A New Graphene Derivative: Hydroxylated Graphene with Excellent Biocompatibility

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• 作者：Jing Sun ; Yuan Deng ; Jipeng Li ; Gang Wang ; Peng He ; Suyun Tian ; Xiuming Bu ; Zengfeng Di ; Siwei Yang ; Guqiao Ding ; Xiaoming Xie
• 刊名：ACS Applied Materials & Interfaces
• 出版年：2016
• 出版时间：April 27, 2016
• 年：2016
• 卷：8
• 期：16
• 页码：10226-10233
• 全文大小：598K
• 年卷期：0
• ISSN：1944-8252

文摘

Graphene derivatives (such as graphene oxide and hydrogenated graphene) have been widely investigated because of their excellent properties. Here, we report large-scale (kilogram scale) synthesis of a new unique graphene derivative: hydroxylated graphene (G-OH). The exclusive existence form of oxygen-containing groups in G-OH is hydroxyl, which was verified by spectral characterization and quantitative halogenating reaction. It is very interesting that both the wettability and electrical conductivity show reversible change in halogenating and hydrolysis reaction cycles, which demonstrates the versatility of G-OH. Most importantly, the hydrophilicity and weak inductive nature of G-OH provides a well microenvironment for the cells adhesion and proliferation. On G-OH paper, rat adipose tissue-derived stromal cells exhibited a typical fibroblast-like shape with high rate of increase and survival after 3 day of incubation. This G-OH paper with good mechanical property is expected to be a new biomaterial for bone, vessel and skin regeneration.