可降解包装材料聚羟基烷酸酯合成工艺及影响因素的研究进展
|
摘要
目的综述可降解包装材料聚羟基烷酸酯(Polyhydroxyalkanoates,简称PHAs或PHA)的主要合成工艺、影响PHA产率的因素及其在包装工业领域上的应用研究进展。方法通过对国内外的研究现状和研究成果进行分析总结,介绍PHA的主要合成工艺,微生物法合成PHA产量的影响因素及PHA在包装方面的应用。结果 PHA合成工艺、碳源种类和浓度、氮磷源浓度、pH值、溶解氧浓度和温度对合成PHA的产量有很大影响,其中碳源种类不同还会使形成PHA的单体及单体在PHA中的比例不同,形成具有不同性质的PHA。PHA因其性能的多样性而广泛应用于包装领域。结论优化PHA的合成工艺及影响因素,能有效提高PHA产量或降低PHA生产成本。目前,以真实废弃物为底物的活性污泥系统生产PHA的研究还不够深入,由于PHA作为可降解的包装材料在包装领域具有显著的发展前景,因此,优化PHA合成工艺和影响因素是今后值得关注的重点方向。
The work aims to summarize the research progress of the main synthetic technology of degradable packaging material Polyhydroxyalkanoates(PHAs or PHA), the factors affecting the yield of PHA and the application in packaging industry of PHA. Based on the analysis and summary of the research status and achievements at home and abroad, the main synthetic process of PHA, the influencing factors on the yield of PHA by microbial synthesis and the application of PHA in packaging were introduced. PHA synthesis process, types and concentration of carbon sources, concentration of nitrogen and phosphorus sources, pH value, concentration of dissolved oxygen and temperature had a great impact on the yield of PHA. Different types of carbon sources also made the monomers of PHA different, and the proportion of monomers in PHA was different which formed PHA with different properties. Due to the diversity of PHA performance, it could be widely applied to packaging. Optimizing the synthesis process and influencing factors of PHA can effectively increase the yield of PHA or reduce the production cost of PHA. However, the research on the production of PHA by activated sludge system with real waste as substrate is not deep enough. As a degradable packaging material, PHA has significant development prospects in the field of packaging. Therefore, optimizing the synthesis process and influencing factors of PHA is the focus of attention in the future.
The work aims to summarize the research progress of the main synthetic technology of degradable packaging material Polyhydroxyalkanoates(PHAs or PHA), the factors affecting the yield of PHA and the application in packaging industry of PHA. Based on the analysis and summary of the research status and achievements at home and abroad, the main synthetic process of PHA, the influencing factors on the yield of PHA by microbial synthesis and the application of PHA in packaging were introduced. PHA synthesis process, types and concentration of carbon sources, concentration of nitrogen and phosphorus sources, pH value, concentration of dissolved oxygen and temperature had a great impact on the yield of PHA. Different types of carbon sources also made the monomers of PHA different, and the proportion of monomers in PHA was different which formed PHA with different properties. Due to the diversity of PHA performance, it could be widely applied to packaging. Optimizing the synthesis process and influencing factors of PHA can effectively increase the yield of PHA or reduce the production cost of PHA. However, the research on the production of PHA by activated sludge system with real waste as substrate is not deep enough. As a degradable packaging material, PHA has significant development prospects in the field of packaging. Therefore, optimizing the synthesis process and influencing factors of PHA is the focus of attention in the future.
引文
[1]陈玮.利用活性污泥混合菌群合成聚羟基烷酸脂的研究[D].哈尔滨:哈尔滨工业大学,2010.CHEN Wei.Research on Polyhydroxyalkanoate Synthesis with Activated Sludge Mixed[D].Harbin:Harbin Institute of Technology,2010.
[2]AVEROUS L,POLLET E.Biodegradable Polymers[M].Principles of Tissue Engineering,2012.
