高血压病中医证素与血液流变学指标的相关性研究
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摘要
目的：通过观察高血压病患者血液流变学指标(全血高切[200/S]、全血中切[50/S]、全血低切[5/S]、全血低切[1/S]、全血还原粘度(高切)、全血还原粘度(低切)、全血高切相对粘度、全血低切相对粘度、血浆粘度值、红细胞压积、血沉、血沉方程K值、红细胞刚性指数、红细胞聚集指数、红细胞变形指数、纤维蛋白原)以了解这些指标与高血压病患者各证素(气虚、阴虚、阳亢、痰湿、瘀血)间的相关性。
方法：临床收集符合高血压病西医诊断标准的99例患者进行辨证分组。根据患者含有证素数量的不同分别归入单证素组、二证素组、三证素组、四证素组,在各组内根据证素构成的不同再进行分组,根据证素的虚实属性将其归类,并根据是否含有瘀血证素进行分组。在各组间行血液流变学指标的比较,采用频数分布法进行中医证素分布研究,两组间比较用t检验,探讨各指标与高血压病中医证素间的关系。
结果：
1高血压病证素人群分布比较结果为：高血压病证素数量组合人群分布比较结果为：二证素>单证素>三证素>四证素；高血压病证素类型组合人群分布比较结果为：单证素组为阳亢=痰湿>阴虚>气虚>瘀血,二证素组为阴虚+阳亢=气虚+阴虚>阳亢+痰湿>痰湿+瘀血>气虚+瘀血>阴虚+痰湿>气虚+痰湿=阴虚+瘀血=阳亢+瘀血,三证素组为气虚+阴虚+痰湿>气虚+阳亢+痰湿=气虚+痰湿+瘀血>阴虚+阳亢+痰湿=气虚+阴虚+瘀血。
2高血压病虚实性证素的血液流变学指标的比较结果为：在单证素组中,全血粘度、全血还原粘度(高切)、全血相对粘度、红细胞压积为实>虚(P<0.05)。在二证素组中：全血中切[50/S]：实>虚实夹杂(P<0.05)；全血低切[5/S]：实>虚(P<0.05),实>虚实夹杂(P<0.05)；全血低切[1/S]：实>虚(P<0.05)；全血还原粘度(低切)：实>虚(P<0.05)；红细胞聚集指数：实>虚(P<0.05)。结果大体可概括为实>虚实夹杂>虚。
3高血压病各证素(气虚、阴虚、阳亢、痰湿)血液流变学指标的比较结果为：全血粘度、全血还原粘度(高切)、全血高切相对粘度以及红细胞压积的结果大体为阳亢和痰湿的指标值大于阴虚和气虚(P<0.05),但阳亢和痰湿证素之间的血液流变学指标并无显著性差异(P>0.05),而阴虚和气虚之间的血液流变学指标也无显著性差异(P>0.05)。
4高血压病各证素及其相应组合血液流变学指标的比较结果为：虚性证素及其相应组合血液流变学指标的比较结果为：全血高切[200/S]：气虚+阴虚>气虚(P<0.05)；全血还原粘度(高切)：气虚+阴虚>气虚(P<0.05)；全血高切相对粘度：气虚+阴虚>气虚(P<0.05)；红细胞刚性指数：气虚+阴虚>气虚(P<0.05)。实性证素及其相应组合血液流变学指标的比较结果为：实性证素及其相应组合血液流变学指标无显著性差异(P>0.05)。虚性证素、实性证素及其相应组合血液流变学指标的比较结果为除了全血粘度：阳亢>阴虚、痰湿>阴虚、痰湿>气虚(P均<0.05)以及全血高切[200/S]气虚+痰湿>气虚(P<0.05)和全血高切相对粘度痰湿>气虚+痰湿(P<0.05)以外,虽然结果与上述总体研究所得结论实>虚实夹杂>虚一致,但经检验P均大于0.05,无明显差异。
5高血压病含瘀血证素与无瘀血证素患者血液流变学指标的比较无明显差异(P>0.05)。
结论：
1目前高血压病的病变多为两种证素相互作用导致,当然其在病变中所占的地位有主次分别,但也有单一证素者,两种以上证素常常出现于疾病后期并使疾病复杂化。高血压病主要为阴虚阳亢所致,病程中常出现痰湿瘀血等病理产物,后期常导致气阴两虚。对于疾病晚期以及病情复杂者常伴随痰湿或瘀血的产生。
2高血压病患者的血液流变学指标一般实>虚实夹杂>虚,实证患者正气不虚,血液流变学指标较高,虚证患者正气亏虚,血液流变学指标升高无实证患者明显。血粘度增加导致组织灌注减少,实证患者正气不虚增加血压以保持正常灌注的能力大,但对于血粘度增高的患者血压升高常进一步增加了血粘度,虚证患者正气亏虚而血粘度增加也较实证小。随着患者虚实证素的改变血液流变学指标常会随之出现变化。
3高血压病血液流变学指标升高明显多与阳亢和痰湿有关,气虚和阴虚患者血液流变学指标升高无阳亢和痰湿明显。
4高血压病不同证素相互作用组合后其血液流变学指标并不是单独证素血液流变学指标变化的简单相加。
5高血压病血液流变学指标升高不只出现于瘀血证中,也在一定程度上说明瘀血证是高血压病的潜在病因之一
