中药复方治疗气虚血瘀型冠心病心绞痛的研究进展
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摘要
整理了近年来的常用传统中药复方、现代复方制剂治疗气虚血瘀型冠心病心绞痛的概况。结果显示:治疗气虚血瘀型冠心病心绞痛的总的治则为益气活血化瘀;治疗气虚血瘀型冠心病心绞痛的传统中药复方有补气活血化瘀、健脾益气活血、温阳益气活血类方,代表方分别为补阳还五汤、保元汤、参芪四物汤、血府逐瘀汤,四君子汤、归脾汤,四逆汤、益气温阳通痹汤;治疗气虚血瘀型冠心病心绞痛的现代复方制剂主要有养心氏片、稳心颗粒、参松养心胶囊、芪参胶囊、芪苈强心胶囊、通心络胶囊、参附注射液等。
The general overview of Chinese medicine compound formulas in treating coronary cardiopathy inducedangina with Qi-deficiency and blood-stasis type was reviewed. The results showed that the therapeutic principle forcoronary cardiopathy induced angina with Qi-deficiency and blood-stasis type is tonifying Qi,activating blood andresolving stasis; the Chinese medicine compound formulas for coronary cardiopathy induced angina with Qi-deficiency and blood-stasis type can be classified into recipes for tonifying Qi,activating blood and resolving stasis(corresponding representative recipes being Buyang Huanwu Decoction, Baoyuan Decoction, Shenqi Siwu Decoction, Xuefu Zhuyu Decoction), recipes for strengthening spleen, tonifying Qi and activating blood(corresponding representative recipes being Sijunzi Decoction and Guipi Decoction), and recipes for warmingyang, tonifying Qi and activating blood(corresponding representative recipes being Sini Decoction and Yiqi Wenyang Tongbi Decoction);the modern Chinese medicine patents for coronary cardiopathy induced angina withQi-deficiency and blood-stasis type are Yangxinshi Tablets, Wenxin Granules, Shensong Yangxin Capsules,Qishen Capsules,Qili Qiangxin Capsules,Tongxinluo Capusles,Shenfu Injection,etc.
The general overview of Chinese medicine compound formulas in treating coronary cardiopathy inducedangina with Qi-deficiency and blood-stasis type was reviewed. The results showed that the therapeutic principle forcoronary cardiopathy induced angina with Qi-deficiency and blood-stasis type is tonifying Qi,activating blood andresolving stasis; the Chinese medicine compound formulas for coronary cardiopathy induced angina with Qi-deficiency and blood-stasis type can be classified into recipes for tonifying Qi,activating blood and resolving stasis(corresponding representative recipes being Buyang Huanwu Decoction, Baoyuan Decoction, Shenqi Siwu Decoction, Xuefu Zhuyu Decoction), recipes for strengthening spleen, tonifying Qi and activating blood(corresponding representative recipes being Sijunzi Decoction and Guipi Decoction), and recipes for warmingyang, tonifying Qi and activating blood(corresponding representative recipes being Sini Decoction and Yiqi Wenyang Tongbi Decoction);the modern Chinese medicine patents for coronary cardiopathy induced angina withQi-deficiency and blood-stasis type are Yangxinshi Tablets, Wenxin Granules, Shensong Yangxin Capsules,Qishen Capsules,Qili Qiangxin Capsules,Tongxinluo Capusles,Shenfu Injection,etc.
引文
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[15]张建昌,曾远.益气温阳通痹汤治疗劳力性心绞痛临床疗效观察[J].中西医结合心脑血管病杂志,2017,15(6):699.
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[17]林欣.养心氏治疗气虚血瘀型冠心病的临床疗效观察[J].世界中医药,2017,12(1):100.
[18]张聪,欧阳竞锋,洪毅,等.养心氏片对气虚血瘀证慢性心肌缺血模型大鼠缺血损伤的保护作用[J].中西医结合心脑血管病杂志,2016,14(18):2107.
[19]向家培,王贤恩,张复贵.稳心颗粒对于心肌缺血性疾病大鼠模型的影响[J].中西医结合心脑血管病杂志,2015,13(15):1728.
[20]姚辉臣.参松养心胶囊治疗稳定型心绞痛疗效及对hs-CRP及IL-6的影响[J].广东医学,2017,38(增刊):268.
[21]李瑞梅.芪参胶囊治疗稳定型心绞痛临床观察[J].中国中医急症,2016,25(2):318.
[22]牛平平,陈小光,李松.芪苈强心胶囊治疗气虚血瘀型冠心病心绞痛的临床疗效及机制[J].现代生物医学进展,2018,14(18):2701.
