乳腺癌保乳手术与改良根治术治疗早期乳腺癌的疗效及生活质量比较
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摘要
目的比较乳腺癌保乳手术与改良根治术治疗早期乳腺癌的疗效及生活质量。方法选取2017年12月～2018年12月间我院行手术治疗的乳腺癌患者64例,根据手术方法不同分为两组,保乳组共32例,采取乳腺癌保乳手术,对照组共32例,采取改良根治术。比较两组的手术时间、住院时间及术中出血量、乳房外观效果和并发症及生活质量改善情况。结果两组患者均手术顺利,保乳组的手术时间、住院时间均短于对照组,保乳组的术中出血量显著少于对照组,保乳组乳房外观的优良率显著高于对照组,保乳组患者的手术并发症少于对照组,生活质量各项评分高于对照组,差异具有显著性(P<0.05)。结论在严格掌握保乳手术的适应证前提下,保乳手术治疗早期乳腺癌较改良根治术具有创伤小、并发症少、美观效果好等优点,且能显著提高患者的生活质量水平,值得广泛推广和应用。
Objective To compare the efficacy and quality of life of breast cancer breast-conserving surgery and modified radical mastectomy in treatment of early breast cancer. Methods A total of 64 breast cancer patients who underwent surgery in our hospital from December 2017 to December 2018 were enrolled. According to different surgical methods, the patients were divided into two groups. 32 cases in the breast-preserving group were treated with breastconserving surgery for early breast cancer. 32 cases in the control group were treated with modified radical mastectomy.The operation time, hospitalization time and intraoperative blood loss, breast appearance effect and complications, and quality of life improvement were compared between the two groups. Results The operation was successful in both groups. The operation time and the hospitalization time of the breast-preserving group was shorter than that of the control group. The intraoperative blood loss of the breast-preserving group was significantly less than that in the control group. The excellent good rate of breast appearance in the breast-preserving group was significantly higher than that of the control group. The operative complications of the patients in the breast-preserving group were less than those of the control group, and the quality of life scores in the breast-preserving group were higher than those of the control group,and the difference was significant(P<0.05). Conclusion Under the premise of strict indications for breast-conserving surgery, breast-conserving surgery for early breast cancer has the advantages of less trauma, less complications, better aesthetic effect, and can significantly improve the quality of life of patients, which is worthy of promotion and application.
Objective To compare the efficacy and quality of life of breast cancer breast-conserving surgery and modified radical mastectomy in treatment of early breast cancer. Methods A total of 64 breast cancer patients who underwent surgery in our hospital from December 2017 to December 2018 were enrolled. According to different surgical methods, the patients were divided into two groups. 32 cases in the breast-preserving group were treated with breastconserving surgery for early breast cancer. 32 cases in the control group were treated with modified radical mastectomy.The operation time, hospitalization time and intraoperative blood loss, breast appearance effect and complications, and quality of life improvement were compared between the two groups. Results The operation was successful in both groups. The operation time and the hospitalization time of the breast-preserving group was shorter than that of the control group. The intraoperative blood loss of the breast-preserving group was significantly less than that in the control group. The excellent good rate of breast appearance in the breast-preserving group was significantly higher than that of the control group. The operative complications of the patients in the breast-preserving group were less than those of the control group, and the quality of life scores in the breast-preserving group were higher than those of the control group,and the difference was significant(P<0.05). Conclusion Under the premise of strict indications for breast-conserving surgery, breast-conserving surgery for early breast cancer has the advantages of less trauma, less complications, better aesthetic effect, and can significantly improve the quality of life of patients, which is worthy of promotion and application.
引文
[1]应小俊.保乳手术和改良根治术治疗早期乳腺癌的疗效对比分析[J].当代医学,2013,19(2)37-39.
[2]符坤,陈春明.保乳术与改良根治术治疗乳腺癌的疗效比较[J].当代医学,2012,18(5):52-55.
[3]汪敏.早期乳腺癌保乳手术及改良根治术的临床疗效及生活质量的比较[J].实用癌症杂志2014,29(3):321-323.
[4]余敏,徐正丰,邱涵,等.保乳术与改良根治术治疗乳腺癌患者临床疗效及预后影响的系统评价[J].安徽医药,2015,19(12):2330-2334.
[5]吴洁.早期乳腺癌改良根治术与保乳手术的疗效比较[J].实用癌症杂志,2014,29(11):1477-1478.
[6]夏冬,李显蓉,姚晖,等.早期乳腺癌患者行改良根治手术与保乳术的疗效观察[J].实用肿瘤杂志,2012,27(2):133-135.
[7]邓丁梅,王西跃,曹茵.保乳手术与改良根治术治疗早期乳腺癌的临床疗效观察[J].中国医药科学,2014,4(3):201-202.
