广西青狮潭水库水体喹诺酮类抗生素的分布特征及生态风险评价
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摘要
利用高效液相色谱法对桂林市青狮潭水库喹诺酮类抗生素(氧氟沙星(OFX)、诺氟沙星(NOR)、环丙沙星(CIP)、恩诺沙星(ENR))进行监测,并分析其污染来源和生态风险.结果表明:青狮潭水库水体中氧氟沙星、诺氟沙星、环丙沙星和恩诺沙星的检出浓度范围分别为50.00～660.13、3.70～5.00、3.49～6.22和4.59～6.06 ng/L;与国内河流抗生素浓度水平相比,青狮潭水库水体中喹诺酮类抗生素浓度处于中等偏低水平;青狮潭水库水体喹诺酮类抗生素浓度与水体理化性质的相关性分析表明:NOR浓度与pH相关性极显著、与浊度相关性显著,CIP浓度与总磷浓度相关性显著,OFX和ENR浓度与理化指标无显著相关性;生态风险评价结果表明青狮潭水库东湖区、西湖区水体中OFX存在高风险,NOR、CIP与ENR处于中等风险水平.
The residues of quinolone antibiotics-ofloxacin( OFX),norfloxacin( NOR),ciprofloxacin( CIP) and enrofloxacin( ENR) in Qingshitan Reservoir were detected by high performance liquid chromatography( HPLC). Correlation between the concentrations of antibiotics and physical-chemical properties of water was analyzed,and ecological risk was evaluated by risk quotient method as well. The results showed that the ranges of OFX,NOR,CIP and ENR in Qingshitan Reservoir were 50.00-660.13,3.70-5.00,3.49-6.22 and 4.59-6.06 ng/L,which were at the medium level or slightly lower level comparing with the concentrations of antibiotics in domestic rivers. The NOR concentration was significantly correlated with pH and turbidity,and the CIP concentration was significantly correlated with total phosphorus( TP) concentration. While there was no significant correlation between OFX and ENR concentration and all other physicochemical indicators of water. The ecological risk assessment showed that OFX had posed a high risk in the western and eastern areas of Qingshitan Reservoir,while NOR,CIP and ENR were found to pose a moderate risk.
The residues of quinolone antibiotics-ofloxacin( OFX),norfloxacin( NOR),ciprofloxacin( CIP) and enrofloxacin( ENR) in Qingshitan Reservoir were detected by high performance liquid chromatography( HPLC). Correlation between the concentrations of antibiotics and physical-chemical properties of water was analyzed,and ecological risk was evaluated by risk quotient method as well. The results showed that the ranges of OFX,NOR,CIP and ENR in Qingshitan Reservoir were 50.00-660.13,3.70-5.00,3.49-6.22 and 4.59-6.06 ng/L,which were at the medium level or slightly lower level comparing with the concentrations of antibiotics in domestic rivers. The NOR concentration was significantly correlated with pH and turbidity,and the CIP concentration was significantly correlated with total phosphorus( TP) concentration. While there was no significant correlation between OFX and ENR concentration and all other physicochemical indicators of water. The ecological risk assessment showed that OFX had posed a high risk in the western and eastern areas of Qingshitan Reservoir,while NOR,CIP and ENR were found to pose a moderate risk.
引文
[1] Richardson BJ,Larn PKS,Martin M. Emerging chemicals of concern:Pharmaceuticals and personal care products(PPCPs)in Asia,with particular reference to Southern China.Marine Pollution Bulletin,2005,50(9):913-920.
[2] Zhang QQ,Ying GG,Pan CG et al. Comprehensive evaluation of antibiotics emission and fate in the river basins of China:source analysis,multimedia modeling,and linkage to bacterial resistance. Environmental Science&Technology,2015,49(11):6772-6782.
[3] Zhao TH,Chen YH,Han W et al. The contamination characteristics and ecological risk assessment of typical antibiotics in the upper reaches of the Dongjiang River. Ecology and Environmental Sciences,2016,25(10):1707-1713.[赵腾辉,陈奕涵,韩巍等.东江上游典型抗生素污染特征及生态风险评价.生态环境学报,2016,25(10):1707-1713.]
[4] Backhaus T,Scholze M,Grimme LH. The single substance and mixture toxicity of quinolones to the bioluminescent bacterium Vibrio fischeri. Aquatic Toxicology,2000,49(1):49-61.
