结直肠术后吻合口瘘影响因素研究进展
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摘要
吻合口瘘是结直肠手术术后常见的并发症,不仅给患者的临床治疗效果带来一定的影响,且会使患者住院时间延长、住院费用增加。为了降低结直肠术患者术后吻合口瘘发生率,分析结直肠术后吻合口瘘影响因素具有重要意义。本文从三个方面综述结直肠术后吻合口瘘影响因素,即术前、术中、术后,为提高患者的生存率与生活质量奠定基础。
Anastomotic fistula is a common complication after colorectal surgery.It not only brings certain influence to the clinical therapeutic effect of patients,but also prolongs the length of hospitalization and increases the cost of hospitalization.In order to reduce the incidence of anastomotic fistula after colorectal surgery,it is important to analyze the influencing factors of anastomotic fistula after colorectal surgery.This article reviews the influencing factors of anastomotic fistula after colorectal surgery from three aspects:preoperative,intraoperative and post-operative,so as to lay a foundation for improving the survival rate and quality of life of patients.
Anastomotic fistula is a common complication after colorectal surgery.It not only brings certain influence to the clinical therapeutic effect of patients,but also prolongs the length of hospitalization and increases the cost of hospitalization.In order to reduce the incidence of anastomotic fistula after colorectal surgery,it is important to analyze the influencing factors of anastomotic fistula after colorectal surgery.This article reviews the influencing factors of anastomotic fistula after colorectal surgery from three aspects:preoperative,intraoperative and post-operative,so as to lay a foundation for improving the survival rate and quality of life of patients.
引文
[1]张长山,蔡丰波,魏东.腹腔镜直肠癌前切除术后吻合口瘘的危险因素分析[J].河南科技大学学报:医学版,2012,30(4):253-254.
[2]Bruce J.Systematic review of the definition and measurement of anastomotic leak after gastrointestinal surgery[J].British Journal of Surgery,2001,88(9):1157-1168.
[3]Rahbari N N,Weitz J,Hohenberger W,et al.Definition and grading of anastomotic leakage following anterior resection of the rectum:A proposal by the International Study Group of Rectal Cancer[J].Surgery,2010,147(3):339-351.
[4]李明,寇卫军,寇明文,等.低位直肠癌前切除术后吻合口漏的相关危险因素分析[J].重庆医学,2017,46(36):5123-5125.
[5]赵泽云,王爽,穆玉,等.直肠癌术后吻合口瘘影响因素及防治的研究进展[J].中国实验诊断学,2018,22(3):552-555.
[6]张伟.直肠癌患者术后出现吻合口瘘的影响因素分析[J].结直肠肛门外科,2016,22(S1):83.
[7]王昌荣,吴先龙,丁如良.直肠癌前切除术后吻合口瘘影响因素探讨[J].中华全科医学,2015,13(5):753-755.
[8]赵瑞祥.直肠癌前切除术后吻合口瘘123例诊治分析[J].中外医学研究,2011,9(33):16-17.
[9]卢星榕,池畔,蒋伟忠,等.直肠癌保肛术后迟发型吻合口瘘的影响因素及临床特点[J].中华胃肠外科杂志,2016,19(4):390-395.
[10]梅策略,黄孟,张兴有.结直肠术后并发吻合口瘘的危险因素探讨[J].国际医药卫生导报,2012,18(21):3111-3113.
[11]钟京,何志军.直肠癌根治术后发生吻合口瘘的影响因素及肠系膜下动脉结扎部位的探讨[J].中国乡村医药,2014,21(12):17-18.
[12]秦光远.结直肠癌术后吻合口瘘危险因素分析[D].石河子:石河子大学,2010.
[13]李爽.腹腔镜直肠癌前切除术后吻合口瘘的影响因素分析[J].保健医学研究与实践,2014,11(4):22-25.
[14]曾祥岳,孙振强,王海江,等.734例直肠癌术后吻合口瘘的影响因素分析[J].中华肿瘤防治杂志,2016,23(5):322-325.
[15]崔凯,潘丽,张鹏.尿毒症对结肠癌腹腔镜手术效果的影响[J].中国现代普通外科进展,2018,21(3):58-60.
[16]黄胜辉,池畔,林惠铭,等.直肠癌保肛术后迟发型吻合口瘘的影响因素及临床特点[J].中华胃肠外科杂志,2016,19(4):390-395.
[17]曾祥岳.734例直肠癌术后吻合口瘘的影响因素分析[D].新疆:新疆医科大学,2016.
[18]钟锋,高连中,卢一静.直肠癌全直肠系膜切除术后吻合口瘘的影响因素分析[J].中国肿瘤临床与康复,2014,21(2):175-177.
