DNA发夹结构自组装信号放大策略应用的研究进展
|
摘要
DNA发夹结构自组装因具有无酶参与、等温以及识别序列能力强等优点,在生物分子和金属离子检测方面展现了良好的发展前景。该文梳理了DNA发夹结构自组装信号放大策略的类型,综述了近年来该策略在致病菌、核酸肿瘤标记物、蛋白质、无机金属离子,以及生物小分子检测中应用的研究进展,并对其未来发展趋势进行了展望,旨在为基于DNA发夹结构自组装检测生物分子提供一定的参考。
Hairpin structured DNA self-assembly is widely used in the detection on biomolecules as it possesses the advantages of enzyme-free,isothermal and high recognition rate,etc. In this paper,the types of DNA self-assembly and its application in the detection of foodborne pathogens,tumor marker,protein,inorganic metal and small biomolecules are briefly summarized,and its future developments are also discussed so as to provide a reference for the study of biomolecules based on hairpin structured DNA self-assembly.
Hairpin structured DNA self-assembly is widely used in the detection on biomolecules as it possesses the advantages of enzyme-free,isothermal and high recognition rate,etc. In this paper,the types of DNA self-assembly and its application in the detection of foodborne pathogens,tumor marker,protein,inorganic metal and small biomolecules are briefly summarized,and its future developments are also discussed so as to provide a reference for the study of biomolecules based on hairpin structured DNA self-assembly.
引文
[1]Su C,Ji X H,He Z K.J.Anal.Sci.(苏晨,吉邢虎,何治柯.分析科学学报),2016,32(2):273-281.
[2]Gerasimova Y V,Kolpashchikov D M.Chem.Soc.Rev.,2014,43(17):6405-6438.
[3]Zhou X M,Xing D.Acta Laser Biol.Sin.(周小明,邢达.激光生物学报),2011,20(6):718-722.
[4]Fang Z Y,Wu W,Lu X W,Zeng L W.Biosens.Bioelecrton.,2014,56:192-197.
[5]Wong J K F,Yip S P,Lee T M H.Small,2014,10(8):1495-1499.
[6]Zhu X,Xu H F,Zheng H Y,Yang G D,Lin Z Y,Qiu B,Guo L H,Chi Y W,Chen G N.Chem.Commun.,2013,49(86):10115-10117.
[7]Wang W,Bao T,Zeng X,Xiong H Y,Wen W,Zhang X H,Wang S F.Biosens.Bioelectron.,2017,91:183-189.
[8]Zhao J,Hu S S,Cao Y,Zhang B,Li G X.Biosens.Bioelectron.,2015,66:327-331.
[9]Dirks R M,Pierce N A.P.Natl.Acad.Sci.USA,2004,101(43):15275-15278.
[10]Wu Z W.Study on the New Colorimetric DNA Detection Assay Based on DNA Self-assembly.Qingdao:Qingdao University of Science and Technology(吴志伟.基于DNA自组装的纳米金比色检测DNA新方法研究.青岛:青岛科技大学),2015.
[11]Wang F A,Lu C H,Willner I.Chem.Rev.,2014,114(5):2881-2941.
[12]Yin P,Choi H M T,Calvert C R,Pierce N A.Nature,2008,451(7176):318-322.
[13]Zhang D Y,Turberfield A J,Yurke B,Winfree E.Science,2007,318(5853):1121-1125.
[14]Guo Q,Han J J,Shan S,Liu D F,Wu S S,Xiong Y H,Lai W H.Biosens.Bioelectron.,2016,86:990-995.
[15]Chen W H,Yan Y R,Zhang Y,Zhang X M,Yin Y B,Ding S J.Sci.Rep.,2015,5:11190.
[16]Ying N,Ju C J,Li Z Y,Liu W S,Wan J Y.Talanta,2017,164:432-438.
[17]Ma C P,Wu Z W,Wang W S,Jiang Q Q,Shi C.J.Mater.Chem.B,2015,3(14):2853-2857.
[18]Zhai Q,He Y,Li X L,Guo J,Li S Q,Yi G.J.Electroanal.Chem.,2015,758:20-25.
