基于中医传承辅助平台探索中医药治疗慢喉痹的用药规律
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摘要
目的应用中医传承辅助平台软件,分析和总结中医药治疗慢喉痹方剂的组方用药规律。方法收集中国知网和维普数据库中中医药治疗慢喉痹的文献,筛选出符合标准的方剂并建立数据库,应用中医传承辅助系统(V2.5)软件中集成的数据挖掘方法,分析方剂中中药用药规律。结果通过中医传承辅助平台分析筛选出的主治慢喉痹的方剂129条,对数据库的方剂进行分析,共涉及中药192味,确定了方中药物使用的频次,得出使用频次较高的药物,得到治疗慢喉痹26组核心组合,进一步聚类,得到13个新处方。结论通过中医传承辅助平台可对慢喉痹方剂数据进行分析,明确近年来治疗慢喉痹的用药规律特点。
OBJECTIVE To analyze and summarize the prescription regularity of traditional Chinese medicine(TCM)treatment for chronic pharyngitis based on traditional Chinese medicine inheritance system(TCMISS). METHODS Collected the literature in CNKI and VIP on the treatment of chronic pharyngitis by TCM and screened the proper prescriptions to establish database. Applied the data mining method integrated in the traditional Chinese inheritance system(V2.5) to analyze the prescription regularity of TCM treatment for chronic pharyngitis. RESULTS The 129 prescriptions for chronic pharyngitis treatment were screened based on the analysis of prescriptions in TCMISS. A total of 192 herbs were involved, the frequency of drug use in the prescription was determined, and the prescriptions with higher frequency and 26 groups of core combinations for chronic pharyngitis treatment were obtained. Through further clustering, 13 new prescriptions for chronic pharyngitis treatment were acquired. CONCLUSION Through analyzing the prescription data for chronic pharyngitis by TCMISS, the prescription regularity for chronic pharyngitis treatment in recent years is clarified.
OBJECTIVE To analyze and summarize the prescription regularity of traditional Chinese medicine(TCM)treatment for chronic pharyngitis based on traditional Chinese medicine inheritance system(TCMISS). METHODS Collected the literature in CNKI and VIP on the treatment of chronic pharyngitis by TCM and screened the proper prescriptions to establish database. Applied the data mining method integrated in the traditional Chinese inheritance system(V2.5) to analyze the prescription regularity of TCM treatment for chronic pharyngitis. RESULTS The 129 prescriptions for chronic pharyngitis treatment were screened based on the analysis of prescriptions in TCMISS. A total of 192 herbs were involved, the frequency of drug use in the prescription was determined, and the prescriptions with higher frequency and 26 groups of core combinations for chronic pharyngitis treatment were obtained. Through further clustering, 13 new prescriptions for chronic pharyngitis treatment were acquired. CONCLUSION Through analyzing the prescription data for chronic pharyngitis by TCMISS, the prescription regularity for chronic pharyngitis treatment in recent years is clarified.
引文
[1]熊大经,刘蓬.中医耳鼻咽喉科学[M].北京:中国中医药出版社,2012.
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[10]PENG H.Clinical observation on treating 28 cases of chronic pharyngitis in TCM[J].Clin J Chin Med(中医临床研究),2014,6(10):110-111.
[11]陈建华,吴兆怀,庞娟,等.改良玄麦甘桔汤治疗虚火喉痹30例的疗效观察[J].中国药物经济学,2014,9(3):83-84.
[12]LI J,LU P,TANG S H,et al.Analysis on composition principles of prescriptions for lung abscess by using traditional Chinese medicine inheritance system[J].Chin J Exp Tradit Med Form(中国实验方剂学杂志),2012,18(2):254-257.
[13]YANG H J,LEI Y,TANG S H,et al.Discovery,identification and optimization of new drug of Chinese medicine-the core and key design[J].World Sci Technol Mod Tradit Chin Med Mater Med(世界科学技术-中医药现代化),2011,13(1):154-158.
[14]TANG S H,LU P,LI J,et al.Composition principles of prescriptions for asthma in dictionary of Chinese medicine prescription[J].J Tradit Chin Med(中医杂志),2012,53(14):1230-1233.
[2]刘大新.浅谈对于喉痹一词的认识与思考,中华中医药学会耳鼻喉科分会第18届学术交流会暨世界中联耳鼻喉口腔科专业委员会第4届学术年会中西医结合耳鸣耳聋新进展学习班论文集[C].乌鲁木齐:中华中医药学会,2012:86-89.
[3]中国药典.一部[S].2015.
[4]WANG F Y,CHEN Y,CHEN Z Q.Study on the preparation and clinic effect of qingyan spray[J].Chin J Mod Appl Pharm(中国现代应用药学),2009,26(1):79-81.
[5]DEEPTHI M,NARSIMLOO K.Role of usage of antibiotics in pharyngitis:a prospective study[J].Int J Otorhinolaryngol Head Neck Surg,2017,3(2):303.
[6]刘大新.试论“一阴一阳结谓之喉痹”,中华中医药学会耳鼻喉科分会学术交流会暨贵州省中西医结合学会耳鼻咽喉分会第二次学术交流会论文集[C].贵阳:中华中医药学会,2013:217-220.
[7]CHEN L Y,WU H Z.Zhang jingyue's contribution to otorhinolaryngology[J].Acta Univ Tradit Med Sin Pharmacol Shanghai(上海中医药大学学报),2006,20(4):38-40.
[8]YAN Y,YAN D N.Exploration on academic thought from YOU shi laryngology[J].J Liaoning Univ Tradit Chin Med(辽宁中医药大学学报),2012,14(2):117-119.
[9]GE T,GAN L S,CHEN J J,et al.Evaluation of Chinese classic herbal formula danggui-beimu-kushen by aerosol and oral administration on chronic obstructive pulmonary mice model[J].Chin J Mod Appl Pharm(中国现代应用药学),2017,34(7):964-968.
[10]PENG H.Clinical observation on treating 28 cases of chronic pharyngitis in TCM[J].Clin J Chin Med(中医临床研究),2014,6(10):110-111.
[11]陈建华,吴兆怀,庞娟,等.改良玄麦甘桔汤治疗虚火喉痹30例的疗效观察[J].中国药物经济学,2014,9(3):83-84.
[12]LI J,LU P,TANG S H,et al.Analysis on composition principles of prescriptions for lung abscess by using traditional Chinese medicine inheritance system[J].Chin J Exp Tradit Med Form(中国实验方剂学杂志),2012,18(2):254-257.
[13]YANG H J,LEI Y,TANG S H,et al.Discovery,identification and optimization of new drug of Chinese medicine-the core and key design[J].World Sci Technol Mod Tradit Chin Med Mater Med(世界科学技术-中医药现代化),2011,13(1):154-158.
[14]TANG S H,LU P,LI J,et al.Composition principles of prescriptions for asthma in dictionary of Chinese medicine prescription[J].J Tradit Chin Med(中医杂志),2012,53(14):1230-1233.