[19]房俊,崔小鹏,李佳,等.腹腔镜直肠癌前切除术后吻合口瘘影响因素分析[J].世界最新医学信息文摘,2017,17(22):138,143.
[20]吴红杰,邹小明.结直肠癌术后吻合口瘘的诊治及预防[J].中华结直肠疾病电子杂志,2016,5(2):171-174.
[21]王纲,程小飞,刘凡隆.低位直肠癌术后吻合口瘘防治的研究进展[J].腹部外科,2015,28(3):209-212.
[22]赵日升,汪挺.结直肠吻合口瘘术前、术中和术后危险因素的系统评价[J].中华胃肠外科杂志,2015,18(7):692.
[23]陈朝乾,张宗兵,左芦根,等.405例直肠癌术后吻合口瘘的影响因素分析[J].包头医学院学报,2018,34(4):33-35.
[24]祝鹏杰.直肠癌全系膜切除术后吻合口瘘的防治分析[J/OL].临床医药文献电子杂志,2017,4(39):7583-7585.
[25]陈凛,边识博.胃肠外科吻合器应用相关并发症及其处理[J].中国实用外科杂志,2013,33(4):278-281.
[26]袁荣华,翟晓峰.腹腔镜下结直肠癌根治术后吻合口瘘危险因素分析[J/OL].中华腔镜外科杂志:电子版,2013,6(6):51-54.
[27]郑鹏,许剑民.结直肠吻合术后吻合口瘘的防治[J].中华胃肠外科杂志,2016,19(4):379-382.
[28]秦敬.腹腔镜低位直肠癌保肛术后吻合口瘘的危险因素分析及预防对策[J].临床外科杂志,2017,25(7):531-533.
[29]邱东达.腹腔镜下治疗直肠癌术后发生吻合口瘘的危险因素及预防措施研究[J].湖南中医药大学学报,2018,24(16):1430-1431.
[30]杨向东,秦宗英.益生菌在炎症性肠病中应用的研究进展[J].结直肠肛门外科,2011,17(3):194-197.
[31]列春晓.直肠癌术后发生吻合口瘘的危险因素相关研究进展[J].饮食保健,2016,3(12):251-252.
[32]向春华,智星.直肠癌根治术后并发吻合口瘘的相关因素分析[J].中国医药导刊,2015,17(10):989-991.
[33]王薇.直肠癌行TME术后吻合口瘘的相关因素分析及防治措施[D].大连:大连医科大学,2014.
[34]Choi H K,Law W L,Ho J W C.Leakage After Resection and Intraperitoneal Anastomosis for Colorectal Malignancy:Analysis of Risk Factors[J].Diseases of the Colon&Rectum,2006,49(11):1719-1725.
[35]Buchs N C,Gervaz P,Secic M,et al.Incidence,consequences,and risk factors for anastomotic dehiscence after colorectal surgery:a prospective monocentric study[J].International Journal of Colorectal Disease,2008,23(3):265-270.
[36]Tadros T,Wobbes T,Hendriks T.Blood Transfusion Impairs the Healing of Experimental Intestinal Anastomoses[J].Annals of Surgery,1992,215(3):276-281.
[2]Bruce J.Systematic review of the definition and measurement of anastomotic leak after gastrointestinal surgery[J].British Journal of Surgery,2001,88(9):1157-1168.
[3]Rahbari N N,Weitz J,Hohenberger W,et al.Definition and grading of anastomotic leakage following anterior resection of the rectum:A proposal by the International Study Group of Rectal Cancer[J].Surgery,2010,147(3):339-351.
[4]李明,寇卫军,寇明文,等.低位直肠癌前切除术后吻合口漏的相关危险因素分析[J].重庆医学,2017,46(36):5123-5125.
[5]赵泽云,王爽,穆玉,等.直肠癌术后吻合口瘘影响因素及防治的研究进展[J].中国实验诊断学,2018,22(3):552-555.
[6]张伟.直肠癌患者术后出现吻合口瘘的影响因素分析[J].结直肠肛门外科,2016,22(S1):83.
[7]王昌荣,吴先龙,丁如良.直肠癌前切除术后吻合口瘘影响因素探讨[J].中华全科医学,2015,13(5):753-755.
[8]赵瑞祥.直肠癌前切除术后吻合口瘘123例诊治分析[J].中外医学研究,2011,9(33):16-17.
[9]卢星榕,池畔,蒋伟忠,等.直肠癌保肛术后迟发型吻合口瘘的影响因素及临床特点[J].中华胃肠外科杂志,2016,19(4):390-395.
