搜索页_+PRC2

设为首页

收藏本站

网站地图 | English | 公务邮箱

读者指南

学术客户端

NSTL服务站

科技查新

外文资源

Wiley电子期刊(6)	NATURE电子期刊(17)	ACS电子期刊(16)
SpringerLink电子期刊(58)	Elsevier电子期刊(182)

在“Elsevier电子期刊”中，命中：182条，耗时：0.0200229 秒

在所有数据库中总计命中：279条

1.Compositional and functional diversity of canonical PRC1 complexes in mammals

作者：Katelyn E. Connelly^a ; Emily C. Dykhuizen^a ; ^b ; ^{edykhui@purdue.edu}

关键词：bps ; base pairs ; PcG ; Polycomb Group ; PRC1 ; Polycomb Repressive Complex 1 ; PRC2 ; Polycomb Repressive Complex 2 ; Pc ; Polycomb ; Ph ; Polyhomeotic ; Psc ; Posterior sex combs ; Sce ; Sex combs extra ; H3K27me3 ; histone H3 lysine 27 trimethylation ; SAM ; sterile alpha motif ; PCGF ; Polycomb Group Finger ; PHC ; human Polyhomeotic ; CBX ; chromobox homolog ; PREs ; Polycomb Response Elements ; MLL ; mixed lineage leukemia ; SWI/SNF ; Switch/sucrose non-fermentable ; PRE ; Polycomb Response Element ; ESC ; embryonic stem c

刊名：Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms

出版年：2017

2.Hotair facilitates hepatic stellate cells activation and fibrogenesis in the liver

作者：Er-Bao Bian^a ; ^b ; Yuan-Yuan Wang^a ; ^b ; Yang Yang^a ; ^b ; Bao-Ming Wu^a ; ^b ; Tao Xu^a ; ^b ; Xiao-Ming Meng^a ; ^b ; Cheng Huang^a ; ^b ; Lei Zhang^a ; ^b ; Xiong-Wen Lv^a ; ^b ; Zhi-Gang Xiong^a ; ^c ; ^{zxiong@msm.edu} ; Jun Li^a ; ^b ; ^{lj@ahmu.edu.cn}

关键词：Hotair ; LncRNA HOX transcript antisense RNA ; HSCs ; hepatic stellate cells ; PRC2 ; polycomb repressive complex 2 ; H3K27me3 ; histone H3-lysine27 ; DNMT1 ; DNA methyltransferase 1 ; α-SMA ; alpha smooth muscle actin ; Col1a1 ; alpha1(1) collagen ; NcRNA ; non-coding RNA ; MiRNAs ; microRNAs ; CeRNAs ; competing endogenous RNAs ; MEG3 ; maternally expressed gene 3 ; H&E ; haematoxylin and eosin ; MMP-2 ; matrix metallo-proteinase 2 ; EZH2 ; zeste homologue 2 ; DZNep ; 3 deazaneplanocin A ; HCC ; hepatocellular carcinoma ; HU

刊名：Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease

出版年：2017

3.The Antisense Transcript SMN-AS1 Regulates SMN Expression and Is a Novel Therapeutic Target for Spinal Muscular Atrophy

作者：Constantin d&rsquo ; Ydewalle¹ ; Daniel M. Ramos² ; Noah J. Pyles¹ ; Shi-Yan Ng³ ; ⁴ ; ⁷ ; Mariusz Gorz¹ ; Celeste M. Pilato¹ ; Karen Ling⁵ ; Lingling Kong¹ ; Amanda J. Ward⁶ ; Lee L. Rubin³ ; ⁴ ; Frank Rigo⁵ ; C. Frank Bennett⁵ ; Charlotte J. Sumner¹ ; ² ; ⁸ ; ^{csumner1@jhmi.edu}

关键词：spinal muscular atrophy ; SMN ; long non-coding RNA ; antisense oligonucleotides ; SMA therapeutics

刊名：Neuron

出版年：2017

4.Human PRE-PIK3C2B, an intronic cis-element with dual function of activation and repression

作者：Jayant Maini^a ; Mohsen Ghasemi^a ; Deepti Yandhuri^b ; Suman S. Thakur^b ; Vani Brahmachari^a ; ^{vani.brahmachari@gmail.com}

关键词：Human PRE-TRE ; MLL ; Regulation ; Polycomb and trithorax ; Chromatin interaction ; Genetic interaction

刊名：Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms

出版年：2017

5.lncRNA Functional Networks in Oligodendrocytes Reveal Stage-Specific Myelination Control by an lncOL1/Suz12 Complex in the CNS

作者：Danyang He¹ ; ² ; Jincheng Wang¹ ; ⁵ ; Yulan Lu³ ; Yaqi Deng¹ ; Chuntao Zhao¹ ; Lingli Xu¹ ; ³ ; Yinhuai Chen⁴ ; Yueh-Chiang Hu⁴ ; Wenhao Zhou³ ; Q. Richard Lu¹ ; ² ; ³ ; ⁶ ; ^{richard.lu@cchmc.org}

关键词：long noncoding RNA ; myelination ; remyelination ; chromatin remodeling ; neural precursors ; OPC ; oligodendrocyte differentiation ; functional genomics ; polycomb repressive complex ; EZH2