[3]王颖,陈国强.合成生物学技术在聚羟基脂肪酸酯PHA生产中的应用[J].中国科学,2015,45(10):1003-1014.WANG Ying,CHEN Guo-qiang.Application of Synthetic Biology for the Production of Polyhydroxyalkanoates[J].Science China,2015,45(10):1003-1014.
[4]郭子瑞,黄龙,陈志强,等.活性污泥合成聚羟基脂肪酸酯工艺过程研究进展[J].哈尔滨工业大学学报,2016,48(2):1-8.GUO Zi-rui,HUANG Long,CHEN Zhi-qiang,et al.Advances in Polyhydroxyalkanes Synthesis by Activated Sludge[J].Journal of Harbin Institute of Technology,2016,48(2):1-8.
[5]IWAMOTO Y,SATOH H,MINO T,et al.Production of Biodegradable Plastic PHA by Excess Sludge from Anadrobic-aerobic Activated Sludge Process[J].Doboku Gakkai Ronbunshuu G,2010,31(5):535-540.
[6]JIANG Y M,CHEN Y G.The Effects of the Ratio of Propionate to Acetate on the Transformation and Composition of Polyhydroxyalkanoates with Enriched Cultures of Glycogen-accumulating Organisms[J].Environmental Technology,2009,30(3):241-249.
[7]ZENG R J,LOOSDRECHT M C M V,YUAN Z,et al.Metabolic Model for Glycogen-Accumulating Organisms in Anaerobic/Aerobic Activated Sludge Systems[J].Biotechnology&Bioengineering,2010,81(1):92-105.
[8]贾倩倩.复合菌群利用模拟污泥水解液合成聚羟基脂肪酸酯的研究[D].北京:清华大学,2013.JIA Qian-qian.Study on Synthesis of Polyhydroxyalkanoates(PHA)by Bacterial Consortium from Simulated Excess Sludge Fermentation Liquid[D].Beijing:Tsinghua University,2013.
[9]BLUNT W,DARTIAILH C,SPARLING R,et al.Microaerophilic Environments Improve the Productivity of Medium Chain Length Polyhydroxyalkanoate Biosynthesis from Fatty Acids in Pseudomonas putida,LS46[J].Process Biochemistry,2017,59:18-25.
[10]AMULYA K,REDDY M V,ROHIT M V,et al.Wastewater as Renewable Feedstock for Bioplastics Production:Understanding the Role of Reactor Microenvironment and System pH[J].Journal of Cleaner Production,2015,112(5):4618-4627.
[11]CHEN Z,HUANG L,WEN Q,et al.Efficient Polyhydroxyalkanoate(PHA)Accumulation by a New Continuous Feeding Mode in Three-stage Mixed Microbial Culture(MMC)PHA Production Process[J].Journal of Biotechnology,2015,209(1):68-75.
[12]CHEN Z,GUO Z,WEN Q,et al.A New Method for Polyhydroxyalkanoate(PHA)Accumulating Bacteria Selection under Physical Selective Pressure[J].International Journal of Biological Macromolecules,2015,72:1329-1334.
[13]AMULYA K,JUKURI S,MOHAN S V.Sustainable Multistage Process for Enhanced Productivity of Bioplastics from Waste Remediation through Aerobic Dynamic Feeding Strategy:Process Integration for Up-scaling[J].Bioresource Technology,2015,188:231-239.
[14]GUERRA-BLANCO P,CORTES O,POZNYAK T,et al.Polyhydroxyalkanoates(PHA)Production by Photoheterotrophic Microbial Consortia:Effect of Culture Conditions over Microbial Population and Biopolymer Yield and Composition[J].European Polymer Journal,2017,98:94-104.
[15]GAO J,RAMSAY J A,RAMSAY B A.Fed-batch Production of Poly-3-hydroxydecanoate from Decanoic Acid[J].Journal of Biotechnology,2016,218:102-107.
[16]SHI Y,YAN X,LI Q,et al.Directed Bioconversion of Kraft Lignin to Polyhydroxyalkanoate by Cupriavidus Basilensis,B-8 without Any Pretreatment[J].Process Biochemistry,2016,52:238-242.
