重金属对鱼类的生态毒理学研究进展
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摘要
水体重金属污染是目前日益严重的环境问题之一,随着工农业的发展,生产生活中的重金属可以通过多种途径进入水生态系统。水生态系统重金属污染具有来源广泛、易在生物体内蓄积、不易分解的特点,不仅对水生生物各类群及整个生态系统产生影响,还可以通过食物链间接危害人类健康,重金属对水生态系统的影响及其对水生生物毒理学研究已成为全球环境研究的热点。鱼类作为水生态系统重要的组成部分,近年来国内外针对重金属及其生态毒理学开展了大量的研究工作。在总结分析国内外研究的基础上,综述了鱼类重金属的来源、赋存和迁移转化规律,阐述了重金属对鱼类个体水平、细胞水平、分子和遗传水平的毒理学效应以及鱼类对重金属的耐受机制;并结合重金属对鱼类生态毒理学研究中不足,对未来可能的研究方向进行了展望。
With the development of industry and agriculture, heavy metals enter the aquatic ecosystem in a variety of ways, and heavy metal pollution in water has become an increasingly serious environmental problem. Heavy metals do not decompose, tending to accumulate in the sediments of aquatic ecosystems and bioaccumulate as they move up the food chain, threatening ecological and human health. Thus, the effects of heavy metal contamination on aquatic ecosystems and their toxic mechanisms are of great interest, worldwide, to environmental researchers. In this study, we analyze and summarize research progress on the ecotoxicology of heavy metals in fish: sources and sinks; speciation and environmental transformation; migration and distribution of heavy metals in fish; effects of heavy metal exposure on fish at the organismal, cellular, molecular and genetic levels; and tolerance mechanisms of fish to heavy metals. Finally, we discuss the deficiencies of current research and the future of research on fish ecotoxicology.
With the development of industry and agriculture, heavy metals enter the aquatic ecosystem in a variety of ways, and heavy metal pollution in water has become an increasingly serious environmental problem. Heavy metals do not decompose, tending to accumulate in the sediments of aquatic ecosystems and bioaccumulate as they move up the food chain, threatening ecological and human health. Thus, the effects of heavy metal contamination on aquatic ecosystems and their toxic mechanisms are of great interest, worldwide, to environmental researchers. In this study, we analyze and summarize research progress on the ecotoxicology of heavy metals in fish: sources and sinks; speciation and environmental transformation; migration and distribution of heavy metals in fish; effects of heavy metal exposure on fish at the organismal, cellular, molecular and genetic levels; and tolerance mechanisms of fish to heavy metals. Finally, we discuss the deficiencies of current research and the future of research on fish ecotoxicology.
引文
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丁磊,吴萍,蔡春芳,等,2004.Cd对鲫血清溶菌酶和过氧化物酶的影响[J].农业环境科学学报,23(2):243-245.
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郭勇勇,华江环,杨丽华,等,2015.三峡库区水样中重金属含量及其对斑马鱼胚胎发育的毒性评价[J].水生生物学报,39(5):885-892.
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李嗣新,胡菊香,池仕运,等,2016.汞在新建水库食物网中生物累积与风险评价研究进展[J].生态学报,36(5):1233-1243.
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李健,2016.长江上游15种常见鱼类体内5种重金属含量及水体镉暴露对南方鲇生态毒理学效应[D].重庆:西南大学.
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刘艳平,李炼,李忠魁,等,2003.底泥重金属镉对鳙鱼血细胞微核率的影响[J].实用预防医学,10(4):485-487.
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潘天扬,房树林,闫玉莲,等,2016.水体中铅对长江上游6种鱼类的急性中毒效应[J].淡水渔业,46(3):34-39.
任洪涛,林霖,2016.不同浓度 Cd2+对草鱼组织器官及抗氧化酶SOD活性的影响[J].江苏农业科学,44(11):261-263.
任洪涛,张春暖,林霖,2017.Mo6+对草鱼组织器官及抗氧化酶活性的影响[J].水产科学,36(3):317-322.
沈梦楠,康春玉,李娜,等,2018.长春市市售9种鱼类中重金属含量分析及健康风险评价[J].淡水渔业,48(4):95-100.
宋思祺,鞠瑞营,杜欣羽,等,2017.重金属铅和汞对斑马鱼胚胎的毒性及抗氧化酶活性的影响[J].畜牧与饲料科学,38(7):5-9.