[5] Hirsch R,Ternes T,Haberer K et al. Occurrence of antibiotics in the aquatic environment. Science of the Total Environment,1999,225(1/2):109-118.
[6] Zhou QX,Luo Y,Wang ME. Environmental residues and ecotoxicity of antibiotics and their resistance gene pollution:A review. Asian Journal of Ecotoxicology,2007,2(3):243-251.[周启星,罗义,王美娥.抗生素的环境残留、生态毒性及抗性基因污染.生态毒理学报,2007,2(3):243-251.]
[7] Zhang RJ,Zhang G,Zheng Q et al. Concentrations and spatial distributions of selected quinolones antibiotics in Laizhou Bay and main rivers flowing into the bay. Marine Environmental Science,2012,31(1):53-57.[张瑞杰,张干,郑芊等.喹诺酮类抗生素在莱州湾及主要入海河流中的含量和分布特征.海洋环境科学,2012,31(1):53-57.]
[8] Li J,Zhang RJ,Wang RM et al. Distribution characteristics and ecological risk assessment of antibiotic pollution in Xiaoqing River watershed. Journal of Agro-Environment Science,2016,35(7):1384-1391. DOI:10.11654/jaes.2016.07.022.[李嘉,张瑞杰,王润梅等.小清河流域抗生素污染分布特征与生态风险评估.农业环境科学学报,2016,35(7):1384-1391.]
[9] Baquero F,Martínez JL,Cantón R. Antibiotics and antibiotic resistance in water environments. Current Opinion in Biotechnology,2008,19(3):260-265.
[10] Crane M,Watts C,Boucard T. Chronic aquatic environmental risks from exposure to human pharmaceuticals. Science of the Total Environment,2006,367(1):23-41.
[11] Li Y,Jiang TT,Jing LF et al. Characteristics of residual organic pesticides and antibiotics in reservoirs of Zhoushan Islands and potential risk evaluation. Water Resources Protection,2014,30(3):31-37.[李勇,蒋婷婷,景龙飞等.舟山岛水库有机农药和抗生素残留特征及潜在风险评估.水资源保护,2014,30(3):31-37.]
[12] Feng L,Cheng YR,Feng L et al. Distribution of typical antibiotics and ecological risk assessment in main waters of Three Gorges Reservoir Area. Research of Environmental Sciences,2017,30(7):1031-1040.[封丽,程艳茹,封雷等.三峡库区主要水域典型抗生素分布及生态风险评估.环境科学研究,2017,30(7):1031-1040.]
[13] Zhu TT,Song ZH,Duan BB et al. Research on pollution and health risk by antibiotics in source water of Shiyan Reservoir in Shenzhen. Journal of Environment and Health,2013,30(11):1003-1006.[朱婷婷,宋战锋,段标标等.深圳石岩水库抗生素污染特征与健康风险初步评价.环境与健康杂志,2013,30(11):1003-1006.]
[14] Lu C,Zhang J,Wang Z et al. Determination and risk assessment of chloramphenicols in Panjiakou Reservoir,Hebei Province. China Environmental Science,2016,36(6):1843-1849.[卢诚,张俊,王钊等.河北潘家口水库氯霉素类抗生素检测及风险评估.中国环境科学,2016,36(6):1843-1849.]
[15] Liu XH,Lu SY. Occurrence and ecological risk of typical antibiotics in surface water of the Datong Lake,China. China Environmental Science,2018,38(1):320-329.[刘晓晖,卢少勇.大通湖表层水体中抗生素赋存特征与风险.中国环境科学,2018,38(1):320-329.]
[16] Tang J,Zha XX,Wang CC et al. Analysis of status of antibiotic residues in Lake Chaohu∥China Association for Science and Technology ed. Lake Basin Ecological Construction and Sustainable Development-Proceedings of the Second ChinaLake Forum. Changsha:Hunan People’s Press,2012:289-297.[唐俊,查欣欣,王晨晨等.巢湖湖水中抗生素残留现状分析∥中国科学技术协会.湖泊流域生态建设与可持续发展-第二届中国湖泊论坛论文集.长沙:湖南人民出版社,2012:289-297.]
