危重病患者D-二聚体与APACHE Ⅱ评分及预后的关系

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• 英文论文题名：The relationship between D-dimer and APACHE Ⅱ score,prognosis in critically ill patients in emergency department
• 论文作者：温彦芳 ; 黄飞 ; 聂时南
• 英文论文作者：WEN Yan-fang ; HUANG Fei ; NIE Shi-nan ; Department of Emergency Medicine ; Nanjing General Hospital of Nanjing Military Command ; PLA
• 年：2016
• 作者机构：南京军区南京总医院(南京大学医学院附属金陵医院);
• 论文关键词：D-二聚体 ; 危重病 ; 预后 ; 急性生理学及慢性健康状况评估Ⅱ
• 英文论文关键词：D-dimer ; Serious disease ; Prognosis ; APACHE Ⅱ
• 会议召开时间：2016-06-17
• 会议录名称：2016中国中毒救治首都论坛——暨第八届全国中毒及危重症救治学术会议论文集
• 语种：中文
• 分类号：R459.7
• 学会代码：ZGDV
• 会议名称：2016中国中毒救治首都论坛——暨第八届全国中毒及危重症救治学术会议
• 会议地点：中国北京
• 主办单位：中国毒理学会中毒与救治专业委员会
• 学会名称：中国毒理学会
• 页数：3
• 文件大小：233k
• 原文格式：O
• 会议级别：全国

摘要

目的:前瞻性研究急诊危重病患者D-二聚体与急性生理学及慢性健康状况评估Ⅱ(APACHEⅡ)评分的关系及其对预后的影响。方法:选取2014年1—4月入住抢救室的1218例。(1)根据患者预后情况,以28天为终点,将患者分为存活组和死亡组,比较存活组与死亡组D-二聚体及APACHEⅡ评分的差异;(2)按入科D-二聚体水平分为5组,比较D-二聚体水平与APACHEⅡ评分和28天病死率的关系。结果:(1)存活组入科D-二聚体水平为1.67(0.74,3.04)mg/L,APACHEⅡ评分为13(10,16)分:死亡组D-二聚体水平为4.72(2.33,7.44)mg/l,APACHEⅡ评分为21(18,23)分,2组比较差异均有统计学意义(P<0.01)。(2)D-二聚体与APACHEⅡ评分呈正相关(r=0.348,P<0.01),随着D-二聚体水平增高,病死率亦随之增高(X~2=308.166,P<0.01)。结论:危重病患者D-二聚体水平与APACHEⅡ评分一致,对判断病情及预后有一定指导作用。
Objective:To study the relationship between D-dimer and acute physiology and chronic health evaluation Ⅱ(APACHE Ⅱ) score,effect on prognosis in critically ill patients in emergency department.Methods Data of 1218 patients admitted in emergency department from January 2014 to April 2014 were recruited and analyzed.(1) according to patients' prognosis,with28 days to an end,divided the patients into survival group and death group,compare the survival group and death group D-dimer and APACHE Ⅱ score difference;(2) in the section D-dimer level is divided into 5 groups,and to compare D-dimer level with APACHE Ⅱ score and the mortality of 28 day.Results(1) the survival group into the section D-dimer level of 1.67(0.74,0.74 mg/L),APACHE Ⅱ score of 13(10,16);Death group D-dimer level of 4.72 mg/L(2.33,2.33),APACHE Ⅱ score of 13(10,16),two groups compare differences were statistically significant(P < 0.01).(2)D-dimer with APACHE Ⅱ scores were positively correlated(r = 0.348,P < 0.01),with D-dimer level higher,higher case fatality rate in yingzhou(X~2 = 308.166,P < 0.01).Conclusions critical care patients with D-dimer level with APACHE Ⅱ score is consistent,has a certain guiding role to judge condition and prognosis.

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