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Elsevier电子期刊(253)

在“Elsevier电子期刊”中，命中：253条，耗时：小于0.01 秒

在所有数据库中总计命中：253条

1.Neuroprotective effects of N-adamantyl-4-methylthiazol-2-amine against amyloid β-induced oxidative stress in mouse hippocampus

作者：Jiae Kim^a ; Chang Hun Cho^a ; Hoh-Gyu Hahn^b ; Soo-Young Choi^c ; Sung-Woo Cho^a ; ^{swcho@amc.seoul.kr}

关键词：Aβ ; amyloidβ ; AD ; Alzheimer&rsquo ; s disease ; cPLA2 ; cytosolic phospholipase A2 ; DCF ; DA 2&prime ; 7&prime ; -dichlorofluorescin diacetate ; CAT ; catalase ; DMSO ; dimethyl-sulfoxide ; EDTA ; ethylenediaminetetraacetic acid ; GPx ; glutathione peroxidase ; GSH ; reduced glutathione ; HO-1 ; heme oxygenase 1 ; IL-1β ; Interleukin-1 beta ; iNOS ; including nitric oxide synthase ; MDA ; malondialdehyde ; MMP-2 ; matrix metalloproteinase-2 ; Nrf2 ; nuclear factor-erythroid 2-related factor 2 ; ROS ; reactive oxygen species ; S

刊名：Brain Research Bulletin

出版年：2017

2.Pathological α-synuclein exacerbates the progression of Parkinson’s disease through microglial activation

作者：Qiu-Shuang Zhang^a ; Yang Heng^a ; Yu-He Yuan^a ; ^{yuanyuhe@imm.ac.cn} ; Nai-Hong Chen^a ; ^b ; ^{chennh@imm.ac.cn}

关键词：AKT ; protein kinase B ; AP-1 ; activator protein-1 ; BV-2 ; immortalized murine microglia cell line ; CD11b ; cluster of differentiation 11b ; CD36 ; cluster of differentiation 36 ; CD44 ; cluster of differentiation 44 ; CD68 ; cluster of differentiation 68 ; CNS ; central nervous system ; COX-2 ; cyclooxygenase-2 ; cPLA2 ; cytosolic phospholipase A2 ; EP2 ; prostaglandin E2 receptor subtype 2 ; ERK ; extracellular regulated kinases ; FcγRs ; Fc gamma receptors ; IKK ; IκB kinase ; IL-1β ; interleukin-1-β ; IL-6 ; interleuki

刊名：Toxicology Letters

出版年：2017

3.Structure-activity relationship studies on 1-(2-oxopropyl)indole-5-carboxylic acids acting as inhibitors of cytosolic phospholipase A₂α: Effect of substituents at the indole 3-position on activity, solubility, and metabolic stability

作者：Martina Arnsmann ; Walburga Hanekamp ; Alwine Schulze Elfringhoff ; Matthias Lehr ; ^{lehrm@uni-muenster.de}

关键词：Cytosolic phospholipase A2α ; Inhibitors ; Indole derivatives ; Metabolic stability ; Ketone reduction ; Glucuronidation ; Aqueous solubility

刊名：European Journal of Medicinal Chemistry

出版年：2017

4.2-Oxoamides based on dipeptides as selective calcium-independent phospholipase A₂ inhibitors

作者：Anneta Smyrniotou^a ; Maroula G. Kokotou^b ; ^c ; Varnavas D. Mouchlis^c ; Efrosini Barbayianni^b ; George Kokotos^b ; Edward A. Dennis^c ; ^{edennis@ucsd.edu} ; Violetta Constantinou-Kokotou^a ; ^vikon@aua.gr

关键词：Dipeptides ; Inhibitors ; Oxoamides ; Phospholipase A2 ; Pseudodipeptides

刊名：Bioorganic & Medicinal Chemistry

出版年：2017

5.UCN enhances TGF-beta-mediated mitoinhibition of VSMCs via counteracting TGF-beta-induced cPLA2 expression and activation

作者：Chao Zhu ; Changchun Cao ; Xiaofei Wang ; Jie Yuan ; Lai Jin ; Shengnan Li ; ^{snli@njmu.edu.cn" class="auth_mail" title="E-mail the corresponding author}

关键词：Ast ; astressin ; cPLA2 ; cytosolic phospholipase A2 ; CRF ; corticotrophin-releasing factor ; CRFR ; corticotrophin-releasing factor receptor ; PYR ; pyrrophenone ; UCN ; urocortin ; mitoinhibition ; mitosis inhibition

刊名：International Journal of Biochemistry and Cell Biology

出版年：2016

6.Ketogenic diet change cPLA2/clusterin and autophagy related gene expression and correlate with cognitive deficits and hippocampal MFs sprouting following neonatal seizures

