作者：Felicia C. Huynh ; Daniel Nguyen ; Frank E. Jones ; ^{fjones3@tulane.edu}

关键词：EGFR-family ; Trastuzumab ; Breast cancer ; Therapeutic resistance ; S6K1 ; Rapamycin ; mTORC1

刊名：Biochemical and Biophysical Research Communications

出版年：2017

作者：Mayu Fujimoto^a ; ¹ ; Takahiro Inoue^a ; ¹ ; Hiroaki Kito^a ; Satomi Niwa^a ; Takayoshi Suzuki^b ; Katsuhiko Muraki^c ; Susumu Ohya^a ; ^{sohya@mb.kyoto-phu.ac.jp}

关键词：Breast cancer ; HER2 ; Resistance to HER2-targeted therapy ; Ca2+-activated Cl&minus ; channel ; ANO1 ; IGFBP5

刊名：Biochemical and Biophysical Research Communications

出版年：2017

作者：Ksenija Asić ^{ksenija.asic@gmail.com" class="auth_mail" title="E-mail the corresponding author}Author Vitae

关键词：Cancer therapy ; Targeted therapy ; Resistance mechanisms ; Intrinsic resistance ; Acquired resistance ; Trastuzumab

刊名：Critical Reviews in Oncology and Hematology

出版年：2016

作者：Lingfei Wang^a ; ¹ ; Xiaojie Yu^a ; ¹ ; Jian Dong^b ; ¹ ; Yanchun Meng^c ; ¹ ; Yang Yang^a ; Huajing Wang^a ; Chao Wang^a ; Yajun Zhang^a ; Yirong Zhao^a ; Jian Zhao^a ; Hao Wang^a ; ^{hwang_smmu@163.com" class="auth_mail" title="E-mail the corresponding author} ; Cuihua Lu^d ; ^{lch670608@sina.com" class="auth_mail" title="E-mail the corresponding author} ; Bohua Li^a ; ^{bohuali1020@163.com" class="auth_mail" title="E-mail the corresponding author}

关键词：Breast cancer ; Saracatinib ; Anti-ErbB2 antibody ; Cell death ; Trastuzumab resistance

刊名：Biochemical and Biophysical Research Communications

出版年：2016

作者：Prof Nadia Harbeck ; MD^a ; Prof Chiun-Sheng Huang ; MD^b ; ^c ; Sara Hurvitz ; MD^d ; ^e ; Dah-Cherng Yeh ; MD^c ; ^f ; Prof Zhimin Shao ; MD^g ; Prof Seock-Ah Im ; MD^h ; Prof Kyung Hae Jung ; MDⁱ ; Kunwei Shen ; MD^j ; Jungsil Ro ; MD^k ; Prof Jacek Jassem ; MD^l ; Prof Qingyuan Zhang ; MD^m ; Young-Hyuck Im ; MDⁿ ; Prof Marek Wojtukiewicz ; MD^o ; Qiang Sun ; MD^p ; Prof Shin-Cheh Chen ; MD^c ; ^q ; Rainer-Georg Goeldner ; PhD^r ; Martina Uttenreuther-Fischer ; MD^r ; Prof Binghe Xu ; MD^s ; ^t ; ^{bhxu@hotmail.com" class="auth_mail" title="E-mail the corresponding author} ; Martine Piccart-Gebhart ; MD^u ; on behalf of the LUX-Breast 1 study group

刊名：The Lancet Oncology

出版年：2016

作者：Mohsin Soleja ; MD ; ^{mohsinsoleja@gmail.com} ; Mothaffar F. Rimawi ; MD

关键词：Metastatic breast cancer ; HER2 ; Trastuzumab ; Pertuzumab ; T-DM1 ; Lapatinib ; Resistance ; Management ; Novel therapy

刊名：Current Problems in Cancer

出版年：2016

作者：F. Javier Carmona^a ; Filippo Montemurro^b ; Srinivasaraghavan Kannan^c ; Valentina Rossi^d ; Chandra Verma^c ; ^e ; ^f ; José ; Baselga^a ; ^g ; Maurizio Scaltriti^a ; ^{scaltrim@mskcc.org" class="auth_mail" title="E-mail the corresponding author}

