摘要
目的:评价临床药师干预前后,注射用盐酸丙帕他莫不合理应用的改善情况。方法:调取2017年6月我院住院部注射用盐酸丙帕他莫用量及使用情况的数据进行点评,采用相同方式调取2017年12月临床药师干预后注射用盐酸丙帕他莫的应用数据进行对比分析。结果:临床药师干预后,注射用盐酸丙帕他莫使用量下降了38. 59%,各科室用药剂量均有所降低,该药品的销售金额下降,稀释终浓度、给药剂量、给药疗程等方面不合理的现象均明显改善。结论:通过临床药师干预,我院注射用盐酸丙帕他莫不合理应用的现象有所改善,但仍存在一些问题,需要持续改进。
Objective: To evaluate the improvement of the irrational use of paracetamol hydrochloride for injection before and after the intervention by clinical pharmacists. Methods: In June 2017,the detailed data of the dosage and usage of paracetamol hydrochloride for injection used in the inpatients in our hospital were collected and evaluated. After the intervention,the same method was used to compare and analyze the data of paracetamol hydrochloride for injection in December 2017. Results: After the intervention by clinical pharmacist,the application amount of paracetamol hydrochloride for injection decreased 38. 59%,the dosage was reduced in all the departments,and the sum decreased as well. The irrational uses such as the final dilution concentration,dosage and treatment course were all improved. Conclusion: Through the intervention of clinical pharmacists,the irrational use of paracetamol hydrochloride for injection in our hospital has been improved,while there are still some problems need further improvement.
引文
1李宁江,袁春晖,高恩付,等.盐酸丙帕他莫对重症监护病房危重患者镇痛效果及身体依赖性的观察[J].中国中西医结合急救杂志,2011,18(2):113-115
2 严国胜,刘泽文,刘会长.新型非甾体类镇痛药盐酸丙帕他莫的临床应用进展[J].实用临床医药杂志,2013,17(11):168-170
3 中华医学会麻醉学分会.成人术后疼痛处理专家共识[J].临床麻醉学杂志,2017,33(9):911-917
4 Eremenko AA,Kuslieva EV. Analgesic and opioid·sparing effects of intravenous paracetamol in the early period after aortocoronary bypass surgery[J]. Anesteziol Reanimatol,2008,(5):11-14
5 许红,李国春,伍伦玲,等.注射用盐酸丙帕他莫合理调配方案研究[J].中国药业,2017,26(22):8-11
6 魏立明,罗起超,贾晨.注射用盐酸丙帕他莫与5种临床常用注射液的配伍稳定性考察[J].中国现代应用药学,2016,33(2):196-199
7 方安宁,严家来,徐德祥.对乙酰氨基酚诱导肝损伤的药物保护研究[J].湘雅学院学报(医学版),2017,19(1):68-71
8 陆忠祥,邢怀阳,赵仁,等.注射用盐酸丙帕他莫的安全性试验[J].淮海医药,2008,26(5):443-445