作者：Hong Ni^a ; ^{nyr2000@yeah.net" class="auth_mail" title="E-mail the corresponding author} ; ^{nhdoctor@163.com" class="auth_mail" title="E-mail the corresponding author} ; Dong-jing Zhao^a ; Tian Tian^a ; ^b

关键词：Ketogenic diet ; Cpla2 ; Clusterin ; Autophagy ; Neonatal seizure

刊名：Epilepsy Research

出版年：2016

7.Caged ceramide 1-phosphate (C1P) analogs: Novel tools for studying C1P biology

作者：Antonio Gomez-Muñ ; oz ; ^{antonio.gomez@ehu.es" class="auth_mail" title="E-mail the corresponding author} ; Patricia Gangoiti ; Io-Guané ; Rivera ; Natalia Presa ; Ana Gomez-Larrauri ; Marta Ordoñ ; ez

关键词：Akt (PKB) ; protein kinase ; B BHNB ; 4-bromo-5-hydroxy-2-nitrobenzhydryl ; BMDM ; bone marrow-derived macrophages ; CerK ; ceramide kinase ; C1P ; ceramide 1-phosphate ; cPLA2 ; calcium-dependent cytosolic phospholipase 2 ; DECM ; 7-(N ; N-diethylamino)coumarin ; ERK ; extracellularly regulated kinases ; GLUT ; glucose transporter ; iNOS ; inducible nitric oxide synthase ; PKC ; protein kinase C ; PI3K ; phosphatidylinositol 3-kinase ; PTX ; pertussis toxin ; ROS ; reacfive oxygen species ; SMase ; sphingomyelinase ; SPT ; ser

刊名：Chemistry and Physics of Lipids

出版年：2016

8.Control of inflammatory responses by ceramide, sphingosine 1-phosphate and ceramide 1-phosphate

作者：Antonio Gomez-Muñ ; oz^a ; ^{antonio.gomez@ehu.es" class="auth_mail" title="E-mail the corresponding author} ; Natalia Presa^a ; ^{npretor@gmail.com" class="auth_mail" title="E-mail the corresponding author} ; Ana Gomez-Larrauri^b ; ^{ana.gomezlarrauri@osakidetza.net" class="auth_mail" title="E-mail the corresponding author} ; Io-Guané ; Rivera^a ; ^{io_rivera@hotmail.com" class="auth_mail" title="E-mail the corresponding author} ; Miguel Trueba^a ; ^{miguel.trueba@ehu.es" class="auth_mail" title="E-mail the corresponding author} ; Marta Ordoñ ; ez^a ; ^{marta.ordonez87@gmail.com" class="auth_mail" title="E-mail the corresponding author}

关键词：Akt (PKB) ; protein kinase ; CerK ; ceramide kinase ; C1P ; ceramide 1-phosphate ; cPLA2 ; calcium-dependent cytosolic phospholipase 2 ; ERK ; extracellularly regulated kinases ; iNOS ; inducible nitric oxide synthase ; PKC ; protein kinase C ; PI3K ; phosphatidylinositol 3-kinase ; ROS ; reactive oxygen species ; SMase ; sphingomyelinase ; SPT ; serine palmitoyl transferase

刊名：Progress in Lipid Research

出版年：2016

9.Off-target effect of the cPLA₂α inhibitor pyrrophenone: Inhibition of calcium release from the endoplasmic reticulum

作者：Bogeon Yun^a ; HeeJung Lee^a ; Heather Ewing^b ; Michael H. Gelb^b ; Christina C. Leslie^a ; ^{lesliec@njhealth.org" class="auth_mail" title="E-mail the corresponding author}

关键词：cPLA2α ; Calcium ; Pyrrophenone ; Endoplasmic reticulum ; Mitochondria

刊名：Biochemical and Biophysical Research Communications

出版年：2016

10.BRP-187: A potent inhibitor of leukotriene biosynthesis that acts through impeding the dynamic 5-lipoxygenase/5-lipoxygenase-activating protein (FLAP) complex assembly

关键词：5-LO ; 5-lipoxygenase ; AA ; arachidonic acid ; COX ; cyclooxygenase ; cPLA2 ; cytosolic phospholipase A2 ; FLAP ; 5-lipoxygenase-activating protein ; fMLP ; N-formyl-methionyl-leucyl-phenylalanine ; H(P)ETE ; hydro(pero)oxyeicosatetraenoic acid ; HHT ; hydroxyheptadecatrienoic acid ; IL ; interleukin ; LPS ; lipopolysaccharide ; LT ; leukotriene ; mPGES-1 ; microsomal prostaglandin E2 synthase 1 ; MPO ; myeloperoxidase ; PG ; phosphate-buffered saline plus 1 ; mg/ml glucose ; PGC ; phosphate-buffered saline plus 1

刊名：Biochemical Pharmacology

出版年：2016

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