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名老中医田从豁教授针灸治疗抑郁症经验总结
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摘要
本论文主要包括文献综述和经验总结两个部分。
     文献综述共三篇。第一篇“中医学对抑郁症的认识”回顾了古代及近、现代中医对抑郁症的认识及临床研究进展,从病名、病因病机、临床表现、辩证治则及临床经验等方面进行了论述。中医治疗抑郁症理论完善,为治疗抑郁症开辟了新的途径和方法。第二篇“针灸治疗抑郁症概况”论述了针灸临床治疗抑郁症的近况。针灸治疗抑郁症方法多样,操作简便,疗效确切。尤其对慢性患者,无西医治疗的副作用,故临床应用较为普遍。第三篇“现代医学对抑郁症研究进展”从抑郁症的发病因素、诊断及西药治疗三个方面,介绍了近年来现代医学对抑郁症的研究进展。
     正文部分总结了田从豁教授从形、从神、从脾胃论治抑郁症的经验特点,针灸治以通督调神、调理脾胃中焦、醒神开窍为原则,善用大椎齐刺以通调督脉、振奋阳气,百会、人中加电针以醒神开窍,调理脾胃中焦的升降气机以畅通腑气、宁心定志。特别针刺足太阳膀胱一侧线以治疗脏腑阴阳气血之形,足太阳膀胱二侧线以治疗五脏之神是田老治疗抑郁症的独特方法。田老师的方法,根据中医理论的辨证论治的基础下,临床上取得了较好的疗效。
The paper discusses in two parts:the reviews of the documents and the experience analysis.
     There are three review articles.The first one named"Chinese medicine theory for depression" is about the treatment for depression in Chinese medicine theory, including the name source,etiology,pathogenesis,differentiation,clinical treatment. The second one named "Acupuncture for depression" The second one named"Acupuncture for depression'is about the acupuncture treatment for depression. Acupuncture have many different ways to treat depression and have many dominances,including its easy way and good effects treat depression and have many ddominances,including its easy way and good effects without side-effect.So it's very popular in clinic.The third one named"Advance for depression in western medicine" is mainly about the etiology,diagnoses,treatment for depression in mainstream medicine.
     The experience part is focused on Professor Tian's special treatment for depression in acupuncture.He using Chinese Medicine theory differentiated it three parts of xing,shen,piweizhongshu to treat depression.Proffesor Tians' Needling Methods used like Triple puncture at Dazhui(GV14) for recurrent depression,electroacupuncture at Shuigou(GV26) and Baihui(GV20) are introduced. Especially based on Chinese medicine theory,he used the first bladder meridian line to treat "xing" the organ,and used the second bladder meridian line to treat the "shen" the mind.Professor Tian's Methods have great effects on clinical practice.
引文
[1]吕向阳、张向东.经方辨治卒中性抑郁症[J].国医论坛,1998,13(3):11
    [2]全世建.百合地黄汤加减治疗抑郁症30例临床观察[J].新中医,1999,31
    [3]金光亮.有关抑郁症季节型发病机理的研究及启示,北京中医药大学学报,1997,20(1):15-16
    [4]郭小青、田正良、米金辉,抑郁症中医病因病机分析[J].浙江中医杂志,2002,37(9):374-375
