Ti-25Nb-2Zr合金表面微孔结构的构建
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摘要
本文利用阳极氧化的方法,在Ti-25Nb-2Zr合金表面构建了微孔结构,在1.5倍模拟体液中考察了其生物活性。采用扫描电镜(SEM)、X射线衍射(XRD)、红外光谱(FT-IR)以及X射线光电子能谱(XPS)对合金表面的多孔氧化膜结构和仿生生长后表面的Ca-P层进行了表征。
结果表明:微孔的形貌随电解液成分变化而改变,当电解液为硫酸时,微孔呈沟槽状,而当电解液改为1mol/L H_3PO_4(200ml)+2g NH_4F时,所形成的微孔为纳米级的排列整齐的圆形小孔;在电解液为1mol/L H_3PO_4(200ml)+2g NH_4F的体系中,电压和时间共同影响微孔的形貌,同一电压(时间)下,随着时间(电压)的增大,微孔逐渐由孔洞状向管状转变,且其直径也随之增大;Ti-25Nb-2Zr合金表面的多孔氧化膜结构是由TiO_2+Nb_2O_5+ZrO_2组成的;Ti-25Nb-2Zr合金经过阳极氧化处理后,所得到多孔结构能够诱导磷灰石的沉积,而且随着仿生生长时间的延长,表面Ca-P层厚度增加,结晶度也随之提高;仿生生长后所得到的钙磷层为是含有CO_3~(2-)的羟基磷灰石,即类骨磷灰石。
The porous films were prepared by anodic oxidation on the surface of Ti-25Nb-2Zr alloy. In order to validate the bioactivity of the porous films , the biomimetic growth experiments was carried out in the 1.5 SBF (Simulated Body Fluid). The characteristics of the porous films and the Ca-P coatings prepared by biominmetic growth experiments were investigated by using SEM, XRD, IR, XPS.
The results indicated that the morphology of the porous films were different by using different electrolytes. When sulphuric acid used, the morphology of the porous films was like the shape of channel. Mass of nano-porous films were obtained, when the electrolyte was 1mol/L H_3PO_4(200ml)+2g NH_4F. In the anodic oxidation, the morphology of the porous films were influenced by the voltage and time together. Along with the time (voltage) increasing, the morphology of the porous films gradually changed to nanotube from micropore after the same voltage (time), with the diameter increasing too, The porous films on the surface of Ti-25Nb-2Zr alloy were composed of TiO_2+Nb_2O_5+ZrO_2, Ti-25Nb-2Zr alloy after anodic oxidation had the ability to induce the deposition of the apatite on the surface, and the Ca-P coating went thicker and the crystallinity was enhanced along with the time increasing. The Ca-P coating gained by biomimetic growth in the 1.5 SBF was hydroxyapatite that contained CO_3~(2-), namely the bone-like apatite.
结果表明:微孔的形貌随电解液成分变化而改变,当电解液为硫酸时,微孔呈沟槽状,而当电解液改为1mol/L H_3PO_4(200ml)+2g NH_4F时,所形成的微孔为纳米级的排列整齐的圆形小孔;在电解液为1mol/L H_3PO_4(200ml)+2g NH_4F的体系中,电压和时间共同影响微孔的形貌,同一电压(时间)下,随着时间(电压)的增大,微孔逐渐由孔洞状向管状转变,且其直径也随之增大;Ti-25Nb-2Zr合金表面的多孔氧化膜结构是由TiO_2+Nb_2O_5+ZrO_2组成的;Ti-25Nb-2Zr合金经过阳极氧化处理后,所得到多孔结构能够诱导磷灰石的沉积,而且随着仿生生长时间的延长,表面Ca-P层厚度增加,结晶度也随之提高;仿生生长后所得到的钙磷层为是含有CO_3~(2-)的羟基磷灰石,即类骨磷灰石。
The porous films were prepared by anodic oxidation on the surface of Ti-25Nb-2Zr alloy. In order to validate the bioactivity of the porous films , the biomimetic growth experiments was carried out in the 1.5 SBF (Simulated Body Fluid). The characteristics of the porous films and the Ca-P coatings prepared by biominmetic growth experiments were investigated by using SEM, XRD, IR, XPS.
The results indicated that the morphology of the porous films were different by using different electrolytes. When sulphuric acid used, the morphology of the porous films was like the shape of channel. Mass of nano-porous films were obtained, when the electrolyte was 1mol/L H_3PO_4(200ml)+2g NH_4F. In the anodic oxidation, the morphology of the porous films were influenced by the voltage and time together. Along with the time (voltage) increasing, the morphology of the porous films gradually changed to nanotube from micropore after the same voltage (time), with the diameter increasing too, The porous films on the surface of Ti-25Nb-2Zr alloy were composed of TiO_2+Nb_2O_5+ZrO_2, Ti-25Nb-2Zr alloy after anodic oxidation had the ability to induce the deposition of the apatite on the surface, and the Ca-P coating went thicker and the crystallinity was enhanced along with the time increasing. The Ca-P coating gained by biomimetic growth in the 1.5 SBF was hydroxyapatite that contained CO_3~(2-), namely the bone-like apatite.
引文
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[19]宁聪琴,周玉,医用钛合金的发展及研究现状,材料科学与工艺,2002,10(1):100~106
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[21]Wang K.K., Gustavson L.J., Dumbleton J.H., The characterization of Ti-12Mo-6Zr-2Fe A new alloy developed for surgical implants, Beta Titanium Alloy in the 1990’s, TMS of AIME, 1993: 49~60
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[25]张玉梅,钛及钛合金在口腔应用的研究方向,生物医学工程学杂志,2000,17(2):206~208
[26]李佐臣,周廉,李军,外科植入物用第三代新型医用钛合金研究,钛工业进展,2001,5(20):4~5
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[29]李玉宝,生物医学材料,天津:化学工业出版社,2003,5~8
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