中西医结合治疗毛细支气管炎研究进展
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摘要
对于小儿毛细支气管炎,西医多采用免疫预防治疗、支持治疗和药物治疗三种。支持治疗主要有:氧疗、吸痰、物理治疗、补液及高渗盐水雾化等;药物治疗主要包括了支气管扩张剂、肾上腺素、糖皮质激素、白三烯受体拮抗剂、抗病毒及抗生素等;免疫预防治疗包括静脉注射免疫球蛋白与帕利珠单抗等;中医多采用辨证论治、中成药口服、中药静脉制剂、中药雾化吸入、穴位贴敷及中药灌肠等疗法,但缺少单独的中医治法临床研究,临床方面多以西医常规治疗联合中医药治法控制病情,并且取得了较好的临床疗效。尽管对毛细支气管炎的治疗已经取得很大的进展,多种治疗方案的应用也提高了治愈率,但仍缺少一套完整的中西医结合预防与治疗标准。
For infantile capillary bronchitis,immunoprophylaxis,supportive therapy and drug therapy are often adopted in western medicine. Supportive therapy includes: oxygen therapy,sputum suction,physiotherapy,fluid infusion,hypertonic saline,etc. Drug therapy mainly includes bronchial vasodilator,epinephrine,glucocorticoid,leukotriene receptor antagonist,antiviral drugs and antibiotics. Immunoprophylaxis involves intravenous injection of immunoglobulin and palivizumab. TCM therapy mainly includes syndrome differentiation and treatment,oral administration of Chinese patent medicine,intravenous preparation of Chinese medicine,aerosol inhalation of Chinese medicine,acupoint plastering therapy and Chinese medicine enema,but there are insufficient clinical researches on single use of TCM therapy. Combination of conventional western medicine therapy with Chinese medicine is mostly used to control the disease condition and achieves good clinical therapeutic effects. Despite that great progress has been made in the treatment of capillary bronchitis and the application of multiple treatment schemes has enhanced the curative rate,a complete set of criteria for the prevention and the treatment by integrated Chinese and western medicine is still lacking.
For infantile capillary bronchitis,immunoprophylaxis,supportive therapy and drug therapy are often adopted in western medicine. Supportive therapy includes: oxygen therapy,sputum suction,physiotherapy,fluid infusion,hypertonic saline,etc. Drug therapy mainly includes bronchial vasodilator,epinephrine,glucocorticoid,leukotriene receptor antagonist,antiviral drugs and antibiotics. Immunoprophylaxis involves intravenous injection of immunoglobulin and palivizumab. TCM therapy mainly includes syndrome differentiation and treatment,oral administration of Chinese patent medicine,intravenous preparation of Chinese medicine,aerosol inhalation of Chinese medicine,acupoint plastering therapy and Chinese medicine enema,but there are insufficient clinical researches on single use of TCM therapy. Combination of conventional western medicine therapy with Chinese medicine is mostly used to control the disease condition and achieves good clinical therapeutic effects. Despite that great progress has been made in the treatment of capillary bronchitis and the application of multiple treatment schemes has enhanced the curative rate,a complete set of criteria for the prevention and the treatment by integrated Chinese and western medicine is still lacking.
引文
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[21]刘娟.涤痰平喘饮治疗毛细支气管炎52例[J].河南中医,2010,30(4):379-380.
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[31]洪丽君,刘克新,殷齐辉.加味三子养亲汤保留灌肠佐治毛细支气管炎急性发作疗效观察[J].中国中西医结合儿科学,2015,7(3):266-267.
[32]刘飞霞,黄如红,毕美芬,等.中药内服加灌肠治疗毛细支气管炎46例临床观察[J].中国中医药科技,2011,18(3):253-254.
[2]杨占秋,余宏.临床病毒学[M].北京:中国医药科技出版社,2000:195-197.
[3]陈皆兵,罗汉清.毛细支气管炎中西医治疗研究进展[J].中国现代医生,2012,50(24):28-29.
[4]张赛,程燕.程燕教授治疗毛细支气管炎经验[J].四川中医,2015,33(4):9-11.
[5]陈婷,刘恩梅.急性毛细支气管炎临床治疗进展[J].儿科药学杂志,2015,21(7):55-58.
[6]廖景文.支气管扩张剂氧驱动雾化吸入辅助治疗小婴儿毛细支气管炎疗效比较[J].临床医学,2014,34(8):39-40.
