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Elsevier电子期刊(26)

在“Elsevier电子期刊”中，命中：26条，耗时：0.0129952 秒

在所有数据库中总计命中：30条

1.Lymphocytes contribute to biliary injury and fibrosis in experimental xenobiotic-induced cholestasis

作者：Nikita Joshi^a ; ^b ; ^c ; Anna K. Kopec^b ; ^c ; Holly Cline-Fedewa^b ; James P. Luyendyk^a ; ^b ; ^c ; ^{luyendyk@cvm.msu.edu}

关键词：ANIT ; alpha-naphthylisothiocyanate ; CK-19 ; cytokeratin-19 ; ALT ; alanine aminotransferase ; ALP ; alkaline phosphatase ; TGFβ ; transforming growth factor beta ; COL1A1 ; type I collagen ; ITGβ6 ; integrin beta 6 ; αVβ6 ; alphaVbeta6 integrin ; PBC ; primary biliary cirrhosis ; PSC ; primary sclerosing cholangitis ; BDEC ; bile duct epithelial cell

刊名：Toxicology

出版年：2017

2.Effects of andrographolide on intrahepatic cholestasis induced by alpha-naphthylisothiocyanate in rats

作者：Tanaporn Khamphaya^a ; Piyachat Chansela^b ; Pawinee Piyachaturawat^c ; Apichart Suksamrarn^d ; Michael H. Nathanson^e ; Jittima Weerachayaphorn^c ; ^e ; ^{jittima.wee@mahidol.ac.th" class="auth_mail" title="E-mail the corresponding author} ; ^{jittima.weerachayaphorn@yale.edu" class="auth_mail" title="E-mail the corresponding author}

关键词：Alpha-naphthylisothiocyanate (PubChem CID ; 11080) ; Andrographolide (PubChem CID ; 5318517) ; Carboxymethylcellulose Sodium (PubChem CID ; 23706213)

刊名：European Journal of Pharmacology

出版年：2016

3.Alpha-naphthylisothiocyanate impairs bile acid homeostasis through AMPK-FXR pathways in rat primary hepatocytes

作者：Xiaojiaoyang Li^a ; Runping Liu^c ; Linxi Yu^a ; Zihang Yuan^a ; Rong Sun^d ; Hang Yang^a ; Luyong Zhang^a ; ^b ; Zhenzhou Jiang^a ; ^b ; ^{beaglejiang@cpu.edu.cn" class="auth_mail" title="E-mail the corresponding author}

关键词：ANIT ; alpha-naphthylisothiocyanate ; A1AR ; A1 adenosine receptor ; FXR ; farnesoid X receptor ; SHP ; small heterodimer partner ; Bsep ; bile salt export pump ; Mrp2 ; multidrug resistance-associated protein 2 ; Ntcp ; Na+-dependent taurocholate cotransporter ; Oatp2 ; organic anion transporters 2 ; Mrp3 ; multidrug resistance-associated protein 3 ; AMPK ; AMP-activated protein kinase ; LKB1 ; liver kinase B1 ; ERK1/2 ; extracellular regulated protein kinases 1/2 ; PKA ; cyclic AMP dependent protein kinase

刊名：Toxicology

出版年：2016

4.Target profiling analyses of bile acids in the evaluation of hepatoprotective effect of gentiopicroside on ANIT-induced cholestatic liver injury in mice

作者：Xiaowen Tang^a ; ^{shs912vv@126.com} ; Qiaoling Yang^a ; ^{cherish0814@126.com} ; Fan Yang^a ; ^{sailseem1111@hotmail.com} ; Junting Gong^a ; ^{576621831@qq.com} ; Han Han^a ; ^{837270636@qq.com} ; Li Yang^a ; ^b ; ^{yangli7951@hotmail.com} ; Zhengtao Wang^a

关键词：Cholestasis ; Alpha-naphthylisothiocyanate (ANIT) ; Gentiopicroside (GPS) ; Bile acids (BAs) ; Traditional Chinese Medicine

