自拟益脾清肺汤对支气管扩张的治疗作用及对炎性因子含量的影响
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摘要
目的探究自拟益脾清肺汤对支气管扩张的治疗作用及对炎性因子含量的影响。方法选取我院2016年3月至2018年8月收治的94例支气管扩张患者作为研究对象,随机分为对照组47例和观察组47例,对照组采用常规西医治疗,观察组在对照组的基础上,采用自拟益脾清肺汤治疗,比较两组的临床疗效和各项炎性因子水平。结果对照组临床治疗总有效率为82.98%(39/47),观察组临床治疗总有效率为95.74%(45/47),差异有统计学意义(P<0.05)。治疗前,对照组和观察组CRP、IL-6、TNF-α水平差异无统计学意义(P>0.05);治疗后,观察组CRP、IL-6、TNF-α水平低于对照组,差异有统计学意义(P<0.05)。结论自拟益脾清肺汤治疗支气管扩张疗效显著,有利于降低炎性因子的表达,促进患者健康恢复。
Objective To explore the clinical effects of a self-made decoction and its effects on inflammatory factor content in the treatment of bronchiectasis. Methods 94 cases of bronchiectasis who were treated in Jilin Academy of Traditional Chinese Medicine from March 2016 to August 2018 were selected for study. They were randomly divided into a control group(n=47) and an observation group(n=47). Conventional Western medical treatment was adopted in the control group while a self-made decoction used to invigorate spleen and clear away lung heat was adopted in the observation group based on conventional Western medical treatment. Then the clinical effects and inflammatory factor levels were compared between the two groups. Results The overall response rate of clinical treatment in the control group was 82.98%(39/47) while it was 95.74%(45/47) in the observation group. The difference was statistically significant(P<0.05). There was no significant difference in the levels of CRP, IL-6 and TNF-α between the two groups before treatment(P> 0.05). However, these levels in the observation group were lower than those in the control group after treatment and the difference was statistically significant(P<0.05). Conclusion The self-made decoction has significant effects in the treatment of bronchiectasis. It helps to reduce the contents of inflammatory factors and promote recovery of the patients.
Objective To explore the clinical effects of a self-made decoction and its effects on inflammatory factor content in the treatment of bronchiectasis. Methods 94 cases of bronchiectasis who were treated in Jilin Academy of Traditional Chinese Medicine from March 2016 to August 2018 were selected for study. They were randomly divided into a control group(n=47) and an observation group(n=47). Conventional Western medical treatment was adopted in the control group while a self-made decoction used to invigorate spleen and clear away lung heat was adopted in the observation group based on conventional Western medical treatment. Then the clinical effects and inflammatory factor levels were compared between the two groups. Results The overall response rate of clinical treatment in the control group was 82.98%(39/47) while it was 95.74%(45/47) in the observation group. The difference was statistically significant(P<0.05). There was no significant difference in the levels of CRP, IL-6 and TNF-α between the two groups before treatment(P> 0.05). However, these levels in the observation group were lower than those in the control group after treatment and the difference was statistically significant(P<0.05). Conclusion The self-made decoction has significant effects in the treatment of bronchiectasis. It helps to reduce the contents of inflammatory factors and promote recovery of the patients.
引文
[1]訾素娜,黄海茵.中医辨证治疗支气管扩张症的研究现状与探析[J].世界科学技术-中医药现代化,2017,12(11):213-214.
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[3]陈明,马家驹,周继朴.温阳健脾化痰汤对支气管扩张缓解期患者临床疗效及生活质量的影响[J].中医药导报,2017,20(15):93-95.
[4]余汉霞,蔡德栋.自拟益脾清肺汤对支气管扩张的治疗作用及对炎性因子含量的影响[J].中医药学报,2017,45(3):123-125.
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[6]仕丽,王檀,胡少丹,等.平肝清肺汤治疗支气管扩张(肝阳上亢证)临床观察[J].吉林中医药,2012,32(8):801-802.
[7]吕敬江,吕湘南.养阴清肺汤治疗支气管扩张咯血25例小结[J].湖南中医杂志,1994(s1):35-36.
[2]孙辉,苏奕亮.中西医结合治疗支气管扩张症稳定期患者的临床疗效[J].中国全科医学,2014,35(33):4000-4002.
[3]陈明,马家驹,周继朴.温阳健脾化痰汤对支气管扩张缓解期患者临床疗效及生活质量的影响[J].中医药导报,2017,20(15):93-95.
[4]余汉霞,蔡德栋.自拟益脾清肺汤对支气管扩张的治疗作用及对炎性因子含量的影响[J].中医药学报,2017,45(3):123-125.
[5]徐波,张静,樊长征,等.苗青自拟补中柴前连梅汤治疗支气管扩张症稳定期经验[J].中华中医药杂志,2017,15(1):163-165.
[6]仕丽,王檀,胡少丹,等.平肝清肺汤治疗支气管扩张(肝阳上亢证)临床观察[J].吉林中医药,2012,32(8):801-802.
[7]吕敬江,吕湘南.养阴清肺汤治疗支气管扩张咯血25例小结[J].湖南中医杂志,1994(s1):35-36.