[17] Jiang L,Hu XL,Yin DQ et al. Occurrence,distribution and seasonal variation of antibiotics in the Huangpu River,Shanghai,China. Chemosphere,2011,82(6):822-828.
[18] Wu XY,Zou H,Zhu R et al. Occurrence,distribution and ecological risk of antibiotics in surface water of the Gonghu Bay,Taihu Lake. Environmental Science,2016,37(12):4596-4604. DOI:10.13227/j. hjkx.201603005.[武旭跃,邹华,朱荣等.太湖贡湖湾水域抗生素污染特征分析与生态风险评价.环境科学,2016,37(12):4596-4604.]
[19] Liang X,Chen B,Nie X et al. The distribution and partitioning of common antibiotics in water and sediment of the Pearl River Estuary,South China. Chemosphere,2013,92(11):1410-1416.
[20] Minh TB,Leung HW,Loi HI et al. Antibiotics in the Hong Kong metropolitan area:Ubiquitous distribution and fate in Victoria Harbour. Marine Pollution Bulletin,2009,58(7):1052-1062.
[21] Chen L,Qian JP,Zhang L et al. Investigation and evaluation of water quality of blue lion tam reservoir in Guilin city.Journal of Guangxi Agriculture,2013,40(5):160-164.[陈磊,钱建平,张力等.桂林市青狮潭水库水质现状调查与评价.广东农业科学,2013,40(5):160-164.]
[22] Zheng YL,Han PL,Dai JF et al. Change of inflow runoff into the Qingshitan Reservoir in Guilin City. Water Conservancy Science and Technology and Economy,2012,18(8):46-48.[郑玉林,韩培丽,代俊峰等.桂林市青狮潭水库入库径流变化分析.水利科技与经济,2012,18(8):46-48.]
[23] Liang YP,Chen GN,Zeng HH et al. Characteristics and risk assessment of organochlorine pesticide residues in surface sediments collected at the Qingshitan Reservoir. Toxicological&Environmental Chemistry,2016,98(5/6):658-668.
[24] Yan YN,Cheng YP,Kang P et al. Pollution characteristics and potential ecological risk assessment of heavy metals in sediments of Qingshitan Reservoir. Yangtze River,2017,48(10):24-29.[闫雅妮,程亚平,康平等.青狮潭水库底泥重金属污染特征及潜在生态风险.人民长江,2017,48(10):24-29.]
[25] Kalff J,Gu BH,Liu ZW et al eds. Limnology:Inland water ecosystems. Beijing:Higher Education Press,2011.[Kalff J,古滨河,刘正文等.湖沼学:内陆水生态系统.北京:高等教育出版社,2011.]
[26] Miu ZL,Zong FS,Jiang YP eds. Study on Hydrographic Karst and Tourism Resources in Guilin. Wuhan:China University of Geosciences Press,2004.[缪钟灵,宗凤书,蒋亚萍.桂林水文岩溶及旅游资源研究.武汉:中国地质大学出版社,2004.]
[27] Qi SS,Yang X. Study on Ecological restoration mode of reservoir eutrophication by fish cage culture-case study of Qingshitan Reservoir. Environmental Science and Management,2012,37(11):151-154.[齐姗姗,杨雄.水库网箱养鱼富营养化生态修复模式研究——以青狮潭水库为例.环境科学与管理,2012,37(11):151-154.]
[28] Yu SL ed. HPLC method and application. Beijing:Chemical Industry Press,2005.[于世林.高效液相色谱方法及应用.北京:化学工业出版社,2005.]
[29] Dang G. Fluoremetric methods for the determination of Quinolones and studies on the interaction of Quinolones with metalions and bovine serum albumin[Dissertation].Hohhot:Inner Mongolia University,2005.[代钢.喹诺酮类药物的荧光分析方法及其与金属离子生物大分子作用的研究[学位论文].呼和浩特:内蒙古大学,2005.]
[30] Ding HJ,Zhong JY,Wu YX et al. Characteristics and ecological risk assessment of antibiotics in five city lakes in Nanchang City,Lake Poyang Catchment. J Lake Sci,2017,29(4):848-858. DOI:10.18307/2017.0408.[丁惠君,钟家有,吴亦潇等.鄱阳湖流域南昌市城市湖泊水体抗生素污染特征及生态风险分析.湖泊科学,2017,29(4):848-858.]
