用户名: 密码: 验证码:
不同室内热经历下人体生理热适应对热反应的影响研究
详细信息    本馆镜像全文|  推荐本文 |  |   获取CNKI官网全文
摘要
热适应研究是人体热舒适研究的重要领域,对于人们正确认识气候、建筑环境对热舒适影响规律具有重要意义,也能为今后建筑设计标准制定和节能设计提供指导。但已有的研究缺少对热适应内在机制的深入探索,尤其在生理适应和热舒适之间的关系上还不够明确;此外,现有的热适应模型将室内舒适温度完全归结为室外气候的影响,忽略了人的室内热经历的重要作用,其合理性和可靠性还需要进一步的研究。
     针对以上问题,本文开展了以下的研究工作:
     (1)进行了表征人体热反应的代表性生理指标的实验研究。通过人体热反应实验,对已有文献中提到较多的可能可以用来反映人体热反应的生理指标进行验证,并对一些新的生理指标进行探索,最终筛选出皮肤温度和心率变异性可以作为表征人体热反应的代表性指标。
     (2)对具有不同夏季室内热经历的人群进行人体热反应的实验研究。该研究比较了长期在空调建筑中的人(空调组)与长期在非空调建筑中的人(非空调组)在相同热冲击环境下的主观热反应、生理反应的差异。结果表明,夏季室内热经历对人体在偏热环境下的热适应性有重要的影响作用,空调组对偏热环境的生理适应性不如非空调组,并且发现对偏热环境的生理适应性能够显著改善人体在偏热环境下的热舒适,但不影响人体在中性环境下的热舒适。
     (3)对具有不同冬季室内热经历的人群进行人体热反应的实验研究。该研究比较了冬季长期在采暖建筑中的人(采暖组)与长期在非采暖建筑中的人(非采暖组)在相同偏冷环境下的主观热反应、生理反应的差异。结果表明,冬季室内热经历对人体在偏冷环境下的热适应性有重要的作用,采暖组对偏冷环境的生理适应性不如非采暖组,并且发现对偏冷环境的生理适应性能够显著改善人们在偏冷环境下的热舒适。
     (4)以实验研究为基础,结合生理学、心理学的相关理论进行了人体生理适应与热适应、热经历与热适应性的关系的分析。分析结果明确了生理适应是热适应的本质属性,提出了皮肤温度、出汗率、HRV和HSP70可以作为人体对偏热环境产生生理适应的表征指标,皮肤温度可以作为人体对偏冷环境产生生理适应的表征指标;指出了热经历是影响人体热适应性的重要因素,对多数人而言,室内热经历比室外热经历的影响更显著;对热经历、热适应内在机制、热舒适之间建立了较完善的热适应模型作用框架。
     本课题研究所积累的人体热反应实验数据和研究分析,能够为热适应模型的合理建立提供数据支持和理论依据;本文所证实的室内热经历对生理适应的重要影响以及生理适应在建筑环境人体热适应中的重要作用,为进一步完善建筑环境控制标准设定提供理论指导。
Thermal adaption is an important field of studies on human thermal comfort, as it plays a significant role on helping to understand the effects of the outdoor climate and built environments on human thermal comfort, thus provides guidance for the design of environmental control standards and building energy savings. However, current studies on thermal adaption do not explain clearly such internal mechanisms of thermal adaptation as the relation between physiological acclimatization and thermal comfort. Besides, the current Adaptive Models only link indoor comfort temperatures to outdoor climate and do not consider the effects of building occupants'past indoor thermal histories on thermal comfort, which raises a doubt on its reliability and rationality. The objectives of this paper are to exam the effects of physiological acclimatization on thermal comfort and the effects of past indoor thermal histories on thermal adaption.
     Research results presented in this paper are as follows:
     (1) Human thermal response experiments were conducted in a climate chamber to determine if some of the physiological parameters used in existing studies to reflect thermal comfort were sensitive to thermal responses. Some other new physiological parameters were also investigated. Results indicated that skin temperature and heart rate variability (HRV) present close relationships with thermal comfort and could be used in further studies on human thermal response.
