不育症常用药对探析
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摘要
男性不育症是男科门诊常见的疾病,中医一般认为不育症病机多以肾虚为主,治疗一般采用补肾壮阳的治法。然而,经过长期的临床实践,发现肾虚、肝郁、脾虚、血瘀均为男性不育的主要致病因素,辨证治疗时可根据具体的症状选用数种药对灵活增减以提高临床疗效。补益水火以生精,用熟地黄与鹿茸合用以水火并补,麦冬与枸杞子合用以滋水泻火;养血柔肝以调精,用当归与何首乌合用以养血柔肝,香附与乌药合用以理气解郁;健脾化湿以活精,用生黄芪与生麦芽合用以补中益气,茯苓与白术合用以燥湿化痰。
Male infertility is a common disease in male outpatient clinics. Traditional Chinese medicine generally believes that infertility pathogenesis is mainly caused by kidney deficiency. Treatment is generally based on the treatment of kidney, spleen deficiency and impotence. However, after long-term clinical practice, it is found that kidney deficiency, liver depression, spleen deficiency and blood stasis are the main pathogenic factors of male infertility. In order to improve the effect, several drugs can be used for flexible increase and decrease in syndrome differentiation treatment according to the specitic symptoms. Replenishing water and fire to produce sperm, Lurong and Shudi can be used together for tonifying water and fire, and supplemented with Maidong and Gouqizi for nourshing water and clearing heat; nourishing blood and softening the liver to regulate fineness, can be used with Danggui to nourish blood and soft liver, Xiangfu and Wuyao are used together for relieving qi stagnation, invigorating spleen for eliminating dampness for activating sperm, Shenghuangqi and Shengmaiya are used together for invigorating spleen and replenishing qi, Fuling and Baizhu are used together for eliminating dampness and phlegm.
Male infertility is a common disease in male outpatient clinics. Traditional Chinese medicine generally believes that infertility pathogenesis is mainly caused by kidney deficiency. Treatment is generally based on the treatment of kidney, spleen deficiency and impotence. However, after long-term clinical practice, it is found that kidney deficiency, liver depression, spleen deficiency and blood stasis are the main pathogenic factors of male infertility. In order to improve the effect, several drugs can be used for flexible increase and decrease in syndrome differentiation treatment according to the specitic symptoms. Replenishing water and fire to produce sperm, Lurong and Shudi can be used together for tonifying water and fire, and supplemented with Maidong and Gouqizi for nourshing water and clearing heat; nourishing blood and softening the liver to regulate fineness, can be used with Danggui to nourish blood and soft liver, Xiangfu and Wuyao are used together for relieving qi stagnation, invigorating spleen for eliminating dampness for activating sperm, Shenghuangqi and Shengmaiya are used together for invigorating spleen and replenishing qi, Fuling and Baizhu are used together for eliminating dampness and phlegm.
引文
[1] 王旭昀,张宏,孙占学,等.中医药治疗男子不育症研究进展[J].中华中医药学刊,2015,33 (4) :975-977.
[2] 杨洋,兰永连,李颖,等.男性不育影响因素的调查[J].中国优生与遗传杂志,2014,22(12):118-119.
[3] 赵玉,欧阳斌,耿强.男性不育症动物模型的国外研究进展[J].中国计划生育学杂志,2014,22(11):781-785.
[4] 曾杰,许明贺,焦薇薇,等.从健脾补肾立法论治男性不育症的辨证思路[J].中华中医药杂志,2018,33(1):182-184.
[5] 刘祺,杨希,曹继刚.气郁体质与男性不育[J].河南中医,2016,36(6):1071-1073.
[6] 刘洋,王彬,莫旭威,等.李海松教授从脾、肾、肝论治男性精液不液化不育的学术思想[J].中国性科学,2015,24(4):84-86.
[7] 王继升,代恒恒,王彬,等.男性不育症与虚、滞、痰、瘀的关系思考[J].中国性科学,2017,26(10):87-89.
[8] 陈怡红,李海文,沙伟玲,等.中药治疗男性不育患者精液分析[J].内蒙古中医药,2016,35(6):24-25.
[9] 陶弘景.名医别录[M].尚志钧,辑校.北京:人民卫生出版社,1986:21.
[10] 周春宇,马凰富,王彬,等.男性不育症中医辨治思路[J].中医杂志,2016,57(13):1105-1108.
[11] 杨彬,祁玉霞,李宏军,等.男性不育患者中勃起功能状况的初步研究 [J].生殖医学杂志,2016,25(9):799-804.
