一种用于实时监测细胞培养的微波电路

详细信息    查看官网全文

• 英文论文题名：A Microwave Circuit For Cell Culture Real-Time Monitoring
• 论文作者：李娅 ; 桂文超 ; 殷海荣 ; 宫玉彬 ; 魏彦玉 ; 徐进 ; 岳玲娜 ; 路志刚
• 英文论文作者：LI Ya ; GUI Wen-chao ; YIN Hai-rong ; GONG Yu-bin ; WEI Yan-yu ; XU Jin ; YUE Ling-na ; LU ZHi-gang ; University of Electronic Science and Technology of China
• 年：2017
• 作者机构：电子科技大学;
• 论文关键词：微波电路 ; 细胞 ; 实时监测
• 英文论文关键词：Microwave Circuit ; Cell ; Real-Time Monitor
• 会议召开时间：2017-05-08
• 会议录名称：2017年全国微波毫米波会议论文集（中册）
• 英文会议录名称：Proceedings of 2017 National Conference on Microwave and Millimeter Waves(NCMMW2017)
• 语种：中文
• 分类号：Q813.11;TN62
• 学会代码：ZDWB
• 会议名称：2017年全国微波毫米波会议
• 会议地点：中国浙江杭州
• 主办单位：中国电子学会
• 学会名称：中国电子学会微波分会
• 页数：4
• 文件大小：1061k
• 原文格式：D
• 会议级别：全国

摘要

本文设计了一种用于实时监测细胞培养的微波电路,工作于2.45GHZ。该电路包含三个部分:等分威尔金森功分器、微带电感以及整流电路。通过监测整流电路中负载两端电压的变化,可以得到培养皿的介电常数的变化。进一步,运用一定的算法就可以推测出细胞的生长状况。本文通过ADS软件进行了仿真,并将仿真模型进行加工测试。测试时,通过往培养皿中加水来改变培养皿的介电常数,验证了该电路的可行性。
In this paper, a microwave circuit that operates at 2.45 GHZ for cell culture real-time monitoring is designed. Three parts are included in the microwave circuit, and they are equal Wilkinson power divider, micro-strip inductance and rectifying circuit. By monitoring the Voltage of the load of rectifying circuit, the change of the dielectric of petri dish can be calculated. Then, the growth status of cells can be estimated by proper algorithm. The circuit is simulated and designed by ADS, and is machined and measured. In our experiment, we change the dielectric of petri dish by constantly dropping water in.

引文

[1]甘露,张志辉,吕美娜,王琳.细胞培养技术[J].中国组织工程研究,2008,12(29):5739-5742
    [2]Ahmed A.Helmy;Kamran Entesari,”A 1-8-GHz Miniaturized Spectroscopy System for Permittivity Detection and Mixture Characterization of Organic Chemicals”,IEEE Microwave Magazine,Vol.60,No.12,Nov 2012
    [3]H.Rodilla,A.Kim,J.Vukusic,G.D.M.Jeffries,K.Vukusic,A.Jesorka,and J.Stake,”Millimeter-wave dielectric spectroscopy for cell Analysis”,2014 39th Internation Conference on Infrared,Millimeter,and Terahertz waves
    [4]Katia Grenier;David Dubuc;Tong Chen;F.Artis;Mary Poupot;Jean-Jacques Fournie,”Microwave dielectric spectroscopy:An emerging analyzing technique for biological investigations at the cellular level”,2013IEEE Topical Conference on Biomedical Wireless Technologies,Networks and Sensing System,Sept2013
    [5]Francois Artis;Tong Chen;Thomas Chretie nnot;Jean-Jacques Fournie;Mary Poupot;David Dubuc;Katia Grenier,”Microwaving Biological Cells:Intracellular Analysis with Microwave Dielectric Spectroscopy”,IEEE Microwave Magazine,Vol.16,No.4,May 2015