    [5]陈日宙.忧郁证从脾肾论治.光明中医杂志[J].1995,19(6):7-8
    [6]胡思荣.平心忘忧汤治疗抑郁症470例[J].湖北中医杂志,1996,18(2):4-5
    [7]赵英日.抑郁症发病时间的探析[J].实用中西医结合临床 2006,6(4):87-88
    [8]许沛虎.中医脑病学[M].北京:中国医药科技出版社,1998.925
    [9]张剑.李辅仁治疗老年抑郁症经验[J].中医杂志,2000,41(4):208
    [10]郝万山.柴桂温胆定志汤为主治疗精神抑郁症[J].北京中医药大学学报,1997,20(3):64
    [11]刘兰英、王玲玲.“脑为元神之府”理论在针灸治疗抑郁症中的指导意义[J].针灸临床杂志,2003,19(8):6-8
    [12]金世建.百合地黄汤加减治疗抑郁症30例疗效观察.新中医,1999,31(2):16-17
    [13]马欢.抑郁症病因病机研究探析[J].辽宁中医杂志,2005,32(6):537-538
    [14]赵燕.抑郁症中医证候及证候要素分布特点的文献研究[J].中医杂志,2006,9,49(9):691-693
    [15]彭计红、梅晓云.抑郁症的辨证分型概况[J].南京中医药大学学报,2004,20(1):62-64
    [16]胡随瑜、张宏耕、郑林等.1977例抑郁症患者中医不同证候构成比分析[J].中国医师杂志,2003,5(10):1312-1314
    [17]胡随瑜、张海男、唐凤英等.抑郁症肝郁气滞证证候标准第一轮专家问卷分析[J].中国中医基础医学杂志,2002,8(12):21-23
    [18]彭贵军、胡随瑜、张海男等.抑郁症肝郁脾虚、心脾两虚证证候标准第二 轮专家问卷分析[J].湖南中医学院学报,2003,23(5):37-39
    [19]樊晓平、彭展、杨胜跃等.基于多层前馈型人工神经网络的抑郁症分类系统研究[J].计算机工程与应用,2004,40(13):205-208
    [20]姬道绪、王天芳、薛晓琳.抑郁症常见证候精神症状表现特点的初步研究[J].北京中医药大学学报,2003,26(6):72-75
    [21]黄泳、龚伟、邹军、赵仓焕.头针治疗抑郁发作SCL-90评定结果分析[J].上海针灸杂志,2004(23):5-7
    [22]杜元灏、李桂平.调神疏肝针法治疗郁证的理论基础[J].中国针灸,2005,25(2),143-6
    [23]王玲玲、刘兰英.针灸治疗抑郁症临床思路[J].针灸临床杂志,2003,19(7),7-9
    [24]丁文娟、徐国祥.中医治疗抑郁症40例临床分析[J].江苏中医,1994,15(4):18
    [1]杨卓欣.针刺治疗抑郁症的临床疗效[J].针灸临床杂志.2003,19(8):28-29
    [2]申鹏飞、孔莉、石学敏.醒脑开窍法针刺治疗卒中后抑郁症临床研究[J].中国针灸,2005.25(1):11-13
    [3]刘飞虎.智能电针合并阿米替林治疗抑郁症临床观察[J].上海针灸杂志,2004,23(12):13-14
    [4]王寅、赵志府.针刺治疗脑卒中后抑郁失眠临床疗效[J].中国针灸,2004,24(9):603-606
    [5]李德平.复针治疗抑郁症44例[J].上海针灸杂志,2005,24(3):22
    [6]李世君等.解郁调神法针刺治疗郁证临床观察[J].中国中西医结合杂志2007,27(2):155-157
    [7]唐胜修、徐祖豪、唐萍.针刺治疗抑郁性神经症的临床研究[J].中国针灸,2003,23(10):585-586
    [8]张洪、何竟.电针治疗抑郁症的疗效观察[J].上海针灸杂志,2002,21(5):25-26
    [9]汤慧明、李航森等.电针联合小剂量阿米替林治疗抑郁症的疗效[J].中医药学报,2003,31(3):5-6
    [10]康波、张平根、雄生财等.电针与阿米替林治疗抑郁症对照观察[J].中国针灸,2002,22(6):383-384
    [11]王海箭.针刺治疗中风后抑郁症临床观察[J].中国针灸,2003,23(8):442-444
    [12]李晓泓、韩毳、张露芳等.艾灸大椎对慢性应激大鼠神经营养因子的影响[J].中医药学报,2002,30(6):51.
    [13]韩毳、李晓乱、郭顺根等.电针对抑郁大鼠中枢及外周单胺类神经递质的影响[J].中医药学刊,2004,22(1):185.
    [14]史榕荇、吴茜、秦丽娜等.电针百会、印堂对慢性应激模型大鼠体重及HPA 轴影响的研究[J].针灸临床杂志,2007,23(1):50-53.
    [15]吕梅、王玲玲.针刺治疗抑郁症选穴频次的分析.针灸临床杂志,2003,19(8):15.
    [16]罗和春.新电针疗法治疗抑郁症研究进展的启示.中国中西医结合杂志,2000,20(11):806-807.
    [17]任建宁.耳针治疗抑郁症50例.河南中医,2005,25(2):75.
    [18]李德平、王宝玲.腹针治疗抑郁症44例.上海针灸,2005,24(3):22.
    [19]黄泳、夏东斌.头电针治疗抑郁症30例临床观察.中西医结合学报,2004,2(2):151-160.
    [20]汪桂清、卫桂娜.针灸治疗抑郁症30例[J].针灸临床杂志,2006,22(7):29-30.