[31] Fang LF. Pollution characteristics and ecological risk assessment of typical antibiotics in the upper Huangpu River[Dissertation]. Shanghai:Donghua University,2016.[方龙飞.黄浦江上游典型抗生素污染特征及生态风险评估[学位论文].上海:东华大学,2016.]
[32] Hokstad P,Steiro T. Overall strategy for risk evaluation and priority setting of risk regulations. Radioisotopes,1985,91(1):100-111.
[33] Guérit I,BocquenéG,James A et al. Environmental risk assessment:a critical approach of the European TGD in an in situ application. Ecotoxicology&Environmental Safety,2008,71(1):291-300.
[34] Zhu TT,Duan BB,Song ZF et al. Pollution characteristics and ecological risk assessment of antibiotics in Tiegang Reser-voir in Shenzhen. Ecology and Environmental Sciences,2014,23(7):1175-1180.[朱婷婷,段标标,宋战锋等.深圳铁岗水库水体中抗生素污染特征分析及生态风险评价.生态环境学报,2014,23(7):1175-1180.]
[35] Qin YW,Zhang L,Shi Y et al. Contamination characteristics and ecological risk assessment of typical antibiotics in surface water of the Daliao River,China. Research of Environmental Sciences,2015,28(3):361-368.[秦延文,张雷,时瑶等.大辽河表层水体典型抗生素污染特征与生态风险评价.环境科学研究,2015,28(3):361-368.]
[36] Zou S,Xu W,Zhang R et al. Occurrence and distribution of antibiotics in coastal water of the Bohai Bay,China:Impacts of river discharge and aquaculture activities. Environmental Pollution,2011,159(10):2913-2920.
[37] Luo Y,Xu L,Rysz M et al. Occurrence and transport of tetracycline,sulfonamide,quinolone,and macrolide antibiotics in the Haihe River Basin,China. Environmental Science&Technology,2011,45(5):1827-1833.
[38] Li W,Shi Y,Gao L et al. Occurrence of antibiotics in water,sediments,aquatic plants,and animals from Baiyangdian Lake in North China. Chemosphere,2012,89(11):1307-1315.
[39] Zhang R,Zhang G,Zheng Q et al. Occurrence and risks of antibiotics in the Laizhou Bay,China:impacts of river discharge. Ecotoxicology&Environmental Safety,2012,80(2):208-215.
[40] Hernando MD,Mezcua M,Fernández-Alba AR et al. Environmental risk assessment of pharmaceutical residues in wastewater effluents,surface waters and sediments. Talanta,2006,69(2):334-342.
[41] Ma Y,Li M,Wu M et al. Occurrences and regional distributions of 20 antibiotics in water bodies during groundwater recharge. Science of the Total Environment,2015,518/519:498-506.
[42] Chang X,Meyer MT,Liu X et al. Determination of antibiotics in sewage from hospitals,nursery and slaughter house,wastewater treatment plant and source water in Chongqing region of Three Gorge Reservoir in China. Environmental Pollution,2010,158(5):1444-1450.
[43] Brown KD,Kulis J,Thomson B et al. Occurrence of antibiotics in hospital,residential,and dairy effluent,municipal wastewater,and the Rio Grande in New Mexico. Science of the Total Environment,2006,366(2/3):772-783.
[44] Guo XY,Wang N,Xu J et al. Research progress on environmental exposure levels and environmental fate of veterinary antibiotics. Environmental Science&Technology,2014,37(9):76-89.[郭欣妍,王娜,许静等.兽药抗生素的环境暴露水平及其环境归趋研究进展.环境科学与技术,2014,37(9):76-89.]
[45] Li J,Liu SJ. Advances in researching into the transformation and effects of antibiotics in an organic fertilizer-soil-crop systems.Acta Agriculturae Shanghai,2013,29(4):128-131.[李洁,刘善江.抗生素在有机肥料-土壤-农作物系统中的转化及影响的研究进展.上海农业学报,2013,29(4):128-131.]
[46] Dai JF,Yang Y,Fang RJ et al. Water quality analysis and segmentation of the pollution loads in different spatial scales of the upstream of Lijiang River. China Rural Water and Hydropower,2017,(4):67-71.[代俊峰,杨艺,方荣杰等.漓江流域上游水质分析和污染物定量分割.中国农村水利水电,2017,(4):67-71.]