     (2) Climate chamber experiments were conducted on the influence of people's past indoor thermal histories in summer on human thermal response:we tracked the different responses of thermal comfort and physiological indexes to a heat shock of people accustomed to buildings air-conditioned or not in summertime conditions. Results showed that living and working in indoor thermal environments for long periods of time in summer affects people's physiological acclimatization to hot environments-people accustomed to air-conditioned environments have a weaker environments-people accustomed to air-conditioned environments have a weaker capacity to acclimatize to hot environments than those accustomed to non-air-conditioned environments-and that physiological acclimatization to hot environments can significantly affect thermal comfort response to hot environments, but does not affect thermal comfort response to neutral environments.
     (3) Climate chamber experiments on the influence of people's past indoor thermal histories in winter on human thermal response were conducted:we examined the different responses of thermal comfort and physiological indexes to cold environments between the people accustomed to buildings heated or not in winter. It showed that living and working in indoor thermal environments for long periods of time in winter affects people's thermal adaption to cold environments-people accustomed to heated environments have a weaker capacity to acclimatize to cold environments than those accustomed to non-heated environments - and that physiological acclimatization to cold environments can significantly affect people's thermal comfort response to cold environments.
     (4) Combining the experimental results above with related theories in the fields of physiology and psychology, the role of physiological acclimatization on thermal adaption, the effects of thermal histories on thermal adaptability were analyzed. It pointed out the fact that physiological acclimatization is an essential factor of thermal adaption, that skin temperature, sweating rate, HRV and HSP70 levels can be used as representative indexes for human thermal adaptability to hot environments and that skin temperature for human thermal adaptability to cold environments. Besides, it revealed that thermal histories are extremely important factors on thermal adaptability: for most people, indoor thermal histories have a more significant influence on human thermal adaptability than outdoor thermal histories. In addition, we proposed a model for the internal relationship between thermal history, the internal mechanisms of thermal adaption and human thermal comfort, in order to improve the conceptual framework of the Adaptive Model.
     In this paper, experimental data on human thermal response was reported that led to some improvement proposals for the conceptual framework of the adaptive model, they could contribute to a more rational establishment of the adaptive model based on actual experimental data; besides, the important impacts of past indoor thermal histories of building occupants on physiological acclimatization and the significant role played by physiological acclimatization on thermal adaption in built environments were put into light, which could provide theoretical guidance for the design of new building environmental control standards.
引文
[1]Fanger P O. Thermal comfort. Malabar F L:Rober t E Krieger Publishing Company,1982
    [2]ASHRAE. ASHRAE Standard 55a-1995 Thermal environmental conditions for human occupancy. Atlanta: ASHRAE,1995.
    [3]International Standards Organization. ISO Standard 7730-2005 Moderate thermal environments-determination of the PMV and PPD indices and specification of the conditions for thermal comfort[S]. Switzerland: International Standards Organization,2005.
    [4]戴自祝.室内空气质量与通风空调.中国卫生工程学,2002,1(1):54-56
    [5]清华大学建筑节能研究中心.中国建筑节能年度发展研究报告.北京:中国建筑工业出版社,2011.
    [6]M.A. Humphreys. Field studies of thermal comfort compared and applied. J Inst Heat & Vent Eng,1976,44(1):5-27.
    [7]G.S. Brager, R.J. de Dear. Thermal adaptation in the built environment:A literature review. Energy and Buildings,1998,27(1):83-96.
    [8]ASHRAE. ASHRAE Standard 55a-2004. Thermal environmental conditions for human occupancy. Atlanta:ASHRAE,2004.
    [9]金招芬,朱颖心.建筑环境学.北京:中国建筑工业出版社,2003.
    [10]Ealiwa M A, Taki A H, Howarth A T, et al. An investigation into thermal comfort in the summer season of Ghadames, Libya. Building and Environment,2001,36(2):231-237.
    [11]de Dear R J, Brager G S. Developing an adaptive model of thermal comfort and preference. ASHRAE Trans,1998,104(1):145-167.
    [12]Fanger P O, Toftum J. Thermal Comfort in the future-Excellence and Expectation.//The International conference Moving Thermal Standards into the 21 st Century, Windsor,2001:11-18.
    [13]纪秀玲,戴自祝,甘永祥.夏季室内人体热感觉调查.中国卫生工程学,2003,2(3):141-143.
    [14]纪秀玲,王保国,刘淑艳,等.江浙地区非空调环境热舒适研究.北京理工大学学报,2004,24(12):1100-1103.