[17]陈国强.生物高分子材料聚羟基脂肪酸酯(PHA)开发现状及产业化前景分析[J].化工新型材料,2010,38(10):1-7.CHEN Guo-qiang.Current Status and Industrialization of Biopolyesters Polyhydroxyalkan Oate(PHA)[J].New Chemical Materials,2010,38(10):1-7.
[18]BURNIOL-FIGOLS A,VARRONE C,DAUGAARD AE,et al.Polyhydroxyalkanoates(PHA)Production from Fermented Crude Glycerol:Study on the Conversion of 1,3-propanediol to PHA in Mixed Microbial Consortia[J].Water Research,2017,128:255-266.
[19]RAY S,PRAJAPATI V,PATEL K,et al.Optimization and Characterization of PHA from Isolate Pannonibacter Phragmitetus,ERC8 Using Glycerol Waste[J].International Journal of Biological Macromolecules,2016,86:741-749.
[20]KYNADI A S,TV S.Formulation and Optimization of a Novel Media Comprising Rubber Seed Oil for PHAProduction[J].Industrial Crops&Products,2017,105:156-163.
[21]HUSCHNER F,GROUSSEAU E,BRIGHAM C J,et al.Development of a Feeding Strategy for High Cell and PHA Density Fed-batch Fermentation of Ralstonia Eutropha,H16 from Organic Acids and their Salts[J].Process Biochemistry,2015,50(2):165-172.
[22]SAWANT S S,TRAN T K,SALUNKE B K,et al.Potential of Saccharophagus Degradans for Production of Polyhydroxyalkanoates Using Cellulose[J].Process Biochemistry,2017,57:50-56.
[23]BERA A,DUBEY S,BHAYANI K,et al.Microbial Synthesis of Polyhydroxyalkanoate Using Seaweed-derived Crude Levulinic Acid as Co-nutrient[J].International Journal of Biological Macromolecules,2015,72:487-494.
[24]AHN J,JHO E H,NAM K.Effect of Acid-digested Rice Straw Waste Feeding Methods on the 3HV Fraction of Bacterial Poly(3-hydroxybutyrate-co-3-hydroxyvalerate)Production[J].Process Biochemistry,2016,51(12):2119-2126.
[25]OH Y H,LEE S H,JANG Y A,et al.Development of Rice Bran Treatment Process and Its Use for the Synthesis of Polyhydroxyalkanoates from Rice Bran Hydrolysate Solution[J].Bioresource Technology,2015,181:283-290.
[26]刘英杰,贾晓强,闻建平,等.混合菌群合成聚羟基脂肪酸酯研究进展[J].化工进展,2014,33(10):2729-2734.LIU Yin-jie,JIA Xiao-qiang,WEN Jian-ping,et al.Recent Advances in Polyhydroxyalkanoates Production by Mixed Cultures[J].Chemical Industry and Engineering Progress,2014,33(10):2729-2734.
[27]KORKAKAKI E,VAN M L,KLEEREBEZEM R.Impact of Phosphate Limitation on PHA Production in a Feast-famine Process[J].Water Research,2017,126:472-480.
[28]VALENTINO F,KARABEGOVIC L,MAJONE M,et al.Polyhydroxyalkanoate(PHA)Storage within a Mixed-culture Biomass with Simultaneous Growth as a Function of Accumulation Substrate Nitrogen and Phosphorus Levels[J].Water Research,2015,77:49-63.
[29]KOURMENTZA C,NTAIKOU I,LYBERATOS G,et al.Polyhydroxyalkanoates from Pseudomonas Sp.using Synthetic and Olive Mill Wastewater under Limiting Conditions[J].International Journal of Biological Macromolecules,2015,74:202-210.
[30]任中佳,王亚宜,耿军军.活性污泥胞内物质合成影响因素的研究进展[J].环境污染与防治,2011,33(4):74-80.REN Zhong-jia,WANG Ya-yi,GENG Jun-jun.Key Factors Impacting Polyhydroxyalkanoates Accumulation by Activated Sludge[J].Environmental Pollution&Control,2011,33(4):74-80.