[47] Golam R,Salma A,Partho PB et al. Effects of antibiotic treated fish diet on fish muscle,bacterial flora and water quality parameters under pond experimental condition. World Journal of Fish and Marine Sciences,2015,7(2):135-140. DOI:10.5829/idosi.wjfms.2015.7.2.93141.
[48] Fu H,Li XB,Wang J et al. Impacts of p H on adsorption of quinolones by PAC. China Water&Wastewater,2017,33(17):64-67.[付浩,李雪冰,汪隽等. p H值对活性炭吸附喹诺酮类抗生素影响的研究.中国给水排水,2017,33(17):64-67.]
[49] Huang SL,Zang CJ,Du SL et al. Study on the relationships among p H,dissolved oxygen and chlorophyll aⅠ:Aquaculture water. Chinese Journal of Environmental Engineering,2011,5(6):1201-1208.[黄岁樑,臧常娟,杜胜蓝等. p H、溶解氧、叶绿素a之间研究Ⅰ:养殖水体.环境工程学报,2011,5(6):1201-1208.]
[50] Chen SR,Wu ZM,Yu WB et al. Formation,harmfulness,prevention,control and treatment of waters eutrophication. Environmental Science&Technology,1999,22(2):11-15.[陈水勇,吴振明,俞伟波等.水体富营养化的形成、危害和防治.环境科学与技术,1999,22(2):11-15.]
[51] Wen YH,He AY. Water Eutrophication and comprehensive governance advice in Qingshitan Reservoir area of the upper Lijiang River. Fisheries Science&Technology of Guangxi,2006,(3):20-25.[文衍红,何安尤.漓江上游青狮潭库区水体富营养化及其综合治理建议.广西水产科技,2006,(3):20-25.]
[2] Zhang QQ,Ying GG,Pan CG et al. Comprehensive evaluation of antibiotics emission and fate in the river basins of China:source analysis,multimedia modeling,and linkage to bacterial resistance. Environmental Science&Technology,2015,49(11):6772-6782.
[3] Zhao TH,Chen YH,Han W et al. The contamination characteristics and ecological risk assessment of typical antibiotics in the upper reaches of the Dongjiang River. Ecology and Environmental Sciences,2016,25(10):1707-1713.[赵腾辉,陈奕涵,韩巍等.东江上游典型抗生素污染特征及生态风险评价.生态环境学报,2016,25(10):1707-1713.]
[4] Backhaus T,Scholze M,Grimme LH. The single substance and mixture toxicity of quinolones to the bioluminescent bacterium Vibrio fischeri. Aquatic Toxicology,2000,49(1):49-61.
[5] Hirsch R,Ternes T,Haberer K et al. Occurrence of antibiotics in the aquatic environment. Science of the Total Environment,1999,225(1/2):109-118.
[6] Zhou QX,Luo Y,Wang ME. Environmental residues and ecotoxicity of antibiotics and their resistance gene pollution:A review. Asian Journal of Ecotoxicology,2007,2(3):243-251.[周启星,罗义,王美娥.抗生素的环境残留、生态毒性及抗性基因污染.生态毒理学报,2007,2(3):243-251.]
[7] Zhang RJ,Zhang G,Zheng Q et al. Concentrations and spatial distributions of selected quinolones antibiotics in Laizhou Bay and main rivers flowing into the bay. Marine Environmental Science,2012,31(1):53-57.[张瑞杰,张干,郑芊等.喹诺酮类抗生素在莱州湾及主要入海河流中的含量和分布特征.海洋环境科学,2012,31(1):53-57.]
[8] Li J,Zhang RJ,Wang RM et al. Distribution characteristics and ecological risk assessment of antibiotic pollution in Xiaoqing River watershed. Journal of Agro-Environment Science,2016,35(7):1384-1391. DOI:10.11654/jaes.2016.07.022.[李嘉,张瑞杰,王润梅等.小清河流域抗生素污染分布特征与生态风险评估.农业环境科学学报,2016,35(7):1384-1391.]
[9] Baquero F,Martínez JL,Cantón R. Antibiotics and antibiotic resistance in water environments. Current Opinion in Biotechnology,2008,19(3):260-265.
[10] Crane M,Watts C,Boucard T. Chronic aquatic environmental risks from exposure to human pharmaceuticals. Science of the Total Environment,2006,367(1):23-41.