6血粘度增高是高血压发病以及疾病进展的一个重要环节,常常随着血压、神经调节、血糖、血脂、电解质、激素等紊乱而出现相应变化,而通过本研究发现血粘度也常随着中医证素的改变而发生相应的变化。高血压病血粘度增高西医认为是系统器官组织神经体液调节失调所致,中医认为是脏腑气血阴阳失调所致,而它仅仅是病变的一个环节,针对血粘度进行治疗,在一定程度上可以治疗高血压并阻断其进展,还能防止其相关并发症的发生。
Objective:Observing hypertension patients' hemotheology indexes(whole blood viscosity of high[200/S]shear stress,whole blood viscosity of middle[50/S]shear stress and whole blood viscosity of low([5/S] and [1/S])shear stress,whole bloo d reduced viscosity of high shear stress,whole blood reduced viscosity of low s hear stress,whole blood relative viscosity of high shear stress,whole blood relati ve viscosity of low shear stress,plasma viscosity,hematocrit(HCT),erythrocyte sed imentation rate (ESR),K,red cell stiffness index,red cell conglomeration index,re d cell deformability index,fibrinogen(FIB))in order to find out the relationship b etween hemotheology indexes and syndrome elements(Qi deficiency,Yin deficien cy,Yang hyperactivity,phlegm and dampness,blood stasis) of hypertension patient s.
Methods:Collect 99 patients according with the Western medicine diagnosis st andard of hypertension Clinically and then separate them into different groups t hrough Bianzheng,and all the indexes of those mentioned above will be tested. Devide patients into single syndrome element group,two syndrome elements gro up,three syndrome elements group and four syndrome elements group by the n umber of their syndrome elements,then devide them into different groups by th eir syndrome element constitution.Classify them by the deficiency and excess s yndrome element of them,and by whether they have the blood stasis syndrome element or not.Finally compare the hemotheology indexes among the different groups,and study the distribution of syndrome element by the method of frequ ency distribution.Use t-test to compare sample mean between two qroups.All of the results will be checked up by statistics,then study the relationship between hemotheology indexes and TCM syndrome elements.