田林锋,胡继伟,罗桂林,等,2012.贵州百花湖鱼体器官及肌肉组织中重金属的分布特征及其与水体重金属污染水平的相关性[J].水产学报,36(5):714-722.
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王燕,李贤庆,宋志宏,等,2009.土壤重金属污染及生物修复研究进展[J].安全与环境学报,9(3):60-65.
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徐永江,柳学周,马爱军,2004.重金属对鱼类毒性效应及其分子机理的研究概况[J].海洋科学,(10):67-70.
翟毓秀,杨学宋,宁劲松,等,2005.镉在大菱鲆体内蓄积规律及对生长和食品安全影响初探[J].海洋水产研究,(4):26-31.
张迎梅,王叶菁,虞闰六,等,2006.重金属Cd2+、Pb2+和Zn2+对泥鳅DNA损伤的研究[J].水生生物学报,30(4):399-403.
赵光辉,常文越,刘智,等,2018.水体重金属在斑马鱼(Danio rerio)组织中的累积及对抗氧化系统的影响——以浑河为例[J].安徽农业科学,46(12):77-80,101.
赵汉取,施沁璇,沈萍萍,等,2014.低浓度Cd2+胁迫对青鱼组织SOD活性和MT诱导的影响[J].水生态学杂志,35(2):90-94.
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郭勇勇,华江环,杨丽华,等,2015.三峡库区水样中重金属含量及其对斑马鱼胚胎发育的毒性评价[J].水生生物学报,39(5):885-892.
贾秀英,陈志伟,2003.铜、镉对鲫组织超氧化物歧化酶活性的影响[J].水生生物学报,27(3):323-325.
李嗣新,胡菊香,池仕运,等,2016.汞在新建水库食物网中生物累积与风险评价研究进展[J].生态学报,36(5):1233-1243.
李华,2013.重金属在淡水鱼体内的蓄积、排出机理及其金属硫蛋白的研究[D].哈尔滨:东北农业大学.
李健,2016.长江上游15种常见鱼类体内5种重金属含量及水体镉暴露对南方鲇生态毒理学效应[D].重庆:西南大学.
李小云,王丽萍,2009.重金属锌在鱼鳃和鱼肉中的积累[J].光谱实验室,26(2):265-268.
刘艳平,李炼,李忠魁,等,2003.底泥重金属镉对鳙鱼血细胞微核率的影响[J].实用预防医学,10(4):485-487.
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罗其勇,2018.重金属暴露引起鱼体氧化应激反应的研究进展[J].安徽农业科学,46(25):32-35.
潘天扬,房树林,闫玉莲,等,2016.水体中铅对长江上游6种鱼类的急性中毒效应[J].淡水渔业,46(3):34-39.
任洪涛,林霖,2016.不同浓度 Cd2+对草鱼组织器官及抗氧化酶SOD活性的影响[J].江苏农业科学,44(11):261-263.
任洪涛,张春暖,林霖,2017.Mo6+对草鱼组织器官及抗氧化酶活性的影响[J].水产科学,36(3):317-322.
沈梦楠,康春玉,李娜,等,2018.长春市市售9种鱼类中重金属含量分析及健康风险评价[J].淡水渔业,48(4):95-100.
宋思祺,鞠瑞营,杜欣羽,等,2017.重金属铅和汞对斑马鱼胚胎的毒性及抗氧化酶活性的影响[J].畜牧与饲料科学,38(7):5-9.
田林锋,胡继伟,罗桂林,等,2012.贵州百花湖鱼体器官及肌肉组织中重金属的分布特征及其与水体重金属污染水平的相关性[J].水产学报,36(5):714-722.
王凡,刘海芳,张水土,等,2011.镉污染对鲤超氧化物歧化酶活性的影响[J].水生态学杂志,32(1):115-117.
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王田田,魏瑞霞,安晓佳,等,2015.重金属铅在鲫鱼体内的积蓄效应[J].河北联合大学学报(自然科学版),37(4):122-126.
王文君,易雨君,张尚弘,等,2019.长江中下游鱼类重金属污染及健康风险评价[J].水利水电技术,(2):8-13.
王文雄,2011.微量金属生态毒理学和生物地球化学[M].北京:科学出版社.