[12] 马建雄,王彬,党进,等.男性不育症患者勃起功能状况与精神心理状态的相关性研究 [J].中华男科学杂志,2017,23(7):609-614.
[13] 李时珍.本草纲目[M].王育杰,整理.北京:人民卫生出版社,2005:268.
[14] 张秉成.本草便读[M].张效霞,校注.北京:学苑出版社,2010.
[15] 姜永辉,孔伟,刘燕,等.脾胃与男性不育探骊[J].中医药学报,2016,44(4):48-50.
[16] 付晓燕,管庆波.肥胖相关并发症研究进展[J].辽宁中医药大学学报,2017,1(1):105-108.
[17] 汪昂.本草备要[M].谢观,董丰培,评校.重庆:重庆大学出版社,1996:195.
[18] 汪程鹏,施剑飞,宋明芬,等.生麦芽对利培酮所致雌性大鼠高泌乳素血症的抑制作用[J].中国临床药理学杂志,2018,34(9):1092-1094.
[19] 张山雷.本草正义[M].程东旗,点校.福州:福建科学技术出版社,2006:24.
[20] 张晓娟,左冬冬.白术化学成分及药理作用研究新进展[J].中医药信息,2018,35(6):101-106.
[21] 赵英伟,袁重胜,孙萌,等.肥胖及皮质醇、雌激素等因素与2型糖尿病的关系调查[J].苏州大学学报(医学版),2007,27(5):787-789.
[2] 杨洋,兰永连,李颖,等.男性不育影响因素的调查[J].中国优生与遗传杂志,2014,22(12):118-119.
[3] 赵玉,欧阳斌,耿强.男性不育症动物模型的国外研究进展[J].中国计划生育学杂志,2014,22(11):781-785.
[4] 曾杰,许明贺,焦薇薇,等.从健脾补肾立法论治男性不育症的辨证思路[J].中华中医药杂志,2018,33(1):182-184.
[5] 刘祺,杨希,曹继刚.气郁体质与男性不育[J].河南中医,2016,36(6):1071-1073.
[6] 刘洋,王彬,莫旭威,等.李海松教授从脾、肾、肝论治男性精液不液化不育的学术思想[J].中国性科学,2015,24(4):84-86.
[7] 王继升,代恒恒,王彬,等.男性不育症与虚、滞、痰、瘀的关系思考[J].中国性科学,2017,26(10):87-89.
[8] 陈怡红,李海文,沙伟玲,等.中药治疗男性不育患者精液分析[J].内蒙古中医药,2016,35(6):24-25.
[9] 陶弘景.名医别录[M].尚志钧,辑校.北京:人民卫生出版社,1986:21.
[10] 周春宇,马凰富,王彬,等.男性不育症中医辨治思路[J].中医杂志,2016,57(13):1105-1108.
[11] 杨彬,祁玉霞,李宏军,等.男性不育患者中勃起功能状况的初步研究 [J].生殖医学杂志,2016,25(9):799-804.
[12] 马建雄,王彬,党进,等.男性不育症患者勃起功能状况与精神心理状态的相关性研究 [J].中华男科学杂志,2017,23(7):609-614.
[13] 李时珍.本草纲目[M].王育杰,整理.北京:人民卫生出版社,2005:268.
[14] 张秉成.本草便读[M].张效霞,校注.北京:学苑出版社,2010.
[15] 姜永辉,孔伟,刘燕,等.脾胃与男性不育探骊[J].中医药学报,2016,44(4):48-50.
[16] 付晓燕,管庆波.肥胖相关并发症研究进展[J].辽宁中医药大学学报,2017,1(1):105-108.
[17] 汪昂.本草备要[M].谢观,董丰培,评校.重庆:重庆大学出版社,1996:195.
[18] 汪程鹏,施剑飞,宋明芬,等.生麦芽对利培酮所致雌性大鼠高泌乳素血症的抑制作用[J].中国临床药理学杂志,2018,34(9):1092-1094.
[19] 张山雷.本草正义[M].程东旗,点校.福州:福建科学技术出版社,2006:24.
[20] 张晓娟,左冬冬.白术化学成分及药理作用研究新进展[J].中医药信息,2018,35(6):101-106.
[21] 赵英伟,袁重胜,孙萌,等.肥胖及皮质醇、雌激素等因素与2型糖尿病的关系调查[J].苏州大学学报(医学版),2007,27(5):787-789.