[31]INOUE D,SUZUKI Y,SAWADA K,et al.Polyhydroxyalkanoate Accumulation Ability and Associated Microbial Community in Activated Sludge-derived Acetate-fed Microbial Cultures Enriched under Different Temperature and pH Conditions[J].Journal of Bioscience&Bioengineering,2017,125(3):339-345.
[32]LEE W S,CHUA A S M,YEOH H K,et al.Strategy for the Biotransformation of Fermented Palm Oil Mill Effluent into Biodegradable Polyhydroxyalkanoates by Activated Sludge[J].Chemical Engineering Journal,2015,269:288-297.
[33]李小虎,薛鹏程,孙佳佳.活性污泥胞内聚合物的合成影响因素初探[J].环境与发展,2017,29(10):127-128.LI Xiao-hu,XUE Peng-cheng,SUN Jia-jia.Preliminary Study on Synthesis Factors of Intracellular Polymeric Substance in Activated Sludge[J].Environment and Development,2017,29(10):127-128.
[34]WANG X,OEHMEN A,FREITAS E B,et al.The Link of Feast-phase Dissolved Oxygen(DO)with Substrate Competition and Microbial Selection in PHA Production[J].Water Research,2017,112:269-278.
[35]VJAYAN T,VADIVELU V M.Effect of Famine-phase Reduced Aeration on Polyhydroxyalkanoate Accumulation in Aerobic Granules[J].Bioresour Technol,2017,245:970-976.
[36]KINYUA M N,MILLER M W,WETT B,et al.Polyhydroxyalkanoates,Triacylglycerides and Glycogen in a High Rate Activated Sludge A-stage System[J].Chemical Engineering Journal,2017,316:350-360.
[37]SILVA L F,TACIRO M K,RAICHER G,et al.Perspectives on the Production of Polyhydroxyalkanoates in Biorefineries Associated with the Production of Sugar and Ethanol[J].International Journal of Biological Macromolecules,2014,71:2-7.
[38]GüLSAH K,GüLNUR K,MIKHAEL B,et al.Potential of Polyhydroxyalkanoate(PHA)Polymers Family as Substitutes of Petroleum Based Polymers for Packaging Applications and Solutions Brought by Their Composites to form Barrier Materials[J].Pure and Applied Chemistry,2017,89(12):1841-1848.
[39]AVéROUS L,POLLET E.Biodegradable Polymers[M].Principles of Tissue Engineering,2012.
[40]PBS A,MALAFAIA C B.Perspectives on the Production,Structural Characteristics and Potential Applications of Bioplastics Derived from Polyhydroxyalkanoates[J].International Journal of Biological Macromolecules,2017,107:615-625.
[41]FABRA M J,LOPEZ-RUBIO A,LAGARON J M.On the Use of Different Hydrocolloids as Electrospun Adhesive Interlayers to Enhance the Barrier Properties of Polyhydroxyalkanoates of Interest in Fully Renewable Food Packaging Concepts[J].Food Hydrocolloids,2014,39(8):77-84.
[42]CHERPINSKI A,TORRES-GINER S,VARTIAINENJ,et al.Improving the Water Resistance of Nanocellulose-based Films with Polyhydroxyalkanoates Processed by the Electrospinning Coating Technique[J].Cellulose,2018,25(2):1-17.
[43]ZHAO C,LI J,HE B,et al.Fabrication of Hydrophobic Biocomposite by Combining Cellulosic Fibers with Polyhydroxyalkanoate[J].Cellulose,2017,24(5):2265-2274.
[44]BUCCI D Z,TAVARES L B B,SELL I.PHB Packaging for the Storage of Food Products[J].Polymer Testing,2005,24(5):564-571.
[2]AVEROUS L,POLLET E.Biodegradable Polymers[M].Principles of Tissue Engineering,2012.