[7]赵会平,孙华.肾上腺素雾化吸入治疗毛细支气管炎的疗效观察[J].吉林医学,2013,34(17):3378-3379.
[8]陈凯.肾上腺素与沙丁胺醇雾化吸入治疗婴儿毛细支气管炎疗效比较[J].实用儿科临床杂志,2009,24(13):1037-1038.
[9]陈妍妍,石太新.糖皮质激素在毛细支气管炎治疗中的应用[J].中国现代药物应用,2014,8(18):1-3.
[10]蒋晓红,张思华.糖皮质激素在毛细支气管炎治疗中的应用分析[J].世界最新医学信息文摘,2015,15(17):21-23.
[11]马晓晖,崔振泽,黄燕.毛细支气管炎与白三烯受体拮抗剂[J].医学综述,2011,17(15):2249-2252.
[12]罗玉.白三烯受体拮抗剂(孟鲁司特钠)治疗小儿毛细支气管炎疗效观察[J].中外妇儿健康,2011,19(7):26.
[13]宁建英,刘莹,陈波.利巴韦林雾化吸入治疗毛细支气管炎的临床观察[J].临床和实验医学杂志,2013,12(13):1010-1011,1014.
[14]宁建英.毛细支气管炎抗生素合理应用的探讨[J].农垦医学,2012,34(4):300-302.
[15]贲洋.大环内酯类抗生素佐治毛细支气管炎临床分析[J].中国当代医药,2011,18(28):54-56.
[16]赵振元,刘再亮,刘先玲.宣肺降逆平喘法治疗129例毛细支气管炎疗效观察[J].中国中西医结合儿科学,2011,3(3):262-263.
[17]冯丹瑛.加味小青龙汤治疗小儿毛细支气管炎(风寒闭肺证)临床疗效观察[D].长沙:湖南中医药大学,2014:31-32.
[18]朱惠琴,孙莉.小青龙汤加味联合小剂量甲泼尼龙琥珀酸钠治疗小儿毛细支气管炎40例[J].河南中医,2015,35(6):1221-1223.
[19]金晓颖.中西医结合治疗婴幼儿毛细支气管炎63例疗效观察[J].中国中西医结合儿科学,2011,3(5):417-418.
[20]樊晋萍.清肺化痰活血解毒法治疗毛细支气管炎痰热闭肺证临床疗效观察[D].南京:南京中医药大学,2010:31-32.
[21]刘娟.涤痰平喘饮治疗毛细支气管炎52例[J].河南中医,2010,30(4):379-380.
[22]段哲.小儿麻甘颗粒治疗风热和痰热闭肺毛细支气管炎疗效观察[D].广州:广州中医药大学,2013:14-15.
[23]于瑞亮,刘桂红,张华.中西医结合治疗小儿毛细支气管炎的疗效观察[J].中国实用医药,2012,7(17):155-157.
[24]唐兴.小儿肺热咳喘液治疗毛细支气管炎30例[J].河南中医,2013,33(9):1500-1501.
[25]张军丽,高金星,余饮春.中西医结合治疗毛细支气管炎的临床疗效观察[J].现代中西医结合杂志,2013,22(20):2223-2224.
[26]王彩霞,宋业华.生脉注射液治疗毛细支气管炎的临床分析[J].中国社区医师:医学专业,2010,12(10):77.
[27]韩丽婷.双黄连吸入治疗毛细支气管炎疗效观察[J].黑龙江医学,2008,27(10):777-778.
[28]魏春根.中药雾化治疗小儿毛细支气管炎45例[J].中国中医药现代远程教育,2013,11(23):51.
[29]董朝,陆宏进,时骏英.中药穴位外治法辅助治疗小儿毛细支气管炎的临床观察[J].儿科药学杂志,2014,20(4):25-27.
[30]吴海燕.综合治疗婴幼儿毛细支气管炎45例[J].河南中医,2011,31(10):1142-1143.
[31]洪丽君,刘克新,殷齐辉.加味三子养亲汤保留灌肠佐治毛细支气管炎急性发作疗效观察[J].中国中西医结合儿科学,2015,7(3):266-267.
[32]刘飞霞,黄如红,毕美芬,等.中药内服加灌肠治疗毛细支气管炎46例临床观察[J].中国中医药科技,2011,18(3):253-254.