关键词：PI3K ; mTOR ; Trastuzumab ; Targeted therapy ; Drug resistance ; AKT3

刊名：Pharmacology and Therapeutics

出版年：2016

作者：Elham Abu Sharieh^a ; ^b ; Abdulla S. Awidi^b ; ^c ; Mamoun Ahram^d ; Malek A. Zihlif^a ; ^{m.zihlif@ju.edu.jo" class="auth_mail" title="E-mail the corresponding author}

关键词：(ESR-A) ; estrogen receptor alpha ; (PR) ; progesterone ; (HER-2) ; human epidermal receptor 2 ; PCR ; POLYMERASE chain reaction ; (FDA) ; Food and Drug Administration ; (ATCC ; USA) ; American Type Culture Collection ; (FBS) ; fetal bovine serum ; (MTT) ; 3-(4 ; 5-dimethylthiazol-2-yl)-2 ; 5-diphenyl tetrazolium bromide ; (IC50) ; the inhibitory concentrations ; (ACTB) ; actin beta ; (GAPDH) ; beta-2-microglobulin ; glyceraldehyde-3-phosphate dehydrogenase ; (HPRT1) ; hypoxanthine phosphoribosyltransferase 1 ; (RPLP0) ; ri

刊名：Gene

出版年：2016

作者：Amanda Cañ ; as^a ; ^b ; ^{amandacanasrodriguez@gmail.com" class="auth_mail" title="E-mail the corresponding author} ; Laura M. Ló ; pez-Sá ; nchez^a ; ^b ; ^{lmlopezsanchez@gmail.com" class="auth_mail" title="E-mail the corresponding author} ; Jon Peñ ; arando^a ; ^b ; ^{jon_aries80@hotmail.com" class="auth_mail" title="E-mail the corresponding author} ; Araceli Valverde^a ; ^b ; ^{aracelivalverdeestepa@hotmail.es" class="auth_mail" title="E-mail the corresponding author} ; Francisco Conde^a ; ^b ; ^{fmcp@usal.es" class="auth_mail" title="E-mail the corresponding author} ; Vanessa Herná ; ndez^a ; ^b ; ^{vanessa-septiembre@hotmail.com" class="auth_mail" title="E-mail the corresponding author} ; Elena Fuentes^c ; ^{elena.fuentes.sspa@juntadeandalucia.es" class="auth_mail" title="E-mail the corresponding author} ; Chary Ló ; pez-Pedrera^d ; ^{rosario.lopez.exts@juntadeandalucia.es" class="auth_mail" title="E-mail the corresponding author} ; Juan R. de la Haba-Rodrí ; guez^a ; ^b ; ^{juahaba@gmail.com" class="auth_mail" title="E-mail the corresponding author} ; Enrique Aranda^a ; ^b ; ^{earandaa@seom.org" class="auth_mail" title="E-mail the corresponding author} ; Antonio Rodrí ; guez-Ariza^a ; ^b ; ^{antonio.rodriguez.exts@juntadeandalucia.es" class="auth_mail" title="E-mail the corresponding author}

关键词：Apoptosis ; Breast cancer ; S-nitrosoglutathione reductase ; HER2/neu ; Nitric oxide ; S-nitrosylation

刊名：Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease

出版年：2016

作者：Ji Young Kim^a ; ^b ; ¹ ; Youngkwan Cho^a ; ^b ; ¹ ; Eunhye Oh^a ; ^b ; Nahyun Lee^a ; ^b ; Hyunsook An^a ; ^b ; Daeil Sung^a ; ^b ; Tae-Min Cho^a ; Jae Hong Seo^a ; ^b ; ^{cancer@korea.ac.kr" class="auth_mail" title="E-mail the corresponding author}

关键词：HER2 ; p95HER2 ; Disulfiram ; ALDH1A1 ; Apoptosis ; Trastuzumab resistance

刊名：Cancer Letters

出版年：2016