奶牛养殖中霉菌毒素的危害及其防控方法研究进展
|
摘要
近年来,霉菌毒素污染饲料已经引起饲料行业的高度重视。奶牛采食被霉菌毒素污染的饲料后很容易引发各种疾病,有些霉菌毒素还会代谢进入牛奶中对人们的健康造成威胁。本文主要就霉菌毒素对奶牛的危害及其防控方法的研究进行综述,以期为生产实践中降低霉菌毒素的危害提供理论参考。
In recent years, the problem of mycotoxin contaminating feed has aroused the attention of the feed industry. It is easy for cows to cause various diseases after eating feed contaminated with mycotoxins, and some mycotoxins are also metabolized into milk, which threatens the health of people. In this paper, the harm of mycotoxin to dairy cows and their prevention and control methods are reviewed, so as to provide some theoretical references for reducing the harm of mycotoxin in production practice.
In recent years, the problem of mycotoxin contaminating feed has aroused the attention of the feed industry. It is easy for cows to cause various diseases after eating feed contaminated with mycotoxins, and some mycotoxins are also metabolized into milk, which threatens the health of people. In this paper, the harm of mycotoxin to dairy cows and their prevention and control methods are reviewed, so as to provide some theoretical references for reducing the harm of mycotoxin in production practice.
引文
[1]Hussein H S,Brasel J M.Toxicity,metabolism,and impact of mycotoxins on humans and animals[J].Toxicology,2001,167(2):101-134.
[2]冯艳忠,沈伟,王兆山,等.霉菌毒素的研究进展[J].饲料工业,2014,35(4):58-62.
[3]陈波.霉菌毒素对奶牛的危害及防治[J].中国乳业,2013(10):26-28.
[4]Iheshiulor O O M,Esonu B O,Chuwuka O K,et al.Effects of mycotoxins in animal nutrition:A review[J].Asian-Austra JAnim Sci,2011,5(1):19-33.
[5]刘凤芝,李锋,王永丽.2017年上半年我国部分地区饲料及饲料原料中霉菌毒素的污染状况分析[J].粮食与饲料工业,2017(11):46-50.
[6]李孟孟,翟双双,王文策,等.饲料中霉菌毒素的危害及其降解方法研究进展[J].中国家禽,2016,38(5):37-41.
[7]欧阳富龙,彭媛媛,张光磊,等.饲料原料中常见霉菌毒素的危害及处理[J].中国畜牧业,2017(1):60-62.
[8]孙永明.饲料中常见霉菌毒素及产生原因[J].上海畜牧兽医通讯,2012(3):86.
[9]Ding X,Li P,Bai Y,et al.Aflatoxin B 1,in post-harvest peanuts and dietary risk in China[J].Food Control,2012,23(1):143-148.
[10]Keller L A M,Pereyra M L G,Keller K M,et al.Fungal and myc-otoxins contamination in corn silage:Monitoring risk before and after fermentation[J].J Stored Product Res,2013,52(1):42-47.
[11]刘付香,李玲,梁炫强.生物防治黄曲霉毒素污染研究进展[J].中国生物防治学报,2010,26(1):96-101.
[12]李建玲,吴星星.牛奶中霉菌毒素检测方法的研究进展[J].新疆畜牧业,2014(4):16-19.
[13]Kuilman M E,Maas R F,Finkgremmels J.Cytochrome P450-mediated metabolism and cytotoxicity of aflatoxin B(1)in bovine hepatocytes[J].Toxicology In Vitro,2000,14(4):321-327.
[14]孙安权.霉菌毒素对奶牛生产的危害及控制方案[C].南京:中国畜牧兽医学会养牛学分会2009年学术研讨会,2009.
[15]中华人民共和国国家质量监督检验检疫局,中国国家标准化管理委员会.GB 13078-2017饲料卫生标准[S].北京:中国标准出版社,2017..
[16]康影.奶牛玉米赤霉烯酮中毒的诊治[J].畜牧兽医科技信息,2016(3):56.
[17]The European Food safety Authority.Opinion of the scientific panel on contaminants in food chain on a request from the commission related to fusarium as undesirable substance in animal feed[M].Italy:The European Food safety Authority,2005:1-32.
[18]Whitlow L W,Hagler W M.Mycotoxins:A Review of Dairy Concerns[A].Mid-South Ruminant Nutrition Conference[C].Raleigh:North Carolina State University,2005:47-58.
[19]Alberto Gimeno,王琦,任东东,等.霉菌毒素对奶牛的不良影响[J].中国乳业,2010(7):34-37.
[20]高亚男,王加启,郑楠.牛奶中霉菌毒素来源、转化及危害[J].动物营养学报,2017,29(1):34-41.