[23]段丙军,林德智,熊富权,等.通心络胶囊治疗气虚血瘀型冠心病心绞痛的疗效及作用机制[J].疑难病杂志,2016,15(10):1065.
[24]苏庆侦.参附注射液治疗气虚血瘀型胸痹心痛临床研究[J].中国处方药,2018,16(3):110.
[25]吴春燕.冠心病的中医治疗用药规律分析[J].中西医结合心血管病电子杂志,2018,16(10):159.
[2] Petite S E,Bishop B M,Mauro V F. Role of the funny current inhibitor ivabradine in cardiac pharmacotherapy:a systematic review[J]. Am J Ther,2018,25(2):247.
[3]戴丽华.补阳还五汤加减治疗冠心病心绞痛40例效果观察[J].中西医结合心血管病电子杂志,2018,16(6):150.
[4]汪强,谷惠敏,朱建中,等.补阳还五汤治疗气虚血瘀型冠心病心绞痛的临床回顾性研究[J].南京中医药大学学报,2017,33(6):579.
[5]骆玉玲,黄玉萍,黄水霞,等.益气活血豁痰通络法治疗不稳定型心绞痛的临床观察[J].云南中医中药杂志,2017,38(11):38.
[6]张志刚,边文贵.保元汤合血府逐瘀汤治疗气虚血瘀型冠心病临床观察[J].中西医结合心血管病电子杂志,2015,13(5):94.
[7]许涛.保元汤合丹参饮治疗气虚血瘀型冠心病临床疗效观察[J].光明中医,2013,28(6):1190.
[8]邓怀玉.参芪四物汤治疗冠心病稳定性心绞痛32例疗效观察[J].中医临床研究,2017,9(4):83.
[9]张丽霞.参芪四物汤治疗冠心病的疗效观察[J].中西医结合心血管病电子杂志,2017,15(26):117.
[10]仇军,顾晶.血府逐瘀汤加减治疗气虚血瘀型不稳定性心绞痛100例[J].环球中医药,2016,9(11):1386.
[11]张松峰,郑直,石洪,等.从脾论治气虚血瘀证不稳定型心绞痛的临床研究[J].世界中医药,2017,12(9):2014.
[12]周兆玲,高晓玲,陈梦雅,等.归脾汤加减治疗气虚血瘀型冠心病心绞痛90例疗效观察[J].甘肃科技, 2015, 31(23):107.
[13]魏建梁,陈兴娟,杨传华.张文高教授益气温阳活血方治疗冠心病心绞痛述要[J].中华中医药杂志,2015,30(2):443.
[14]贾壮壮,王志刚.温肾法治疗心肾阳虚型冠心病心绞痛43例疗效观察[J].湖南中医杂志,2017,33(9):56.
[15]张建昌,曾远.益气温阳通痹汤治疗劳力性心绞痛临床疗效观察[J].中西医结合心脑血管病杂志,2017,15(6):699.
[16]何浩强,高嘉良,陈光,等.治疗气虚血瘀证中成药的组方规律分析[J].中国药房,2017,28(35):4910.
[17]林欣.养心氏治疗气虚血瘀型冠心病的临床疗效观察[J].世界中医药,2017,12(1):100.
[18]张聪,欧阳竞锋,洪毅,等.养心氏片对气虚血瘀证慢性心肌缺血模型大鼠缺血损伤的保护作用[J].中西医结合心脑血管病杂志,2016,14(18):2107.
[19]向家培,王贤恩,张复贵.稳心颗粒对于心肌缺血性疾病大鼠模型的影响[J].中西医结合心脑血管病杂志,2015,13(15):1728.
[20]姚辉臣.参松养心胶囊治疗稳定型心绞痛疗效及对hs-CRP及IL-6的影响[J].广东医学,2017,38(增刊):268.
[21]李瑞梅.芪参胶囊治疗稳定型心绞痛临床观察[J].中国中医急症,2016,25(2):318.
[22]牛平平,陈小光,李松.芪苈强心胶囊治疗气虚血瘀型冠心病心绞痛的临床疗效及机制[J].现代生物医学进展,2018,14(18):2701.
[23]段丙军,林德智,熊富权,等.通心络胶囊治疗气虚血瘀型冠心病心绞痛的疗效及作用机制[J].疑难病杂志,2016,15(10):1065.
[24]苏庆侦.参附注射液治疗气虚血瘀型胸痹心痛临床研究[J].中国处方药,2018,16(3):110.
[25]吴春燕.冠心病的中医治疗用药规律分析[J].中西医结合心血管病电子杂志,2018,16(10):159.
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