2016-2017年达州市布鲁菌病高危人群血清学筛查结果分析
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摘要
目的分析达州市布鲁菌病(以下简称"布病")高危人群的感染状况,为今后布病防治工作奠定基础。方法按照国家标准对布病高危人群进行血清学检测并统计分析。结果共检测高危人群1 336人,虎红平板凝集试验(RBPT)初筛阳性51份,阳性率3. 82%;试管凝集试验(SAT)确证阳性18份,阳性率1. 35%。性别、地区分布无统计学意义(P>0. 05),前两年有人间布病病例报告地区的初筛总阳性率5. 72%(34/594)明显高于尚无病例报告地区2. 29%(17/742),两者差异有统计学意义(χ2=9. 78,P=0. 001 8)。确证总阳性率1. 52%(9/594)虽高于尚无病例报告地区1. 21%(9/742),但差异无统计学意义(χ2=0. 22,P=0. 64)。与有病例报告地区接壤的大竹县确证阳性数最多。高危人群以中年人居多。职业分布有统计学意义(χ2=6. 94,P<0. 05),养殖户人群阳性率最高。结论达州市存在潜在的布病暴发风险,且有蔓延的趋势。监测工作要加强标本采集的质量控制,同时,因地制宜加强本地中青年畜牧养殖人群的健康教育,增强其自我保护和检疫意识。
Objective Analysis on the infection situation of brucellosis in high risk population in Dazhou city,and to lay the foundation for the future prevention and control of brucellosis. Methods In accordance with the national standards of brucellosis,serological testing was carried out to the high risk group and the results was analyzed statistically. Results A total of 1 336 people were tested as high risk group. About 51 positive samples were detected by RBPT,and the positive rate was 3. 82%. The 18 positive samples were confirmed by SAT,the positive rate was 1. 35%. Gender and area distribution was not statistically significant( P > 0. 05). Total screening positive rate was 5. 72%( 34/594) in the area of brucellosis reported cases in the previous two years,which was significantly higher than that of the no reported cases( 2. 29%,17/742),the difference was statistically significant( χ2= 9. 78,P = 0. 001 8). The total positive rate of confirm was 1. 52%( 9/594),although it was higher than that of no reported cases 1. 21%( 9/742),but the difference was not statistically significant( χ2= 0. 22,P = 0. 64). The confirmed positive number of case in Dazhu county which is bordered by the reported areas was the most. The high risk group was at middle-aged,occupational distribution was statistically significant( χ2= 6. 94,P<0. 05),and the farmer was the highest positive rate. Conclusion There is a potential risk of outbreaks of brucellosis in Dazhou city and has a tendency to spread. The quality control of specimen collection should be strengthened in monitoring work,and to strengthen the health education and propaganda on local youth population of livestock breeding in line with local conditions,so as to enhance their awareness of self-protection and quarantine.
Objective Analysis on the infection situation of brucellosis in high risk population in Dazhou city,and to lay the foundation for the future prevention and control of brucellosis. Methods In accordance with the national standards of brucellosis,serological testing was carried out to the high risk group and the results was analyzed statistically. Results A total of 1 336 people were tested as high risk group. About 51 positive samples were detected by RBPT,and the positive rate was 3. 82%. The 18 positive samples were confirmed by SAT,the positive rate was 1. 35%. Gender and area distribution was not statistically significant( P > 0. 05). Total screening positive rate was 5. 72%( 34/594) in the area of brucellosis reported cases in the previous two years,which was significantly higher than that of the no reported cases( 2. 29%,17/742),the difference was statistically significant( χ2= 9. 78,P = 0. 001 8). The total positive rate of confirm was 1. 52%( 9/594),although it was higher than that of no reported cases 1. 21%( 9/742),but the difference was not statistically significant( χ2= 0. 22,P = 0. 64). The confirmed positive number of case in Dazhu county which is bordered by the reported areas was the most. The high risk group was at middle-aged,occupational distribution was statistically significant( χ2= 6. 94,P<0. 05),and the farmer was the highest positive rate. Conclusion There is a potential risk of outbreaks of brucellosis in Dazhou city and has a tendency to spread. The quality control of specimen collection should be strengthened in monitoring work,and to strengthen the health education and propaganda on local youth population of livestock breeding in line with local conditions,so as to enhance their awareness of self-protection and quarantine.
引文
[1]石惠惠,陈平,田安宁.达州市1起布鲁氏菌病的流行病学调查[J].现代预防医学,2015,42(12):2132-2133,2137.
