摘要
2016年澳大利亚胃肠病学会等多家机构组织专家联合撰写并发布了《2016年澳大利亚丙型肝炎病毒(HCV)感染诊治指南》,内容涉及澳大利亚HCV感染的流行现状及管理模式、HCV感染的筛查及诊断、治疗前评估、治疗方案选择、治疗期间监测及治疗后随访等。本研究对其中特殊人群的抗HCV治疗、抗病毒药物安全性及相互作用进行解读,并着重与《2015年中国丙型肝炎防治指南》《2016年欧洲肝病学会丙型肝炎治疗指南》《2015年加拿大肝病学会慢性丙型肝炎管理共识指南》《2015及2016年美国肝病学会丙型肝炎治疗指南》《2016年英国HCV感染诊治指南》以及《2016年世界卫生组织丙型肝炎治疗指南》中的相应内容进行比较,以期为临床肝病医生了解各个指南推荐意见的异同、规范HCV感染的临床诊治提供便利。
In 2016, experts from the Gastroenterology Society of Australia and other organizations jointly wrote and published "the Guidelines for the Diagnosis and Treatment of Hepatitis C Virus(HCV) Infection in Australia in 2016", which covered the epidemic situation and management mode of HCV infection in Australia, the screening and diagnosis of HCV infection, pre-treatment evaluation, treatment options, monitoring during treatment and follow-up after treatment, etc. This study interpreted anti-HCV therapy in special population, safety and interaction of antiviral agents, focusing on a comparison between "Guidelines for the Prevention and Treatment of Hepatitis C in China in 2015", "Guidelines for the Treatment of Hepatitis C by Hepa-tology Society of European in 2016", "Guidelines for the Consensus on the Management of Chronic Hepatitis C by the Hepatology Society of Canada in 2015", "Guidelines for the Treatment of Hepatitis C by the Hepatology Society of America in 2015 and 2016","Guidelines for the Diagnosis and Treatment of Hepatitis C in England in 2016"and"the Guidelines for the Treatment of Hepatitis C by the World Health Organization in2016". This article aimed at comparing the recently released Australian consensus for the management of HCV infection with the guidelines of China and several other countries/organizations in order to bring readers to important considerations in the management of HCV patients.
引文
[1]刘姝,王炳元,乔梁.2016年澳大利亚丙型肝炎病毒感染诊治指南及各国指南之对比解读--Ⅰ.筛查、诊断及治疗前评估[J].兰州大学学报:医学版,2016,42(6)73-77
[2]刘姝,王炳元,乔梁,等.2016年澳大利亚丙型肝炎病毒感染诊治指南及各国指南之对比解读--Ⅱ.丙型肝炎病毒的规范化抗病毒治疗[J].兰州大学学报:医学版,2018,44(6):62-69
[3]澳大利亚胃肠病学会,澳大利亚肝脏协会,澳亚传染病学会,等.2016年澳大利亚丙型肝炎病毒感染诊治专家共识推荐[Z].2016
[4]AASLD.HCV guidance:recommendations for testing,managing,and treating hepatitis C[Z].2016
[5]AASLD/IDSA.Hepatitis C guidance:AASLD-IDSArecommendations for testing,managing,and treating adults infected with hepatitis C virus[J].Hepatology,2015,62(3):932-954
[6]Falade-Nwulia O,Sutcliffe C,Moon J,et al.High Hepatitis C cure rates among black and nonblack human immunodeficiency virus-infected adults in an urban center[J].Hepatology,2017,66(5):1402-1412
[7]Liu CJ,Chuang WL,Sheen IS,et al.Efficacy of ledipasvir and sofosbuvir treatment of HCV infection in patients coinfected with HBV[J].Gastroenterology,2018,154(4):989-997
[8]赵西太,聂青和.直接抗病毒药物治疗丙型肝炎的毒副作用、药物相互作用及安全性[J].临床肝胆病杂志,2017,33(6):1067-1074