刊名：Neuron

出版年：2017

6.Novel 3-methylindoline inhibitors of EZH2: Design, synthesis and SAR

作者：Amantullah Ansari^a ; Sharad Satalkar^a ; Varshavekumar Patil^a ; Amit S. Shete^a ; Simranjeet Kaur^a ; Ashu Gupta^a ; Siddhartha Singh^a ; Mohd. Raja^a ; Daniel L. Severance^b ; Sebastiá ; n Bernales^c ; Sarvajit Chakravarty^c ; David T. Hung^c ; Son M. Pham^c ; Francisco J. Herrera^c ; Roopa Rai^c ; ^{roopa.rai@hotmail.com}

关键词：EZH2 ; Indoline ; Anticancer ; Methyltransferases

刊名：Bioorganic & Medicinal Chemistry Letters

出版年：2017

7.Genome-wide RNA-seq and ChIP-seq reveal Linc-YY1 function in regulating YY1/PRC2 activity during skeletal myogenesis

作者：Kun Sun^a ; ^b ; Liang Zhou^b ; Yu Zhao^b ; Huating Wang^b ; ^c ; ^{huating.wang@cuhk.edu.hk" class="auth_mail" title="E-mail the corresponding author} ; Hao Sun^a ; ^b ; ^{haosun@cuhk.edu.hk" class="auth_mail" title="E-mail the corresponding author}

关键词：Linc-YY1 ; Myogenesis ; RNA-seq ; ChIP-seq ; C2C12 cells

刊名：Genomics Data

出版年：2016

8.EpCAM-regulated intramembrane proteolysis induces a cancer stem cell-like gene signature in hepatitis B virus-infected hepatocytes

作者：Saravana Kumar Kailasam Mani¹ ; ² ; Hao Zhang¹ ; ² ; Ahmed Diab¹ ; ² ; Pete E. Pascuzzi² ; ³ ; Lydie Lefranç ; ois⁴ ; Nadim Fares⁴ ; Brigitte Bancel⁴ ; Philippe Merle⁴ ; Ourania Andrisani¹ ; ² ; ^{andrisao@purdue.edu" class="auth_mail" title="E-mail the corresponding author}

关键词：cccDNA ; circular covalently closed DNA ; EpCAM ; epithelial cell adhesion molecule ; EpICD ; EpCAM intracellular domain ; hCSCs ; hepatic cancer stem cells ; HBV ; hepatitis B virus ; HBc ; hepatitis B virus core antigen ; HCC ; hepatocellular carcinoma ; PRC2 ; polycomb repressor complex 2 ; RIP ; regulated intramembrane proteolysis

刊名：Journal of Hepatology

出版年：2016

9.Identification of novel EZH2 inhibitors through pharmacophore-based virtual screening and biological assays

作者：Yunlong Wu^a ; ^&dagger ; ; Junchi Hu^b ; ^c ; ^&dagger ; ; Hong Ding^b ; ^&dagger ; ; Limin Chen^d ; Yuanyuan Zhang^b ; Rongfeng Liu^e ; Pan Xu^b ; ^c ; Daohai Du^b ; Wenchao Lu^b ; ^c ; Jingqiu Liu^b ; Yan Liu^b ; Yu-Chih Liu^e ; Junyan Lu^b ; Jin Zhang^f ; ^{med-zhangjin@vip.sina.com" class="auth_mail" title="E-mail the corresponding author} ; Zhiyi Yao^a ; ^{yao99cn@sit.edu.cn" class="auth_mail" title="E-mail the corresponding author} ; Cheng Luo^b ; ^{cluo@simm.ac.cn" class="auth_mail" title="E-mail the corresponding author}

关键词：EZH2 ; Epigenetics ; PRC2 ; Computational drug design ; Pharmacophore-based virtual screening

刊名：Bioorganic & Medicinal Chemistry Letters

出版年：2016

10.Deletion of Polycomb Repressive Complex 2 From Mouse Intestine Causes Loss of Stem Cells

作者：Martijn A.J. Koppens¹ ; Gergana Bounova² ; Gaetano Gargiulo¹ ; Ellen Tanger¹ ; Hans Janssen³ ; Paulien Cornelissen-Steijger¹ ; Marleen Blom⁴ ; Ji-Ying Song⁵ ; Lodewyk F.A. Wessels² ; ⁶ ; ⁷ ; Maarten van Lohuizen¹ ; ⁷ ; ^{M.V.Lohuizen@NKI.NL" class="auth_mail" title="E-mail the corresponding author}

关键词：Small Intestine ; Development ; ISC ; PRC1

刊名：Gastroenterology

出版年：2016

按检索点细分(182)

题名(33)

作者(7)

关键词(34)

文摘(144)

按出版年细分(182)

2027年及以后(12)

2017年(6)

2016年(28)

2015年(10)

2013年(30)

2012年(23)

2011年(15)

2010年(19)

2009年(8)

2008年(9)

2007年(10)

2006年(2)

2005年(1)

2004年(2)

2000年及以前(7)

常见问题　|　交通位置　|　联系我们　|　OA远程办公

地址：北京市海淀区学院路29号邮编：100083

电话：办公室：(+86 10)66554848；文献借阅、咨询服务、科技查新：66554700