaceutics

出版年：2016

8.PLGA nanoparticles for peroral delivery: How important is pancreatic digestion and can we control it?

作者：Anika Mante¹ ; ² ; ^{anika.mante@medizin.uni-leipzig.de" class="auth_mail" title="E-mail the corresponding author} ; Martha Heider¹ ; ^{martha.heider@pharmazie.uni-halle.de" class="auth_mail" title="E-mail the corresponding author} ; Christin Zlomke ^{christin.zlomke@pharmazie.uni-halle.de" class="auth_mail" title="E-mail the corresponding author} ; Karsten Mä ; der ; ^{Maeder@pharmazie.uni-halle.de" class="auth_mail" title="E-mail the corresponding author}

关键词：FaSSIF ; fasted state simulated intestinal fluid ; FeSSIF ; simulated state intestinal fluid ; NPs ; nanoparticles ; PDI ; polydispersity index ; PEG-PLA ; pegylated poly(lactic acid) ; PLA ; poly(lactic acid) ; PLGA ; poly(lactideglycolic acid) ; PVA ; Poly(vinyl alcohol) ; Tris ; tris(hydroxymethyl)-aminomethan ; z-aver ; z-average

刊名：European Journal of Pharmaceutics and Biopharmaceutics

出版年：2016

9.Design, synthesis, and evaluation of novel porcupine inhibitors featuring a fused 3-ring system based on the ‘reversed’ amide scaffold

作者：Zhixiang Xu^a ; ^&dagger ; ; Xiangxiang Xu^a ; ^&dagger ; ; Ruadhan O&rsquo ; Laoi^b ; Haikuo Ma^a ; Jiyue Zheng^a ; ^{jyzheng@suda.edu.cn" class="auth_mail" title="E-mail the corresponding author} ; Shuaishuai Chen^c ; Lusong Luo^c ; ^{lusong.luo@beigene.com" class="auth_mail" title="E-mail the corresponding author} ; Zhilin Hu^d ; Sudan He^d ; Jiajun Li^a ; Hongjian Zhang^a ; Xiaohu Zhang^a ; ^{xiaohuzhang@suda.edu.cn" class="auth_mail" title="E-mail the corresponding author}

关键词：BPO ; benzoyl peroxide ; DCM ; dichloromethane ; DIPEA ; N ; N-diisopropylethylamine ; DMF ; N ; N-dimethylformamide ; DMSO ; dimethyl sulfoxide ; FaSSIF ; fasted state simulated intestinal fluid ; HATU ; 1-[bis(dimethylamino)methylene]-1H-12 ; 3-triazolo[4 ; 5-b]pyridinium 3-oxid hexafluorophosphate ; SEM ; standard error measurement ; SGF ; simulated gastric fluid ; STF ; super-top flash ; TFA ; trifluoroacetic acid

刊名：Bioorganic & Medicinal Chemistry

出版年：2016

10.Use of physiologically relevant biopharmaceutics tools within the pharmaceutical industry and in regulatory sciences: Where are we now and what are the gaps?

作者：Talia Flanagan^a ; ^{Talia.Flanagan@AstraZeneca.com" class="auth_mail" title="E-mail the corresponding author} ; Achiel Van Peer^b ; Anders Lindahl^c

关键词：API ; active pharmaceutical ingredient ; APGI ; Association de Pharmacie Galé ; nique Industrielle ; BCS ; biopharmaceutical classification system ; EFPIA ; European Federation of Pharmaceutical Industry Association ; EMA ; European Medicines Agency ; FaSSIF ; fasted state simulated intestinal fluid ; FeSSIF ; fed state simulated intestinal fluid ; F2 ; dissolution similarity factor ; IND ; investigational new drug application ; IVIVC ; In vitro&ndash ; in vivo correlation ; IVIVR ; In vitro&ndash ; in vivo relation

刊名：European Journal of Pharmaceutical Sciences

出版年：2016

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