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宁心固泄汤治疗阴虚阳亢型早泄的临床观察
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摘要
目的:通过观察中药“宁心固泄汤”治疗阴虚阳亢型早泄的临床疗效,并对治疗后患者的射精潜伏期、患者及其配偶对性生活的满意程度等指标的变化情况进行比较研究,为临床采用中医药治疗早泄提供一条有效的途径。
     方法:将符合诊断标准,中医辨证属于阴虚阳亢证候的90例患者,随机分为治疗组、对照组Ⅰ和对照组Ⅱ。治疗组30例,口服“宁心固泄汤”治疗;对照组Ⅰ30例,口服美抒玉治疗;对照组Ⅱ30例,口服知柏地黄丸治疗。以上三组均以4周为一疗程,每7天复诊一次,疗程结束时统计疗效。观察治疗期间,要求停用其它有关药物及治疗方法,性生活时间、频率、方法及习惯等保持不变,但给予必要的正确性技巧指导。疗程结束后随访3个月,最终观察:治疗后患者的射精潜伏期、患者及其配偶对性生活的满意程度,并记录药物副作用。
     结果:1.治疗组与对照组Ⅰ、对照组Ⅱ的平均射精潜伏期比较,有明显差异(P<0.05),治疗组在延长患者射精潜伏期方面明显优于对照组Ⅰ、Ⅱ,说明“宁心固泄汤”能明显延长患者的射精潜伏期;2.治疗组与对照组Ⅰ、对照组Ⅱ的配偶的平均满意度比较,有明显差异(P<0.05),治疗组在提高配偶对性生活的满意程度方面明显优于对照组Ⅰ、Ⅱ,说明“宁心固泄汤”能明显提高患者配偶对性生活的满意度;3.治疗组与对照组Ⅰ、对照组Ⅱ的治疗起效时间比较,有明显差异(P<0.05),治疗组2周后起效病例数明显多于对照组Ⅰ、Ⅱ,说明“宁心固泄汤”能明显加快起效时间;4.治疗组与对照组Ⅰ、对照组Ⅱ的患者对性生活满意的病例比较,有极显著差异(P<0.01),治疗组明显优于对照组Ⅰ、Ⅱ;5.治疗组与对照组Ⅰ、对照组Ⅱ的近期治愈率及总有效率比较,均有明显差异(P<0.05),说明治疗组的近期治愈率及总有效率明显优于对照组Ⅰ、Ⅱ。其中,治疗组近期治愈率53.3%,总有效率93.3%,对照组Ⅰ近期治愈率30.0%,总有效率76.7%。对照组Ⅱ近期治愈率23.3%,总有效率73.3%。
     另外,需要说明的是,三组患者随着的射精潜伏期的延长,患者自信心得到增强,患者对性生活的紧张、焦虑情绪得到了明显缓解,并大大提高了对射精的控制能力,其中以治疗组改善更加明显。
     结论:中药“宁心固泄汤”治疗阴虚阳亢型早泄的疗效明显优于对照组Ⅰ、Ⅱ,能明显延长患者的射精潜伏期,提高患者及其配偶对性生活的满意程度,改善患者对射精的控制能力,缓解焦虑、紧张情绪以及减低药物副作用。
Objective:Through observating the clinical effect of traditional chinese medicine "Ningxinguxietang" treating premature ejaculation with yin deficiency and yang excess,to observe ejaculation latency of patients,satisfaction of patients and their spouses on the sexual life after treatment,et al,and to find a new therapy of premature ejaculation with traditional chinese medicine.
     Methods:Choosing 90 cases of patients,who were patients with syndrome of yin deficiency and yang excess,were randomized into treatment group and control groupⅠandⅡ.The treatment group was used "Ningxinguxietang";the control groupⅠ:taking Trazodone hydrochloride tablets;the control groupⅡ:taking Zhibaidihuangwan.Four weeks was a course of medical treatment,seven days was a referral.The results were analysized and statisted at the end of treatment.During treatment,requiring to suspend other relevant medicines and therapy;Time,frequency,methods and habits of sex life were remained,but given the necessary guidance of accuracy skills.After treatment,three groups were followed up and detected ejaculation latency,satisfaction of patients and their spouses on the sexual life, and wrote down medicine side effect during three months.
     Results:1.The average ejaculation latency of the treatment group,control groupⅠandⅡhad more significant difference(P<0.05),the average ejaculation latency of the treatment group was obviously superior to the control groupⅠandⅡ.It showed that traditional chinese medicine "Ningxinguxietang" could significantly prolong ejaculation latency of Patients.2. The average satisfaction of their spouse in the three groups,had more significant differences (P<0.05),The treatment group increased satisfaction of their spouses on the sexual life,which was superior to the control groupⅠandⅡ.It showed that "Ningxinguxietang" could significantly improve the satisfaction of their spouses.3.The onset time of treatment in the three groups had more significant difference(P<0.05).In the treatment group,the number of cases rising in two weeks was higher than the control groupⅠandⅡ.It showed that "Ningxinguxietang "could obviously accelerate the onset time.4.The satisfaction of patients in the three groups had significant difference(P<0.01),the treatment group was significantly better than the control groupⅠandⅡ.5.The recent cure rate in the three groups had significant differences(P<0.05).The recent cure rate and the total efficiency of the treatment group were better than the control groupⅠandⅡ.The recent cure rate of the treatment group was 53.3%,and the total efficiency was 93.3%.In the control groupⅠ,the recent cure rate was 30.0%,the total efficiency was 76.7%.In the control groupⅡ,the recent cure rate was 23.3%, and the total efficiency was 73.3%.
     In addition,it was stated that patients in the three groups were with the extension of the ejaculation latency,their self-confidence had been strengthened,the tension and anxiety of the sexual life had been significantly eased,and the control ability to ejaculation had been greatly enhanced,and the treatment group was best in three groups.
     Conclusion:By using traditional chinese medicine "Ningxinguxietang" to treat premature ejaculation with syndrome of yin deficiency and yang excess,the treatment group was superior to the control groupⅠandⅡ.It could significantly prolong ejaculation latency and improve satisfaction of patients and their spouses on the sexual life,even could improve the control ability to ejaculation,ease tension anxiety,and reduce medicine side effect.
引文
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