[3]王颖,陈国强.合成生物学技术在聚羟基脂肪酸酯PHA生产中的应用[J].中国科学,2015,45(10):1003-1014.WANG Ying,CHEN Guo-qiang.Application of Synthetic Biology for the Production of Polyhydroxyalkanoates[J].Science China,2015,45(10):1003-1014.
[4]郭子瑞,黄龙,陈志强,等.活性污泥合成聚羟基脂肪酸酯工艺过程研究进展[J].哈尔滨工业大学学报,2016,48(2):1-8.GUO Zi-rui,HUANG Long,CHEN Zhi-qiang,et al.Advances in Polyhydroxyalkanes Synthesis by Activated Sludge[J].Journal of Harbin Institute of Technology,2016,48(2):1-8.
[5]IWAMOTO Y,SATOH H,MINO T,et al.Production of Biodegradable Plastic PHA by Excess Sludge from Anadrobic-aerobic Activated Sludge Process[J].Doboku Gakkai Ronbunshuu G,2010,31(5):535-540.
[6]JIANG Y M,CHEN Y G.The Effects of the Ratio of Propionate to Acetate on the Transformation and Composition of Polyhydroxyalkanoates with Enriched Cultures of Glycogen-accumulating Organisms[J].Environmental Technology,2009,30(3):241-249.
[7]ZENG R J,LOOSDRECHT M C M V,YUAN Z,et al.Metabolic Model for Glycogen-Accumulating Organisms in Anaerobic/Aerobic Activated Sludge Systems[J].Biotechnology&Bioengineering,2010,81(1):92-105.
[8]贾倩倩.复合菌群利用模拟污泥水解液合成聚羟基脂肪酸酯的研究[D].北京:清华大学,2013.JIA Qian-qian.Study on Synthesis of Polyhydroxyalkanoates(PHA)by Bacterial Consortium from Simulated Excess Sludge Fermentation Liquid[D].Beijing:Tsinghua University,2013.
[9]BLUNT W,DARTIAILH C,SPARLING R,et al.Microaerophilic Environments Improve the Productivity of Medium Chain Length Polyhydroxyalkanoate Biosynthesis from Fatty Acids in Pseudomonas putida,LS46[J].Process Biochemistry,2017,59:18-25.
[10]AMULYA K,REDDY M V,ROHIT M V,et al.Wastewater as Renewable Feedstock for Bioplastics Production:Understanding the Role of Reactor Microenvironment and System pH[J].Journal of Cleaner Production,2015,112(5):4618-4627.
[11]CHEN Z,HUANG L,WEN Q,et al.Efficient Polyhydroxyalkanoate(PHA)Accumulation by a New Continuous Feeding Mode in Three-stage Mixed Microbial Culture(MMC)PHA Production Process[J].Journal of Biotechnology,2015,209(1):68-75.
[12]CHEN Z,GUO Z,WEN Q,et al.A New Method for Polyhydroxyalkanoate(PHA)Accumulating Bacteria Selection under Physical Selective Pressure[J].International Journal of Biological Macromolecules,2015,72:1329-1334.
[13]AMULYA K,JUKURI S,MOHAN S V.Sustainable Multistage Process for Enhanced Productivity of Bioplastics from Waste Remediation through Aerobic Dynamic Feeding Strategy:Process Integration for Up-scaling[J].Bioresource Technology,2015,188:231-239.
[14]GUERRA-BLANCO P,CORTES O,POZNYAK T,et al.Polyhydroxyalkanoates(PHA)Production by Photoheterotrophic Microbial Consortia:Effect of Culture Conditions over Microbial Population and Biopolymer Yield and Composition[J].European Polymer Journal,2017,98:94-104.
[15]GAO J,RAMSAY J A,RAMSAY B A.Fed-batch Production of Poly-3-hydroxydecanoate from Decanoic Acid[J].Journal of Biotechnology,2016,218:102-107.
