超顺磁纳米弛豫开关传感器的检测原理及影响因素综述
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摘要
磁弛豫开关(MRS)传感器的检测是以超顺磁氧化铁纳米粒子的磁响应信号为基础。与光学方法相比,MRS不需要对样品进行复杂的预处理而对浑浊样品中进行检测,具有良好的无损性、选择性,检测过程快速、灵敏。这使MRS传感技术在食品安全、临床医学、生化分析等方面显示出了巨大的应用潜力。本文重点对超顺磁纳米弛豫开关传感器的检测原理及影响因素进行了综述,并对其发展方向及应用前景进行了展望。
Magnetic relaxation switches( MRS) are based on the signals of superparamagnetic iron oxide nanoparticles. Compared with the optical method,MRS are capable of detecting turbid samples with no pretreatment,and they have advantages of fast,non-destructive,high sensitivity and good selectivity. Therefore,MRS shows promising applications in clinical medicine,food safety,and biochemical analysis. The detection theory of superparamagnetic nanometer relaxation switch sensor and its influencing factors were summarized in this paper,and an outlook on the application of magnetic relaxation switches has been provided.
Magnetic relaxation switches( MRS) are based on the signals of superparamagnetic iron oxide nanoparticles. Compared with the optical method,MRS are capable of detecting turbid samples with no pretreatment,and they have advantages of fast,non-destructive,high sensitivity and good selectivity. Therefore,MRS shows promising applications in clinical medicine,food safety,and biochemical analysis. The detection theory of superparamagnetic nanometer relaxation switch sensor and its influencing factors were summarized in this paper,and an outlook on the application of magnetic relaxation switches has been provided.
引文
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[2] Lee H,Sun E,Ham D,et al. Nat. Med.,2008,14(8):869
[3] Perez J M,Josephson L,O'loughlin T,et al. Nat. Biotechnol.,2002,20(8):816
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[5] Cai S Y,Liang G H,Zhang P,et al. Analyst,2011,136(1):201
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[7] Zhao Y,Yao Y T,Xiao M,et al. Food Control,2013,34(2):436
[8] Chen Y P,Zou M Q,Qi C,et al. Biosens. Bioelectron.,2013,39(1):112
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[16] Ruan R S. Application of Nuclear Magnetic Resonance Technology in Food and Biological Systems,Beijing:China Light Industry Press,2009:1阮榕生.核磁共振技术在食品和生物体系中的应用.北京:中国轻工业出版社,2009:1
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[29] Koh I,Hong R,Weissleder R,et al. Anal. Chem.,2009,81(9):3618
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