[2]WS269-2007布鲁氏菌病诊断标准[S]. 2007.
[3]肖东楼.布鲁氏菌病防治手册[M].北京:人民卫生出版社,2008:45.
[4]罗学东,王轶,王雨,等. 2014年平顶山市布病高危人群血清学筛查结果分析[J].现代预防医学,2015,42(16):3031-3032,3053.
[5]苏良,欧新华,张如胜,等.虎红平板凝集试验检测人血浆布氏菌抗体干扰来源分析及处理对策[J].现代预防医学,2014,41(24):4486-4488,4497.
[6]周敬祝,陈贵春,王定明,等. 2008-2012年贵州省人间布病监测结果分析[J].现代预防医学,2015,42(13):2432-2433,2463.
[7]韩菲,张慧霞,赵永年,等.新疆兵团高危人群的布鲁氏菌病流行现状分析[J].现代预防医学,2017,44(4):581-583,604.
[8]徐向华,张巧红,俎炳灿,等. 2014年许昌市人间布病监测结果分析[J].现代预防医学,2016,43(10):1894-1896,1906.
[9]许华茹,徐淑慧,隋庆梅. 2011-2015年济南市人间布鲁氏菌病监测资料分析[J].现代预防医学,2017,44(7):1312-1315.
[10]胡桂英,马丽,徐立青,等.三江源地区布病血清流行病学调查研究[J].现代预防医学,2015,42(5):769-771.
[11]杨辉,王彭,罗晓芸,等.云南巍山县首起布鲁氏菌病疫情调查处置分析[J].热带病与寄生虫学,2016,14(3):168-169,171.
[12]邓乐,温志立,李林涛,等.江西省布鲁氏菌病病例临床特征及治疗分析[J].中国媒介生物学及控制杂志,2017,28(5):516-516.
[13]木合塔尔·艾山,何海波,邰新平,等.新疆2013年人间布鲁氏菌病监测结果及疫情分析[J].中国媒介生物学及控制杂志,2015,26(1):86-88.
[14]廖伟斌,孙建国,于国伟,等.中国大陆2006-2012年人和牲畜布鲁氏菌病空间分布特征及相关性[J].中国公共卫生,2015,31(10):1289-1293.
[2]WS269-2007布鲁氏菌病诊断标准[S]. 2007.
[3]肖东楼.布鲁氏菌病防治手册[M].北京:人民卫生出版社,2008:45.
[4]罗学东,王轶,王雨,等. 2014年平顶山市布病高危人群血清学筛查结果分析[J].现代预防医学,2015,42(16):3031-3032,3053.
[5]苏良,欧新华,张如胜,等.虎红平板凝集试验检测人血浆布氏菌抗体干扰来源分析及处理对策[J].现代预防医学,2014,41(24):4486-4488,4497.
[6]周敬祝,陈贵春,王定明,等. 2008-2012年贵州省人间布病监测结果分析[J].现代预防医学,2015,42(13):2432-2433,2463.
[7]韩菲,张慧霞,赵永年,等.新疆兵团高危人群的布鲁氏菌病流行现状分析[J].现代预防医学,2017,44(4):581-583,604.
[8]徐向华,张巧红,俎炳灿,等. 2014年许昌市人间布病监测结果分析[J].现代预防医学,2016,43(10):1894-1896,1906.
[9]许华茹,徐淑慧,隋庆梅. 2011-2015年济南市人间布鲁氏菌病监测资料分析[J].现代预防医学,2017,44(7):1312-1315.
[10]胡桂英,马丽,徐立青,等.三江源地区布病血清流行病学调查研究[J].现代预防医学,2015,42(5):769-771.
[11]杨辉,王彭,罗晓芸,等.云南巍山县首起布鲁氏菌病疫情调查处置分析[J].热带病与寄生虫学,2016,14(3):168-169,171.
[12]邓乐,温志立,李林涛,等.江西省布鲁氏菌病病例临床特征及治疗分析[J].中国媒介生物学及控制杂志,2017,28(5):516-516.
[13]木合塔尔·艾山,何海波,邰新平,等.新疆2013年人间布鲁氏菌病监测结果及疫情分析[J].中国媒介生物学及控制杂志,2015,26(1):86-88.
[14]廖伟斌,孙建国,于国伟,等.中国大陆2006-2012年人和牲畜布鲁氏菌病空间分布特征及相关性[J].中国公共卫生,2015,31(10):1289-1293.