    [21]孙谊、高建忠.针刺治疗脑外伤后抑郁症临床观察[J].针灸临床杂志,2005,21(9):25.
    [22]吕建明、Thomas Neuerer、Ilko Atanasso.在德国针灸治抑郁症128例疗效观察[J].针灸临床杂志,2004,20(10):5-6.
    [23]魏晓萍、齐盛.醒神开四关治疗更年期抑郁38例[J].四川中医,2003,21(9):84.
    [24]刘素坤、赵秀敏、席志梅.卒中后抑郁发生率及针灸治疗[J].中国针灸,2006,26(7):472-473.
    [25]王振萍.针刺治疗抑郁症50例疗效观察[J].山西中医,2004,20(6):34.
    [26]杨丹红、冯利平.头针结合体针治疗妇女更年期忧郁症[J].浙江中医,1996,3:131.
    [27]高连印、刘晓艳.腹针调神理气健脾化痰法治疗抑郁症30例的临床观察[J]北京中医,2006,25(3):174-176.
    [28]尹秀茹.电针治疗抑郁症30例临床观察[J].河北中医,2005,27(7):527-528.
    [29]金光亮.电针对慢性应激抑郁模型大鼠脑内单胺类神经递质的影响[J].中华精神科杂志,1999,32(4):220.
    [30]韩毳、李学武.电针对慢性应激抑郁模型大鼠海马BDNF的影响[J].中国中医基础医学杂志,2001,7(7):535.
    [31]俞瑾、李晓燕.电针合用抗抑郁药能明显减少小鼠强迫游泳实验中的静止时间[J].针刺研究,2002,27(2):119-123.
    [32]张建斌、王玲玲、吕梅等.针刺不同腧穴对抑郁症模型大鼠行为学的影响[J].中国针灸,2005,25(9):639-643.
    [33]徐虹、孙忠人、李丽萍.针刺治疗抑郁症及其对患者下丘脑—垂体—肾上腺轴的影响[J].中国针灸,2004,24(2):7.
    [34]黄德宏、王成银、黄坚红,等百会穴针刺加灯盏花注射液穴位注射治疗脑梗死后抑郁症[J].中国临床康复,2004,8(28):6132-3
    [35]刘志顺.调理髓海法治疗中风后抑郁症30例临床观察[J].中国针灸,1997,17(4):200
    [36]庄子齐、王朝荣“智三针”配合点穴按摩治疗中风后抑郁症[J].中国针灸,2001,21(11):800-1
    [37]程坤、颜红、段可杰.针灸治疗抑郁症的临床与机理研究进展[J].中国针灸,2005,25(3):221-223.
    [38]李文迅、韩焱晶、陶娟等.电针对抑郁模型大鼠海马神经元凋亡的影响.中国中医药信息杂志,2005,12(2):33-35.
    [39]黄芳、曹铁、军曹锐、李宝岩等.电针内关、建里治疗抑郁症的临床研究.北京中医药大学学报,2008,15(2):25-17.
    [40]段冬梅、图娅.百优解与电针对轻、中度抑郁症的有效性评价.中国药物应用与监测,2008,5(1):11-14.
    [41]杨建立、刘晓华、甘雪晨等.电针及电针合并麦普替林治疗抑郁症临床疗效观察[J].健康心理学杂志,2000,8(1)92.
    [42]赵建玲.针药结合治疗抑郁症疗效观察[J].针灸临床杂志,2002,18(11):11.
    [43]许红.针药结合治疗抑郁症临床研究[J].上海针灸杂志,2003,22(6):7-8.
    [44]何宇峰、郭瑞兰、何逸均.腹针治疗女性更年期抑郁症疗效观察[J].上海针灸杂志,2008,27(4)
    [1]Schildkraut JJ.The catecholamine hypothesis of affective disorders:a review of supporting evidence.Am J Psychiatry.1965 Nov;122(5):509-22
    [2]Post RM、Gordon EK、Goodwin FK、BunneyWE Jr.;Central norepinephrine metabolism in affective illness:MHPG in the cerebrospinal fluid.Science.1973 Mar 9;179(77):1002-3.
    [3]Sulser F.Functional aspects of the norepinephrine receptor coupled adenylate cyclase system in the limbic forebrain and its modification by drugs which precipitate or alleviate depression:molecular approaches to an understanding of affective disorders.Pharmakopsychiatr Neuropsychopharmakol.1978 Jan;11(1):43-52.
