Bioactive proteins and peptides isolated from Chinese medicines with pharmaceutical potential

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• 作者：Kam Lok Wong (1)
  Ricky Ngok Shun Wong (2)
  Liang Zhang (1)
  Wing Keung Liu (3)
  Tzi Bun NG (3)
  Pang Chui Shaw (4)
  Philip Chi Lip Kwok (5)
  Yau Ming Lai (6)
  Zhang Jin Zhang (1)
  Yanbo Zhang (1)
  Yao Tong (1)
  Ho-Pan Cheung (1)
  Jia Lu (1)
  Stephen Cho Wing Sze (1)
  
  1. School of Chinese Medicine ; LKS Faculty of Medicine ; The University of Hong Kong ; 10 Sassoon Road ; Pokfulam ; Hong Kong Special Administrative Region ; China
  2. Department of Biology ; Faculty of Science ; Hong Kong Baptist University ; Hong Kong Special Administrative Region ; China
  3. School of Biomedical Sciences ; Faculty of Medicine ; The Chinese University of Hong Kong ; Shatin ; N.T. ; Hong Kong Special Administrative Region ; China
  4. School of Life Sciences and Centre for Protein Science and Crystallography ; Faculty of Science ; The Chinese University of Hong Kong ; Shatin ; N.T. ; Hong Kong Special Administrative Region ; China
  5. Department of Pharmacology & Pharmacy ; LKS Faculty of Medicine ; The University of Hong Kong ; Pokfulam ; Hong Kong Special Administrative Region ; China
  6. Department of Health Technology and Informatics ; Hong Kong Polytechnic University ; Hung Hom ; Hong Kong Special Administrative Region ; China
  
• 刊名：Chinese Medicine
• 出版年：2014
• 出版时间：December 2014
• 年：2014
• 卷：9
• 期：1
• 全文大小：2,459 KB
• 参考文献：1. Global markets and manufacturing technologies for protein drugs [http://www.bccresearch.com/market-research/biotechnology/protein-drugs-therapeutics-bio021d.html]
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• 刊物主题：Complementary & Alternative Medicine;
• 出版者：BioMed Central
• ISSN：1749-8546

文摘

Some protein pharmaceuticals from Chinese medicine have been developed to treat cardiovascular diseases, genetic diseases, and cancer. Bioactive proteins with various pharmacological properties have been successfully isolated from animals such as Hirudo medicinalis (medicinal leech), Eisenia fetida (earthworm), and Mesobuthus martensii (Chinese scorpion), and from herbal medicines derived from species such as Cordyceps militaris, Ganoderma, Momordica cochinchinensis, Viscum album, Poria cocos, Senna obtusifolia, Panax notoginseng, Smilax glabra, Ginkgo biloba, Dioscorea batatas, and Trichosanthes kirilowii. This article reviews the isolation methods, molecular characteristics, bioactivities, pharmacological properties, and potential uses of bioactive proteins originating from these Chinese medicines.