药物防治老年髋关节周围骨折患者下肢深静脉血栓形成的效果观察
详细信息 查看官网全文
- 英文论文题名：Clinical research on low molecular heparin for preventing perioperative lower limb deep vein thrombosis in elderly hip peripheral fracture
- 论文作者：宋建锋
- 英文论文作者：Song Jianfeng
- 年：2017
- 作者机构：河南省永城市永煤集团总医院;
- 论文关键词：老年髋关节周围骨折 ; 低分子肝素 ; 深静脉血栓 ; 防治
- 英文论文关键词：elderly hip peripheral fracture ; low molecular heparin ; deep vein thrombosis ; Prevention and treatment
- 会议召开时间：2017-05-26
- 会议录名称：2017年《中国组织化学与细胞化学杂志》临床研讨会论文集
- 语种：中文
- 分类号：R687.3
- 学会代码：ZHXB
- 会议名称：2017年《中国组织化学与细胞化学杂志》临床研讨会
- 会议地点：中国湖北武汉
- 主办单位：《中国组织化学与细胞化学杂志》社有限公司
- 学会名称：《中国组织化学与细胞化学杂志》社有限公司
- 页数：2
- 文件大小：254k
- 原文格式：O
- 会议级别：全国
摘要
目的:观察低分子肝素预防老年髋关节周围骨折围术期下肢深静脉血栓(DVT)形成的临床效果。方法:选取我院2015年10月~2016年10月收治的老年髋关节周围骨折140例,随机分为观察组和对照组,每组70例。两组术前经证实未出现下肢深静脉血栓,均使用止痛药物缓解疼痛,对患肢实施皮牵引术,于入院时至术前12h采用物理疗法预防DVT,观察组在此基础上给予低分子肝素进行预防。比较两组术后DVT发生率、下肢周径差值和髋关节评分情况。结果:术后观察组发生DVT6例,发生率为8.57%;对照组发生DVT14例,发生率为20%。观察组DVT发生率低于对照组,比较有统计学差异(P<0.05)。观察组下肢周径差值为(2.91±0.84)cm,髋关节评分(90.7±6.0)分;对照组下肢周径差值为(3.55±0.90)cm,髋关节评分(84.7±5.5)分。观察组下肢周径差值和髋关节评分均明显优于对照组,比较均有统计学差异(P<0.05)。结论:在常规治疗基础上给予低分子肝素可有效预防老年髋关节周围骨折围术期下肢深静脉血栓形成,手术疗效较好,具有推广应用价值。
Objective:To observe the clinical effect of low molecular weight heparin(LMWH) on prevention of deep vein thrombosis(DVT) in elderly patients with peri-articular fractures.Methods:140 cases of hip fractures around the hip in our hospital from October 2015 to October 2016 were randomly divided into observation group and control group,70 cases in each group.The two groups were proved to have no deep venous thrombosis of the lower limbs before the operation.The patients were treated with analgesic to alleviate the pain.The patients were treated with skin traction at the time of admission and 12 hours before the operation.The observation group was given low molecular weight Heparin for prevention.The incidence of DVT,the difference of circumference of lower limb and the score of hip joint were compared between the two groups.ResultS:The incidence of DVT was 8.57%in the observation group and 14 cases in the control group,the incidence rate was 20%.The incidence of DVT in the observation group was lower than that in the control group,there was significant difference(P < 0.05).The difference of the circumference of the lower limbs was(2.91 ± 0.84) cm and the hip joint score was(90.7 ± 6.0) in the observation group and(3.55± 0.90) cm in the control group and 84.7 ± 5.5 in the control group,respectively.The difference of the circumference of the lower extremity and the hip joint score of the observation group were significantly better than those of the control group,the difference was statistically significant(P < 0.05).Conclusion:In the conventional treatment based on the low molecular weight heparin can effectively prevent the elderly around the hip fracture perioperative lower extremity deep vein thrombosis,surgical treatment is better,with the promotion and application value.
Objective:To observe the clinical effect of low molecular weight heparin(LMWH) on prevention of deep vein thrombosis(DVT) in elderly patients with peri-articular fractures.Methods:140 cases of hip fractures around the hip in our hospital from October 2015 to October 2016 were randomly divided into observation group and control group,70 cases in each group.The two groups were proved to have no deep venous thrombosis of the lower limbs before the operation.The patients were treated with analgesic to alleviate the pain.The patients were treated with skin traction at the time of admission and 12 hours before the operation.The observation group was given low molecular weight Heparin for prevention.The incidence of DVT,the difference of circumference of lower limb and the score of hip joint were compared between the two groups.ResultS:The incidence of DVT was 8.57%in the observation group and 14 cases in the control group,the incidence rate was 20%.The incidence of DVT in the observation group was lower than that in the control group,there was significant difference(P < 0.05).The difference of the circumference of the lower limbs was(2.91 ± 0.84) cm and the hip joint score was(90.7 ± 6.0) in the observation group and(3.55± 0.90) cm in the control group and 84.7 ± 5.5 in the control group,respectively.The difference of the circumference of the lower extremity and the hip joint score of the observation group were significantly better than those of the control group,the difference was statistically significant(P < 0.05).Conclusion:In the conventional treatment based on the low molecular weight heparin can effectively prevent the elderly around the hip fracture perioperative lower extremity deep vein thrombosis,surgical treatment is better,with the promotion and application value.
引文
[1]何斌,倪增良,徐增成,等.低分子肝素联合压力泵预防老年髋部骨折深静脉血栓的临床观察[J].中国医院药学杂志,2014,34(10):839-842.
[2]王琮.高龄患者骨科手术后下肢深静脉血栓的预防与治疗[J].中国医药指南,2013,3(2):158-159.
[3]李文龙.低分子肝素预防老年髋关节周围骨折围术期下肢深静脉血栓的研究[J].北方药学,2016,13(4):37.
[4]姚杰,孟尽海,王文娟,等.骨科手术病人术后下肢深静脉血栓形成的危险因素[J].中华麻醉学杂志,2013,33(4):413-416.
[5]李娟.下肢深静脉血栓相关危险因素的临床研究及其临床量化评估[D].北京:解放军医学院,2013.
[6]Chi YW,Woods TC.Clinical risk factors to predict deep venous thrombosis post-endovenous laser ablation of saphenous veins.Phlebology.2014;29(3):150-153.
[7]段士潮.老年患者髋部骨折并发DVT的危险因素分析[D].石家庄:河北医科大学,2014.
[2]王琮.高龄患者骨科手术后下肢深静脉血栓的预防与治疗[J].中国医药指南,2013,3(2):158-159.
[3]李文龙.低分子肝素预防老年髋关节周围骨折围术期下肢深静脉血栓的研究[J].北方药学,2016,13(4):37.
[4]姚杰,孟尽海,王文娟,等.骨科手术病人术后下肢深静脉血栓形成的危险因素[J].中华麻醉学杂志,2013,33(4):413-416.
[5]李娟.下肢深静脉血栓相关危险因素的临床研究及其临床量化评估[D].北京:解放军医学院,2013.
[6]Chi YW,Woods TC.Clinical risk factors to predict deep venous thrombosis post-endovenous laser ablation of saphenous veins.Phlebology.2014;29(3):150-153.
[7]段士潮.老年患者髋部骨折并发DVT的危险因素分析[D].石家庄:河北医科大学,2014.