Results:
1 The comparison of population distribution of hypertension syndrome elements:r esults according to the quantity:two syndrome elements>single syndrome elemen t>three syndrome elements>four syndrome elements;results according to the typ es:the group of single syndrome element:Yang hyperactivity=phlegm and dampn ess>Yin deficiency>Qi deficiency>blood stasis,the group of two syndrome eleme nts:Yin deficiency+Yang hyperactivity=Qi deficiency+Yin deficiency>Yang hyper activity+phlegm and dampness>phlegm and dampness+blood stasis>Qi deficienc y+blood stasis>Yin deficiency+phlegm and dampness>Qi deficiency+phlegm and dampness=Yin deficiency+blood stasis=Yang hyperactivity+blood stasis,the grou p of three syndrome elements:Qi deficiency+Yin deficiency+phlegm and dampn ess>Qi deficiency+Yang hyperactivity+phlegm and dampness=Qi deficiency+phle gm and dampness+blood stasis>Yin deficiency+Yang hyperactivity+phlegm and dampness=Qi deficiency+Yin deficiency+blood stasis.
2The conclusion of comparison of the hemotheology indexes of deficiency and excess syndrome elements groups is:in the group of single syndrome element,t he result of those indexes(whole blood viscosity,whole blood reduced viscosity of high shear stress,whole blood relative viscosity and HCT) is:excess>deficien cy(P<0.05);in the group of two syndrome elements:whole blood viscosity of mi ddle[50/S]shear stress:excess>deficiency and excess(P<0.05),whole blood viscosit y of low[5/S] shear stress:excess>deficiency,excess>deficiency and excess(P<0.0 5),whole blood viscosity of low[1/S] shear stress:excess>deficiency,whole blood reduced viscosity of low shear stress:excess>deficiency(P<0.05),red cell conglom eration index:excess>deficiency(P<0.05).On the whole,the total result can be su mmarized to be excess>deficiency and excess>deficiency.
3The comparison result of the hemotheology indexes of syndrome elements(Qi deficiency,Yin deficiency,Yang hyperactivity,phlegm and dampness):the results of the whole blood viscosity,whole blood reduced viscosity of high shear stress,w hole blood relative viscosity of high shear stress and hematocrit(HCT) of Yang hyperactivity and phlegm and dampness are higher than those of Qi deficienc y and Yin deficiency(P<0.05),but there is no obvious difference between Yang hyperactivity and phlegm and dampness(P>0.05),so is Qi deficiency and Yin d-eficiency(P>0.05).
4The comparison results of the hemotheology indexes of hypertension syndrome element and the corresponding conbination:the results of the deficiency syndro me elements and the corresponding conbination:whole blood viscosity of high[2 00/S] shear stress:Qi deficiency+Yin deficiency>Qi deficiency(P<0.05),whole blo od reduced viscosity of high shear stress:Qi deficiency+Yin deficiency>Qi defic iency(P<0.05),whole blood relative viscosity of high shear stress:Qi deficiency+ Yin deficiency>Qi deficiency(P<0.05),red cell stiffness index:Qi deficiency+Yin deficiency>Qi deficiency(P<0.05).There is no obvious difference between the ex cess syndrome elements and the corresponding conbination(P>0.05).The results of the deficiency syndrome element,the excess syndrome element and the corre sponding conbination are:whole blood viscosity:Yang hyperactivity>Yin deficienc y,phlegm and dampness>Yin deficiency,phlegm and dampness>Qi deficiency(P<0. 05),and whole blood viscosity of high[200/S]shear stress:Qi deficiency+phlegm and dampness>Qi deficiency(P<0.05),whole blood relative viscosity of high shea r stress:phlegm and dampness>Qi deficiency+phlegm and dampness.Although th e rest of the results are according with the conclusion that excess>deficiency a nd excess>deficiency,P is higher than 0.05 by statistics.
5There is no obvious difference between hemotheology indexes of the hyperten sion patients who have the blood stasis syndrome element and those who don't have(P>0.05).