王燕,李贤庆,宋志宏,等,2009.土壤重金属污染及生物修复研究进展[J].安全与环境学报,9(3):60-65.
韦蔓新,何本茂,2004.钦州湾近20a来水环境指标的变化趋势Ⅲ:微量重金属的含量分布及其来源分析[J].海洋环境科学,23(1):29-32.
徐永江,柳学周,马爱军,2004.重金属对鱼类毒性效应及其分子机理的研究概况[J].海洋科学,(10):67-70.
翟毓秀,杨学宋,宁劲松,等,2005.镉在大菱鲆体内蓄积规律及对生长和食品安全影响初探[J].海洋水产研究,(4):26-31.
张迎梅,王叶菁,虞闰六,等,2006.重金属Cd2+、Pb2+和Zn2+对泥鳅DNA损伤的研究[J].水生生物学报,30(4):399-403.
赵光辉,常文越,刘智,等,2018.水体重金属在斑马鱼(Danio rerio)组织中的累积及对抗氧化系统的影响——以浑河为例[J].安徽农业科学,46(12):77-80,101.
赵汉取,施沁璇,沈萍萍,等,2014.低浓度Cd2+胁迫对青鱼组织SOD活性和MT诱导的影响[J].水生态学杂志,35(2):90-94.
Ajima M N,Nnodi P C,Ogo O A,et al,2015.Bioaccumulation of heavy metals in Mbaa River and the impact on aquatic ecosystem[J].Environmental Monitoring & Assessment,187(12):1-9.
Bahnasawy M,Khidr A A,Dheina N,2014.Assessment of heavy metal concentrations in water,plankton,and fish of Lake Manzala,Egypt[J].Turkish Journal of Zoology,35(2):271-280.
Barbosa J S,Cabral T M,Ferreira D N,et al,2010.Genotoxicity assessment in aquatic environment impacted by the presence of heavy metals[J].Ecotox Environ Safe,73(3):320-325.
Campbell P G C,Giguere A,Bonneris E,et al,2005.Cadmium-handling strategies in two chronically exposed indigenous freshwater organisms-the yellow perch (Perca flavescens) and the floater mollusc (Pyganodon grandis) [J].Aquatic Toxicology,72(1):83-97.
Chatta A M,Khan M N,Mirza Z S,et al,2016.Heavy metal (cadmium,lead,and chromium) contamination infarmed fish:a potential risk for consumers' health[J].Turkish Journal of Zoology,40:248-256.
Chen C Y,Pickhardt P C,Xu M Q,et al,2008.Mercury and Arsenic Bioaccumulation and Eutrophication in Baiyangdian Lake,China[J].Water Air Soil Pollut,190(1/4):115-127.
Daly H R,Campbell I C,Hart B T,2010.Copper toxicity to Paratya australiensis:I.Influence of nitrilotriacetic acid and glycine[J].Environmental Toxicology & Chemistry,9(8):997-1006.
Devlin E W,2006.Acute toxicity,uptake and histopathology of aqueous methyl mercury to fathead minnow embryos[J].Ecotoxicology,15(1):97-110.
Dudley R E,Klaassen C D,1984.Changes in hepatic glutathione concentration modify cadmium-induced hepatotoxicity[J].Toxicology & Applied Pharmacology,72(3):530-538.
Endo T,Yoshikawa M,Ebara M,et al,2005.Immunohistochemical metallothionein expression in hepatocellular carcinoma:relation to tumor progression and chemoresistance to platinum agents[J].Journal of Gastroenterology,39(12):1196-1201.
Gao Y F,Kang L L,Zhang Y,et al,2019.Toxicokinetic and toxicodynamic (TK-TD) modeling to study oxidative stress-dependent toxicity of heavy metals in zebrafish[J].Chemosphere,220:774-782.
Giaginis C,Gatzidou E,Theocharis S,2006.DNA repair systems as targets of cadmium toxicity[J].Toxicol Appl Pharmacol,213(3):282-290.
Hamza-Chaffai A,Amiard JC,Pellerin J,et al,2000.The potential use of metallothionein in the clam Ruditapes decussatus as a biomarker of in situ metal exposure[J].Comparative Biochemistry and Physiology Part C:Comparative Pharmacology and Toxicology,127(2):185-197.
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