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通过前瞻性随机对照试验研究,证明靳三针治老年功能性便秘的有效性、安全性及可推广性,为临床寻找一种使用方便、疗效快捷、无毒副作用、适于推广应用的治疗便秘的方法。
方法:
诊断标准根据1997年卫生部发布的《中药新药临床研究指导原则》制定。采用随机对照方法,将60例患者随机分为2组,其中治疗组30例,采用靳三针治疗;对照组30例,采用常规体针治疗。治疗三个疗程后,对比治疗前后的疗效、症状改善及SAS焦虑症状自评量表。
结果:
1、总有效率:治疗组为87.5%,对照组为80.00%。治疗组治疗前后组内比较p＜0.05,对照组治疗前后组内比较p＜0.05,说明两组疗效对治疗老年性便秘均有明显疗效。两组治疗后组间比较没有统计学意义(p＞0.05),说明两组疗效没有统计学差异。
2、Bristol粪便性状正常率:治疗前治疗组为28.1%,对照组为20.0%;治疗后治疗组为75.0%,对照组为60.0%。治疗组治疗前后组内比较有显著性的差异(p＜0.01);对照组治疗前后组内比较有显著性的差异(p＜0.01)。两组治疗后组间比较有统计学意义(p＜0.05)。
3、临床症状积分:①治疗后治疗组总积分为7.8±2.58,对照组为9.2±2.86。两组各自治疗前后组内比较,均有明显统计学差异(p＜0.01);两组治疗后积分组间比较没有统计学意义(p＞0.05)。②治疗后临床主症积分两组组间比较没有显著性差异(p＜0.05)。③治疗后临床兼症积分两组组间比较具有显著性的差异(p＜0.05)。
4、SAS标准分:治疗后治疗组SAS标准分为38.1±6.5,对照组为51.2±8.9,两组治疗后组间比较具有统计学差异(p＜0.05)。
结论:
通过对老年性便秘患者的临床疗效观察,认为靳三针在治疗老年性便秘方面具有肯定的疗效。研究结果表明此疗法能改善临床主症之余,还能有效地改善其伴随症状及焦虑情绪。
Objective:
To observe the clinical effect of Jin' s Three-Needle therapy in the treatment of functional constipation in senile patients.
Method:
Using the diagnostic criteria outlined by "The Clinical Guide to Research in New Chinese Drugs" in 1997,a total of sixty patients were randomly divided into treatment and control groups.Patients in the treatment group were treated with Jin' s Three-Needle therapy,while those in the control group were treated according to the routine acupuncture method.After 3 courses of treatment,data including the form of feces,relevant symptoms and the level of anxiety in the patients were assessed and statistically analyzed.
Results:
1.Total effective rate:The total effective rate of the treatment group was 87.5%,and that of the control group was 80.00%.Both groups were significantly effective in treating senile functional constipation. In both groups,there was a significant change in their before and after effect(p<0.05,respectively).However,the effective rates between the groups were not significantly different(p>0.05),indicating that the effectiveness of the two therapies were similar.
2.Stool Normality Rate:Before treatment,the rate of the treatment group was 28.1%and that of the control group was 20.0%;after treatment, the treatment group' s rate increased to 75.0%and the control group to 60.0%.Clearly shown and through statistical analysis,their before and after effect in both groups was significant(p<0.01).Moreover,the rates after treatment when compared between the two groups also showed significance(p<0.05),indicating that the treatment group was more effective in improving the form of stool in the senile constipated patients.
3.Symptom Index Score:①The score after treatment was 7.8±2.58 for the treatment group,and that for the control group was 9.2±2.86. The change in the before and after scores for both groups were significant(p<0.01).The after treatment scores between the groups were not significantly different(p>0.05).②The scores achieved for the primary symptoms were not significantly different when compared between the groups(p>0.05).③The scores for the secondary symptoms were significantly different between the groups(p>0.05).
4.SAS Standard Scores for Anxiety:After treatment,the score of the treatment group was 38.1±6.5,and that of the control group was 51.2±8.9.The change in the scores after treatment between the groups was significantly different(p<0.05),indicating that the treatment group was more effective in relieving the level of anxiety in the senile constipated patients.
Conclusions:
Jin' s Three-Needle Therapy had a significant clinical effect in the treatment of senile constipation.As proven in the study,the therapy is effective in not only relieving the primary symptoms of constipation,but also improving the secondary symptoms and easing the anxiety experienced in the patients.
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