咸宁产青砖茶对营养性肥胖小鼠体质量和血脂的影响
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摘要
目的研究观察不同浓度咸宁产青砖茶对高脂饮食诱导的营养性肥胖小鼠体质量和血脂的影响。方法用高脂饲料诱导昆明小鼠肥胖后,每日给予经旋转蒸发浓缩的高(33. 6g/90mL)、中(16. 8g/90mL)、低(8. 4g/90mL)浓度青砖茶水0. 3mL灌胃,并分别给予不同浓度的青砖茶水(9. 6g/L,4. 8g/L,2. 4g/L)自由饮用,喂养36d。实验期间记录摄食量、体质量、体长。实验结束后,摘眼球取血,全自动生化仪测血清TC、TG、HDL、LDL含量,并解剖称取小鼠肾周及睾周脂肪垫质量。结果与模型组比较,青砖茶水对肥胖小鼠体质量、脂肪系数均具有显著的抑制作用,且呈剂量依赖性;但对血脂四项均无明显影响。结论青砖茶水对肥胖小鼠有显著的减肥作用,无明显调节血脂作用。
Objective To explore the effect of Qingzhuan brick tea from Xianning on weight gain and blood fat of diet-induced obese mice. Methods Qingzhuan brick tea aqueous extracts concentrated by rotary evaporation were poured into obese rats' stomach through mouth once a day for 36 consecutive days with 0. 3 ml at different concentration levels: 33. 6 g/90 mL,16. 8 g/90 mL and 8. 4 g/90 mL. Meanwhile,tea samples of three dose levels( 9. 6 g/L,4. 8 g/L,and 2. 4 g/L) were repectively given to above-mentioned three groups of rats to drink freely. Dietary intake,body weight and body length were recorded during the experiment. When the experiment was over,all experimental rats were took blood by removalling eyeballs,and then full-automatic bio-chemical instrument was used to measure TC,TG,HDL,and LDL. In addition,both perirenal fat and epidodymal fat were also weighed. Results Compared to the model group,Qingzhuan brick tea has a significant dose-dependent inhibitory effect against weight gain and coefficient of fat. However,no significant effect was found on blood fat in this study.Conclusion Qingzhuan brick tea has an anti-obesity effect,but it has no effect in regulating blood lipid.
Objective To explore the effect of Qingzhuan brick tea from Xianning on weight gain and blood fat of diet-induced obese mice. Methods Qingzhuan brick tea aqueous extracts concentrated by rotary evaporation were poured into obese rats' stomach through mouth once a day for 36 consecutive days with 0. 3 ml at different concentration levels: 33. 6 g/90 mL,16. 8 g/90 mL and 8. 4 g/90 mL. Meanwhile,tea samples of three dose levels( 9. 6 g/L,4. 8 g/L,and 2. 4 g/L) were repectively given to above-mentioned three groups of rats to drink freely. Dietary intake,body weight and body length were recorded during the experiment. When the experiment was over,all experimental rats were took blood by removalling eyeballs,and then full-automatic bio-chemical instrument was used to measure TC,TG,HDL,and LDL. In addition,both perirenal fat and epidodymal fat were also weighed. Results Compared to the model group,Qingzhuan brick tea has a significant dose-dependent inhibitory effect against weight gain and coefficient of fat. However,no significant effect was found on blood fat in this study.Conclusion Qingzhuan brick tea has an anti-obesity effect,but it has no effect in regulating blood lipid.
引文
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[2]王茹茹,肖孟超,李大祥,等.黑茶品质特征及其健康功效研究进展[J].茶叶科学,2018,38(2):113
[3]卢素芳,郑鹏程,刘盼盼,等.青砖茶研究进展[J].茶叶学报,2018,59(3):162
[4]方学军.砖茶中氟的饮用安全性研究现状[J].湖南林业科技,2011,38(2):85
[5]黄文河,黎瑞庭,黄凤莲,等.黑茶对于调节代谢综合征的作用研究[J].首都食品与医药,2016,23(12):29
[6]黄继汉,黄晓晖,陈志扬,等.药理试验中动物间和动物与人体间的等效剂量换算[J].中国临床药理学与治疗学,2004,9(9):1069
[7]许姗姗,宁井铭,姜浩,等.青砖茶品质与保健功效的研究进展[J].茶业通报,2017,39(3):108
[8]付婷,韩国柱.茶多酚的药动学研究进展[J].中草药,2010,41(12):2102
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