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Elsevier电子期刊(59)

在“Elsevier电子期刊”中，命中：59条，耗时：0.0229567 秒

在所有数据库中总计命中：84条

1.Michael acceptor containing drugs are a novel class of 5-lipoxygenase inhibitor targeting the surface cysteines C416 and C418

作者：Isabelle V. Maucherp>ap> ; Michael Rü ; hlp>ap> ; Simon B.M. Kretschmerp>ap> ; Bettina Hofmannp>ap> ; Benjamin Kü ; hnp>ap> ; Jasmin Fettelp>ap> ; Anja Vogelp>ap>p> ; p>p>bp> ; Karsten T. Flü ; gelp>ap> ; Georg Manolikakesp>cp> ; Nadine Hellmuthp>ap> ; Ann-Kathrin Hä ; fnerp>ap> ; Vahid Golghalyanip>ap> ; Ann-Katrin Ballp>ap> ; Matthias Pieschep>dp>p> ; p>p>gp> ; Carmela Matronep>dp> ; Gerd Geisslingerp>bp>p> ; p>p>ep> ; Michael J. Parnhamp>bp> ; Michael Karasp>ap> ; Dieter Steinhilberp>ap> ; Jessica Roosp>ap>p> ; p>p>1p>p> ; p>p>roos@pharmchem.uni-frankfurt.dep> ; Thorsten J. Maierp>dp>p> ; p>p>fp>p> ; p>p>1p>p> ; p>p>maier@biomed.au.dkp>

关键词：AA ; arachidonic acid ; methyl-BQ ; 2 ; 5-dimethyl-1 ; 4-benzoquinone ; CDDO ; CDDO-methylester ; methoxy-BQ ; 2 ; 3-dimethoxy-5-methyl-p-benzoquinone ; methoxy-NS ; 3-methoxy-β-nitrostyrene ; DMF ; dimethyl fumarate ; GSH ; glutathione ; OH-BQ ; 2 ; 5-dihydroxy-1 ; 4-benzoquinone ; HPLC ; high-performance liquid chromatography ; H(P)ETE ; hydro (peroxy-) eicosatetraenoic acid ; LT ; leukotrienes ; MS ; mass spectrometry ; NAC ; N-acetylcysteine ; NAPQI ; N-acetyl-p-benzoquinone imine ; NEM ; N-ethylmaleimide ; NFA ; nitro-fatty acid

刊名：Biochemical Pharmacology

出版年：2017

2.Activation of GR but not PXR by dexamethasone attenuated acetaminophen hepatotoxicities via Fgf21 induction

作者：Saurabh G. Visputep>ap> ; Pengli Bup>ap>p> ; p>p>bp> ; Yuan Lep>ap> ; Xingguo Chengp>ap>p> ; p>p>chengx@stjohns.edup>

关键词：APAP ; acetaminophen ; bp ; base pair ; ChIP ; chromatin immunoprecipitation ; Cyp ; cytochrome p450 enzyme ; DEX ; dexamethasone ; Fgf21 ; fibroblast growth factor 21 ; GR ; glucocorticoid receptor ; GRE ; glucocorticoid receptor response element ; GSH ; Glutathione ; i.p. ; intraperitoneal ; NAPQI ; N-acetyl-p-benzoquinone imine ; PGC1α ; peroxisome proliferator-activated receptor gamma coactivator protein-1α ; PPAR ; peroxisome proliferator-activated receptor ; PXR ; pregnane X receptor ; TSS ; transcription start site

刊名：Toxicology

出版年：2017

3.Acetaminophen-induced hepatotoxicity: Preventive effect of trans anethole

作者：Bruno Ambró ; sio da Rochap>ap>p> ; p>p>brunoambrosiorocha@gmail.comp> ; Alessandra M. Versuti Ritterp>bp>p> ; p>p>ale_mileni@hotmail.comp> ; Franciele Queiroz Amesp>ap>p> ; p>p>francieleames@gmail.comp> ; Odinei Hess Gonç ; alvesp>cp>p> ; p>p>odinei@utfpr.edu.brp> ; Fernanda Vitó ; ria Leimannp>cp>p> ; p>p>fernanda@utfpr.edu.brp> ; Lí ; via Brachtp>dp>p> ; p>p>liviabracht@gmail.comp> ; Maria Raquel Març ; al Natalip>ep>p> ; p>p>mrmnatali@uem.brp> ; Roberto Kenji Nakamura Cumanp>ap> ; Ciomar Ap. Bersani-Amadop>ap>p> ; p>p>cabamado@uem.brp>

