脑梗通汤辨证治疗气虚血瘀型脑梗死恢复期偏瘫的临床疗效
|
摘要
目的:研究脑梗通汤辨证治疗气虚血瘀型脑梗死恢复期偏瘫的临床效果。方法:选择2015年7月—2017年3月在本院进行康复治疗的100例脑梗死恢复期气虚血瘀型偏瘫患者,采用随机数字表法随机均分为两组。对照组采用舒血宁注射液治疗;观察组在此基础上配合脑梗通汤进行治疗。观察记录两组治疗效果,采用简式Fugl-Meyer评定量表和日常生活活动能力Barthel指数评定表评价患侧肢体运动功能和日常生活能力,并检测比较两组患者治疗前后血液流变学指标变化情况。结果:观察组患者临床总有效率98.00%明显高于对照组80.00%,差异有统计学意义(P<0.05)。治疗后,两组患者FMA评分、ADL评分明显上升;且观察组FMA和ADL评分明显高于对照组(P<0.05)。两组患者治疗后,血液流变学指标均明显改善;观察组全血黏度、血浆纤维蛋白原、红细胞聚集指数及血浆黏度均明显低于对照组,血液流变学改善程度明显优于对照组(P<0.05)。结论:脑梗通汤辨证治疗气虚血瘀型脑梗死恢复期偏瘫患者,能有效改善其偏瘫肢体功能和日常生活能力,改善患者血液流变学,提高患者生存质量。
Objective:To study the clinical effect of Naogengtong Decoction for treating Qi deficiency and blood stasis type of cerebral infarction hemiplegia.Methods:From July 2015 to March 2017,100 patients with hemiplegia at the convalescent stage of cerebral infarction in our hospital were randomly divided into two groups.The control group was treated by Shuxuening Injection.On the basis, the observation group was treated with Naogengtong Decoction.We observed and recorded the treatment effect of the two groups by the simple Fugl-Meyer scale and Barthel ADL index evaluation of limb motor function and ability of daily living and detected two groups′ blood rheology indexes before and after treatment.Results:The total effective rate of the observation group was 98%,which was higher than that of the control group(80%).The difference was statistically significant(P<0.05).After treatment,the FMA and ADL scores of the two groups increased significantly and the scores of FMA and ADL in the observation group were significantly higher than those in the control group(P<0.05).Two groups′ blood rheology indexes were significantly improved after treatment.The observation group′s blood viscosity,plasma fibrinogen,erythrocyte aggregation index and plasma viscosity were significantly lower than those of the control group.The blood rheology improved significantly better than that of the control group(P<0.05).Conclusion:Naogengtong Decoction combined with Shuxuening Injection in the treatment of cerebral infarction of Qi deficiency and blood stasis in patients with hemiplegia can effectively improve the hemiplegic limb function and daily life ability,blood rheology and the quality of life of patients.
Objective:To study the clinical effect of Naogengtong Decoction for treating Qi deficiency and blood stasis type of cerebral infarction hemiplegia.Methods:From July 2015 to March 2017,100 patients with hemiplegia at the convalescent stage of cerebral infarction in our hospital were randomly divided into two groups.The control group was treated by Shuxuening Injection.On the basis, the observation group was treated with Naogengtong Decoction.We observed and recorded the treatment effect of the two groups by the simple Fugl-Meyer scale and Barthel ADL index evaluation of limb motor function and ability of daily living and detected two groups′ blood rheology indexes before and after treatment.Results:The total effective rate of the observation group was 98%,which was higher than that of the control group(80%).The difference was statistically significant(P<0.05).After treatment,the FMA and ADL scores of the two groups increased significantly and the scores of FMA and ADL in the observation group were significantly higher than those in the control group(P<0.05).Two groups′ blood rheology indexes were significantly improved after treatment.The observation group′s blood viscosity,plasma fibrinogen,erythrocyte aggregation index and plasma viscosity were significantly lower than those of the control group.The blood rheology improved significantly better than that of the control group(P<0.05).Conclusion:Naogengtong Decoction combined with Shuxuening Injection in the treatment of cerebral infarction of Qi deficiency and blood stasis in patients with hemiplegia can effectively improve the hemiplegic limb function and daily life ability,blood rheology and the quality of life of patients.