[21]Alberts J F,Gelderblom W C A,Botha A,et al.Degradation of aflatoxin B1 by fungal laccase enzymes[J].Int J Food Microbiol,2009,135(1):47-52.
[22]丁炜.黄曲霉毒素解毒酶基因的克隆与表达研究[D].呼和浩特:内蒙古农业大学,2010.
[23]Gao X,Ma Q,Zhao L,et al.Isolation of Bacillus subtilis:screening for aflatoxins B 1,M 1,and G 1,detoxification[J].Eur Food Res Technol,2011,232(6):957.
[24]Kakeya H,Takahashi-ando N,Kimura M,et al.Biotra-nsformation of the mycotoxin,zearalenone,to a non-estrogenic compound by a fungal strain of Clonostachys sp.[J].Bicsci Biotechnol Biochem J,2002,66(12):2723-2726.
[25]Takahashiando N,Kimura M,Kakeya H,et al.A novel lactonohydrolase responsible for the detoxification of zearalenone:enzyme purification and gene cloning[J].Biochem J,2002,365(1):1-6.
[26]Vekiru E,Hametner C,Mitterbauer R,et al.Cleavage of zearalenone by Trichosporon mycotoxinivorans to a novel nonestrogenic metabolite.[J].Appl Environ Microb,2010,76(7):2353-2359.
[27]Kiessling K H,Pettersson H,Sandholm K,et al.Metabolism of aflatoxin,ochratoxin,zearalenone,and three trichothecenes by intact rumen fluid,rumen protozoa,and rumen bacteria.[J].Appl Environ Microb 1984,47(5):1070-1073.
[28]Schatzmayr G,Zehner F,T?ubel M,et al.Microbiologicals for deactivating mycotoxins[J].Mol Nutr Food Res,2006,50(6):543-551.
[29]Avantaggiato G,Havenaar R A.Assessing the zearalenonebinding activity of adsorbent materials during passage through a dynamic in vitro gastrointestinal model[J].Food Chem Toxicol,2003,41(10):1283-1290.
[30]Devreese M,Osselaere A,Goossens J,et al.New bolus models for in vivo efficacy testing of mycotoxin-detoxifying agents in relation to EFSA guidelines,assessed using deoxynivalenol in broiler chickens[J].Food Addit Cont,2012,29(7):1101-1107.
[31]梁晓维,李发弟,张军民,等.蒙脱石和凹凸棒石对霉菌毒素吸附性能的研究[J].中国畜牧兽医,2014,41(11):133-138.
[32]朱佳廷,冯敏,严建民,等.辐照对稻米中黄曲霉毒素的降解效果[J].江苏农业科学,2012,40(12):324-326.
[33]罗小虎,齐丽君,房文苗,等.电子束辐照降解玉米中黄曲霉毒素B1及对玉米品质的影响[J].食品与机械,2016,32(10):111-114.
[34]迟蕾.玉米中赭曲霉毒素A辐照降解技术研究[D].北京:中国农业科学院,2011.
[2]冯艳忠,沈伟,王兆山,等.霉菌毒素的研究进展[J].饲料工业,2014,35(4):58-62.
[3]陈波.霉菌毒素对奶牛的危害及防治[J].中国乳业,2013(10):26-28.
[4]Iheshiulor O O M,Esonu B O,Chuwuka O K,et al.Effects of mycotoxins in animal nutrition:A review[J].Asian-Austra JAnim Sci,2011,5(1):19-33.
[5]刘凤芝,李锋,王永丽.2017年上半年我国部分地区饲料及饲料原料中霉菌毒素的污染状况分析[J].粮食与饲料工业,2017(11):46-50.
[6]李孟孟,翟双双,王文策,等.饲料中霉菌毒素的危害及其降解方法研究进展[J].中国家禽,2016,38(5):37-41.
[7]欧阳富龙,彭媛媛,张光磊,等.饲料原料中常见霉菌毒素的危害及处理[J].中国畜牧业,2017(1):60-62.
[8]孙永明.饲料中常见霉菌毒素及产生原因[J].上海畜牧兽医通讯,2012(3):86.
[9]Ding X,Li P,Bai Y,et al.Aflatoxin B 1,in post-harvest peanuts and dietary risk in China[J].Food Control,2012,23(1):143-148.
[10]Keller L A M,Pereyra M L G,Keller K M,et al.Fungal and myc-otoxins contamination in corn silage:Monitoring risk before and after fermentation[J].J Stored Product Res,2013,52(1):42-47.
[11]刘付香,李玲,梁炫强.生物防治黄曲霉毒素污染研究进展[J].中国生物防治学报,2010,26(1):96-101.