[16]SHI Y,YAN X,LI Q,et al.Directed Bioconversion of Kraft Lignin to Polyhydroxyalkanoate by Cupriavidus Basilensis,B-8 without Any Pretreatment[J].Process Biochemistry,2016,52:238-242.
[17]陈国强.生物高分子材料聚羟基脂肪酸酯(PHA)开发现状及产业化前景分析[J].化工新型材料,2010,38(10):1-7.CHEN Guo-qiang.Current Status and Industrialization of Biopolyesters Polyhydroxyalkan Oate(PHA)[J].New Chemical Materials,2010,38(10):1-7.
[18]BURNIOL-FIGOLS A,VARRONE C,DAUGAARD AE,et al.Polyhydroxyalkanoates(PHA)Production from Fermented Crude Glycerol:Study on the Conversion of 1,3-propanediol to PHA in Mixed Microbial Consortia[J].Water Research,2017,128:255-266.
[19]RAY S,PRAJAPATI V,PATEL K,et al.Optimization and Characterization of PHA from Isolate Pannonibacter Phragmitetus,ERC8 Using Glycerol Waste[J].International Journal of Biological Macromolecules,2016,86:741-749.
[20]KYNADI A S,TV S.Formulation and Optimization of a Novel Media Comprising Rubber Seed Oil for PHAProduction[J].Industrial Crops&Products,2017,105:156-163.
[21]HUSCHNER F,GROUSSEAU E,BRIGHAM C J,et al.Development of a Feeding Strategy for High Cell and PHA Density Fed-batch Fermentation of Ralstonia Eutropha,H16 from Organic Acids and their Salts[J].Process Biochemistry,2015,50(2):165-172.
[22]SAWANT S S,TRAN T K,SALUNKE B K,et al.Potential of Saccharophagus Degradans for Production of Polyhydroxyalkanoates Using Cellulose[J].Process Biochemistry,2017,57:50-56.
[23]BERA A,DUBEY S,BHAYANI K,et al.Microbial Synthesis of Polyhydroxyalkanoate Using Seaweed-derived Crude Levulinic Acid as Co-nutrient[J].International Journal of Biological Macromolecules,2015,72:487-494.
[24]AHN J,JHO E H,NAM K.Effect of Acid-digested Rice Straw Waste Feeding Methods on the 3HV Fraction of Bacterial Poly(3-hydroxybutyrate-co-3-hydroxyvalerate)Production[J].Process Biochemistry,2016,51(12):2119-2126.
[25]OH Y H,LEE S H,JANG Y A,et al.Development of Rice Bran Treatment Process and Its Use for the Synthesis of Polyhydroxyalkanoates from Rice Bran Hydrolysate Solution[J].Bioresource Technology,2015,181:283-290.
[26]刘英杰,贾晓强,闻建平,等.混合菌群合成聚羟基脂肪酸酯研究进展[J].化工进展,2014,33(10):2729-2734.LIU Yin-jie,JIA Xiao-qiang,WEN Jian-ping,et al.Recent Advances in Polyhydroxyalkanoates Production by Mixed Cultures[J].Chemical Industry and Engineering Progress,2014,33(10):2729-2734.
[27]KORKAKAKI E,VAN M L,KLEEREBEZEM R.Impact of Phosphate Limitation on PHA Production in a Feast-famine Process[J].Water Research,2017,126:472-480.
[28]VALENTINO F,KARABEGOVIC L,MAJONE M,et al.Polyhydroxyalkanoate(PHA)Storage within a Mixed-culture Biomass with Simultaneous Growth as a Function of Accumulation Substrate Nitrogen and Phosphorus Levels[J].Water Research,2015,77:49-63.
[29]KOURMENTZA C,NTAIKOU I,LYBERATOS G,et al.Polyhydroxyalkanoates from Pseudomonas Sp.using Synthetic and Olive Mill Wastewater under Limiting Conditions[J].International Journal of Biological Macromolecules,2015,74:202-210.
