Expression levels of the receptor activator of NF-κB ligand and osteoprotegerin and the number of gram-negative bacteria in symptomatic and asymptomatic periapical lesions

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• 作者：E. Carneiro ; DDS ; MS ; PhD^a ; ^{everdan.carneiro@pucpr.br} ; A.B. Parolin ; DDS ; MS^a ; C. Wichnieski ; DDS ; MS^a ; E.A.R. Rosa ; MS ; PhD^b ; U.X. Silva Neto ; DDS ; MS ; PhD^a ; V.P.D. Westphalen ; DDS ; MS ; PhD^a ; L.F. Fariniuk ; DDS ; MS ; PhD^a ; A.C.B.R. Johann ; DDS ; MS ; PhD^c
• 关键词：Gram-negative bacteria ; RANKL ; OPG ; Apical periodontitis ; Symptomatic
• 刊名：Archives of Oral Biology
• 出版年：2017
• 出版时间：January 2017
• 年：2017
• 卷：73
• 期：Complete
• 页码：166-171
• 全文大小：2271 K
• 卷排序：73

文摘

We examine the expression of RANKL and OPG in patients with symptomatic apical periodontitis. We correlate the results with the detected numbers of gram-negative bacteria. The symptomatic group showed a significantly higher number of gram-negative cells. Gram-negative bacteria may play an important role in OPG activity in patients with symptomatic apical periodontitis. A higher number of gram-negative bacteria occurred more frequently in larger periapical lesions and SYM group.