幽门螺杆菌感染与非酒精性脂肪肝的关系
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- 英文论文题名：The relationship between Helicobacter pylori infection and non alcoholic fatty liver
- 论文作者：李晔 ; 丁丽敏 ; 刘梅
- 英文论文作者：Li Ye ; Ding Li-min ; Liu Mei ; Huadong sanatorium of Geriatrics ; Health management center Huadong sanatorium
- 年：2017
- 作者机构：华东疗养院老年病科;华东疗养院健康管理中心;
- 论文关键词：幽门螺杆菌 ; 非酒精性脂肪肝
- 英文论文关键词：Helicobacter pylori ; non alcoholic fatty liver
- 会议召开时间：2017-05-26
- 会议录名称：2017年《中国组织化学与细胞化学杂志》临床研讨会论文集
- 语种：中文
- 分类号：R575.5
- 学会代码：ZHXB
- 会议名称：2017年《中国组织化学与细胞化学杂志》临床研讨会
- 会议地点：中国湖北武汉
- 主办单位：《中国组织化学与细胞化学杂志》社有限公司
- 学会名称：《中国组织化学与细胞化学杂志》社有限公司
- 页数：2
- 文件大小：233k
- 原文格式：O
- 会议级别：全国
摘要
目的:探讨幽门螺杆菌(Hp)感染与非酒精性脂肪肝的关系。方法:1329例健康人群按13C-尿素呼气试验结果,分为Hp阳性组495例、Hp阴性组834例,比较两组脂肪肝患病率的差异。1329例健康人群按超声诊断结果,分为脂肪肝组670例、对照组(无脂肪肝组)659例,脂肪肝组、对照组又根据13C-尿素呼气试验结果,再分为Hp阳性亚组、Hp阴性亚组,比较不同亚组间收缩压(SBP)、舒张压(DBP)、甘油三酯(TG)、总胆固醇(TC)、低密度脂蛋白胆固醇(LDL-C)、高密度脂蛋白胆固醇(HDL-C)、空腹血糖(FBG)、血尿酸(UA)、血胰岛素(Ins)、胰岛素抵抗指数(HOMAIR)的差异。结果:1329例健康人群Hp阳性组、Hp阴性组脂肪肝患病率无统计学差异(P>0.05)。脂肪肝组、对照组Hp阳性亚组与Hp阴性亚组之间SBP、DBP、TG、TC、LDL-C、HDL-C、FBG、UA、Ins、HOMA-IR无统计学差异(P>0.05)。结论:幽门螺杆菌感染与非酒精性脂肪肝无关。
Objective:To investigate the relationship between Helicobacter pylori infection and non alcoholic fatty liver.Methods:1329 healthy people by13C-urea breath test results,divided into Hp positive group 495 cases,834 cases of Hp negative group,differences between the two groups in the incidence of fatty liver.1329 cases of healthy people by ultrasonic diagnosis results,divided into fatty liver group 670 cases,control group(non fatty liver group) 659 cases,fatty liver group,the control group on the basis of the 13C-urea breath test results,divided into Hp positive and Hp negative group,subgroup,Comparison of different subgroups with systolic blood pressure(SBP),diastolic blood pressure(DBP),triglyceride(TG),total cholesterol(TC),low density lipoprotein cholesterol(LDL-C),high density lipoprotein cholesterol(HDL-C),fasting blood glucose(FBG),blood uric acid(UA),insulin(Ins) index insulin resistance(HOMA-IR),the difference.Results:The prevalence of healthy people 1329 cases Hp positive,Hp negative group of fatty liver group had no statistical difference(P > 0.05).The fatty liver group,control group Hp positive group and Hp negative group between SBP,DBP,TG,TC,LDL-C,HDL-C,FBG,UA,Ins,HOMA-IR no significant difference(P > 0.05).Conclusion:Helicobacter pylori infection and non alcoholic fatty liver has nothing to do.