    [4]Maas JW.Biogenic amines and depression.Biochemical and pharmacological separation of two types of depression.Arch Gen Psychiatry.1975 Nov;32(11):1357-61.
    [5]Castellani S、Ziegler MG、van Kammen DP、Alexander PE、Siris SG、Lake CR.Plasma norepinephrine and dopamine-beta-hydroxylase activity in schizophrenia.Arch Gen Psychiatry.1982 Oct;39(10):1145-9.
    [6]Roy A、Pickar D,Linnoila M,、Potter WZ.Plasma norepinephrine level in affective disorders.Relationship to melancholia.Arch Gen Psychiatry.1985 Dec;42(12):1181-5.
    [7]Esler M、Turbott J、Schwarz R、Leonard P、Bobik A、Skews H,Jackman G.The peripheral kinetics of norepinephrine in depressive illness.Arch Gen Psychiatry.1982 Mar;39(3):295-300.
    [8]Esler M、Leonard P、O'Dea K、Jackman G、Jennings G、Korner P.Biochemical quantification of sympathetic nervous activity in humans using radiotracer methodology:fallibility of plasma noradrenaline measurements.J Cardiovasc Pharmacol.1982;4 Suppl 1:S 152-7.
    [9]Friedman ML Stolk JM、Harris PQ、Cooper TB.Serum dopamine-beta-hydroxylase activity in depression and anxiety.Biol Psychiatry.1984 Apr;19(4):557-70.
    [10]Schildkraut J J.Neurochemical studies of the affective disorders:the pharmacological bridge.Am J Psychiatry.1970 Sep;127(3):358-60.
    [11]Segal DS、Kuczenski R、Mandell AJ.Theoretical implications of drug-induced adaptive regulation for a biogenic amine hypothesis of affective disorder.Biol Psychiatry.1974 Oct;9(2):147-59.
    [12]Svensson TH、Usdin T.Feedback inhibition of brain noradrenaline neurons by tricyclic antidepressants:alpha-receptor mediation.Science.1978 Dec 8;202(4372):1089-91.
    [13]COPPEN A、SHAW DM、MALLESON A.CHANGES IN 5-HYDROXYTRYPTOPHAN METABOLISM IN DEPRESSION.Br J Psychiatry.1965 Jan;111:105-7.
    [14]Curzon G、Green AR.Effects of immobilization on rat liver tryptophan pyrrolase and brain 5-hydroxytryptamine metabolism.Br J Pharmacol.1969 Nov;37(3):689-97.
    [15]Curzon G、Green AR.Rat liver tryptophan pyrrolase activity and brain 5-hydroxytryptamine.Biochem J.1969 Feb;111 (3):15P.
    [16]Maas JW.Biogenic amines and depression.Biochemical and pharmacological separation of two types of depression.Arch Gen Psychiatry.1975 Nov;32(11):1357-61
    [17]Asberg M、Tr(a|¨)skman L、Thor(?)n P.5-HIAA in the cerebrospinal fluid.A biochemical suicide predictor?;Arch Gen Psychiatry.1976.Oct;33(10):1193-7.
    [18]Cooper AM、Shamoian CA.Depression as seen by the psychiatrist.Dis Mon.1979Sep;25(12):1-64.
    [19]Ehsanullah RS.Uptake of 5-hydroxytryptamine and dopamine into platelets from depressed patients and normal subjects—influence of clomipramine,desmethylclomipramine and maprotiline.Postgrad Med J.1980;56 Suppl 1:31-5.
    [20]Scott M、Reading HW、Loudon JB.Studies on human blood platelets in affective disorder.Psychopharmacology (Berl).1979 Jan 31;60(2):131-5.
    [21]Wilson IC、Prange AJ Jr、Lara PP.Methyltestosterone with imipramine in men:conversion of depression to paranoid reaction.Am J Psychiatry.1974 Jan;131(1):21-4.No abstract available.
    [22]El-Yousef MK、Janowsky DS、Davis JM,Rosenblatt JE.Induction of severe depression by physostigmine in marihuana intoxicated individuals.Br J Addict Alcohol Other Drugs.1973 Dec;68(4):321-5.
    [23]Modestin J、Hunger J、Schwartz RB.Depressive effects of physostigmine.Arch Psychiatr Nervenkr.1973 Nov27;218(1):67-77.German.