引文
[1] 姜迎萍,王波,周益凡,等.头针结合康复训练治疗脑梗死恢复期患者的疗效研究[J].中国康复医学杂志,2017,32(3):288-292.
[2] 姚广明,刘朋飞,李鹏亮,等.补阳还五汤对脑缺血治疗作用机制[J].中国老年学杂志,2016,36(6):1533-1535.
[3] Pramod Kumar,Rekha Paulose.Patch Testing in Suspected Allergic Contact Dermatitis to Cosmetics[J].Dermatol Res Pract,2014,2014:695387.PMCID:PMC4175377
[4] 全国第四次脑血管病学术会议.各类脑血管疾病诊断要点[J].中华神经科杂志,1997,29(6):379.
[5] 丁玉梅,马晓勇.补阳还五汤加味治疗下肢慢性静脉功能不全临床观察[J].河北中医,2016,38(3):419-421.
[6] 董雯,李保玉,屈园利,等.补阳还五汤治疗脑梗死恢复期气虚血瘀证的Meta分析[J].中西医结合心脑血管病杂志,2016,14(6):580-585.
[7] 罗银河,葛金文,刘林,等.补阳还五汤治疗缺血性中风临床应用进展[J].中西医结合心脑血管病杂志,2016,14(3):278-281.
[8] Bansari Patel,Sonia Elguero,Suruchi Thakore.Role of nuclear progesterone receptor isoforms in uterine pathophysiology[J].Hum Reprod Update,2015,21(2):155-173 .PMCID:PMC 4366574
[9] 李积军.丹红注射液联合依达拉奉治疗急性脑梗死的疗效观察[J].中国中西医结合急救杂志,2015,17(2):178-180.
[10] Caroline H Diep,Andrea R Daniel,Laura J.Progesterone action in breast,uterine,and ovarian cancers[J].J Mol Endocrinol,2015,54(2):R31-R53.PMCID:PMC 4336822
[11] 李晓红,范朝阳.益气通络中药熏蒸治疗脑梗塞恢复期30例[J].陕西中医,2014,11(5):552-553.
[12] 乔树斌.脉血康胶囊治疗脑梗塞恢复期40例[J].陕西中医,2015,22(3):278-279.
[13] 赵乾龙.加味补阳还五汤治疗脑梗塞恢复期临床观察[J].中医临床研究,2014,6(35):66-67
[14] 郭静姬.针灸结合通痹益脑汤治疗脑梗死后血管性痴呆的临床效果[J].临床医学,2017,37(1):114-115.
[15] 黄庆松,王朝,马玉苹,等.红花黄色素配合西药治疗脑梗塞及对血液流变学的影响[J].陕西中医,2014,9(12):1610-1612.
[16] 王伟芳,彭涛.通脑汤联合西药治疗脑梗死后血管性痴呆效果观察[J].河南医学研究,2016,25(11):1970-1971.
[17] 李丽娜.涤痰汤合通窍活血汤联合吞咽功能训练对脑梗死后吞咽障碍的疗效观察[J].陕西中医,2016,37(5):526-528.
[18] 王婷,闫咏梅,曹影,等.丹红注射液治疗中风(恢复期)瘀血闭阻证的临床研究[J].中西医结合心脑血管病杂志,2014,12(2):148-151.
[19] 王妍,许能贵,曹月红,等.丹红注射液联合依达拉奉治疗急性脑梗死有效性及安全性系统评价[J].医药导报,2016,35(7):780-788.