Conclusions:
lAt the present time hypertension results from the mutual effect of two syndro me elements. Of course,the roles they play in the lesion aren't the same,but ther e is also single syndrome element that leads to the disease.More than two path ological factors often come into existence at the later stage of the disease and make the disease more complicated.Hypertension often results from the action of Yin deficiency and Yang hyperactivity,and pathological products such as phl egm-dampness and blood stasis often come into existence in the progress of th e disease.Qi and Yin deficiency often come into existence at the end of the di sease.There are often hlegm-dampness and blood stasis for those people who ar e in the late stage of the disease and their disease is often more complicated.
2The level of the hemotheology indexes of the hypertension patients commonll y is excess>deficiency and excess>deficiency.The excess syndrome patients' vita 1 Qi isn't deficient,so their hemotheology indexes are higher.The deficiency syn drome patients'vital Qi is deficient,so their hemotheology indexes are not so h igh.That means the increase of blood viscosity leads to the decrease of tissue perfusion,because the excess syndrome patients' vital Qi isn't deficient,so they c an insease the blood pressure to preserve normal perfusion but also increase th e blood viscosity.The deficiency syndrome patients' vital Qi is deficient,so their blood viscosity is not increased as much as the excess syndrome.The excess a nd deficiency syndrome element often change with the hemotheology indexes.
3The rise of the hemotheology indexes of hypertension is often related to the Yang hyperactivity and phlegm and dampness,the hemotheology indexes of thos e people who belong to the Qi deficiency and Yin deficiency don't rise as hig h as those of Yang hyperactivity and phlegm and dampness.
4When different syndrome elements act upon one another,their hemotheology in dexes changes but not adding together simplly.
5The increase of the hemotheology indexes is not only exist in the blood stasi s syndrome.It also means blood stasis is one of the potential etiology of hyper tension.
6The increase of the blood viscosity is an important link in the happening and progress of hypertension.It changes following the disorder of the blood pressur e,neuroregulation,blood sugar,blood fat,electrolyte,hormone.According to this stud y,we know that blood viscosity also changes following the syndrome element. The increase of blood viscosity of hypertension is the maladjustment of system, tissue,organ,nerve and body fluid,also the maladjustment of ZangFu QiXue and YinYang.It is a link of the pathological change, so if we decrease the blood viscosity,not only can we treat and block up the progress of hypertension,but a lso prevent the happening of hypertension complication to a certain extent.