[19]Zhang Y,Yan Y R,Chen W H,Cheng W,Li S Q,Ding X J,Li D D,Wang H,Ju H X,Ding S J.Biosens.Bioelectron.,2015,68:343-349.
[20]Wei Y L,Zhou W J,Li X,Chai Y Q,Yuan R,Xiang Y.Biosens.Bioelectron.,2016,77:416-420.
[21]Yang L,Liu C H,Ren W,Li Z P.ACS Appl.Mater.Int.,2012,4(12):6450-6453.
[22]Yu Y Q,Wang J P,Zhao M,Hong L R,Chai Y Q,Yuan R,Zhuo Y.Biosens.Bioelectron.,2016,77:442-450.
[23]Wang X Z,Jiang A W,Hou T,Li H Y,Li F.Biosens.Bioelectron.,2015,70:324-329.
[24]Zhang B,Liu B Q,Tang D P,Niessner R,Chen G N,Knopp D.Anal.Chem.,2012,84(12):5392-5399.
[25]Tang Y N,Lin Y W,Yang X L,Wang Z X,Le X C,Li F.Anal.Chem.,2015,87(16):8063-8066.
[26]Zhang Y Y,Wang L H,Wang Y N,Dong Y F.Sensors-Basel,2018,18(7):2179.
[27]Zhao J C,Ma Z F.Biosens.Bioelectron.,2018,102:316-320.
[28]Li Z B,Miao X M,Cheng Z Y,Wang P.Sens.Actuators B,2017,243:731-737.
[29]Huang H H,Yang X H,Wang K M,Wang Q,Guo Q P,Huang J,Liu J B,Song C X.Analyst,2016,141(8):2502-2507.
[30]Li X M,Wang Y,Wang L L,Wei Q L.Chem.Commun.,2014,50(39):5049-5052.
[31]Wang Y H,Jiang L,Leng Q G,Wu Y H,He X X,Wang K M.Biosens.Bioelectron.,2016,77:914-920.
[32]Ge J,Huang Z M,Xi Q,Yu R Q,Jiang J H,Chu X.Chem.Commun.,2014,50(80):11879-11882.
[33]Fu B,Cao J C,Jiang W,Wang L.Biosens.Bioelectron.,2013,44:52-56.
[34]Xu H F,Ye H Z,Zhu X,Chi Y W,Liu X X,Chen G N.Anal.Methods,2014,6(13):4512-4515.
[35]Li X,Xie J Q,Jiang B Y,Yuan R,Xiang Y.ACS Appl.Mater.Int.,2017,9(7):5733-5738.
[36]Chen J H,Zhou X M,Zeng L W.Chem.Commun.,2013,49(10):984-986.
[37]Yu B,Li F L,Zhao T C,Li F,Zhou B Q,Xu H Y.Sens.Actuators B,2018,256:624-631.
[38]Chen H L,Guo M M,Tang H,Wu Z,Tang L J,Yu R Q,Jiang J H.Anal.Methods,2015,7(6):2258-2263.
[39]Wu H,Liu Y L,Wang H Y,Wu J,Zhu F F,Zou P.Biosens.Bioelectron.,2016,81:303-308.
[40]Miao X M,Ning X,Li Z B,Cheng Z Y.Sci.Rep.,2016,6:32358.
[41]Wu J,Fu Z F,Yan F,Ju H X.TRAC-Trend Anal.Chem.,2007,26(7):679-688.
[42]Qin C Y,Wen W,Zhang X H,Gu H S,Wang S F.Chem.Commun.,2015,51(39):8273-8275.
[43]Wen W,Huang J Y,Bao T,Zhou J,Xia H X,Zhang X H,Wang S F,Zhao Y D.Biosens.Bioelectron.,2016,83:142-148.
[44]Yang W T,Zhou X X,Zhao J M,Xu W J.Microchim.Acta,2018,185(2):100.
[45]Lu R J,Li S Q,Fan M H,Wei J J,Liu X.RSC Adv.,2018,8(26):14663-14668.
[46]Bai S L,Wang T,Zhang Z,Sheng S C,Yu W,Xie G M.Sens.Actuators B,2017,239:447-454.
[47]Gao Z Q,Qiu Z L,Lu M H,Shu J,Tang D P.Biosens.Bioelectron.,2017,89:1006-1012.
