雷贝拉唑治疗幽门螺杆菌相关性消化性溃疡43例疗效观察
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- 论文作者：张小红 ; 巩红霞 ; 党红絮 ; 贾进
- 年：2016
- 作者机构：西安中医脑病医院;
- 论文关键词：雷贝拉唑 ; 奥美拉唑 ; 幽门螺杆菌 ; 消化性溃疡
- 英文论文关键词：rabeprazole thiazole ; Omeprazole ; Helicobacter pylori ; Peptic ulcer
- 会议召开时间：2016-11-25
- 会议录名称：湖南中医药大学学报2016/专集：国际数字医学会数字中医药分会成立大会暨首届数字中医药学术交流会论文集
- 语种：中文
- 分类号：R573.1
- 学会代码：HNZY
- 会议名称：国际数字医学会数字中医药分会成立大会暨首届数字中医药学术交流会
- 会议地点：中国广东珠海
- 主办单位：国际数字医学会、Digital Chinese Medicine
- 学会名称：湖南中医药大学期刊杂志社
- 页数：1
- 文件大小：1859k
- 原文格式：D
- 会议级别：全国
摘要
目的:对比分析雷贝拉唑与奥美拉唑在幽门螺杆菌(Hp)性消化性溃疡治疗中的临床效果。方法:采用随机数字表法,将86例幽门螺杆菌相关性消化性溃疡患者随机分为对照组(实施奥美拉唑三联治疗方案)与观察组(实施雷贝拉唑三联治疗方案),两组抗菌素相同,比较两组患者的临床治疗效果。结果:观察组患者的溃疡愈合率与Hp清除率分别为93.02%和88.37%,均显著高于对照组(P<0.05),复发率和不良反应的发生率分别为2.33%和4.65%,远远低于对照组(P<0.05)。结论:与奥美拉唑相比,雷贝拉唑在幽门螺杆菌相关性消化性溃疡中的临床效果更加显著,不仅有助于提高Hp的清除率,并且可以减少复发及不良反应,值得在临床广泛应用。
objective: to analysis of rabeprazole azole and omeprazole on helicobacter pylori(Hp) in the treatment of peptic ulcer clinical effect. Methods: using random number tablemethod, 86 cases of helicobacter pylori associated with peptic ulcer were randomly divided into control group(the implementation of omeprazole triple therapy) and group(ray sanlian(scheme)) treatment, two groups of antibiotics are the same, to compare the clinical treatment effect of two groups of patients. Results: observation group of patients with ulcer healing rate and Hp clearancerate were 93.02% and 88.37% respectively, were significantly higher than that of control group(P < 0.05), and the recurrence rate and the incidence of adverse reactions were 2.33% and 4.65% respectively, far lower than the control group(P < 0.05). Conclusion: compared with omeprazole, rabeprazole azole in peptic ulcer clinical effect of the more significant correlation betweenhelicobacter pylori, not only help improve the clearance rate of Hp, and can reduce the recurrence and adverse reactions, is worth wide application in clinic.
objective: to analysis of rabeprazole azole and omeprazole on helicobacter pylori(Hp) in the treatment of peptic ulcer clinical effect. Methods: using random number tablemethod, 86 cases of helicobacter pylori associated with peptic ulcer were randomly divided into control group(the implementation of omeprazole triple therapy) and group(ray sanlian(scheme)) treatment, two groups of antibiotics are the same, to compare the clinical treatment effect of two groups of patients. Results: observation group of patients with ulcer healing rate and Hp clearancerate were 93.02% and 88.37% respectively, were significantly higher than that of control group(P < 0.05), and the recurrence rate and the incidence of adverse reactions were 2.33% and 4.65% respectively, far lower than the control group(P < 0.05). Conclusion: compared with omeprazole, rabeprazole azole in peptic ulcer clinical effect of the more significant correlation betweenhelicobacter pylori, not only help improve the clearance rate of Hp, and can reduce the recurrence and adverse reactions, is worth wide application in clinic.
引文
[1]杨智晖,潘洁,李林等.替普瑞酮联合雷贝拉唑三联疗法对老年幽门螺杆菌相关性消化性溃疡的效果[J].中国医药,2015,10(8):1166-1168.
[2]吴文海.雷贝拉唑四联疗法与枸橼酸铋雷尼替丁三联疗法治疗幽门螺杆菌相关性消化性溃疡效果对比研究[J].解放军医药杂志,2014,26(2):69-71,74.
[3]韩礼纲,纪强,高千惠等.雷贝拉唑三联疗法治疗幽门螺杆菌相关性消化性溃疡的疗效观察[J].山西医药杂志(下半月版),2013,42(10):556-557.
[4]谢润勇.雷贝拉唑三联疗法治疗幽门螺杆菌相关性消化性溃疡的临床研究[J].中国当代医药,2013,20(1):91-92.
[5]林小凤,李静玲,林汉华等.雷贝拉唑三联疗法治疗幽门螺杆菌相关性消化性溃疡的疗效观察[J].临床合理用药杂志,2012,05(7):16-17.
[6]王文雄.雷贝拉唑、克拉霉素、甲硝唑及铋剂四联疗法治疗幽门螺杆菌感染消化性溃疡的疗效观察[J].深圳中西医结合杂志,2014,24(11):119-120.
[2]吴文海.雷贝拉唑四联疗法与枸橼酸铋雷尼替丁三联疗法治疗幽门螺杆菌相关性消化性溃疡效果对比研究[J].解放军医药杂志,2014,26(2):69-71,74.
[3]韩礼纲,纪强,高千惠等.雷贝拉唑三联疗法治疗幽门螺杆菌相关性消化性溃疡的疗效观察[J].山西医药杂志(下半月版),2013,42(10):556-557.
[4]谢润勇.雷贝拉唑三联疗法治疗幽门螺杆菌相关性消化性溃疡的临床研究[J].中国当代医药,2013,20(1):91-92.
[5]林小凤,李静玲,林汉华等.雷贝拉唑三联疗法治疗幽门螺杆菌相关性消化性溃疡的疗效观察[J].临床合理用药杂志,2012,05(7):16-17.
[6]王文雄.雷贝拉唑、克拉霉素、甲硝唑及铋剂四联疗法治疗幽门螺杆菌感染消化性溃疡的疗效观察[J].深圳中西医结合杂志,2014,24(11):119-120.