方法：临床收集符合高血压病西医诊断标准的99例患者进行辨证分组。根据患者含有证素数量的不同分别归入单证素组、二证素组、三证素组、四证素组,在各组内根据证素构成的不同再进行分组,根据证素的虚实属性将其归类,并根据是否含有瘀血证素进行分组。在各组间行血液流变学指标的比较,采用频数分布法进行中医证素分布研究,两组间比较用t检验,探讨各指标与高血压病中医证素间的关系。
结果：
1高血压病证素人群分布比较结果为：高血压病证素数量组合人群分布比较结果为：二证素>单证素>三证素>四证素；高血压病证素类型组合人群分布比较结果为：单证素组为阳亢=痰湿>阴虚>气虚>瘀血,二证素组为阴虚+阳亢=气虚+阴虚>阳亢+痰湿>痰湿+瘀血>气虚+瘀血>阴虚+痰湿>气虚+痰湿=阴虚+瘀血=阳亢+瘀血,三证素组为气虚+阴虚+痰湿>气虚+阳亢+痰湿=气虚+痰湿+瘀血>阴虚+阳亢+痰湿=气虚+阴虚+瘀血。
2高血压病虚实性证素的血液流变学指标的比较结果为：在单证素组中,全血粘度、全血还原粘度(高切)、全血相对粘度、红细胞压积为实>虚(P<0.05)。在二证素组中：全血中切[50/S]：实>虚实夹杂(P<0.05)；全血低切[5/S]：实>虚(P<0.05),实>虚实夹杂(P<0.05)；全血低切[1/S]：实>虚(P<0.05)；全血还原粘度(低切)：实>虚(P<0.05)；红细胞聚集指数：实>虚(P<0.05)。结果大体可概括为实>虚实夹杂>虚。
3高血压病各证素(气虚、阴虚、阳亢、痰湿)血液流变学指标的比较结果为：全血粘度、全血还原粘度(高切)、全血高切相对粘度以及红细胞压积的结果大体为阳亢和痰湿的指标值大于阴虚和气虚(P<0.05),但阳亢和痰湿证素之间的血液流变学指标并无显著性差异(P>0.05),而阴虚和气虚之间的血液流变学指标也无显著性差异(P>0.05)。
4高血压病各证素及其相应组合血液流变学指标的比较结果为：虚性证素及其相应组合血液流变学指标的比较结果为：全血高切[200/S]：气虚+阴虚>气虚(P<0.05)；全血还原粘度(高切)：气虚+阴虚>气虚(P<0.05)；全血高切相对粘度：气虚+阴虚>气虚(P<0.05)；红细胞刚性指数：气虚+阴虚>气虚(P<0.05)。实性证素及其相应组合血液流变学指标的比较结果为：实性证素及其相应组合血液流变学指标无显著性差异(P>0.05)。虚性证素、实性证素及其相应组合血液流变学指标的比较结果为除了全血粘度：阳亢>阴虚、痰湿>阴虚、痰湿>气虚(P均<0.05)以及全血高切[200/S]气虚+痰湿>气虚(P<0.05)和全血高切相对粘度痰湿>气虚+痰湿(P<0.05)以外,虽然结果与上述总体研究所得结论实>虚实夹杂>虚一致,但经检验P均大于0.05,无明显差异。
5高血压病含瘀血证素与无瘀血证素患者血液流变学指标的比较无明显差异(P>0.05)。
结论：
1目前高血压病的病变多为两种证素相互作用导致,当然其在病变中所占的地位有主次分别,但也有单一证素者,两种以上证素常常出现于疾病后期并使疾病复杂化。高血压病主要为阴虚阳亢所致,病程中常出现痰湿瘀血等病理产物,后期常导致气阴两虚。对于疾病晚期以及病情复杂者常伴随痰湿或瘀血的产生。
2高血压病患者的血液流变学指标一般实>虚实夹杂>虚,实证患者正气不虚,血液流变学指标较高,虚证患者正气亏虚,血液流变学指标升高无实证患者明显。血粘度增加导致组织灌注减少,实证患者正气不虚增加血压以保持正常灌注的能力大,但对于血粘度增高的患者血压升高常进一步增加了血粘度,虚证患者正气亏虚而血粘度增加也较实证小。随着患者虚实证素的改变血液流变学指标常会随之出现变化。
3高血压病血液流变学指标升高明显多与阳亢和痰湿有关,气虚和阴虚患者血液流变学指标升高无阳亢和痰湿明显。
4高血压病不同证素相互作用组合后其血液流变学指标并不是单独证素血液流变学指标变化的简单相加。
5高血压病血液流变学指标升高不只出现于瘀血证中,也在一定程度上说明瘀血证是高血压病的潜在病因之一
6血粘度增高是高血压发病以及疾病进展的一个重要环节,常常随着血压、神经调节、血糖、血脂、电解质、激素等紊乱而出现相应变化,而通过本研究发现血粘度也常随着中医证素的改变而发生相应的变化。高血压病血粘度增高西医认为是系统器官组织神经体液调节失调所致,中医认为是脏腑气血阴阳失调所致,而它仅仅是病变的一个环节,针对血粘度进行治疗,在一定程度上可以治疗高血压并阻断其进展,还能防止其相关并发症的发生。
Objective:Observing hypertension patients' hemotheology indexes(whole blood viscosity of high[200/S]shear stress,whole blood viscosity of middle[50/S]shear stress and whole blood viscosity of low([5/S] and [1/S])shear stress,whole bloo d reduced viscosity of high shear stress,whole blood reduced viscosity of low s hear stress,whole blood relative viscosity of high shear stress,whole blood relati ve viscosity of low shear stress,plasma viscosity,hematocrit(HCT),erythrocyte sed imentation rate (ESR),K,red cell stiffness index,red cell conglomeration index,re d cell deformability index,fibrinogen(FIB))in order to find out the relationship b etween hemotheology indexes and syndrome elements(Qi deficiency,Yin deficien cy,Yang hyperactivity,phlegm and dampness,blood stasis) of hypertension patient s.