[11] Li Y,Jiang TT,Jing LF et al. Characteristics of residual organic pesticides and antibiotics in reservoirs of Zhoushan Islands and potential risk evaluation. Water Resources Protection,2014,30(3):31-37.[李勇,蒋婷婷,景龙飞等.舟山岛水库有机农药和抗生素残留特征及潜在风险评估.水资源保护,2014,30(3):31-37.]
[12] Feng L,Cheng YR,Feng L et al. Distribution of typical antibiotics and ecological risk assessment in main waters of Three Gorges Reservoir Area. Research of Environmental Sciences,2017,30(7):1031-1040.[封丽,程艳茹,封雷等.三峡库区主要水域典型抗生素分布及生态风险评估.环境科学研究,2017,30(7):1031-1040.]
[13] Zhu TT,Song ZH,Duan BB et al. Research on pollution and health risk by antibiotics in source water of Shiyan Reservoir in Shenzhen. Journal of Environment and Health,2013,30(11):1003-1006.[朱婷婷,宋战锋,段标标等.深圳石岩水库抗生素污染特征与健康风险初步评价.环境与健康杂志,2013,30(11):1003-1006.]
[14] Lu C,Zhang J,Wang Z et al. Determination and risk assessment of chloramphenicols in Panjiakou Reservoir,Hebei Province. China Environmental Science,2016,36(6):1843-1849.[卢诚,张俊,王钊等.河北潘家口水库氯霉素类抗生素检测及风险评估.中国环境科学,2016,36(6):1843-1849.]
[15] Liu XH,Lu SY. Occurrence and ecological risk of typical antibiotics in surface water of the Datong Lake,China. China Environmental Science,2018,38(1):320-329.[刘晓晖,卢少勇.大通湖表层水体中抗生素赋存特征与风险.中国环境科学,2018,38(1):320-329.]
[16] Tang J,Zha XX,Wang CC et al. Analysis of status of antibiotic residues in Lake Chaohu∥China Association for Science and Technology ed. Lake Basin Ecological Construction and Sustainable Development-Proceedings of the Second ChinaLake Forum. Changsha:Hunan People’s Press,2012:289-297.[唐俊,查欣欣,王晨晨等.巢湖湖水中抗生素残留现状分析∥中国科学技术协会.湖泊流域生态建设与可持续发展-第二届中国湖泊论坛论文集.长沙:湖南人民出版社,2012:289-297.]
[17] Jiang L,Hu XL,Yin DQ et al. Occurrence,distribution and seasonal variation of antibiotics in the Huangpu River,Shanghai,China. Chemosphere,2011,82(6):822-828.
[18] Wu XY,Zou H,Zhu R et al. Occurrence,distribution and ecological risk of antibiotics in surface water of the Gonghu Bay,Taihu Lake. Environmental Science,2016,37(12):4596-4604. DOI:10.13227/j. hjkx.201603005.[武旭跃,邹华,朱荣等.太湖贡湖湾水域抗生素污染特征分析与生态风险评价.环境科学,2016,37(12):4596-4604.]
[19] Liang X,Chen B,Nie X et al. The distribution and partitioning of common antibiotics in water and sediment of the Pearl River Estuary,South China. Chemosphere,2013,92(11):1410-1416.
[20] Minh TB,Leung HW,Loi HI et al. Antibiotics in the Hong Kong metropolitan area:Ubiquitous distribution and fate in Victoria Harbour. Marine Pollution Bulletin,2009,58(7):1052-1062.
[21] Chen L,Qian JP,Zhang L et al. Investigation and evaluation of water quality of blue lion tam reservoir in Guilin city.Journal of Guangxi Agriculture,2013,40(5):160-164.[陈磊,钱建平,张力等.桂林市青狮潭水库水质现状调查与评价.广东农业科学,2013,40(5):160-164.]
[22] Zheng YL,Han PL,Dai JF et al. Change of inflow runoff into the Qingshitan Reservoir in Guilin City. Water Conservancy Science and Technology and Economy,2012,18(8):46-48.[郑玉林,韩培丽,代俊峰等.桂林市青狮潭水库入库径流变化分析.水利科技与经济,2012,18(8):46-48.]