[20] 熊维,常飞.脑心通胶囊联合丹红注射液治疗急性脑梗死的临床疗效及其机制探讨[J].华中科技大学学报(医学版),2016,45(1):74-77.
[2] 姚广明,刘朋飞,李鹏亮,等.补阳还五汤对脑缺血治疗作用机制[J].中国老年学杂志,2016,36(6):1533-1535.
[3] Pramod Kumar,Rekha Paulose.Patch Testing in Suspected Allergic Contact Dermatitis to Cosmetics[J].Dermatol Res Pract,2014,2014:695387.PMCID:PMC4175377
[4] 全国第四次脑血管病学术会议.各类脑血管疾病诊断要点[J].中华神经科杂志,1997,29(6):379.
[5] 丁玉梅,马晓勇.补阳还五汤加味治疗下肢慢性静脉功能不全临床观察[J].河北中医,2016,38(3):419-421.
[6] 董雯,李保玉,屈园利,等.补阳还五汤治疗脑梗死恢复期气虚血瘀证的Meta分析[J].中西医结合心脑血管病杂志,2016,14(6):580-585.
[7] 罗银河,葛金文,刘林,等.补阳还五汤治疗缺血性中风临床应用进展[J].中西医结合心脑血管病杂志,2016,14(3):278-281.
[8] Bansari Patel,Sonia Elguero,Suruchi Thakore.Role of nuclear progesterone receptor isoforms in uterine pathophysiology[J].Hum Reprod Update,2015,21(2):155-173 .PMCID:PMC 4366574
[9] 李积军.丹红注射液联合依达拉奉治疗急性脑梗死的疗效观察[J].中国中西医结合急救杂志,2015,17(2):178-180.
[10] Caroline H Diep,Andrea R Daniel,Laura J.Progesterone action in breast,uterine,and ovarian cancers[J].J Mol Endocrinol,2015,54(2):R31-R53.PMCID:PMC 4336822
[11] 李晓红,范朝阳.益气通络中药熏蒸治疗脑梗塞恢复期30例[J].陕西中医,2014,11(5):552-553.
[12] 乔树斌.脉血康胶囊治疗脑梗塞恢复期40例[J].陕西中医,2015,22(3):278-279.
[13] 赵乾龙.加味补阳还五汤治疗脑梗塞恢复期临床观察[J].中医临床研究,2014,6(35):66-67
[14] 郭静姬.针灸结合通痹益脑汤治疗脑梗死后血管性痴呆的临床效果[J].临床医学,2017,37(1):114-115.
[15] 黄庆松,王朝,马玉苹,等.红花黄色素配合西药治疗脑梗塞及对血液流变学的影响[J].陕西中医,2014,9(12):1610-1612.
[16] 王伟芳,彭涛.通脑汤联合西药治疗脑梗死后血管性痴呆效果观察[J].河南医学研究,2016,25(11):1970-1971.
[17] 李丽娜.涤痰汤合通窍活血汤联合吞咽功能训练对脑梗死后吞咽障碍的疗效观察[J].陕西中医,2016,37(5):526-528.
[18] 王婷,闫咏梅,曹影,等.丹红注射液治疗中风(恢复期)瘀血闭阻证的临床研究[J].中西医结合心脑血管病杂志,2014,12(2):148-151.
[19] 王妍,许能贵,曹月红,等.丹红注射液联合依达拉奉治疗急性脑梗死有效性及安全性系统评价[J].医药导报,2016,35(7):780-788.
[20] 熊维,常飞.脑心通胶囊联合丹红注射液治疗急性脑梗死的临床疗效及其机制探讨[J].华中科技大学学报(医学版),2016,45(1):74-77.
© 2004-2018 中国地质图书馆版权所有 京ICP备05064691号 京公网安备11010802017129号 地址：北京市海淀区学院路29号 邮编：100083 电话：办公室：(+86 10)66554848；文献借阅、咨询服务、科技查新：66554700 |