    [24]Carroll BJ、Greden JFFeinbergM、James NM、Haskett RF、Steiner M、Tarika J.Neuroendocrine dysfunction in genetic subtypes of primary unipolar depression.Psychiatry Res.1980 Jul;2(3):251-8.
    [25]Whybrow PC,Prange AJ Jr.A hypothesis of hyroid-catecholamine-receptor interaction.Its relevance to affective illness.Arch Gen Psychiatry.1981 Jan;38(1):106-13.Review.
    [26]Extein I、Pottash AL、Gold MS、Silver JM.Thyroid-stimulating hormone response to thyrotropin-releasing hormone in unipolar depression before and after clinical improvement.Psychiatry Res.1982 Apr;6(2):161-9.
    [27]Loosen PT、Prange AJ Jr.Serum thyrotropin response to thyrotropin-releasing hormone in psychiatric patients:a review.Am J Psychiatry.1982 Apr;139(4):405-16.
    [28]Bremner JDNarayan M、Anderson ER、Staib LH、Miller HL、Charney DS.Hippocampal volume reduction in major depression.Am J Psychiatry.2000 Jan;157(1):115-8.
    [29]Maes M.Introduction to the special section.Int J Neuropsychopharmacol.2002 Dec;5(4):329-31.Review.
    [30]Leonhard K,Korff I、Schultz H.Temperament in families with monopolar and bipolar phasic psychoses.Psychiatr Neurol (Basel).1962;143:416-34.German.No abstract available.
    [31]Callahan AM、Frye MA、Marangell LB、George MS、Ketter TA,L'Herrou T、Post RM.Comparative antidepressant effects of intravenous and intrathecal thyrotropin-releasing hormone:confounding effects of tolerance and implications for therapeutics.Biol Psychiatry.1997 Feb 1;41(3):264-72.
    [32]Musselman DL、Nemeroff CB.Depression and endocrine disorders:focus on the thyroid and adrenal system,Br J Psychiatry Suppl.1996 Jun;(30):123-8
    [33]Stübner S、Sch(o|¨)nT、Padberg F、Teipel SJ、Schwarz MJ、Haslinger A、Buch K、Dukoff R、Lasser R、Müller N、Sunderland T、Rapoport SI、M(o|¨)ller HJ、Hampel H.Interleukin-6 and the soluble IL-6 receptor are decreased in cerebrospinal fluid of geriatric patients with major depression:no alteration of soluble gp130.Neurosci Lett.1999 Jan 15;259(3):145-8.
    [34]Jacoby R、Levy R.CT scanning and the investigation of dementia:a review.J R Soc Med.1980 May;73(5):366-9.
    [35]Late-onset depression with white matter lesions.Lesser IM、Hill-Gutierrez E、Miller BL、Boone KB.Psychosomatics.1993 Jul-Aug;34(4):364-7.
    [36]Krishnan KR、Doraiswamy PM、Lurie SN、Figiel GS、Husain MM、Boyko OB、Ellinwood EH Jr、Nemeroff CB.Pituitary size in depression.J Clin Endocrinol Metab.1991 Feb;72(2):256-9.
    [37]Baxter LR Jr.Positron emission tomography studies of cerebral glucose metabolism in obsessive compulsive disorder.J Clin Psychiatry.1994 Oct;55 Suppl:54-9.Review.
    [38]Duman RS、Monteggia LM.A neurotrophic model for stress-related mood disorders.Biol Psychiatry.2006 Jun 15;59(12):1116-27.Epub 2006 Apr 21.
    [39]Sairanen M、Lucas G、Ernfors P、Castr(?)n M、Castr(?)n E.Brain-derived neurotrophic factor and antidepressant drugs have different but coordinated effects on neuronal turnover,proliferation,and survival in the adult dentate gyrus.J Neurosci.2005 Feb 2;25(5):1089-94
    [40]IsingM、HorstmannS、Kloiber S、Lucae S、Binder EB、KernN、Künzel HE、Pfennig A、Uhr M、Holsboer F.Combined dexamethasone/corticotropin releasing hormone test predicts treatment response in major depression-a potential biomarker.Biol Psychiatry.2007 Jul 1;62(1):47-54.Epub 2006 Nov 21.
    [41]Barden N、Reul JM、Holsboer F.Do antidepressants stabilize mood through actions on the hypothalamic-pituitary-adrenocortical system.Trends Neurosci.1995 Jan;18(1):6-11.Review.