Methods:Collect 99 patients according with the Western medicine diagnosis st andard of hypertension Clinically and then separate them into different groups t hrough Bianzheng,and all the indexes of those mentioned above will be tested. Devide patients into single syndrome element group,two syndrome elements gro up,three syndrome elements group and four syndrome elements group by the n umber of their syndrome elements,then devide them into different groups by th eir syndrome element constitution.Classify them by the deficiency and excess s yndrome element of them,and by whether they have the blood stasis syndrome element or not.Finally compare the hemotheology indexes among the different groups,and study the distribution of syndrome element by the method of frequ ency distribution.Use t-test to compare sample mean between two qroups.All of the results will be checked up by statistics,then study the relationship between hemotheology indexes and TCM syndrome elements.
Results:
1 The comparison of population distribution of hypertension syndrome elements:r esults according to the quantity:two syndrome elements>single syndrome elemen t>three syndrome elements>four syndrome elements;results according to the typ es:the group of single syndrome element:Yang hyperactivity=phlegm and dampn ess>Yin deficiency>Qi deficiency>blood stasis,the group of two syndrome eleme nts:Yin deficiency+Yang hyperactivity=Qi deficiency+Yin deficiency>Yang hyper activity+phlegm and dampness>phlegm and dampness+blood stasis>Qi deficienc y+blood stasis>Yin deficiency+phlegm and dampness>Qi deficiency+phlegm and dampness=Yin deficiency+blood stasis=Yang hyperactivity+blood stasis,the grou p of three syndrome elements:Qi deficiency+Yin deficiency+phlegm and dampn ess>Qi deficiency+Yang hyperactivity+phlegm and dampness=Qi deficiency+phle gm and dampness+blood stasis>Yin deficiency+Yang hyperactivity+phlegm and dampness=Qi deficiency+Yin deficiency+blood stasis.
2The conclusion of comparison of the hemotheology indexes of deficiency and excess syndrome elements groups is:in the group of single syndrome element,t he result of those indexes(whole blood viscosity,whole blood reduced viscosity of high shear stress,whole blood relative viscosity and HCT) is:excess>deficien cy(P<0.05);in the group of two syndrome elements:whole blood viscosity of mi ddle[50/S]shear stress:excess>deficiency and excess(P<0.05),whole blood viscosit y of low[5/S] shear stress:excess>deficiency,excess>deficiency and excess(P<0.0 5),whole blood viscosity of low[1/S] shear stress:excess>deficiency,whole blood reduced viscosity of low shear stress:excess>deficiency(P<0.05),red cell conglom eration index:excess>deficiency(P<0.05).On the whole,the total result can be su mmarized to be excess>deficiency and excess>deficiency.
3The comparison result of the hemotheology indexes of syndrome elements(Qi deficiency,Yin deficiency,Yang hyperactivity,phlegm and dampness):the results of the whole blood viscosity,whole blood reduced viscosity of high shear stress,w hole blood relative viscosity of high shear stress and hematocrit(HCT) of Yang hyperactivity and phlegm and dampness are higher than those of Qi deficienc y and Yin deficiency(P<0.05),but there is no obvious difference between Yang hyperactivity and phlegm and dampness(P>0.05),so is Qi deficiency and Yin d-eficiency(P>0.05).
