///This paper discusses uplifting-denudation and exposure history and paleotopographic reconstruction of Altay region based on fission track technology. AFT data from 11 samples show that the AFTA range from 99.2 to 43.7 Ma.The average denudation and exposure rate has been 0.050 mm/ma since Late Cretaceous.Thermal history modeling results show that there have been multi-phase cooling and denudation and exposure evolutions since the Cretaceous period in the south margin of the Altay Mountains. Paleotopographic reconstruction of the study area shows that the average denudation and exposure highness from Cretaceous up till now is about 5 km, while paleoelevation has been decreased by about 0.8 km. Cretaceous-Cenozoic paleoelevation of the south range of Altay Mountains has tended to decrease except for a stable period of 50~17.5 Ma.