[23] Liang YP,Chen GN,Zeng HH et al. Characteristics and risk assessment of organochlorine pesticide residues in surface sediments collected at the Qingshitan Reservoir. Toxicological&Environmental Chemistry,2016,98(5/6):658-668.
[24] Yan YN,Cheng YP,Kang P et al. Pollution characteristics and potential ecological risk assessment of heavy metals in sediments of Qingshitan Reservoir. Yangtze River,2017,48(10):24-29.[闫雅妮,程亚平,康平等.青狮潭水库底泥重金属污染特征及潜在生态风险.人民长江,2017,48(10):24-29.]
[25] Kalff J,Gu BH,Liu ZW et al eds. Limnology:Inland water ecosystems. Beijing:Higher Education Press,2011.[Kalff J,古滨河,刘正文等.湖沼学:内陆水生态系统.北京:高等教育出版社,2011.]
[26] Miu ZL,Zong FS,Jiang YP eds. Study on Hydrographic Karst and Tourism Resources in Guilin. Wuhan:China University of Geosciences Press,2004.[缪钟灵,宗凤书,蒋亚萍.桂林水文岩溶及旅游资源研究.武汉:中国地质大学出版社,2004.]
[27] Qi SS,Yang X. Study on Ecological restoration mode of reservoir eutrophication by fish cage culture-case study of Qingshitan Reservoir. Environmental Science and Management,2012,37(11):151-154.[齐姗姗,杨雄.水库网箱养鱼富营养化生态修复模式研究——以青狮潭水库为例.环境科学与管理,2012,37(11):151-154.]
[28] Yu SL ed. HPLC method and application. Beijing:Chemical Industry Press,2005.[于世林.高效液相色谱方法及应用.北京:化学工业出版社,2005.]
[29] Dang G. Fluoremetric methods for the determination of Quinolones and studies on the interaction of Quinolones with metalions and bovine serum albumin[Dissertation].Hohhot:Inner Mongolia University,2005.[代钢.喹诺酮类药物的荧光分析方法及其与金属离子生物大分子作用的研究[学位论文].呼和浩特:内蒙古大学,2005.]
[30] Ding HJ,Zhong JY,Wu YX et al. Characteristics and ecological risk assessment of antibiotics in five city lakes in Nanchang City,Lake Poyang Catchment. J Lake Sci,2017,29(4):848-858. DOI:10.18307/2017.0408.[丁惠君,钟家有,吴亦潇等.鄱阳湖流域南昌市城市湖泊水体抗生素污染特征及生态风险分析.湖泊科学,2017,29(4):848-858.]
[31] Fang LF. Pollution characteristics and ecological risk assessment of typical antibiotics in the upper Huangpu River[Dissertation]. Shanghai:Donghua University,2016.[方龙飞.黄浦江上游典型抗生素污染特征及生态风险评估[学位论文].上海:东华大学,2016.]
[32] Hokstad P,Steiro T. Overall strategy for risk evaluation and priority setting of risk regulations. Radioisotopes,1985,91(1):100-111.
[33] Guérit I,BocquenéG,James A et al. Environmental risk assessment:a critical approach of the European TGD in an in situ application. Ecotoxicology&Environmental Safety,2008,71(1):291-300.
[34] Zhu TT,Duan BB,Song ZF et al. Pollution characteristics and ecological risk assessment of antibiotics in Tiegang Reser-voir in Shenzhen. Ecology and Environmental Sciences,2014,23(7):1175-1180.[朱婷婷,段标标,宋战锋等.深圳铁岗水库水体中抗生素污染特征分析及生态风险评价.生态环境学报,2014,23(7):1175-1180.]
[35] Qin YW,Zhang L,Shi Y et al. Contamination characteristics and ecological risk assessment of typical antibiotics in surface water of the Daliao River,China. Research of Environmental Sciences,2015,28(3):361-368.[秦延文,张雷,时瑶等.大辽河表层水体典型抗生素污染特征与生态风险评价.环境科学研究,2015,28(3):361-368.]
[36] Zou S,Xu W,Zhang R et al. Occurrence and distribution of antibiotics in coastal water of the Bohai Bay,China:Impacts of river discharge and aquaculture activities. Environmental Pollution,2011,159(10):2913-2920.
