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Elsevier电子期刊(778)

在“Elsevier电子期刊”中，命中：778条，耗时：0.0119944 秒

在所有数据库中总计命中：778条

1.C-terminally truncated constitutively active androgen receptor variants and their biologic and clinical significance in castration-resistant prostate cancer

作者：Anca Azoitei^a ; Axel S. Merseburger^b ; Beate Godau^b ; M. Raschid Hoda^b ; Evi Schmid^c ; Marcus V. Cronauer^b ; ^{marcus.cronauer@uksh.de}

关键词：aa ; amino-acids ; ADT ; androgen deprivation therapy ; AR ; androgen receptor ; ARΔLBD ; androgen receptor lacking a functional ligand binding domain ; AR-V ; AR splice variant ; BET ; bromodomain and extra-terminal ; CE ; cryptic exon ; CRPC ; castration-resistant prostate cancer ; CTC ; circulating tumor cell ; CTD ; carboxy-terminal domain ; DBD ; DNA-binding domain ; EMT ; epithelial-mesenchymal transition ; FFPE ; formalin-fixed paraffin-embedded ; HR ; hinge region ; I ; intron ; IF ; immunofluorescence ; IGF-1 ; insulin

刊名：The Journal of Steroid Biochemistry and Molecular Biology

出版年：2017

2.Protein engineering of aldolase LbDERA for enhanced activity toward real substrates with a high-throughput screening method coupled with an aldehyde dehydrogenase

作者：Xue-Cheng Jiao ; Jiang Pan ; ^{panjiang@ecust.edu.cn} ; Xu-Dong Kong ; Jian-He Xu ; ^{jianhexu@ecust.edu.cn}

关键词：Aldehyde dehydrogenase ; Crystal structure ; 2-Deoxyribose-5-phosphate aldolase ; High-throughput screening ; Protein engineering ; Statin side chains

刊名：Biochemical and Biophysical Research Communications

出版年：2017

3.SRC2-3 binds to vitamin D receptor with high sensitivity and strong affinity

作者：Daichi Egawa ; Toshimasa Itoh ; Akira Kato ; Saori Kataoka ; Yasuaki Anami ; Keiko Yamamoto ; ^{yamamoto@ac.shoyaku.ac.jp}

关键词：VDR ; vitamin D receptor ; LBD ; ligand-binding domain ; DRIP ; vitamin D receptor interacting protein ; SRC ; steroid receptor coactivator ; SPR ; surface plasmon resonance ; AF2 ; activation-function 2

刊名：Bioorganic & Medicinal Chemistry

出版年：2017

4.Synthesis of novel steroidal agonists, partial agonists, and antagonists for the glucocorticoid receptor

作者：Zhuang Jin^a ; Hua Lin^a ; Sathish Srinivasan^b ; Jerome C. Nwachukwu^b ; Nelson Bruno^b ; Patrick R. Griffin^a ; Kendall W. Nettles^b ; ; Theodore M. Kamenecka^a ; ^{kameneck@scripps.edu}

关键词：AF-1 ; activation function-1 ; AF-2 ; activation function-2 ; AP-1 ; activator protein 1 ; dppp ; 1 ; 3-bis(diphenylphosphino)propane ; DEX ; dexamethasone ; DIEA ; N ; N-diisopropylethylamine ; FKBP5 ; FK506-binding protein 5 ; GR ; glucocorticoid receptor ; GRE ; glucocorticoid-response element ; HATU ; 1-[bis(dimethylamino)methylene]-1H-12 ; 3-triazolo[4 ; 5-b]pyridinium 3-oxid hexafluorophosphate ; IL-6 ; Interleukin-6 ; LBD ; ligand-binding domain ; LPS ; lipopolysaccharide ; MMTV ; mouse mammary tumor virus ; NF-κB ; nuclear

刊名：Bioorganic & Medicinal Chemistry Letters

出版年：2017

5.Lessons from tissue compartment-specific analysis of androgen receptor alterations in prostate cancer

作者：Mark Daniel^a ; ^b ; Scott M. Dehm^b ; ^c ; ^d ; ^dehm@umn.edu

关键词：LHRH ; luteinizing hormone releasing hormone ; ADT ; androgen depletion therapy ; CRPC ; castration-resistant prostate cancer ; CYP17 ; cytochrome P450 c17 ; MR ; mineralocorticoid receptor ; ER ; estrogen receptor ; PR ; progestins receptor ; GR ; glucocorticoid receptor ; NTD ; NH2-terminal domain ; AF-1 ; activation function 1 ; LBD ; ligand bind domain ; ARE ; androgen response element ; RIP ; RNA co-immunoprecipitation ; NCOA ; nuclear receptor coactivator ; NCOR ; nuclear receptor corepressor ; CTC ; circulating tumor c

刊名：The Journal of Steroid Biochemistry and Molecular Biology

出版年：2017

6.In silico selection and cell-based characterization of selective and bioactive compounds for androgen-dependent prostate cancer cell

作者：Elisa C. Santa Cruz ; Adriel R. Carecho ; Marta E. Saidel ; Carlos Alberto Montanari ; Andrei Leitã ; o ; ^{andleitao@iqsc.usp.br}