[48]Sun J W,Jiang W,Zhu J,Li W,Wang L.Biosens.Bioelectron.,2015,70:15-20.
[49]Wang C K,Dong X Y,Liu Q,Wang K.Anal.Chim.Acta,2015,860:83-88.
[50]Zhuang J Y,Fu L B,Xu M D,Zhou Q,Chen G N,Tang D P.Biosens.Bioelectron.,2013,45:52-57.
[51]Huang J H,Gao X,Jia J J,Kim J K,Li Z G.Anal.Chem.,2014,86(6):3209-3215.
[52]Wang Q,Yang X H,Yang X H,Liu P,Wang K M,Huang J,Liu J B,Song C X,Wang J J.Spectrochim.Acta A,2015,136:283-287.
[2]Gerasimova Y V,Kolpashchikov D M.Chem.Soc.Rev.,2014,43(17):6405-6438.
[3]Zhou X M,Xing D.Acta Laser Biol.Sin.(周小明,邢达.激光生物学报),2011,20(6):718-722.
[4]Fang Z Y,Wu W,Lu X W,Zeng L W.Biosens.Bioelecrton.,2014,56:192-197.
[5]Wong J K F,Yip S P,Lee T M H.Small,2014,10(8):1495-1499.
[6]Zhu X,Xu H F,Zheng H Y,Yang G D,Lin Z Y,Qiu B,Guo L H,Chi Y W,Chen G N.Chem.Commun.,2013,49(86):10115-10117.
[7]Wang W,Bao T,Zeng X,Xiong H Y,Wen W,Zhang X H,Wang S F.Biosens.Bioelectron.,2017,91:183-189.
[8]Zhao J,Hu S S,Cao Y,Zhang B,Li G X.Biosens.Bioelectron.,2015,66:327-331.
[9]Dirks R M,Pierce N A.P.Natl.Acad.Sci.USA,2004,101(43):15275-15278.
[10]Wu Z W.Study on the New Colorimetric DNA Detection Assay Based on DNA Self-assembly.Qingdao:Qingdao University of Science and Technology(吴志伟.基于DNA自组装的纳米金比色检测DNA新方法研究.青岛:青岛科技大学),2015.
[11]Wang F A,Lu C H,Willner I.Chem.Rev.,2014,114(5):2881-2941.
[12]Yin P,Choi H M T,Calvert C R,Pierce N A.Nature,2008,451(7176):318-322.
[13]Zhang D Y,Turberfield A J,Yurke B,Winfree E.Science,2007,318(5853):1121-1125.
[14]Guo Q,Han J J,Shan S,Liu D F,Wu S S,Xiong Y H,Lai W H.Biosens.Bioelectron.,2016,86:990-995.
[15]Chen W H,Yan Y R,Zhang Y,Zhang X M,Yin Y B,Ding S J.Sci.Rep.,2015,5:11190.
[16]Ying N,Ju C J,Li Z Y,Liu W S,Wan J Y.Talanta,2017,164:432-438.
[17]Ma C P,Wu Z W,Wang W S,Jiang Q Q,Shi C.J.Mater.Chem.B,2015,3(14):2853-2857.
[18]Zhai Q,He Y,Li X L,Guo J,Li S Q,Yi G.J.Electroanal.Chem.,2015,758:20-25.
[19]Zhang Y,Yan Y R,Chen W H,Cheng W,Li S Q,Ding X J,Li D D,Wang H,Ju H X,Ding S J.Biosens.Bioelectron.,2015,68:343-349.
[20]Wei Y L,Zhou W J,Li X,Chai Y Q,Yuan R,Xiang Y.Biosens.Bioelectron.,2016,77:416-420.
[21]Yang L,Liu C H,Ren W,Li Z P.ACS Appl.Mater.Int.,2012,4(12):6450-6453.
[22]Yu Y Q,Wang J P,Zhao M,Hong L R,Chai Y Q,Yuan R,Zhuo Y.Biosens.Bioelectron.,2016,77:442-450.
[23]Wang X Z,Jiang A W,Hou T,Li H Y,Li F.Biosens.Bioelectron.,2015,70:324-329.