[37] Luo Y,Xu L,Rysz M et al. Occurrence and transport of tetracycline,sulfonamide,quinolone,and macrolide antibiotics in the Haihe River Basin,China. Environmental Science&Technology,2011,45(5):1827-1833.
[38] Li W,Shi Y,Gao L et al. Occurrence of antibiotics in water,sediments,aquatic plants,and animals from Baiyangdian Lake in North China. Chemosphere,2012,89(11):1307-1315.
[39] Zhang R,Zhang G,Zheng Q et al. Occurrence and risks of antibiotics in the Laizhou Bay,China:impacts of river discharge. Ecotoxicology&Environmental Safety,2012,80(2):208-215.
[40] Hernando MD,Mezcua M,Fernández-Alba AR et al. Environmental risk assessment of pharmaceutical residues in wastewater effluents,surface waters and sediments. Talanta,2006,69(2):334-342.
[41] Ma Y,Li M,Wu M et al. Occurrences and regional distributions of 20 antibiotics in water bodies during groundwater recharge. Science of the Total Environment,2015,518/519:498-506.
[42] Chang X,Meyer MT,Liu X et al. Determination of antibiotics in sewage from hospitals,nursery and slaughter house,wastewater treatment plant and source water in Chongqing region of Three Gorge Reservoir in China. Environmental Pollution,2010,158(5):1444-1450.
[43] Brown KD,Kulis J,Thomson B et al. Occurrence of antibiotics in hospital,residential,and dairy effluent,municipal wastewater,and the Rio Grande in New Mexico. Science of the Total Environment,2006,366(2/3):772-783.
[44] Guo XY,Wang N,Xu J et al. Research progress on environmental exposure levels and environmental fate of veterinary antibiotics. Environmental Science&Technology,2014,37(9):76-89.[郭欣妍,王娜,许静等.兽药抗生素的环境暴露水平及其环境归趋研究进展.环境科学与技术,2014,37(9):76-89.]
[45] Li J,Liu SJ. Advances in researching into the transformation and effects of antibiotics in an organic fertilizer-soil-crop systems.Acta Agriculturae Shanghai,2013,29(4):128-131.[李洁,刘善江.抗生素在有机肥料-土壤-农作物系统中的转化及影响的研究进展.上海农业学报,2013,29(4):128-131.]
[46] Dai JF,Yang Y,Fang RJ et al. Water quality analysis and segmentation of the pollution loads in different spatial scales of the upstream of Lijiang River. China Rural Water and Hydropower,2017,(4):67-71.[代俊峰,杨艺,方荣杰等.漓江流域上游水质分析和污染物定量分割.中国农村水利水电,2017,(4):67-71.]
[47] Golam R,Salma A,Partho PB et al. Effects of antibiotic treated fish diet on fish muscle,bacterial flora and water quality parameters under pond experimental condition. World Journal of Fish and Marine Sciences,2015,7(2):135-140. DOI:10.5829/idosi.wjfms.2015.7.2.93141.
[48] Fu H,Li XB,Wang J et al. Impacts of p H on adsorption of quinolones by PAC. China Water&Wastewater,2017,33(17):64-67.[付浩,李雪冰,汪隽等. p H值对活性炭吸附喹诺酮类抗生素影响的研究.中国给水排水,2017,33(17):64-67.]
[49] Huang SL,Zang CJ,Du SL et al. Study on the relationships among p H,dissolved oxygen and chlorophyll aⅠ:Aquaculture water. Chinese Journal of Environmental Engineering,2011,5(6):1201-1208.[黄岁樑,臧常娟,杜胜蓝等. p H、溶解氧、叶绿素a之间研究Ⅰ:养殖水体.环境工程学报,2011,5(6):1201-1208.]
[50] Chen SR,Wu ZM,Yu WB et al. Formation,harmfulness,prevention,control and treatment of waters eutrophication. Environmental Science&Technology,1999,22(2):11-15.[陈水勇,吴振明,俞伟波等.水体富营养化的形成、危害和防治.环境科学与技术,1999,22(2):11-15.]
[51] Wen YH,He AY. Water Eutrophication and comprehensive governance advice in Qingshitan Reservoir area of the upper Lijiang River. Fisheries Science&Technology of Guangxi,2006,(3):20-25.[文衍红,何安尤.漓江上游青狮潭库区水体富营养化及其综合治理建议.广西水产科技,2006,(3):20-25.]
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