刊名：Journal of Ethnopharmacology

出版年：2016

5.Inhibition of PAR-4 and P2Y₁₂ receptor-mediated platelet activation produces distinct hepatic pathologies in experimental xenobiotic-induced cholestatic liver disease

作者：Nikita Joshi^a ; ^c ; Anna K. Kopec^b ; ^c ; Jessica L. Ray^b ; James P. Luyendyk^a ; ^b ; ^c ; ^{luyendyk@cvm.msu.edu" class="auth_mail" title="E-mail the corresponding author}

关键词：ANIT ; alpha-naphthylisothiocyanate ; ADP ; adenosine diphosphate ; PAR ; protease activated receptor ; H&E ; hematoxylin and eosin ; CK-19 ; cytokeratin-19 ; ALT ; alanine aminotransferase ; TGFβ ; transforming growth factor beta ; COL1A1 ; type I collagen ; ITGβ6 ; integrin beta 6 ; TIMP1 ; tissue inhibitor of matrix metalloproteinase 1 ; αIIbβ3 ; alphaIIbbetaIIIintegrin ; αVβ6 ; alphaVbeta6 integrin

刊名：Toxicology

出版年：2016

6.Endogenous glucocorticoids exacerbate cholestasis-associated liver injury and hypercholesterolemia in mice

作者：Rick van der Geest^a ; ^{r.van.der.geest@lacdr.leidenuniv.nl" class="auth_mail" title="E-mail the corresponding author} ; Amber B. Ouweneel^a ; ^{a.b.ouweneel@lacdr.leidenuniv.nl" class="auth_mail" title="E-mail the corresponding author} ; Ronald J. van der Sluis^a ; ^{r.vandersluis@lacdr.leidenuniv.nl" class="auth_mail" title="E-mail the corresponding author} ; Albert K. Groen^b ; ^{a.k.groen@umcg.nl" class="auth_mail" title="E-mail the corresponding author} ; Miranda Van Eck^a ; ^{m.eck@lacdr.leidenuniv.nl" class="auth_mail" title="E-mail the corresponding author} ; Menno Hoekstra^a ; ^{hoekstra@lacdr.leidenuniv.nl" class="auth_mail" title="E-mail the corresponding author}

关键词：ABCB4 ; ATP-binding cassette transporter B4 ; ADX ; adrenalectomy ; ALT/GPT ; alanine transaminase/glutamic pyruvic transaminase ; ANIT ; alpha-naphthylisothiocyanate ; APOA4 ; apolipoprotein A4 ; BSEP/ABCB11 ; bile salt efflux pump ; CYP7A1 ; cholesterol 7alpha-hydroxylase ; FXR/BAR ; farnesoid X receptor/bile acid receptor ; HDL ; high-density lipoprotein ; HMGCR ; HMG-CoA reductase ; LDL ; low-density lipoprotein ; LDLR ; low-density lipoprotein receptor ; NTCP1/SLC10A1 ; sodium/bile acid cotransporter member 1 ; PEPC

刊名：Toxicology and Applied Pharmacology

出版年：2016

7.A synthetic biology-based device prevents liver injury in mice

作者：Peng Bai¹ ; Haifeng Ye¹ ; ² ; Mingqi Xie¹ ; Pratik Saxena¹ ; Henryk Zulewski¹ ; ³ ; ⁴ ; Ghislaine Charpin-El Hamri⁵ ; Valentin Djonov⁶ ; Martin Fussenegger¹ ; ⁷ ; ^{fussenegger@bsse.ethz.ch" class="auth_mail" title="E-mail the corresponding author}

关键词：HGF ; hepatocyte growth factor ; PKA ; cAMP-dependent phosphokinase A ; CRE ; cAMP-response element ; PCRE ; CRE-containing synthetic mammalian promoter ; SEAP ; human placental secreted alkaline phosphatase ; CREm ; modified cAMP-response element ; PCREm ; modified PCRE variant ; TUDCA ; tauroursodeoxycholic acid ; shGLP1 ; short human glucacon-like peptide 1 ; SBA ; serum bile acid ; CCl4 ; Carbon tetrachloride ; ANIT ; alpha-naphthylisothiocyanate

