Copper-Catalyzed Oxyazidation of Unactivated Alkenes: A Facile Synthesis of Isoxazolines Featuring an Azido Substituent

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• 作者：Liping Zhu ; Hongmei Yu ; Zhaoqing Xu ; Xianxing Jiang ; Li Lin ; Rui Wang
• 刊名：Organic Letters
• 出版年：2014
• 出版时间：March 21, 2014
• 年：2014
• 卷：16
• 期：6
• 页码：1562-1565
• 全文大小：263K
• 年卷期：v.16,no.6(March 21, 2014)
• ISSN：1523-7052

文摘

A novel and efficient Cu(OAc)₂-catalyzed oxyazidation of unactivated alkenes was developed. The reactions are easy to conduct, occur under mild conditions, and form azido-substituted isoxazolines in good yields.