    [15]江燕涛,杨昌智,李文菁,等.非空调环境下性别与热舒适的关系.暖通空调,2006,36(5):17-21.
    [16]陈慧梅,张宇峰,王进勇等.我国湿热地区自然通风建筑夏季热舒适研究—以广州为例.暖通空调,2010,40(2):96-101.
    [17]ASHRAE. ASHRAE Standard 55-1981 Thermal Environmental Conditions for Human Occupancy. Atlanta: ASHRAE,1981.
    [18]ASHRAE. ASHRAE Standard 55-1992 Thermal environmental conditions for human occupancy. Atlanta:ASHRAE,1992.
    [19]ISO. International Standard 7730-1994 Moderate thermal environments-determination of the PMV and PPD indices and specification of the conditions of thermal comfort. Geneva:ISO,1994.
    [20]Cena K M. Thermal and non-thermal aspects of comfort surveys in homes and offices, in:N.A. Oseland. M.A. Humpheys (Eds.). Thermal comfort:Past, Presence and Future,1994.
    [21]Humpreys M A, Nicol J F. The validity of ISO-PMV for predicting comfort votes in everyday thermal environments. Energy and Buildings,2002 (34):667-684
    [22]Humphreys M A. Outdoor temperatures and comfort indoors. Building Research and Practice,1978,6(2):92-105
    [23]Fanger P O., Toftum J. Extension of the PMV model to non-air-conditioned buildings in warm climates, Energy and Buildings,2002,34(6):533-536
    [24]周翔.动态热环境下人体热反应机理研究—气流湍流度的影响[硕士学位论文].北京:清华大学,2005.
    [25]欧阳沁.建筑环境中气流动态特征与影响因素研究[博士学位论文].北京:清华大学,2005.
    [26]欧阳沁,戴威,朱颖心.建筑环境中自然风与机械风的谱特征分析.清华大学学报(自然科学版),2005,45(12):1585-1588.
    [27]Humphreys M A, Nicol J F. Understanding the adaptive approach to thermal comfort, ASHRAE Trans,1998,104(1):991-1004.
    [28]张宇峰,赵荣义.建筑环境人体热适应研究综述与讨论.暖通空调,2010,40(9):38-48.
    [29]Rudloff W. World climates. Stutgart: Wissenschaftliche Verlagsgesell schaft, 1981.
    [30]Humphreys M A, Nicol J F. Outdoor temperature and indoor thermal comfort: raising the precision of the relationship for the 1998 ASHRAE database of field studies.ASHRAE Trans,2000,106(2):485-492.
    [31]de Dear R J, Brager G S. Thermal comfort in naturally ventilated buildings: revisions to ASHRAE Standard 55. Energy and Buildings,2002,34:549-561.
    [32]杨柳.建筑气候分析与设计策略研究[博士学位论文].西安:西安建筑科技大学,2003.
    [33]茅艳.人体热舒适气候适应性研究[博士学位论文].西安:西安建筑科技大学,2006.
    [34]杨薇,张国强.湖南某大学校园建筑环境热舒适调查研究.暖通空调,2006,36(9):95-101.
    [35]李俊鸽.夏热冬冷地区人体热舒适气候适应模型研究[硕士学位论文].西安:西安建筑科技大学,2006.
    [36]叶晓江.人体热舒适机理及应用研究[博士学位论文].上海:上海交通大学,2005.
    [37]杨薇.夏热冬冷地区住宅夏季热舒适状况以及适应性研究.湖南:长沙大学,2007.
    [38]刘晶.夏热冬冷地区自然通风建筑室内热环境与人体热舒适的研究.重庆:重庆大学,2007.
    [39]曹彬,朱颖心,欧阳沁,等.北京地区冬季室内人体热舒适性及热适应性调查.暖通空调,2010,40(5):35,98-101.
    [40]周翔.偏热环境下人体热感觉影响因素及评价指标研究[博士学位论文].北京:清华大学,2008.
    [41]陈慧梅.湿热地区混合通风建筑环境人体热适应研究[硕士学位论文].广州:华南理工大学,2010.
    [42]Fishman D S., Pimbert S L. The thermal environment in offices. Energy and Buildings.1982,5(2):109-112.
    [43]de Dear R J, Leow K G, Foo S C. Thermal comfort in the humid tropics-field experiments in air-conditioned and naturally ventilated buildings in Singapore. International Journal of Biometeorology.1991,34(4):259-265.