Objective:To investigate the relationship between Helicobacter pylori infection and non alcoholic fatty liver.Methods:1329 healthy people by13C-urea breath test results,divided into Hp positive group 495 cases,834 cases of Hp negative group,differences between the two groups in the incidence of fatty liver.1329 cases of healthy people by ultrasonic diagnosis results,divided into fatty liver group 670 cases,control group(non fatty liver group) 659 cases,fatty liver group,the control group on the basis of the 13C-urea breath test results,divided into Hp positive and Hp negative group,subgroup,Comparison of different subgroups with systolic blood pressure(SBP),diastolic blood pressure(DBP),triglyceride(TG),total cholesterol(TC),low density lipoprotein cholesterol(LDL-C),high density lipoprotein cholesterol(HDL-C),fasting blood glucose(FBG),blood uric acid(UA),insulin(Ins) index insulin resistance(HOMA-IR),the difference.Results:The prevalence of healthy people 1329 cases Hp positive,Hp negative group of fatty liver group had no statistical difference(P > 0.05).The fatty liver group,control group Hp positive group and Hp negative group between SBP,DBP,TG,TC,LDL-C,HDL-C,FBG,UA,Ins,HOMA-IR no significant difference(P > 0.05).Conclusion:Helicobacter pylori infection and non alcoholic fatty liver has nothing to do.
引文
[1]中华医学会肝病学分会脂肪肝和酒精性肝病学组.中国非酒精性脂肪性肝病诊疗指南(2010年修订版)[J].中国医学前沿杂志(电子版),2012,4(7):4-10.
[2]张万岱,胡伏莲,萧树东,等.中国自然人群幽门螺杆菌感染的流行病学调查[J].现代消化及介入诊疗,2010,15(5):265-270.
[3]徐鹏,王敦敬,刘永海.幽门螺杆菌致动脉粥样硬化的机制[J].中外医疗,2010,15:186-188.
[4]张强,张瑞彪,张玉芹,等.幽门螺杆菌感染及血清同型半胱氨酸水平与不同年龄脑梗死关系的研究[J].临床荟萃,2009,(13):1123-1125.
[5]戴光荣,冯义朝,王会丰,等.幽门螺杆菌与胰岛素抵抗之间的关系分析[J].中国误诊学杂志,2010,(24):5866-5867.
[6]赵清海,阮长武,石益海,等.幽门螺旋杆菌感染与TG、TC、HDL相关性研究[J].山东医药,2011,51(36):66-67.
[7]Naito Y,Yoshikawa T.Molecular and cellular mechanisms involved in Helicobacter pylori-induced inflammation and oxi-dativestress[J].Free Radic Biol Med,2002,33:323-336.
[8]Asian M,Horoz M,Nazliqul Y,etal.Insulin resistance in H.pylori infection and its association with oxidative stress[J].World J Gastroenterol,2006,12(42):6865-6868.
[9]任路平,宋光耀.非酒精性脂肪肝疾病发生机制研究新进展[J].中国老年学杂志,2012,32:664-666.
[2]张万岱,胡伏莲,萧树东,等.中国自然人群幽门螺杆菌感染的流行病学调查[J].现代消化及介入诊疗,2010,15(5):265-270.
[3]徐鹏,王敦敬,刘永海.幽门螺杆菌致动脉粥样硬化的机制[J].中外医疗,2010,15:186-188.
[4]张强,张瑞彪,张玉芹,等.幽门螺杆菌感染及血清同型半胱氨酸水平与不同年龄脑梗死关系的研究[J].临床荟萃,2009,(13):1123-1125.
[5]戴光荣,冯义朝,王会丰,等.幽门螺杆菌与胰岛素抵抗之间的关系分析[J].中国误诊学杂志,2010,(24):5866-5867.
[6]赵清海,阮长武,石益海,等.幽门螺旋杆菌感染与TG、TC、HDL相关性研究[J].山东医药,2011,51(36):66-67.
[7]Naito Y,Yoshikawa T.Molecular and cellular mechanisms involved in Helicobacter pylori-induced inflammation and oxi-dativestress[J].Free Radic Biol Med,2002,33:323-336.
[8]Asian M,Horoz M,Nazliqul Y,etal.Insulin resistance in H.pylori infection and its association with oxidative stress[J].World J Gastroenterol,2006,12(42):6865-6868.
[9]任路平,宋光耀.非酒精性脂肪肝疾病发生机制研究新进展[J].中国老年学杂志,2012,32:664-666.