地震创伤失血性休克的容量复苏
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摘要
目的探讨院前创伤失血性休克的容量复苏治疗方法。方法回顾性分析2008年‘5.12’地震期间我院680例未控制出血的休克患者的容量复苏方法,比较常规液体复苏组(320例)和限制性液体复苏组(360例)以及7.5%高渗氯化钠组(180例)的治愈率、多脏器功能衰竭(MODS)、急性呼吸窘迫综合征(ARDS)的发生率及病死率。结果常规液体复苏组治愈率为62.5%(200/320),病死率37.5%(120/320),ARDS发生率为20.9%(67/320),MODS发生率30.9%(99/320);限制性液体复苏组治愈率为82.8%(298/360),病死率17.2%(62/360),ARDS发生率为8.9%(32/360),MODS发生率为17.5%(63/360),2组比较差异有统计学意义(P<0.05)。限制性液体复苏组中7.5%高渗氯化钠组治愈率为86.6%(156/180),病死率13.4%(24/180),ARDS发生率为3.3%(6/180),MODS发生率为9.4%(17/180)。结论限制性液体复苏治疗,特别是7.5%高渗氯化钠更能减少未控制出血性休克患者MODS和ARDS的发生率,提高其治愈率。
objective To explore the effect of limited volume resuscitation of uncontrolled hemorrhagic traumatic shock.Methods 680 cases were retrospectively analyzed.The healing rate incid ence of MOD S and ARDS And mortality rate between regular fluid resuscitation group and limited fluid resuscitation group,and ebtween 7.5% hypertonic saline fluid resuscitation group and lacatate Ringer's fluid resuscitation group were compared.Results Survival rate of regular volume resuscitation group was 62.5%,mortality rate was 37.5%,in idence of ARDS was 20.9%,incidence of MODS was 30.9%.There was statistical significance between two groups(P<0.05).Survival rate of 7.5%hypertonic saline fluid resuscitation group was 86.6%,mortality rate was 13.4%,incidence of MODS was 9.4%,incidence of ARDS was 3.3%.Conclusion Limited volume resuscitation especially 7.5% hypertonic saline volume resuscitation is more rational to improve the prognosis of patients with uncontrolled traumatic shock than regular volume resuscitation.
引文
1王钦存.限制性液体复苏对出血未控制休克后续救治的影响[J].中国实用外科杂志,2004,24(6):354.
    2陈晓雄,叶恭水,帅学军,等.重症胸部创伤合并创伤失血性体克限制性液体复苏的疗效评价[J].中国急救医学,2004,3:178-180.
    3沈洪.创伤早期液体复苏的利与弊[J].中华急诊医学杂志,2002,11(2):136.

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