    [44]Busch J F. Tale of two populations:thermal comfort in air-conditioned and naturally ventilated offices in Thailand. Energy and Buildings 1992,18(3-4): 235-249.
    [45]Yamtraipat N, Khedari J, Hirunlabh J. Thermal comfort standards for air conditioned buildings in hot and humid Thailand considering additional factors of acclimatization and education level. Solar Energy.2005,78(4): 504-517.
    [46]胡钦华,丁秀娟,李奎山.关于热感觉和热舒适与热适应性的讨论.山西建筑,2007,33(29):1-2.
    [47]徐涛,刘刚,康侍民.动态热环境下热舒适的实验研究.建筑热能通风空调,2010,29(2):62-66.
    [48]郑明仁,黄瑞隆.热湿地区空调型住家环境的热舒适要求.同济大学学报(自然科学版),2008,36(6):817-822.
    [49]Baker N, Standeven M. Thermal comfort for free-running buildings. Energy and Buildings,1996,23(3):175-182.
    [50]Baker N, Standeven M. Comfort criteria for passively cooled buildings a pascool task. Renewable Energy,1994,5(5-8):977-984.
    [51]Heidari S, Sharples S. A comparative analysis of short term and long term thermal comfort surveys in Iran.//Moving Thermal Comfort Standards into the 21st Century, Windsor 2001:223-234.
    [52]夏一哉.气流脉动强度与频率对人体热感觉的影响研究[博士学位论文].北京:清华大学,2000.
    [53]Nikolopoulou M, Steemers K. Thermal comfort and psychological adaptation as a guide for designing urban spaces. Energy and Building,2003,35(1): 95-101.
    [54]Hensel H. Thermoreception and Temperature Regulation. London:Academic Press,1981
    [55]上海第一医学院.人体生理学.北京:人民卫生出版社,1976.
    [56]McIntyre D A. Indoor climate. London:Applied Science Publishers Ltd, 1980.
    [57]Bulcao C F, Frank S M, Raja S N, et al. Relative contribution of core and skin temperatures to thermal comfort in humans. Journal of Thermal Biology, 2000,25(1-2):147-150.
    [58]Danni Wang, Hui Zhang, Edwards Arens, et al. Observations of upper-extremity skin temperature and corresponding overall-body thermal sensations and comfort. Building and Environment,2007,42(12):3933-3943.
    [59]Charlie Huizenga, Hui Zhang, Edward Arens, et al. Skin and core temperature response to partial-and whole-body heating and cooling. Journal of Thermal Biology,2004,29(7-8):549-558.
    [60]Kazuyo Tsuzuki, Yutaka Tochihara, Tadakatsu Ohnaka, et al. The effects of wind and thermal radiation on thermal response during rest and exercise in a cold environment. Journal of Thermal Biology,1993,18, (5-6):633-637.
    [61]Tomonori Sakoi, Kazuyo Tsuzuki, Shinsuke Kato, et al. Thermal comfort, skin temperature distribution, and sensible heat loss distribution in the sitting posture in various asymmetric radiant fields. Building and Environment,2007, 42(12):3984-3999.
    [62]Nakamura M T, Yoda T, Crawshaw L I, et al. Regional differences in temperature sensation and thermal comfort in humans. Journal of Applied Physiology,2008,105(6):1897-1906.
    [63]徐小林.重庆夏季室内热环境对人体生理指标及热舒适的影响研究[硕士学位论文].重庆:重庆大学,2005.
    [64]吴婧.室内空气流速与人体舒适及生理应激关系研究[硕士学位论文].重庆:重庆大学,2005.
    [65]罗明智.室内空气流速对人体生理指标及热舒适性的影响研究[硕士学位论文].重庆:重庆大学,2005.
    [66]叶晓江.人体热舒适机理及应用研究[博士学位论文].上海:上海交通大学,2005.
    [67]Yao Ye, Lian Zhiwei, Liu Weiwei, et al. Experimental study on physiological responses and thermal comfort under various ambient temperatures. Physiology & Behavior,2008,93(1/2):310-321.
    [68]Liu Weiwei, Lian Zhiwei, Liu Yuanmou. Heart rate variability at different thermal comfort levels. European Journal of Applied Physiology,2008, 103(3):361-366.