[10]梅策略,黄孟,张兴有.结直肠术后并发吻合口瘘的危险因素探讨[J].国际医药卫生导报,2012,18(21):3111-3113.
[11]钟京,何志军.直肠癌根治术后发生吻合口瘘的影响因素及肠系膜下动脉结扎部位的探讨[J].中国乡村医药,2014,21(12):17-18.
[12]秦光远.结直肠癌术后吻合口瘘危险因素分析[D].石河子:石河子大学,2010.
[13]李爽.腹腔镜直肠癌前切除术后吻合口瘘的影响因素分析[J].保健医学研究与实践,2014,11(4):22-25.
[14]曾祥岳,孙振强,王海江,等.734例直肠癌术后吻合口瘘的影响因素分析[J].中华肿瘤防治杂志,2016,23(5):322-325.
[15]崔凯,潘丽,张鹏.尿毒症对结肠癌腹腔镜手术效果的影响[J].中国现代普通外科进展,2018,21(3):58-60.
[16]黄胜辉,池畔,林惠铭,等.直肠癌保肛术后迟发型吻合口瘘的影响因素及临床特点[J].中华胃肠外科杂志,2016,19(4):390-395.
[17]曾祥岳.734例直肠癌术后吻合口瘘的影响因素分析[D].新疆:新疆医科大学,2016.
[18]钟锋,高连中,卢一静.直肠癌全直肠系膜切除术后吻合口瘘的影响因素分析[J].中国肿瘤临床与康复,2014,21(2):175-177.
[19]房俊,崔小鹏,李佳,等.腹腔镜直肠癌前切除术后吻合口瘘影响因素分析[J].世界最新医学信息文摘,2017,17(22):138,143.
[20]吴红杰,邹小明.结直肠癌术后吻合口瘘的诊治及预防[J].中华结直肠疾病电子杂志,2016,5(2):171-174.
[21]王纲,程小飞,刘凡隆.低位直肠癌术后吻合口瘘防治的研究进展[J].腹部外科,2015,28(3):209-212.
[22]赵日升,汪挺.结直肠吻合口瘘术前、术中和术后危险因素的系统评价[J].中华胃肠外科杂志,2015,18(7):692.
[23]陈朝乾,张宗兵,左芦根,等.405例直肠癌术后吻合口瘘的影响因素分析[J].包头医学院学报,2018,34(4):33-35.
[24]祝鹏杰.直肠癌全系膜切除术后吻合口瘘的防治分析[J/OL].临床医药文献电子杂志,2017,4(39):7583-7585.
[25]陈凛,边识博.胃肠外科吻合器应用相关并发症及其处理[J].中国实用外科杂志,2013,33(4):278-281.
[26]袁荣华,翟晓峰.腹腔镜下结直肠癌根治术后吻合口瘘危险因素分析[J/OL].中华腔镜外科杂志:电子版,2013,6(6):51-54.
[27]郑鹏,许剑民.结直肠吻合术后吻合口瘘的防治[J].中华胃肠外科杂志,2016,19(4):379-382.
[28]秦敬.腹腔镜低位直肠癌保肛术后吻合口瘘的危险因素分析及预防对策[J].临床外科杂志,2017,25(7):531-533.
[29]邱东达.腹腔镜下治疗直肠癌术后发生吻合口瘘的危险因素及预防措施研究[J].湖南中医药大学学报,2018,24(16):1430-1431.
[30]杨向东,秦宗英.益生菌在炎症性肠病中应用的研究进展[J].结直肠肛门外科,2011,17(3):194-197.
[31]列春晓.直肠癌术后发生吻合口瘘的危险因素相关研究进展[J].饮食保健,2016,3(12):251-252.
[32]向春华,智星.直肠癌根治术后并发吻合口瘘的相关因素分析[J].中国医药导刊,2015,17(10):989-991.
[33]王薇.直肠癌行TME术后吻合口瘘的相关因素分析及防治措施[D].大连:大连医科大学,2014.
[34]Choi H K,Law W L,Ho J W C.Leakage After Resection and Intraperitoneal Anastomosis for Colorectal Malignancy:Analysis of Risk Factors[J].Diseases of the Colon&Rectum,2006,49(11):1719-1725.
[35]Buchs N C,Gervaz P,Secic M,et al.Incidence,consequences,and risk factors for anastomotic dehiscence after colorectal surgery:a prospective monocentric study[J].International Journal of Colorectal Disease,2008,23(3):265-270.
[36]Tadros T,Wobbes T,Hendriks T.Blood Transfusion Impairs the Healing of Experimental Intestinal Anastomoses[J].Annals of Surgery,1992,215(3):276-281.