中国女性对于化妆品成分的皮肤敏感性研究

详细信息    查看官网全文

• 英文论文题名：Skin sensitivity of cosmetic ingredients in Chinese women
• 论文作者：金西英 ; 吴美贤 ; 韩芝殷 ; 朴素潭 ; 郭一荣 ; 刘玮 ; 王学民 ; 李利 ; 赖维 ; 梁虹 ; 高兴华 ; 延在昊 ; 李存桓 ; 安水善
• 英文论文作者：Seoyoung Kim ; Mihyun Oh ; Jieun Han ; Sodam Park ; Ilyoung Kwak ; Wei Liu ; Xuemin Wang ; Li Li ; Wei Lai ; Hong Liang ; Xinghua Gao ; Jae-Ho Yeon ; JohnHwan Lee ; Susun An ; Application Technology Research Division ; AmorePacific Corporation R&D Center ; AmorePacific Corporation Shanghai R&I Center ; Department of Dermatology ; The General Hospital of the Air Force ; Skin & Cosmetic Research Department ; Shanghai Skin Disease Hospital ; Department of Dermato-Venereology ; West China Hospital ; Sichuan University ; Department of Dermatology ; The Third Affiliated Hospital of Sun Yat-Sen University ; Department of Dermatology ; Renmin Hospital of Wuhan University ; National Key Department of Dermatology and Venereology ; The First Hospital of China Medical University
• 年：2016
• 作者机构：爱茉莉太平洋研究所应用技术研究部门;爱茉莉太平洋(上海)研发有限公司;中国人民解放军空军总医院皮肤科;上海皮肤病医院皮肤与化妆品研究室;四川大学华西医院皮肤性病科;中山大学附属第三医院皮肤科;武汉大学人民医院皮肤科;中国医科大学附属第一医院皮肤性病科国家重点实验室;
• 论文关键词：中国 ; 封闭型斑贴试验 ; 皮肤刺激 ; 皮肤敏感性
• 英文论文关键词：List China ; patch test ; skin irritation ; skin sensitivity
• 会议召开时间：2016-06-15
• 会议录名称：第十一届中国化妆品学术研讨会论文集
• 英文会议录名称：The Proceedings of the 11th Seminar on Cosmetic China
• 语种：中文
• 分类号：TQ658
• 学会代码：ZGXE
• 会议名称：第十一届中国化妆品学术研讨会
• 会议地点：中国上海
• 主办单位：中国香料香精化妆品工业协会
• 学会名称：中国香料香精化妆品工业协会
• 页数：7
• 文件大小：481k
• 原文格式：O
• 会议级别：全国

摘要

中国是当今世界上新兴的最大的化妆品市场,过去的几年已显出持续的增长趋势。中国有着多样化的气候地区,所以针对不同环境中的中国女性对于化妆品成分的皮肤敏感性研究是非常必要的。本研究旨在研究中国6个不同地区(北京,沈阳,成都,武汉,上海,广州)的中国女性对于化妆品成分的皮肤敏感性和耐受性,以便针对中国女性开发安全的产品。共653名年龄在20至35岁的中国健康女性参与了本研究;其中广州109名,上海110名,武汉111名,成都107名,北京106名,沈阳110名。用于防腐剂、抗老化、美白和防晒的20种成分进行了封闭型斑贴实验。自测问卷全部由注册的受试者完成。封闭型斑贴试验结果显示,北京、沈阳和成都的受试者与其他地区的受试者相比对某些成分(防腐剂、抗衰老成分)更敏感。广州和上海的受试者皮肤刺激性评分与自述敏感性反应和化妆品不良反应均保持较低的水平。我们的研究结果表明皮肤的敏感性和化妆品耐受性受到气候不同的影响。我们建议在为中国地区研发化妆品时,应考虑不同地区不同气候下的皮肤敏感性差异。
China today is the largest emerging cosmetics market in the world.It has registered sustained growth for the past few years.China has diverse climate differences in region,so we need to identify the skin sensitivity of cosmetic ingredients with different environment in Chinese women.This study was designed to investigate the skin sensitivity and acceptability of cosmetic ingredients in Chinese women from 6 different regions(Beijing,Shenyang,Chengdu,Wuhan,Shanghai,Guangzhou) for developing safe products in Chinese women.Total of 653 healthy Chinese women aged between 20 and 35 years participated in this study:109from Guangzhou,110 from Shanghai,111 from Wuhan,107 from Chengdu,106 from Beijing,and 110 from Shenyang.Patch test was performed with 20 cosmetic ingredients with preservative,anti-aging,whitening,and sunscreen effects.The self-assessment questionnaire was completed by all registered participants.The patch test results showed that the subjects in Beijing,Shenyang and Chengdu were more sensitive to some ingredients(preservatives,anti-aging ingredients) compared to other areas.In Guangzhou and Shanghai,skin irritation score was low in consistence with self-sensitive response and cosmetic adverse rates.UV irritation rates were quite high in Wuhan,Beijing and Shenyang.However,there were no differences in self-diagnosed skin allergy rate.Our observations indicate that skin sensitivity and cosmetic acceptability were influenced by climate differences.We recommend that these differences of skin sensitivity should be considered for developing cosmetic products in China.

引文

[1]Kikuchi K,Kobayashi H,Le Fur I,Tschachler E,Tagami H:The winter season affects more severely the facial skin than the forearm skin:comparative biophysical studies conducted in the same Japanese females in later summer and winter.Exog Dermatol 2002;1:32-38.
    [2]Willis CM,Shaw S,De Lacharriere O et al.Sensitive skin:an epidemiological study.Br J Dermatol 2001;145:258-63.
    [3]Jourdain R,de Lacharriere O,Bastien P et al.Ethnic variations in self-perceived sensitive skin:epidemiological survey.Contact Dermatitis 2002;46:162-9.
    [4]An S,Lee E,Nam C et al.Investigation and identification of sensitive skin through questionnaire in Korea.In:20th World Congress of Dermatology.Paris,France.2002.
    [5]Misery L,Jean-Decoster C,Mery S,Georgescu V,Sibaud V.A new ten-item questionnaire for assessing sensitive skin:the Sensitive Scale-10.Acta Derm Venereol.2014 Nov;94(6):635-9
    [6]Christensen M,Kligman AM.An improved procedure for conducting lactic acid stinging tests on facial skin.J Soc Cosmet Chem 1996;47:1-11.
    [7]S.S,M.F,L.M.Baseline biophysical parameters in subjects with sensitive skin.Contact Dermatitis1998;38:311-5.
    [8]Lee E,An S,Choi D et al.Comparison of objective and sensory skin irritations of several cosmetic preservatives.Contact Dermatitis 2007;56:131-6.