关键词：ADT ; androgen deprivation therapy ; AR ; androgen receptor ; LBD ; ligand binding domain ; PCa ; prostate cancer ; SARM ; selective androgen receptor modulator ; VS ; virtual screening ; SBVS ; structure-based virtual screening ; WCRF ; World Cancer Research Fund International

刊名：Bioorganic & Medicinal Chemistry Letters

出版年：2017

7.Novel screening system for high-affinity ligand of heredity vitamin D-resistant rickets-associated vitamin D receptor mutant R274L using bioluminescent sensor

作者：Hiroki Mano^a ; Miyu Nishikawa^a ; ^b ; Kaori Yasuda^a ; Shinichi Ikushiro^a ; Nozomi Saito^c ; ¹ ; Daisuke Sawada^c ; ² ; Shinobu Honzawa^c ; ³ ; Masashi Takano^c ; Atsushi Kittaka^c ; Toshiyuki Sakaki^a ; ^b ; ^{tsakaki@pu-toyama.ac.jp}

关键词：VDR ; vitamin D receptor ; RXRα ; retinoid X receptor α ; LBD ; ligand binding domain ; VDRE ; vitamin D responsive element ; LucN ; N-terminal domain of luciferase ; LucC ; C-terminal domain of luciferase

刊名：The Journal of Steroid Biochemistry and Molecular Biology

出版年：2017

8.Acetylated deoxycholic (DCA) and cholic (CA) acids are potent ligands of pregnane X (PXR) receptor

作者：Alejandro Carazo^a ; Lucie Hyrsova^a ; Jan Dusek^a ; Hana Chodounska^b ; Alzbeta Horvatova^a ; Karel Berka^c ; Vaclav Bazgier^c ; Hongying Gan-Schreier^d ; Waleé ; Chamulitrat^d ; Eva Kudova^b ; Petr Pavek^a ; ^{petr.pavek@faf.cuni.cz}

关键词：BA ; bile acid ; CA ; cholic acid ; CDCA ; chenodeoxycholic acid ; CYP ; cytochrome P450 ; DCA ; deoxycholic acid ; 6-ECDCA ; 6α-ethyl-chenodeoxycholic acid ; obeticholic acid ; FXR ; farnesoid X receptor ; LBD ; ligand binding domain ; LCA ; lithocholic acid ; PXR ; pregnane X receptor ; TR-FRET ; time-resolved fluorescence energy transfer ; VDR ; vitamin D receptor

刊名：Toxicology Letters

出版年：2017

9.In vivo and in silico studies to identify mechanisms associated with Nurr1 modulation following early life exposure to permethrin in rats

作者：Donatella Fedeli^a ; ^&dagger ; ; Maura Montani^b ; ^&dagger ; ; Laura Bordoni^c ; Roberta Galeazzi^d ; Cinzia Nasuti^a ; Luí ; sa Correia-Sá ; ^e ; Valentina F. Domingues^e ; Maini Jayant^f ; Vani Brahmachari^f ; Luca Massaccesi^d ; Emiliano Laudadio^d ; Rosita Gabbianelli^a ; ^{rosita.gabbianelli@unicam.it}

关键词：3-PBA ; 3-phenoxybenzoic acid ; BBB ; blood&ndash ; brain barrier ; DNMTs ; DNA methyltransferases ; EDTA ; ethylenediaminetetraacetic acid ; LBD ; Ligand Binding Domain ; MSP ; Methylation-Specific PCR ; NOAEL ; No Observed Adverse Effect Level ; NuIP ; Nurr1-interacting protein ; PBS ; phosphate buffered saline ; PBS-T ; PBS containing 0.05% Tween 20 ; PD ; Parkinson&rsquo ; s disease ; PERM ; permethrin ; TH ; tyrosine hydroxylase

刊名：Neuroscience

出版年：2017

10.Assessment of cell viability and permeation enhancement in presence of lipid-based self-emulsifying drug delivery systems using Caco-2 cell model: Polysorbate 80 as the surfactant

作者：Pengli Bu^a ; ^b ; Yue Ji^b ; Silpa Narayanan^a ; Damon Dalrymple^c ; Xingguo Cheng^a ; Abu T.M. Serajuddin^a ; ^{serajuda@stjohns.edu}

关键词：LBDDS ; lipid-based drug delivery system ; LBSEDDS ; lipid-based self-emulsifying drug delivery system ; SEDDS ; self-emulsifying drug delivery system ; SMEDDS ; self-microemulsifying drug delivery system ; MTT ; 3-(4 ; 5-dimethylthiazol-2-yl)-2 ; 5-diphenyltetrazolium bromide ; PG ; propylene glycol ; HBSS ; Hank's Balanced Salt Solution ; DMEM ; Dulbecco's Modification of Eagle's Medium ; FBS ; fetal bovine serum ; DMSO ; dimethyl sulfoxide ; TEER ; transepithelial electrical resistance

刊名：European Journal of Pharmaceutical Sciences

出版年：2017

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