[30]任中佳,王亚宜,耿军军.活性污泥胞内物质合成影响因素的研究进展[J].环境污染与防治,2011,33(4):74-80.REN Zhong-jia,WANG Ya-yi,GENG Jun-jun.Key Factors Impacting Polyhydroxyalkanoates Accumulation by Activated Sludge[J].Environmental Pollution&Control,2011,33(4):74-80.
[31]INOUE D,SUZUKI Y,SAWADA K,et al.Polyhydroxyalkanoate Accumulation Ability and Associated Microbial Community in Activated Sludge-derived Acetate-fed Microbial Cultures Enriched under Different Temperature and pH Conditions[J].Journal of Bioscience&Bioengineering,2017,125(3):339-345.
[32]LEE W S,CHUA A S M,YEOH H K,et al.Strategy for the Biotransformation of Fermented Palm Oil Mill Effluent into Biodegradable Polyhydroxyalkanoates by Activated Sludge[J].Chemical Engineering Journal,2015,269:288-297.
[33]李小虎,薛鹏程,孙佳佳.活性污泥胞内聚合物的合成影响因素初探[J].环境与发展,2017,29(10):127-128.LI Xiao-hu,XUE Peng-cheng,SUN Jia-jia.Preliminary Study on Synthesis Factors of Intracellular Polymeric Substance in Activated Sludge[J].Environment and Development,2017,29(10):127-128.
[34]WANG X,OEHMEN A,FREITAS E B,et al.The Link of Feast-phase Dissolved Oxygen(DO)with Substrate Competition and Microbial Selection in PHA Production[J].Water Research,2017,112:269-278.
[35]VJAYAN T,VADIVELU V M.Effect of Famine-phase Reduced Aeration on Polyhydroxyalkanoate Accumulation in Aerobic Granules[J].Bioresour Technol,2017,245:970-976.
[36]KINYUA M N,MILLER M W,WETT B,et al.Polyhydroxyalkanoates,Triacylglycerides and Glycogen in a High Rate Activated Sludge A-stage System[J].Chemical Engineering Journal,2017,316:350-360.
[37]SILVA L F,TACIRO M K,RAICHER G,et al.Perspectives on the Production of Polyhydroxyalkanoates in Biorefineries Associated with the Production of Sugar and Ethanol[J].International Journal of Biological Macromolecules,2014,71:2-7.
[38]GüLSAH K,GüLNUR K,MIKHAEL B,et al.Potential of Polyhydroxyalkanoate(PHA)Polymers Family as Substitutes of Petroleum Based Polymers for Packaging Applications and Solutions Brought by Their Composites to form Barrier Materials[J].Pure and Applied Chemistry,2017,89(12):1841-1848.
[39]AVéROUS L,POLLET E.Biodegradable Polymers[M].Principles of Tissue Engineering,2012.
[40]PBS A,MALAFAIA C B.Perspectives on the Production,Structural Characteristics and Potential Applications of Bioplastics Derived from Polyhydroxyalkanoates[J].International Journal of Biological Macromolecules,2017,107:615-625.
[41]FABRA M J,LOPEZ-RUBIO A,LAGARON J M.On the Use of Different Hydrocolloids as Electrospun Adhesive Interlayers to Enhance the Barrier Properties of Polyhydroxyalkanoates of Interest in Fully Renewable Food Packaging Concepts[J].Food Hydrocolloids,2014,39(8):77-84.
[42]CHERPINSKI A,TORRES-GINER S,VARTIAINENJ,et al.Improving the Water Resistance of Nanocellulose-based Films with Polyhydroxyalkanoates Processed by the Electrospinning Coating Technique[J].Cellulose,2018,25(2):1-17.
[43]ZHAO C,LI J,HE B,et al.Fabrication of Hydrophobic Biocomposite by Combining Cellulosic Fibers with Polyhydroxyalkanoate[J].Cellulose,2017,24(5):2265-2274.
[44]BUCCI D Z,TAVARES L B B,SELL I.PHB Packaging for the Storage of Food Products[J].Polymer Testing,2005,24(5):564-571.