[8]唐金海,姚宇锋.早期乳腺癌的诊断和外科治疗进展[J].中国普外基础与临床杂志,2011,18(9):913-916.
[9]李彬.早期乳腺癌患者应用保乳术和改良根治术的效果对比[J].中国现代药物应用2014,8(3):101-102.
[10]周强.保乳术与改良根治术在早期乳腺癌治疗中的效果比较[J].中国医药导报,2015,12(32):100-101.
[11]徐子迅,陈曲海.保乳手术与根治性手术对早期乳腺癌患者并发症及生存质量的影响比较[J].四川医学,2013,34(1):110-112.
[12]沈国双,窦拉加,张双元,等.保乳手术与改良根治术治疗早期乳腺癌有效性和安全性的系统评价[J].中国老年学杂志,2014,34(22):6347-6349.
[13]李伟,王冰涛,尚宏清,等.保乳手术与改良根治术治疗早期乳腺癌的临床疗效比较[J].局解手术学杂志,2014,23(1):79-81.
[14]汪青峰.早期乳腺癌保乳手术与改良根治术的对比研究[J].中国医药科学,2011,1(15):216-217.
[15]王斌,付肥郭,王学究.改良根治术及保乳术治疗早期乳腺癌的对比研究[J].实用临床医药杂志,2015,19(13):47-49.
[16]赵文生,黄安中,彭上清.保乳手术与改良根治术治疗早期乳腺癌的疗效对比[J].中国老年学杂志,2014,34(11):3005-3006.
[17]郭方东.保乳术与改良根治术对早期乳腺癌的疗效及术后生存质量比较[J].中国现代普通外科进展,2016,19(1):62-64.
[18]官上琦.早期乳腺癌行乳腺癌改良根治术治疗疗效及安全性[J].国外医药:抗生素分册,2015,36(3):133-135.
[2]符坤,陈春明.保乳术与改良根治术治疗乳腺癌的疗效比较[J].当代医学,2012,18(5):52-55.
[3]汪敏.早期乳腺癌保乳手术及改良根治术的临床疗效及生活质量的比较[J].实用癌症杂志2014,29(3):321-323.
[4]余敏,徐正丰,邱涵,等.保乳术与改良根治术治疗乳腺癌患者临床疗效及预后影响的系统评价[J].安徽医药,2015,19(12):2330-2334.
[5]吴洁.早期乳腺癌改良根治术与保乳手术的疗效比较[J].实用癌症杂志,2014,29(11):1477-1478.
[6]夏冬,李显蓉,姚晖,等.早期乳腺癌患者行改良根治手术与保乳术的疗效观察[J].实用肿瘤杂志,2012,27(2):133-135.
[7]邓丁梅,王西跃,曹茵.保乳手术与改良根治术治疗早期乳腺癌的临床疗效观察[J].中国医药科学,2014,4(3):201-202.
[8]唐金海,姚宇锋.早期乳腺癌的诊断和外科治疗进展[J].中国普外基础与临床杂志,2011,18(9):913-916.
[9]李彬.早期乳腺癌患者应用保乳术和改良根治术的效果对比[J].中国现代药物应用2014,8(3):101-102.
[10]周强.保乳术与改良根治术在早期乳腺癌治疗中的效果比较[J].中国医药导报,2015,12(32):100-101.
[11]徐子迅,陈曲海.保乳手术与根治性手术对早期乳腺癌患者并发症及生存质量的影响比较[J].四川医学,2013,34(1):110-112.
[12]沈国双,窦拉加,张双元,等.保乳手术与改良根治术治疗早期乳腺癌有效性和安全性的系统评价[J].中国老年学杂志,2014,34(22):6347-6349.
[13]李伟,王冰涛,尚宏清,等.保乳手术与改良根治术治疗早期乳腺癌的临床疗效比较[J].局解手术学杂志,2014,23(1):79-81.
[14]汪青峰.早期乳腺癌保乳手术与改良根治术的对比研究[J].中国医药科学,2011,1(15):216-217.
[15]王斌,付肥郭,王学究.改良根治术及保乳术治疗早期乳腺癌的对比研究[J].实用临床医药杂志,2015,19(13):47-49.
[16]赵文生,黄安中,彭上清.保乳手术与改良根治术治疗早期乳腺癌的疗效对比[J].中国老年学杂志,2014,34(11):3005-3006.
[17]郭方东.保乳术与改良根治术对早期乳腺癌的疗效及术后生存质量比较[J].中国现代普通外科进展,2016,19(1):62-64.
[18]官上琦.早期乳腺癌行乳腺癌改良根治术治疗疗效及安全性[J].国外医药:抗生素分册,2015,36(3):133-135.