    [69]Joo-Young Lee, MohamedSaat, ChinmeiChou, etc. Cutaneous Warm and Cool Sensation Thresholds and the Inter-threshold Zone in Malaysian and Japanese Males. Journal of Thermal Biology,2010,35(2):70-76.
    [70]张明海,杨明杰,吴心魁,等.人体热适应评价指标和标准的研究.广后医学增刊,1994:44-46.
    [71]Getting M J, Sambrook J. Protein folding in the cell. Nature,1992,355(6355): 33-45.
    [72]张国高,贺涵贞,吴扬,等.职业卫生中热休克蛋白的研究.基础医学与临床,1995,15(2):7-10.
    [73]Li G C, Petersen N S, Mitchell H K. Induced thermal tolerance and heat-shock protein-synthesis in Chinese-hamster ovary cells. International journal of radiation oncology biology physics.1982,8(1):63-67.
    [74]Barbara J W, Kingston R E, Morimoto R I. Human HSP70 promoter contains at least two distinct regulatory domains. The Proceedings of the National Academy of Sciences,1986,83(3):629-633.
    [75]王自正,茅志成,王长来,等.高温中暑病人血浆中热应激蛋白(HSP70)及其抗体水平的观察研究.中国急救医学,1999,19(8):465-467.
    [76]Gagge A P, Stolwijk J A J, Hardy J D. Comfort and thermal sensations and associate physiological responses at various ambient temperatures. Environment Research,1967,1(1):1-20.
    [77]余娟,朱颖心,欧阳沁等.关于生理指标在人体热舒适,工作效率和长期健康评价的研究技术路线探讨.暖通空调,2010,40(3):1-5.
    [78]马瑞山.航空航天生理学.西安:陕西科学技术出版社,1999.
    [79]郭继红,张萍.动态心电图学.北京:人民卫生出版社,2003.
    [80]张建福,彭聿平,闫长栋.人体生理学.北京:高等教育出版社,2007.
    [81]李颖洁,邱意弘,朱贻盛.脑电信号分析方法及其应用.北京:科学出版社,2009.
    [82]中国疾病预防控制中心环境与健康相关产品安全所.国家自然基金重点项目-住宅微气候环境中热物理问题子课题“夏季空调环境热物理因素的人群健康影响”研究报告.2003.
    [83]Myers G, Workman M, Birkett C, et al. Problems in measuring heart rate variability of patients with congestive heart failure. Journal of Electrocardiology,1992,25 (S1):214-219.
    [84]Akselrod S, Gordon D, Ubel F A, et al. Power spectrum analysis of heart rate fluctuation:a quantitative probe of beat to beat cardiovascular control, Science,1981,213:220-222.
    [85]Kleiger R E, Miller J P, Bigger J T, et al. Decreased heart rate variability and its association with increased mortality after acute myocardial infarction. American Journal of Cardiology,1987,59(4):256-262.
    [86]Malik M, Farrell T, Cripps T, et al. Heart rate variability in relation to prognosis after myocardial infarction:selection of optimal processing techniques. European Heart Journal,1989,10(12):1060-1074.
    [87]Hotchkiss R, Nunnally I, Lindquist S, et al. Hyperthermia protects mice against the lethal effects of endotoxin. American journal of physiology,1993, 265(6):1447-1457.
    [88]邬堂春,贺涵贞,张国高.热应激蛋白研究的进展与前景.中华预防医学杂志,2000,34(1):6-7.
    [89]李裕和.热应激蛋白70在热适应中的作用.中国运动医学杂志,2000,19(2):182-183
    [90]张文彤,闫洁主编.SPSS统计分析基础教程.北京:高等教育出版社,2004.
    [91]Hamada S, Torii M, Szygula Z, et al. Effect of partial body cooling on thermophysiological responses during cycling work in hot environment. Journal of Thermal Biology,2006,31(1-2):194-207.
    [92]Shinde U, Inouye M. Intramolecular chaperones and protein folding. Trends in biochemical sciences,1993,18(11):442-446.
    [93]Li G C, Li L G, Liu Y K, et al. Thermal response of rat fibroblasts stably transfected with the human 70-kda heat-shock protein-encoding gene. Proceedings of the National Academy of Sciences of the United States of America,1991,88(5):1681-1685.
