高坡猪PRKAA1基因多态性对肉质性状的影响
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摘要
以腺苷单磷酸活化蛋白激酶α1(PRKAA1)基因作为候选基因,对50头10月龄的高坡猪PRKAA1基因序列进行PCR扩增,采用PCR扩增产物直接测序方法对该基因的SNP位点进行筛选,同时对不同基因型与肉质性状关联分析。结果表明,在高坡猪PRKAA1基因的序列中发现3个SNPs,分别为g.12988 T
引文
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[13]宋娇,付睿琦,李颖颖,等.肉鸡PRKAA基因表达与My HC基因表达和肌内脂肪沉积关系的研究[J].中国畜牧杂志,2012,48(23):10-13.
[2]Loverso F,Carnio S,Vainshtein A,et al.Autophagy is not required to sustain exercise and PRKAA1/AMPK activity but is important to prevent mitochondrial damage during physical activity[J].Autophagy,2014,10(11):1883-1894.
[3]耿凤豪,张鹏,董玲,等.AMPK-能量代谢感受器与可激活AMPK相关的药物研究进展[J].心脏杂志,2014,26(1):97-100.
[4]Lee S J,Kang B W,Chae Y S,et al.Genetic variations in STK11,PRKAA1,and TSC1 associated with prognosis for patients with colorectal cancer[J].Annals of Surgical Oncology,2014,21(S4):634-639.
[5]Yuan J,Zhang Y,Yan F T,et al.Association of PRKAA1 gene polymorphisms with chronic hepatitis B virus infection in Chinese Han population[J].Brazilian Journal of Infectious Diseases,2016,20(6):564-568.
[6]孙成娟,许厚强,陈伟,等.贵州从江香猪Fox O4、PRKAA1基因在不同组织中的表达分析[J].基因组学与应用生物学,2017,35(3):841-846.
[7]Kim Y D,Yim D H,Eom S Y,et al.Risk of gastric cancer is associated with PRKAA1 gene polymorphisms in Koreans[J].World Journal of Gastroenterology,2014,20(26):8592-8598.
[8]张依裕,胡尚,周训军.高坡猪种质资源特性初步研究[J].贵州农业科学,2008,36(5):115-117.
[9]Tong J,Zhu M J,Underwood K R,et al.AMP-activated protein kinase and adipogenesis in sheep fetal skeletal muscle and 3T3-L1cells[J].Journal of Animal Science,2008,86(6):1296-1305.
[10]任阳.饱和与不饱和脂肪酸对猪肌纤维组成的影响及其AMPK途径研究[D].杭州:浙江大学,2014:19-40.
[11]Zhong W,Xie Y,Abdallah M,et al.Cellular stress causes reversible,PRKAA1/2-,and proteasome-dependent ID2 protein loss in trophoblast stem cells[J].Reproduction,2010,140(6):921-930.
[12]田万强.牛AMPK家族7个基因SNP检测及其与生长和肉质性状的关联分析[D].杨凌:西北农林科技大学,2013:20-45.
[13]宋娇,付睿琦,李颖颖,等.肉鸡PRKAA基因表达与My HC基因表达和肌内脂肪沉积关系的研究[J].中国畜牧杂志,2012,48(23):10-13.
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