刊名：Journal of Hepatology

出版年：2016

8.Dioscin protects against ANIT-induced cholestasis via regulating Oatps, Mrp2 and Bsep expression in rats

关键词：ALT ; alanine amiotransferase ; ANIT ; alpha-naphthylisothiocyanate ; AST ; aspartate transaminase ; BIL ; bilirubin ; Bsep ; bile salt export pump ; CMC-Na ; carboxymethylcellulose sodium ; E3S ; estrone-3-sulfate ; FXR ; Farnesoid X receptor ; IS ; hydrochlorothiazide ; LC-MS/MS ; liquid chromatography-tandem mass spectrometry ; Mrp ; multidrug resistance-associated protein ; Ntcp ; Na+-taurocholate cotransporting polypeptide ; Oatp ; organic anion transporting polypeptide ; qRT-PCR ; Quantitive Real Time-polymerase cha

刊名：Toxicology and Applied Pharmacology

出版年：2016

9.Alpha-naphthylisothiocyanate modulates hepatobiliary transporters in sandwich-cultured rat hepatocytes

作者：Cen Guo ; Lei He ; Dan Yao ; Jiye A ; Bei Cao ; Jin Ren ; Guangji Wang ; Guoyu Pan

关键词：SCRH ; sandwich-cultured rat hepatocytes ; ANIT ; alpha-naphthylisothiocyanate ; Mrp ; multidrug resistance-associated protein ; Bsep ; bile salt export pump ; Ntcp ; sodium/taurocholate cotransporting polypeptide ; Oatp ; organic anion transporting polypeptide ; BEI ; biliary excretion index ; Clbiliary ; biliary clearance ; IPRLs ; isolated perfused rat livers ; BECs ; biliary epithelial cells ; Cyp7a1 ; cholesterol 7伪-hydroxylase ; Cyp27a1 ; sterol 27-hydroxylase ; Cyp8b1 ; sterol 12伪-hydroxylase ; CDF ; 5 (and 6)-ca

刊名：Toxicology Letters

出版年：3 January, 2014

10.Characterization of animal models for primary sclerosing cholangitis (PSC)

作者：Peter Fickert¹ ; ² ; ^&dagger ; ; ^{peter.fickert@medunigraz.at" class="auth_mail} ; Marion J. Pollheimer¹ ; ² ; ^&dagger ; ; Ulrich Beuers³ ; Carolin Lackner² ; Gideon Hirschfield⁴ ; Chantal Housset⁵ ; Verena Keitel⁶ ; Christoph Schramm⁷ ; Hanns-Ulrich Marschall⁸ ; Tom H. Karlsen⁹ ; ¹⁰ ; ¹¹ ; ¹² ; Espen Melum⁹ ; ¹⁰ ; ¹¹ ; Arthur Kaser¹³ ; Bertus Eksteen¹⁴ ; Mario Strazzabosco¹⁵ ; ¹⁶ ; Michael Manns¹⁷ ; Michael Trauner¹⁸ ; ^{michael.trauner@meduniwien.ac.at" class="auth_mail} ; for the International PSC Study Group (IPSCSG)

关键词：ANA ; anti-nuclear antibody ; ANCA ; anti-neutrophil cytoplasmic antibody ; ANIT ; alpha-naphthylisothiocyanate ; BA ; bile acids ; BDL ; bile duct ligation ; BEC ; biliary epithelial cell ; CCC ; cholangiocellular carcinoma ; Cftr ; cystic fibrosis transmembrane conductance regulator ; DC ; dendritic cell ; DDC ; 3 ; 5-diethoxycarbonyl-1 ; 4-dihydrocollidine ; DSS ; dextrane sodium sulfate ; fch ; ferrochelatase ; fMLT ; N-formyl L-methionine L-leucin L-tyrosine ; GVHD ; graft-vs.-host disease ; h ; hours ; HSDH ; 3伪-hydroxyster

刊名：Journal of Hepatology

出版年：June 2014

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