    [94]Kiang J G, Tsokos G C,. Heat Shock Protein 70 kDa: Molecular Biology, Biochemistry, and Physiology. Pharmacology & Therapeutics,1998,80 (2): 183-201
    [95]虞学军.航天高温应急的人体生理反应[博士学位论文].西安:第四军医大学.2000.
    [96]Klemenz R, Haultmark D, Gehring W J. Selective translation of heat shock mRNA in Drosophila melanogaster depends on sequence information in the leader. EMBO Journal,1985,4(8):2053-2060.
    [97]Parsell D A, Lindpuist S. The Function of Heat-Shock Proteins in Stress Tolerance:Degradation and Reactivation of Damaged Proteins. Annual Review of Genetics,1993,27:437-496.
    [98]谭琳琳,戴自祝,刘颖.空调环境对人体热感觉和神经行为功能的影响.中国卫生工程学,2003,2(4):193-195.
    [99]Juan Yu. Yingxin Zhu, Qin Ouyang, Bin Cao. An experimental study on the effects of climate characteristics on people's adaptability to the thermal environment. Journal of southeast university (English Edition),2010,26(2): 279-282.
    [100]中国建筑科学研究院.民用建筑供暖通风与空气调节设计规范(内部讨论稿).2010.
    [101]林玉莲,胡正凡.环境心理学.北京:中国建筑工业出版社,2006.
    [102]王鹏,建筑适应气候-兼论乡土建筑及其气候策略[博士学位论文].北京:清华大学,2001.
    [103]Nevins R G. Temperature-humidity chart for thermal comfort of seated persons. ASHRAE Transactions,1966,72(1):283-291.
    [104]Fanger P O, Hojbjerre J, Thomsen J O. Can winter swimming cause people to prefer lower room temperatures? International Journal of Biometeorology, 1977,21(1):44-50.
    [105]Fanger P O. Near-future prospects of the meteorological environment in developing countries in deserts and tropical areas. Improvement of comfort and resulting effects on working capacity [M]. S.W.Tromp, W.H.Weihe and Janneke J.Boima. Biometeorology. Amsterdam,1972.
    [106]Tanabe S, Kimura K, Hara T. Thermal comfort requirements during the summer season in Japan. ASHRAE Transactions,1987,93(1):564-577.
    [107]Chung T M, Tong W C. Thermal comfort study of young Chinese people in Hong Kong. Building and Environment,1990,25(4):317-328.
    [108]de Dear R J, Leow K G, Ameen A.Thermal comfort in the humid tropics. Part Ⅱ. Climate chamber experiments on thermal acceptability in Singapore. ASHRAE Trans,1991,97(1):880-886.
    [109]张国高,贺洒贞,吴扬,等.热适应与热耐受机理的探讨.同济医科大学学报,1990,19(增刊):1-3,85.
    [110][日]黑岛晨讯著,环境生理学,朱世华等译,北京:海洋出版社,1986.
    [111]Auliciems A. Towards a psychophysiological model of thermal perception. Int Journal of Biometeorology,1981,13:147-162.
    [112]Auliciems A. Thermobile controls for human comfort. The Heating and Ventilating Engineer,1984,58(665):31-34.
    [113]Nicol J F. Adaptive thermal comfort standards in the hot humid tropics. Energy and Buildings,2004,36(7):628-637.
    [114]Runming Yao, Baizhan Li, Jing Liu. A theoretical adaptive model of thermal comfort-Adaptive Predicted Mean Vote (aPMV). Building and Environment, 2009,44(10):2089-2096.
    [115]姚润明.室内气候模拟及热舒适研究[博士学位论文].重庆:重庆建筑大学,1997.
    [116]张宇峰.建筑环境人体热适应研究思路.暖通空调,2011,41(2):9-17.
    [117]黄莉,朱颖心,欧阳沁,曹彬.北京地区农宅供暖季室内热舒适研究,暖通空调,2011,41(6):83-85,105.
    [118]McIntyre D A. Design requirements for a comfortable environment. Studies in Environmental Science,1981,10,195-220.

© 2004-2018 中国地质图书馆版权所有 京ICP备05064691号 京公网安备11010802017129号

地址:北京市海淀区学院路29号 邮编:100083

电话:办公室:(+86 10)66554848;文献借阅、咨询服务、科技查新:66554700