Transition-Metal-Free Oxidative Aliphatic C鈥揌 Azidation

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• 作者：Xiaofei Zhang ; Haodong Yang ; Pingping Tang
• 刊名：Organic Letters
• 出版年：2015
• 出版时间：December 4, 2015
• 年：2015
• 卷：17
• 期：23
• 页码：5828-5831
• 全文大小：385K
• ISSN：1523-7052

文摘

The first example of a practical and selective azidation of unactivated aliphatic C鈥揌 bonds with easily handled sulfonyl azides as azide source without the use of transition metals has been explored. This method is operationally simple, scalable, and applicable to late-stage azidation of natural products and derivatives, which make it a valuable method for the synthesis of organic azides.