4The comparison results of the hemotheology indexes of hypertension syndrome element and the corresponding conbination:the results of the deficiency syndro me elements and the corresponding conbination:whole blood viscosity of high[2 00/S] shear stress:Qi deficiency+Yin deficiency>Qi deficiency(P<0.05),whole blo od reduced viscosity of high shear stress:Qi deficiency+Yin deficiency>Qi defic iency(P<0.05),whole blood relative viscosity of high shear stress:Qi deficiency+ Yin deficiency>Qi deficiency(P<0.05),red cell stiffness index:Qi deficiency+Yin deficiency>Qi deficiency(P<0.05).There is no obvious difference between the ex cess syndrome elements and the corresponding conbination(P>0.05).The results of the deficiency syndrome element,the excess syndrome element and the corre sponding conbination are:whole blood viscosity:Yang hyperactivity>Yin deficienc y,phlegm and dampness>Yin deficiency,phlegm and dampness>Qi deficiency(P<0. 05),and whole blood viscosity of high[200/S]shear stress:Qi deficiency+phlegm and dampness>Qi deficiency(P<0.05),whole blood relative viscosity of high shea r stress:phlegm and dampness>Qi deficiency+phlegm and dampness.Although th e rest of the results are according with the conclusion that excess>deficiency a nd excess>deficiency,P is higher than 0.05 by statistics.
5There is no obvious difference between hemotheology indexes of the hyperten sion patients who have the blood stasis syndrome element and those who don't have(P>0.05).
Conclusions:
lAt the present time hypertension results from the mutual effect of two syndro me elements. Of course,the roles they play in the lesion aren't the same,but ther e is also single syndrome element that leads to the disease.More than two path ological factors often come into existence at the later stage of the disease and make the disease more complicated.Hypertension often results from the action of Yin deficiency and Yang hyperactivity,and pathological products such as phl egm-dampness and blood stasis often come into existence in the progress of th e disease.Qi and Yin deficiency often come into existence at the end of the di sease.There are often hlegm-dampness and blood stasis for those people who ar e in the late stage of the disease and their disease is often more complicated.
2The level of the hemotheology indexes of the hypertension patients commonll y is excess>deficiency and excess>deficiency.The excess syndrome patients' vita 1 Qi isn't deficient,so their hemotheology indexes are higher.The deficiency syn drome patients'vital Qi is deficient,so their hemotheology indexes are not so h igh.That means the increase of blood viscosity leads to the decrease of tissue perfusion,because the excess syndrome patients' vital Qi isn't deficient,so they c an insease the blood pressure to preserve normal perfusion but also increase th e blood viscosity.The deficiency syndrome patients' vital Qi is deficient,so their blood viscosity is not increased as much as the excess syndrome.The excess a nd deficiency syndrome element often change with the hemotheology indexes.
3The rise of the hemotheology indexes of hypertension is often related to the Yang hyperactivity and phlegm and dampness,the hemotheology indexes of thos e people who belong to the Qi deficiency and Yin deficiency don't rise as hig h as those of Yang hyperactivity and phlegm and dampness.
4When different syndrome elements act upon one another,their hemotheology in dexes changes but not adding together simplly.
5The increase of the hemotheology indexes is not only exist in the blood stasi s syndrome.It also means blood stasis is one of the potential etiology of hyper tension.
6The increase of the blood viscosity is an important link in the happening and progress of hypertension.It changes following the disorder of the blood pressur e,neuroregulation,blood sugar,blood fat,electrolyte,hormone.According to this stud y,we know that blood viscosity also changes following the syndrome element. The increase of blood viscosity of hypertension is the maladjustment of system, tissue,organ,nerve and body fluid,also the maladjustment of ZangFu QiXue and YinYang.It is a link of the pathological change, so if we decrease the blood viscosity,not only can we treat and block up the progress of hypertension,but a lso prevent the happening of hypertension complication to a certain extent.
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