[12]李建玲,吴星星.牛奶中霉菌毒素检测方法的研究进展[J].新疆畜牧业,2014(4):16-19.
[13]Kuilman M E,Maas R F,Finkgremmels J.Cytochrome P450-mediated metabolism and cytotoxicity of aflatoxin B(1)in bovine hepatocytes[J].Toxicology In Vitro,2000,14(4):321-327.
[14]孙安权.霉菌毒素对奶牛生产的危害及控制方案[C].南京:中国畜牧兽医学会养牛学分会2009年学术研讨会,2009.
[15]中华人民共和国国家质量监督检验检疫局,中国国家标准化管理委员会.GB 13078-2017饲料卫生标准[S].北京:中国标准出版社,2017..
[16]康影.奶牛玉米赤霉烯酮中毒的诊治[J].畜牧兽医科技信息,2016(3):56.
[17]The European Food safety Authority.Opinion of the scientific panel on contaminants in food chain on a request from the commission related to fusarium as undesirable substance in animal feed[M].Italy:The European Food safety Authority,2005:1-32.
[18]Whitlow L W,Hagler W M.Mycotoxins:A Review of Dairy Concerns[A].Mid-South Ruminant Nutrition Conference[C].Raleigh:North Carolina State University,2005:47-58.
[19]Alberto Gimeno,王琦,任东东,等.霉菌毒素对奶牛的不良影响[J].中国乳业,2010(7):34-37.
[20]高亚男,王加启,郑楠.牛奶中霉菌毒素来源、转化及危害[J].动物营养学报,2017,29(1):34-41.
[21]Alberts J F,Gelderblom W C A,Botha A,et al.Degradation of aflatoxin B1 by fungal laccase enzymes[J].Int J Food Microbiol,2009,135(1):47-52.
[22]丁炜.黄曲霉毒素解毒酶基因的克隆与表达研究[D].呼和浩特:内蒙古农业大学,2010.
[23]Gao X,Ma Q,Zhao L,et al.Isolation of Bacillus subtilis:screening for aflatoxins B 1,M 1,and G 1,detoxification[J].Eur Food Res Technol,2011,232(6):957.
[24]Kakeya H,Takahashi-ando N,Kimura M,et al.Biotra-nsformation of the mycotoxin,zearalenone,to a non-estrogenic compound by a fungal strain of Clonostachys sp.[J].Bicsci Biotechnol Biochem J,2002,66(12):2723-2726.
[25]Takahashiando N,Kimura M,Kakeya H,et al.A novel lactonohydrolase responsible for the detoxification of zearalenone:enzyme purification and gene cloning[J].Biochem J,2002,365(1):1-6.
[26]Vekiru E,Hametner C,Mitterbauer R,et al.Cleavage of zearalenone by Trichosporon mycotoxinivorans to a novel nonestrogenic metabolite.[J].Appl Environ Microb,2010,76(7):2353-2359.
[27]Kiessling K H,Pettersson H,Sandholm K,et al.Metabolism of aflatoxin,ochratoxin,zearalenone,and three trichothecenes by intact rumen fluid,rumen protozoa,and rumen bacteria.[J].Appl Environ Microb 1984,47(5):1070-1073.
[28]Schatzmayr G,Zehner F,T?ubel M,et al.Microbiologicals for deactivating mycotoxins[J].Mol Nutr Food Res,2006,50(6):543-551.
[29]Avantaggiato G,Havenaar R A.Assessing the zearalenonebinding activity of adsorbent materials during passage through a dynamic in vitro gastrointestinal model[J].Food Chem Toxicol,2003,41(10):1283-1290.
[30]Devreese M,Osselaere A,Goossens J,et al.New bolus models for in vivo efficacy testing of mycotoxin-detoxifying agents in relation to EFSA guidelines,assessed using deoxynivalenol in broiler chickens[J].Food Addit Cont,2012,29(7):1101-1107.
[31]梁晓维,李发弟,张军民,等.蒙脱石和凹凸棒石对霉菌毒素吸附性能的研究[J].中国畜牧兽医,2014,41(11):133-138.
[32]朱佳廷,冯敏,严建民,等.辐照对稻米中黄曲霉毒素的降解效果[J].江苏农业科学,2012,40(12):324-326.
[33]罗小虎,齐丽君,房文苗,等.电子束辐照降解玉米中黄曲霉毒素B1及对玉米品质的影响[J].食品与机械,2016,32(10):111-114.
[34]迟蕾.玉米中赭曲霉毒素A辐照降解技术研究[D].北京:中国农业科学院,2011.