[24]Zhang B,Liu B Q,Tang D P,Niessner R,Chen G N,Knopp D.Anal.Chem.,2012,84(12):5392-5399.
[25]Tang Y N,Lin Y W,Yang X L,Wang Z X,Le X C,Li F.Anal.Chem.,2015,87(16):8063-8066.
[26]Zhang Y Y,Wang L H,Wang Y N,Dong Y F.Sensors-Basel,2018,18(7):2179.
[27]Zhao J C,Ma Z F.Biosens.Bioelectron.,2018,102:316-320.
[28]Li Z B,Miao X M,Cheng Z Y,Wang P.Sens.Actuators B,2017,243:731-737.
[29]Huang H H,Yang X H,Wang K M,Wang Q,Guo Q P,Huang J,Liu J B,Song C X.Analyst,2016,141(8):2502-2507.
[30]Li X M,Wang Y,Wang L L,Wei Q L.Chem.Commun.,2014,50(39):5049-5052.
[31]Wang Y H,Jiang L,Leng Q G,Wu Y H,He X X,Wang K M.Biosens.Bioelectron.,2016,77:914-920.
[32]Ge J,Huang Z M,Xi Q,Yu R Q,Jiang J H,Chu X.Chem.Commun.,2014,50(80):11879-11882.
[33]Fu B,Cao J C,Jiang W,Wang L.Biosens.Bioelectron.,2013,44:52-56.
[34]Xu H F,Ye H Z,Zhu X,Chi Y W,Liu X X,Chen G N.Anal.Methods,2014,6(13):4512-4515.
[35]Li X,Xie J Q,Jiang B Y,Yuan R,Xiang Y.ACS Appl.Mater.Int.,2017,9(7):5733-5738.
[36]Chen J H,Zhou X M,Zeng L W.Chem.Commun.,2013,49(10):984-986.
[37]Yu B,Li F L,Zhao T C,Li F,Zhou B Q,Xu H Y.Sens.Actuators B,2018,256:624-631.
[38]Chen H L,Guo M M,Tang H,Wu Z,Tang L J,Yu R Q,Jiang J H.Anal.Methods,2015,7(6):2258-2263.
[39]Wu H,Liu Y L,Wang H Y,Wu J,Zhu F F,Zou P.Biosens.Bioelectron.,2016,81:303-308.
[40]Miao X M,Ning X,Li Z B,Cheng Z Y.Sci.Rep.,2016,6:32358.
[41]Wu J,Fu Z F,Yan F,Ju H X.TRAC-Trend Anal.Chem.,2007,26(7):679-688.
[42]Qin C Y,Wen W,Zhang X H,Gu H S,Wang S F.Chem.Commun.,2015,51(39):8273-8275.
[43]Wen W,Huang J Y,Bao T,Zhou J,Xia H X,Zhang X H,Wang S F,Zhao Y D.Biosens.Bioelectron.,2016,83:142-148.
[44]Yang W T,Zhou X X,Zhao J M,Xu W J.Microchim.Acta,2018,185(2):100.
[45]Lu R J,Li S Q,Fan M H,Wei J J,Liu X.RSC Adv.,2018,8(26):14663-14668.
[46]Bai S L,Wang T,Zhang Z,Sheng S C,Yu W,Xie G M.Sens.Actuators B,2017,239:447-454.
[47]Gao Z Q,Qiu Z L,Lu M H,Shu J,Tang D P.Biosens.Bioelectron.,2017,89:1006-1012.
[48]Sun J W,Jiang W,Zhu J,Li W,Wang L.Biosens.Bioelectron.,2015,70:15-20.
[49]Wang C K,Dong X Y,Liu Q,Wang K.Anal.Chim.Acta,2015,860:83-88.
[50]Zhuang J Y,Fu L B,Xu M D,Zhou Q,Chen G N,Tang D P.Biosens.Bioelectron.,2013,45:52-57.
[51]Huang J H,Gao X,Jia J J,Kim J K,Li Z G.Anal.Chem.,2014,86(6):3209-3215.
[52]Wang Q,Yang X H,Yang X H,Liu P,Wang K M,Huang J,Liu J B,Song C X,Wang J J.Spectrochim.Acta A,2015,136:283-287.