地震创伤后应激障碍人群白龙解郁颗粒干预分析
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摘要
目的研究中药白龙解郁颗粒对震后灾民创伤后应激障碍(post traumatic stress disorder,PTSD)的治疗作用。方法对诊断为PTSD阳性患者给予中药白龙解郁颗粒免煎剂口服,运用治疗前后灾民症状自评量表90(SCL-90)得分评价干预效果。结果震后灾民的躯体化、强迫、抑郁、焦虑、敌对、恐怖因子分分别为(1.93±0.92),(2.04±0.92),(1.89±0.97),(1.83±1.02),(1.67±0.93),(1.57±0.96)分,明显高于中国正常人常模(P<0.05);人际关系敏感分为(1.59±0.96)分,低于中国正常人常模(P<0.05);治疗后躯体化、强迫、抑郁、焦虑、敌对、恐怖因子分分别为(1.34±0.45),(1.69±0.61),(1.57±0.61),(1.42±0.43),(1.50±0.57),(1.33±0.47)分,均较治疗前明显下降(P<0.05)。结论震后灾民的PTSD发生率较高,心理问题较为突出,白龙解郁颗粒对震后灾民的PTSD有一定疗效。
Objective To research the effect of Bailong Jieyu granules on victims of Wenchuan earthquake disaster with post-traumatic stress disorder(PTSD).Methods The victims who were diagnosed as PTSD were administrated with Bailong Jieyu granules.The efficacy was evaluated with Symptom Checklist-90(SCL-90).Results The SCL-90 scores of somatization,compulsion,depression,anxiety,hostility,phobic factors were 1.93±0.92,2.04±0.92,1.89±0.97,1.83±1.02,1.67±0.93,1.57±0.96,respectively,which were higher than those of Chinese norm;while the score of interpersonal sensitivity factor(1.59±0.96) was lower than that of Chinese norm(P<0.05).After the treatment,scores of somatization(1.34±0.45),compulsion(1.69±0.61),depression(1.57±0.61),anxiety(1.42±0.43),hostility(1.50±0.57),phobic factors(1.33±0.47) were lower than those of before the treatment(P<0.05 for all).ConclusionThe earthquake victims had high incidence of PTSD and suffered from serious psychological problem.Bailong Jieyu granule has good effect on earthquake victims with PTSD.
Objective To research the effect of Bailong Jieyu granules on victims of Wenchuan earthquake disaster with post-traumatic stress disorder(PTSD).Methods The victims who were diagnosed as PTSD were administrated with Bailong Jieyu granules.The efficacy was evaluated with Symptom Checklist-90(SCL-90).Results The SCL-90 scores of somatization,compulsion,depression,anxiety,hostility,phobic factors were 1.93±0.92,2.04±0.92,1.89±0.97,1.83±1.02,1.67±0.93,1.57±0.96,respectively,which were higher than those of Chinese norm;while the score of interpersonal sensitivity factor(1.59±0.96) was lower than that of Chinese norm(P<0.05).After the treatment,scores of somatization(1.34±0.45),compulsion(1.69±0.61),depression(1.57±0.61),anxiety(1.42±0.43),hostility(1.50±0.57),phobic factors(1.33±0.47) were lower than those of before the treatment(P<0.05 for all).ConclusionThe earthquake victims had high incidence of PTSD and suffered from serious psychological problem.Bailong Jieyu granule has good effect on earthquake victims with PTSD.
引文
[1]高雪屏,罗兴伟.汶川地震后1月内脱离/未脱离震区的亲历者PTSD筛查阳性的发生及心理影响因素[J].中南大学学报,2009,34(6):504-509.
[2]杨玉兴,魏品康,修丽娟,等.白龙解郁颗粒对67例肿瘤相关性抑郁患者生活质量的影响[J].中国中医药信息,2009,36(5):35-37.
[3]修丽娟,魏品康,刘龙,等.消痰解郁方对慢性强迫游泳应激后小鼠海马5-HT1A受体mRNA表达的影响[J].第二军医大学学报,2007,28(10):1126-1128.
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[7]李铁钢,王鸣,袁俊,等.地震灾后居住帐篷居民性生活状况与焦虑关系[J].中国公共卫生,2008,24(10):1154-1155.
[8]黄英.地震灾害后护理工作作用探讨[J].中国公共卫生,2008,24(10):1159-1160.
[9]秦虹云,季建林.PTSD及其危机干预[J].中国心理卫生杂志,2003,17(9):614-616.
[2]杨玉兴,魏品康,修丽娟,等.白龙解郁颗粒对67例肿瘤相关性抑郁患者生活质量的影响[J].中国中医药信息,2009,36(5):35-37.
[3]修丽娟,魏品康,刘龙,等.消痰解郁方对慢性强迫游泳应激后小鼠海马5-HT1A受体mRNA表达的影响[J].第二军医大学学报,2007,28(10):1126-1128.
[4]中华医学会精神科分会.中国精神障碍分类与诊断标准(CCMD-3)[M].3版.济南:山东科学技术出版社,2001:83-91.
[5]中国行为医学科学编辑委员会.行为医学量表手册[M]//吴文源.症状自评量表.北京:中华医学电子音像出版社,2005:64-67.
[6]金华,吴文源,张明园.中国正常人SCL-90评定结果的初步分析[J].中国神经精神疾病杂志,1986,12:260-263.
[7]李铁钢,王鸣,袁俊,等.地震灾后居住帐篷居民性生活状况与焦虑关系[J].中国公共卫生,2008,24(10):1154-1155.
[8]黄英.地震灾害后护理工作作用探讨[J].中国公共卫生,2008,24(10):1159-1160.
[9]秦虹云,季建林.PTSD及其危机干预[J].中国心理卫生杂志,2003,17(9):614-616.
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