Maoping tungsten deposit is a large W-Sn-polymetallic deposit discovered recently in southern Jiangxi Province. This paper studies the fluid inclusions in quartz and topaz occurring in wolframite-quartz-veins, which mainly includes microthermometry and Laser Raman analysis. The results show that fluid inclusions in both quartz and topaz are mainly liquid-rich two-phase aqueous solution (H2O-NaCl), in addition to small amount of CO2 -bearing three-phase aqueous solution in quartz. The characteristics of homogenization temperatures and salinities from fluid inclusions in quartz reveal multiple-stages of ore-forming process and the complexity of fluid evolution. It is concluded from fluid inclusions that the early-stage boiling and late-stage mixing are probably the major mechanism of formation of wolframite-quartz-vein type ore in the Maoping deposit.