关键词：Trans anethole ; Acetaminophen ; Hepatoprotection

刊名：Biomedicine & Pharmacotherapy

出版年：2017

4.Caffeic acid prevents acetaminophen-induced liver injury by activating the Keap1-Nrf2 antioxidative defense system

作者：Chun Pangp>ap>p> ; p>p>cp>p> ; p>p>1p> ; Zhiyong Zhengp>ap>p> ; p>p>1p> ; Liang Ship>ap> ; Yuchen Shengp>bp> ; Hai Weip>cp> ; Zhengtao Wangp>ap> ; Lili Jip>ap>p> ; p>p>lichenyue1307@126.com" class="auth_mail" title="E-mail the corresponding authorp>

关键词：APAP ; acetaminophen ; DILI ; drug-induced liver injury ; CA ; Caffeic acid ; ALT/AST ; alanine/aspartate aminotransferases ; MPO ; myeloperoxidase ; GSH ; glutathione ; ROS ; reactive oxygen species ; Nrf2 ; nuclear factor erythroid 2-related factor 2 ; HO-1 ; heme oxygenase 1 ; NQO1 ; NAD(P)H ; quinone oxidoreductase 1 ; ZnPP ; zinc protoporphyrin ; Dim ; diminutol ; Keap1 ; kelch-like ECH-associated protein-1 ; CYP ; cytochrome P450 ; NAPQI ; N-acetyl-p-benzoquinone imine ; NAC ; N-acetylcysteine ; H2DCFDA ; 2ʹ-7ʹ-Dichlorodih

刊名：Free Radical Biology and Medicine

出版年：2016

5.The fungicide thiabendazole causes apoptosis in rat hepatocytes

作者：Marilyne Sé ; ï ; dep>ap>p> ; p>p>bp> ; Michel Marionp>ap> ; Mircea Alexandru Mateescup>ap>p> ; p>p>dp> ; Diana A. Averill-Batesp>ap>p> ; p>p>bp>p> ; p>p>cp>p> ; p>p>dp>p> ; p>p>averill.diana@uqam.ca" class="auth_mail" title="E-mail the corresponding authorp>

关键词：APAF-1 ; apoptosis protease activating factor-1 ; CYP ; cytochrome P450 ; DISC ; death inducing signaling complex ; EROD ; ethoxyresorufin-o-deethylase ; FADD ; Fas-associated death domain ; FBS ; fetal bovine serum ; FCCP ; carbonylcyanide p-trifluoromethoxyphenylhydrazone ; GAPDH ; glyceraldehyde-3-phosphate dehydrogenase ; HRP ; horseradish peroxidase ; LDH ; lactate dehydrogenase ; MTT ; methyl tetrazolium ; NAPQI ; N-acetyl-para-benzoquinone-imine ; PI ; propidium iodide ; PROD ; pentoxyresorufin-o-dealkylase ; PVDF

刊名：Toxicology in Vitro

出版年：2016

6.Transcriptome association analysis identifies miR-375 as a major determinant of variable acetaminophen glucuronidation by human liver

作者：Ioannis Papageorgioup>ap>p> ; p>p>johnp@vetmed.wsu.edu" class="auth_mail" title="E-mail the corresponding authorp> ; Marina Freytsisp>bp>p> ; p>p>Marina.Freytsis@tufts.edu" class="auth_mail" title="E-mail the corresponding authorp> ; Michael H. Courtp>ap>p> ; p>p>michael.court@vetmed.wsu.edu" class="auth_mail" title="E-mail the corresponding authorp>

关键词：ALF ; acute liver failure ; NAPQI ; N-acetyl-p-benzoquinone imine ; UGT ; UDP-glucuronosyltransferase ; SULT ; sulfotransferase ; CYP ; cytochrome P450 ; 3&prime ; -UTR ; 3&prime ; -untranslated region ; SNP ; single nucleotide polymorphism ; miRNA ; microRNA ; UDPGA ; uridine diphosphate glucuronic acid ; qPCR ; quantitative real-time PCR ; AhR ; aryl hydrocarbon receptor ; MRE ; miRNA response element ; HNF1A ; hepatocyte nuclear factor 1-alpha ; HNF1B ; hepatocyte nuclear factor 1-beta ; Nrf2 ; nuclear factor erythroid 2-rel

刊名：Biochemical Pharmacology

出版年：2016

7.Experimental models of hepatotoxicity related to acute liver failure

作者：Michaë ; l Maesp>ap> ; Mathieu Vinkenp>ap>p> ; p>p>1p>p> ; p>p>mvinken@vub.ac.be" class="auth_mail" title="E-mail the corresponding authorp> ; Hartmut Jaeschkep>bp>p> ; p>p>1p>