    [42]Briley M.Specific serotonin and noradrenaline reuptake inhibitors(SNRIs).A review of their pharmacology,clinical efficacy and tolerability.Human Psychopharmacology:Clinical andExperimental.13,99-111
    [43]Nemeroff CB.The corticotropin-releasing factor (CRF) hypothesis of depression:new findings and new directions.Mol Psychiatry.1996 Sep;1(4):336-42.Review.No abstract available.
    [44]Lesch KIN Bengel D、Heils A、Sabol SZ、Greenberg BD,Petri S,Benjamin J、Müller CR、Hamer DH、Murphy DL.Association of anxiety-related traits with a polymorphism in the serotonin transporter gene regulatory region.Science.1996 Nov 29;274(5292):1527-31.
    [45]Caspi A、Sugden K、Moffitt TE、Taylor A、Craig IW、Harrington H、McClay J、Mill J、Martin J、Braithwaite A、Poulton R.Influence of life stress on depression:moderation by a polymorphism in the 5-HTT gene.Science.2003 Jul 18;301(5631):386-9.
    [46]Arinami T,Li L、Mitsushio H、Itokawa M,Hamaguchi H、Toru M.An insertion/deletion polymorphism in the angiotensin converting enzyme gene is associated with both brain substance P contents and affective disorders.Biol Psychiatry.1996 Dec 1;40(11):1122-7.
    [47]Baghai TC、Binder EB、Schule C、Salyakina D、Eser D、Lucae S、Zwanzger P、Haberger C、Zill P、Ising M、Deiml T、Uhr M、Illig T、Wichmann HE、 Modell S、Nothdurfter C、Holsboer F、Müller-Myhsok B,M(o|¨)ller HJ、Rupprecht R、Bondy B.Polymorphisms in the angiotensin-converting enzyme gene are associated with unipolar depression,ACE activity and hypercortisolism.Mol Psychiatry.2006 Nov;11(11):1003-15.Epub 2006 Aug 22.
    [48]Baghai TC、Schule C、Zwanzger P、Minov C、Zill P、Ella R、Eser D、Oezer S、Bondy B、Rupprecht R.Hypothalamic-pituitary-adrenocortical axis dysregulation in patients with major depression is influenced by the insertion/deletion polymorphism in the angiotensin Ⅰ-converting enzyme gene.Neurosci Lett.2002 Aug 16;328(3):299-303.
    [49]Bondy B、Baghai TC、Zill P、Schule C、Eser D、Deiml T、Zwanzger P、Ella R、Rupprecht R.Genetic variants in the angiotensin Ⅰ-converting-enzyme(ACE)and angiotensin Ⅱ receptor(AT1) gene and clinical outcome in depression.Prog Neuropsychopharmacol Biol Psychiatry.2005 Jul;29(6):1094-9.
    [50]Gallagher P,Young AH.Mifepristone treatment for depression and psychosis:a review of the therapeutic implications.Neruopsychiatric Disease and Treatment.
    [51]唐济生.吗氯贝胺治疗抑郁症双盲对照研究.中国神经精神疾病杂志,2001,27(1):69-70
    [52]Breen R、McCormac RJ 4th.A fresh look at management of depression.How to choose and use the newer antidepressant drugs.Postgrad Med.2002Sep;112(3):28-30,33-4,37-40
    [53]Wong EH、Sonders MS、Amara SG、Tinholt PM、Piercey MF、Hoffmann WP、Hyslop DK、Franklin S、Porsolt RD、Bonsignori A、Carfagna N、McArthur RA.Reboxetine:a pharmacologically potent,selective,and specific norepinephrine reuptake inhibitor.Biol Psychiatry.2000 May 1;47(9):818-29.
    [54]Benkert O、Muller M、Szegedi A.An overview of the clinical efficacy of mirtazapine.Hum Psychopharmacol.2002 Jun;17 Suppl 1:S23-6.
    [55]顾牛范、李华芳、舒良等.文拉法新缓解剂治疗抑郁症的双盲、随机、平行对照、多中心临床研究.中国新药与临床杂志,2002,21(2):661.
    [56]Manji HK、Quiroz JA、Sporn J、Payne JL、Denicoff K、A Gray N、Zarate CA Jr、Charney DS.Enhancing neuronal plasticity and cellular resilience to develop novel,improved therapeutics for difficult-to-treat depression.1:Biol Psychiatry.2003 Apr 15;53(8):707-42.

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