关键词：ALT ; alanine aminotransferase ; APAP ; acetaminophen ; ConA ; concanavalin A ; CYP ; cytochrome P450 ; ET ; endotoxin ; FasL ; Fas ligand ; Gal ; D-galactosamine ; GSH ; glutathione ; IFNγ ; interferon γ ; NAPQI ; N-acetyl-p-benzoquinone imine ; p-JNK ; c-jun N-terminal kinase activation ; TNFα ; tumor necrosis factor α

刊名：Toxicology and Applied Pharmacology

出版年：2016

8.Intravenous Paracetamol Decreases Requirements of Morphine in Very Preterm Infants

作者：Antti Hä ; rmä ; MDp>1p>p> ; p>p>2p> ; Outi Aikio ; MD ; PhDp>1p>p> ; p>p>2p>p> ; p>p>outi.aikio@ppshp.fi" class="auth_mail" title="E-mail the corresponding authorp> ; Mikko Hallman ; MD ; PhDp>1p>p> ; p>p>2p> ; Timo Saarela ; MD ; PhDp>1p>p> ; p>p>2p>

关键词：CYP ; Cytochrome P450 ; NAPQI ; N-acetyl-p-benzoquinone imine ; NEC ; Necrotizing enterocolitis ; NIAPAS ; Neonatal Infant Acute Pain Assessment Scale ; NICU ; Neonatal intensive care unit ; PDA ; Patent ductus arteriosus ; VLGA ; Very low gestational age

刊名：The Journal of Pediatrics

出版年：2016

9.Involvement of connexin43 in acetaminophen-induced liver injury

作者：Michaë ; l Maesp>ap> ; Mitchell R. McGillp>bp>p> ; p>p>1p> ; Tereza Cristina da Silvap>cp> ; Chloé ; Abelsp>dp>p> ; p>p>ep> ; Margitta Lebofskyp>bp> ; Cintia Maria Monteiro de Araú ; jop>cp> ; Taynã ; Tiburciop>cp> ; Isabel Veloso Alves Pereirap>cp> ; Joost Willebrordsp>ap> ; Sara Crespo Yanguasp>ap> ; Anwar Farhoodp>fp> ; Alain Beschinp>dp>p> ; p>p>ep> ; Jo A. Van Ginderachterp>dp>p> ; p>p>ep> ; Maria Lucia Zaidan Daglip>cp> ; Hartmut Jaeschkep>bp> ; Bruno Cogliatip>cp>p> ; p>p>2p> ; Mathieu Vinkenp>ap>p> ; p>p>2p>p> ; p>p>mvinken@vub.ac.be" class="auth_mail" title="E-mail the corresponding authorp>

关键词：ALT ; alanine aminotransferase ; APAP ; acetaminophen ; CD ; cluster of differentiation ; Cx ; connexin ; ELISA ; enzyme-linked immunosorbent assay ; GJIC ; gap junctional intercellular communication ; GSH ; glutathione ; GSSG ; glutathione disulfide ; hepaCAM ; hepatocyte cell adhesion molecule ; IFNγ ; interferon γ ; IL-1β/6/10 ; interleukin 1β/6/10 ; n ; number of repeats ; NAPQI ; N-acetyl-p-benzoquinone imine ; p ; probability ; RT-qPCR ; reverse transcription quantitative real-time polymerase chain reaction ; SEM ; stan

刊名：Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease

出版年：2016

10.Role of nicotinamide (vitamin B3) in acetaminophen-induced changes in rat liver: Nicotinamide effect in acetaminophen-damged liver

作者：Yomna I. Mahmoudp> ; p>p>yomna_ia@yahoo.com" class="auth_mail" title="E-mail the corresponding authorp>p> ; p>p>yomnaia@yahoo.com" class="auth_mail" title="E-mail the corresponding authorp> ; Asmaa A. Mahmoud

关键词：2PY ; N-methyl-2-pyridone-5-carboxamide ; 4PY ; N-methyl-4-pyridone-5-carboxamide ; AIF ; apoptosis inducing factor ; ALP ; alkaline phosphatase ; ALT ; alanine transaminase ; APAP ; acetaminophen ; AST ; aspartate aminotransferase ; BUN ; blood urea nitrogen ; GPx ; glutathione peroxidase ; GSH ; reduced glutathione ; MDA ; malondialdehyde ; NAD+ ; nicotinamide adenine dinucleotide ; NADP+ ; nicotinamide adenine dinucleotide phosphate ; NAM ; nicotinamide ; NAPQI ; N-acetyl-p-benzoquinone imine ; PARP ; poly (adenosine dipho

刊名：Experimental and Toxicologic Pathology

出版年：2016

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